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Volumn 9, Issue , 2007, Pages

High abundance synovial fluid proteome: Distinct profiles in health and osteoarthritis

Author keywords

[No Author keywords available]

Indexed keywords

PROTEOME; BIOLOGICAL MARKER;

EID: 34247847988     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2172     Document Type: Article
Times cited : (205)

References (88)
  • 1
    • 0036707745 scopus 로고    scopus 로고
    • Impact of osteoarthritis on individuals and society: How much disability? Social consequences and health economic implications
    • 10.1097/00002281-200209000-00017 12192258
    • Brooks PM Impact of osteoarthritis on individuals and society: How much disability? Social consequences and health economic implications Curr Opin Rheumatol 2002 14 573-577 10.1097/00002281-200209000-00017 12192258
    • (2002) Curr Opin Rheumatol , vol.14 , pp. 573-577
    • Brooks, P.M.1
  • 2
    • 0034304209 scopus 로고    scopus 로고
    • The increasing impact of arthritis on public health
    • 11032095
    • Elders MJ The increasing impact of arthritis on public health J Rheumatol Suppl 2000 60 6-8 11032095
    • (2000) J Rheumatol Suppl , vol.60 , pp. 6-8
    • Elders, M.J.1
  • 3
    • 15944406704 scopus 로고    scopus 로고
    • Pathogenesis of osteoarthritis
    • Philadelphia, PA: Elsevier/Saunders Harris ED, Ruddy S, Kelley WN 7 (xxix, 1916, lp)
    • DiCesare PE Abramson SB Pathogenesis of osteoarthritis Kelley's Textbook of Rheumatology Philadelphia, PA: Elsevier/Saunders Harris ED, Ruddy S, Kelley WN 7 2005 2v (xxix, 1916, lp)
    • (2005) Kelley's Textbook of Rheumatology
    • DiCesare, P.E.1    Abramson, S.B.2
  • 4
    • 34247849073 scopus 로고    scopus 로고
    • NCBI ftp site http://ftp.ncbi.nih.gov
  • 6
    • 0036069214 scopus 로고    scopus 로고
    • Interactive exploration of microarray gene expression patterns in a reduced dimensional space
    • 186614 12097349 10.1101/gr.225302
    • Misra J Schmitt W Hwang D Hsiao LL Gullans S Stephanopoulos G Stephanopoulos G Interactive exploration of microarray gene expression patterns in a reduced dimensional space Genome Res 2002 12 1112-1120 186614 12097349 10.1101/gr.225302
    • (2002) Genome Res , vol.12 , pp. 1112-1120
    • Misra, J.1    Schmitt, W.2    Hwang, D.3    Hsiao, L.L.4    Gullans, S.5    Stephanopoulos, G.6    Stephanopoulos, G.7
  • 7
    • 1842831283 scopus 로고    scopus 로고
    • Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers
    • 387239 15075291 10.1101/gad.1182504
    • Kho AT Zhao Q Cai Z Butte AJ Kim JY Pomeroy SL Rowitch DH Kohane IS Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers Genes Dev 2004 18 629-640 387239 15075291 10.1101/gad.1182504
    • (2004) Genes Dev , vol.18 , pp. 629-640
    • Kho, A.T.1    Zhao, Q.2    Cai, Z.3    Butte, A.J.4    Kim, J.Y.5    Pomeroy, S.L.6    Rowitch, D.H.7    Kohane, I.S.8
  • 8
    • 0034730140 scopus 로고    scopus 로고
    • Singular value decomposition for genome-wide expression data processing and modeling
    • 27718 10963673 10.1073/pnas.97.18.10101
    • Alter O Brown PO Botstein D Singular value decomposition for genome-wide expression data processing and modeling Proc Natl Acad Sci USA 2000 97 10101-10106 27718 10963673 10.1073/pnas.97.18.10101
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10101-10106
    • Alter, O.1    Brown, P.O.2    Botstein, D.3
  • 10
    • 24744467785 scopus 로고    scopus 로고
    • Consequences of disease-causing mutations on lubricin protein synthesis, secretion, and post-translational processing
    • 10.1074/jbc.M505401200 16000300
    • Rhee DK Marcelino J Al-Mayouf S Schelling DK Bartels CF Cui Y Laxer R Goldbach-Mansky R Warman ML Consequences of disease-causing mutations on lubricin protein synthesis, secretion, and post-translational processing J Biol Chem 2005 280 31325-31332 10.1074/jbc.M505401200 16000300
    • (2005) J Biol Chem , vol.280 , pp. 31325-31332
    • Rhee, D.K.1    Marcelino, J.2    Al-Mayouf, S.3    Schelling, D.K.4    Bartels, C.F.5    Cui, Y.6    Laxer, R.7    Goldbach-Mansky, R.8    Warman, M.L.9
  • 12
    • 0038561131 scopus 로고    scopus 로고
    • A method for the comprehensive proteomic analysis of membrane proteins
    • 10.1038/nbt819 12692561
    • Wu CC MacCoss MJ Howell KE Yates JR 3rd A method for the comprehensive proteomic analysis of membrane proteins Nat Biotechnol 2003 21 532-538 10.1038/nbt819 12692561
    • (2003) Nat Biotechnol , vol.21 , pp. 532-538
    • Wu, C.C.1    MacCoss, M.J.2    Howell, K.E.3    Yates III, J.R.4
  • 13
    • 0141924429 scopus 로고    scopus 로고
    • Reproducibility of quantitative proteomic analyses of complex biological mixtures by multidimensional protein identification technology
    • 10.1021/ac034120b 14708778
    • Washburn MP Ulaszek RR Yates JR 3rd Reproducibility of quantitative proteomic analyses of complex biological mixtures by multidimensional protein identification technology Anal Chem 2003 75 5054-5061 10.1021/ ac034120b 14708778
    • (2003) Anal Chem , vol.75 , pp. 5054-5061
    • Washburn, M.P.1    Ulaszek, R.R.2    Yates III, J.R.3
  • 14
    • 31644438577 scopus 로고    scopus 로고
    • Large scale protein profiling by combination of protein fractionation and multidimensional protein identification technology (MudPIT)
    • 10.1074/mcp.T500013-MCP200 16272560
    • Chen EI Hewel J Felding-Habermann B Yates JR 3rd Large scale protein profiling by combination of protein fractionation and multidimensional protein identification technology (MudPIT) Mol Cell Proteomics 2006 5 53-56 10.1074/mcp.T500013-MCP200 16272560
    • (2006) Mol Cell Proteomics , vol.5 , pp. 53-56
    • Chen, E.I.1    Hewel, J.2    Felding-Habermann, B.3    Yates III, J.R.4
  • 15
    • 33744908602 scopus 로고    scopus 로고
    • Development and characterization of a highly specific and sensitive sandwich ELISA for detection of aggrecanase-generated aggrecan fragments
    • 10.1016/j.joca.2006.01.012 16549371
    • Pratta MA Su JL Leesnitzer MA Struglics A Larsson S Lohmander LS Kumar S Development and characterization of a highly specific and sensitive sandwich ELISA for detection of aggrecanase-generated aggrecan fragments Osteoarthritis Cartilage 2006 14 702-713 10.1016/j.joca.2006.01.012 16549371
    • (2006) Osteoarthritis Cartilage , vol.14 , pp. 702-713
    • Pratta, M.A.1    Su, J.L.2    Leesnitzer, M.A.3    Struglics, A.4    Larsson, S.5    Lohmander, L.S.6    Kumar, S.7
  • 16
    • 30544448357 scopus 로고    scopus 로고
    • Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments
    • 10.1016/j.joca.2005.07.018 16188468
    • Struglics A Larsson S Pratta MA Kumar S Lark MW Lohmander LS Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments Osteoarthritis Cartilage 2006 14 101-113 10.1016/j.joca.2005.07.018 16188468
    • (2006) Osteoarthritis Cartilage , vol.14 , pp. 101-113
    • Struglics, A.1    Larsson, S.2    Pratta, M.A.3    Kumar, S.4    Lark, M.W.5    Lohmander, L.S.6
  • 17
    • 0028201015 scopus 로고
    • Changes in cartilage metabolism in arthritis are reflected by altered serum and synovial fluid levels of the cartilage proteoglycan aggrecan. Implications for pathogenesis
    • 296278 7518830
    • Poole AR Ionescu M Swan A Dieppe PA Changes in cartilage metabolism in arthritis are reflected by altered serum and synovial fluid levels of the cartilage proteoglycan aggrecan. Implications for pathogenesis J Clin Invest 1994 94 25-33 296278 7518830
    • (1994) J Clin Invest , vol.94 , pp. 25-33
    • Poole, A.R.1    Ionescu, M.2    Swan, A.3    Dieppe, P.A.4
  • 18
    • 0033050802 scopus 로고    scopus 로고
    • Changes in joint cartilage aggrecan after knee injury and in osteoarthritis
    • 10.1002/1529-0131(199904)42:3<534::AID-ANR19>3.0.CO;2-J 10088777
    • Lohmander LS Ionescu M Jugessur H Poole AR Changes in joint cartilage aggrecan after knee injury and in osteoarthritis Arthritis Rheum 1999 42 534-544 10.1002/1529-0131(199904)42:3<534::AID-ANR19>3.0.CO;2-J 10088777
    • (1999) Arthritis Rheum , vol.42 , pp. 534-544
    • Lohmander, L.S.1    Ionescu, M.2    Jugessur, H.3    Poole, A.R.4
  • 19
    • 0027064478 scopus 로고
    • Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis. Evidence for molecular heterogeneity and extensive molecular changes in disease
    • 443378 1281828
    • Rizkalla G Reiner A Bogoch E Poole AR Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis. Evidence for molecular heterogeneity and extensive molecular changes in disease J Clin Invest 1992 90 2268-2277 443378 1281828
    • (1992) J Clin Invest , vol.90 , pp. 2268-2277
    • Rizkalla, G.1    Reiner, A.2    Bogoch, E.3    Poole, A.R.4
  • 20
    • 0036151195 scopus 로고    scopus 로고
    • Expression of collagen and aggrecan genes in normal and osteoarthritic murine knee joints
    • 10.1053/joca.2001.0481 11795983
    • Chambers MG Kuffner T Cowan SK Cheah KS Mason RM Expression of collagen and aggrecan genes in normal and osteoarthritic murine knee joints Osteoarthritis Cartilage 2002 10 51-61 10.1053/joca.2001.0481 11795983
    • (2002) Osteoarthritis Cartilage , vol.10 , pp. 51-61
    • Chambers, M.G.1    Kuffner, T.2    Cowan, S.K.3    Cheah, K.S.4    Mason, R.M.5
  • 21
    • 2442699167 scopus 로고    scopus 로고
    • Up regulation of cathepsin K expression in articular chondrocytes in a transgenic mouse model for osteoarthritis
    • 10.1136/ard.2002.004671 15140771
    • Morko JP Soderstrom M Saamanen AM Salminen HJ Vuorio EI Up regulation of cathepsin K expression in articular chondrocytes in a transgenic mouse model for osteoarthritis Ann Rheum Dis 2004 63 649-655 10.1136/ ard.2002.004671 15140771
    • (2004) Ann Rheum Dis , vol.63 , pp. 649-655
    • Morko, J.P.1    Soderstrom, M.2    Saamanen, A.M.3    Salminen, H.J.4    Vuorio, E.I.5
  • 22
    • 0025220324 scopus 로고
    • Determination of cathepsins B and H in sera and synovial fluids of patients with different joint diseases
    • 2329322
    • Gabrijelcic D Annan-Prah A Rodic B Rozman B Cotic V Turk V Determination of cathepsins B and H in sera and synovial fluids of patients with different joint diseases J Clin Chem Clin Biochem 1990 28 149-153 2329322
    • (1990) J Clin Chem Clin Biochem , vol.28 , pp. 149-153
    • Gabrijelcic, D.1    Annan-Prah, A.2    Rodic, B.3    Rozman, B.4    Cotic, V.5    Turk, V.6
  • 23
    • 0023886162 scopus 로고
    • Human cathepsin B and cysteine proteinase inhibitors (CPIs) in inflammatory and metabolic joint diseases
    • 3264507
    • Lenarcic B Gabrijelcic D Rozman B Drobnic-Kosorok M Turk V Human cathepsin B and cysteine proteinase inhibitors (CPIs) in inflammatory and metabolic joint diseases Biol Chem Hoppe Seyler 1988 369 Suppl 257-261 3264507
    • (1988) Biol Chem Hoppe Seyler , vol.369 , Issue.SUPPL. , pp. 257-261
    • Lenarcic, B.1    Gabrijelcic, D.2    Rozman, B.3    Drobnic-Kosorok, M.4    Turk, V.5
  • 24
    • 0025424354 scopus 로고
    • Cathepsin B and cysteine protease inhibitors in human osteoarthritis
    • 10.1002/jor.1100080305 2324852
    • Martel-Pelletier J Cloutier JM Pelletier JP Cathepsin B and cysteine protease inhibitors in human osteoarthritis J Orthop Res 1990 8 336-344 10.1002/jor.1100080305 2324852
    • (1990) J Orthop Res , vol.8 , pp. 336-344
    • Martel-Pelletier, J.1    Cloutier, J.M.2    Pelletier, J.P.3
  • 27
    • 0033502643 scopus 로고    scopus 로고
    • Expression of cathepsin K messenger RNA in giant cells and their precursors in human osteoarthritic synovial tissues
    • 10.1002/1529-0131(199908)42:8<1588::AID-ANR4>3.0.CO;2-S 10446855
    • Dodds RA Connor JR Drake FH Gowen M Expression of cathepsin K messenger RNA in giant cells and their precursors in human osteoarthritic synovial tissues Arthritis Rheum 1999 42 1588-1593 10.1002/ 1529-0131(199908)42:8<1588::AID-ANR4>3.0.CO;2-S 10446855
    • (1999) Arthritis Rheum , vol.42 , pp. 1588-1593
    • Dodds, R.A.1    Connor, J.R.2    Drake, F.H.3    Gowen, M.4
  • 30
    • 23844482134 scopus 로고    scopus 로고
    • Proteomic characterization of human normal articular chondrocytes: A novel tool for the study of osteoarthritis and other rheumatic diseases
    • 10.1002/pmic.200402106 16035116
    • Ruiz-Romero C Lopez-Armada MJ Blanco FJ Proteomic characterization of human normal articular chondrocytes: A novel tool for the study of osteoarthritis and other rheumatic diseases Proteomics 2005 5 3048-3059 10.1002/pmic.200402106 16035116
    • (2005) Proteomics , vol.5 , pp. 3048-3059
    • Ruiz-Romero, C.1    Lopez-Armada, M.J.2    Blanco, F.J.3
  • 31
    • 33646863322 scopus 로고    scopus 로고
    • Mitochondrial proteomic characterization of human normal articular chondrocytes
    • 10.1016/j.joca.2005.12.004 16520066
    • Ruiz-Romero C Lopez-Armada MJ Blanco FJ Mitochondrial proteomic characterization of human normal articular chondrocytes Osteoarthritis Cartilage 2006 14 507-518 10.1016/j.joca.2005.12.004 16520066
    • (2006) Osteoarthritis Cartilage , vol.14 , pp. 507-518
    • Ruiz-Romero, C.1    Lopez-Armada, M.J.2    Blanco, F.J.3
  • 33
    • 0033238171 scopus 로고    scopus 로고
    • Induction of alpha1-antitrypsin synthesis in human articular chondrocytes by interleukin-6-type cytokines: Evidence for a local acute-phase response in the joint
    • 10.1002/1529-0131(199909)42:9<1936::AID-ANR20>3.0.CO;2-K 10513810
    • Fischer DC Siebertz B van de Leur E Schiwy-Bochat KH Graeve L Heinrich PC Haubeck HD Induction of alpha1-antitrypsin synthesis in human articular chondrocytes by interleukin-6-type cytokines: Evidence for a local acute-phase response in the joint Arthritis Rheum 1999 42 1936-1945 10.1002/1529-0131(199909)42:9<1936::AID-ANR20>3.0.CO;2-K 10513810
    • (1999) Arthritis Rheum , vol.42 , pp. 1936-1945
    • Fischer, D.C.1    Siebertz, B.2    van de Leur, E.3    Schiwy-Bochat, K.H.4    Graeve, L.5    Heinrich, P.C.6    Haubeck, H.D.7
  • 34
    • 0019321009 scopus 로고
    • Kinetics of association of serine proteinases with native and oxidized alpha-1-proteinase inhibitor and alpha-1-antichymotrypsin
    • 6989830
    • Beatty K Bieth J Travis J Kinetics of association of serine proteinases with native and oxidized alpha-1-proteinase inhibitor and alpha-1-antichymotrypsin J Biol Chem 1980 255 3931-3934 6989830
    • (1980) J Biol Chem , vol.255 , pp. 3931-3934
    • Beatty, K.1    Bieth, J.2    Travis, J.3
  • 35
    • 0029940075 scopus 로고    scopus 로고
    • Plasminogen activators and their inhibitors in synovial fluids from normal, osteoarthritis, and rheumatoid arthritis knees
    • 1010143 8733439
    • Belcher C Fawthrop F Bunning R Doherty M Plasminogen activators and their inhibitors in synovial fluids from normal, osteoarthritis, and rheumatoid arthritis knees Ann Rheum Dis 1996 55 230-236 1010143 8733439
    • (1996) Ann Rheum Dis , vol.55 , pp. 230-236
    • Belcher, C.1    Fawthrop, F.2    Bunning, R.3    Doherty, M.4
  • 36
    • 0026632745 scopus 로고
    • Analysis of intraarticular fibrinolytic pathways in patients with inflammatory and noninflammatory joint diseases
    • 10.1002/art.1780350806 1379429
    • Kummer JA Abbink JJ de Boer JP Roem D Nieuwenhuys EJ Kamp AM Swaak TJ Hack CE Analysis of intraarticular fibrinolytic pathways in patients with inflammatory and noninflammatory joint diseases Arthritis Rheum 1992 35 884-893 10.1002/art.1780350806 1379429
    • (1992) Arthritis Rheum , vol.35 , pp. 884-893
    • Kummer, J.A.1    Abbink, J.J.2    de Boer, J.P.3    Roem, D.4    Nieuwenhuys, E.J.5    Kamp, A.M.6    Swaak, T.J.7    Hack, C.E.8
  • 37
    • 0027412315 scopus 로고
    • Plasminogen activators and plasminogen activator inhibitors in synovial fluid. Difference between inflammatory joint disorders and osteoarthritis
    • 8441174
    • Saxne T Lecander I Geborek P Plasminogen activators and plasminogen activator inhibitors in synovial fluid. Difference between inflammatory joint disorders and osteoarthritis J Rheumatol 1993 20 91-96 8441174
    • (1993) J Rheumatol , vol.20 , pp. 91-96
    • Saxne, T.1    Lecander, I.2    Geborek, P.3
  • 38
    • 0026693646 scopus 로고
    • Depression of tissue-type plasminogen activator and enhancement of urokinase-type plasminogen activator as an expression of local inflammation
    • 1412164
    • Brommer EJ Dooijewaard G Dijkmans BA Breedveld FC Depression of tissue-type plasminogen activator and enhancement of urokinase-type plasminogen activator as an expression of local inflammation Thromb Haemost 1992 68 180-184 1412164
    • (1992) Thromb Haemost , vol.68 , pp. 180-184
    • Brommer, E.J.1    Dooijewaard, G.2    Dijkmans, B.A.3    Breedveld, F.C.4
  • 39
    • 0030805452 scopus 로고    scopus 로고
    • Plasminogen activation in synovial tissues: Differences between normal, osteoarthritis, and rheumatoid arthritis joints
    • 1752434 9370880
    • Busso N Peclat V So A Sappino AP Plasminogen activation in synovial tissues: Differences between normal, osteoarthritis, and rheumatoid arthritis joints Ann Rheum Dis 1997 56 550-557 1752434 9370880
    • (1997) Ann Rheum Dis , vol.56 , pp. 550-557
    • Busso, N.1    Peclat, V.2    So, A.3    Sappino, A.P.4
  • 40
    • 0027057950 scopus 로고
    • The role of plasminogen activators in the regulation of connective tissue metalloproteinases
    • 10.1111/j.1749-6632.1992.tb51590.x 1339240
    • Murphy G Atkinson S Ward R Gavrilovic J Reynolds JJ The role of plasminogen activators in the regulation of connective tissue metalloproteinases Ann NY Acad Sci 1992 667 1-12 10.1111/ j.1749-6632.1992.tb51590.x 1339240
    • (1992) Ann NY Acad Sci , vol.667 , pp. 1-12
    • Murphy, G.1    Atkinson, S.2    Ward, R.3    Gavrilovic, J.4    Reynolds, J.J.5
  • 41
    • 0028294626 scopus 로고
    • Binding of transforming growth factor-beta (TGF-beta) to pregnancy zone protein (PZP). Comparison to the TGF-beta-alpha 2-macroglobulin interaction
    • 10.1111/j.1432-1033.1994.tb18781.x 7513640
    • Philip A Bostedt L Stigbrand T O'Connor-McCourt MD Binding of transforming growth factor-beta (TGF-beta) to pregnancy zone protein (PZP). Comparison to the TGF-beta-alpha 2-macroglobulin interaction Eur J Biochem 1994 221 687-693 10.1111/j.1432-1033.1994.tb18781.x 7513640
    • (1994) Eur J Biochem , vol.221 , pp. 687-693
    • Philip, A.1    Bostedt, L.2    Stigbrand, T.3    O'Connor-McCourt, M.D.4
  • 42
    • 0036122157 scopus 로고    scopus 로고
    • Inhibition of insulin-like growth factor binding protein 5 proteolysis in articular cartilage and joint fluid results in enhanced concentrations of insulin-like growth factor 1 and is associated with improved osteoarthritis
    • 10.1002/art.10222 11920405
    • Clemmons DR Busby WH Jr Garmong A Schultz DR Howell DS Altman RD Karr R Inhibition of insulin-like growth factor binding protein 5 proteolysis in articular cartilage and joint fluid results in enhanced concentrations of insulin-like growth factor 1 and is associated with improved osteoarthritis Arthritis Rheum 2002 46 694-703 10.1002/ art.10222 11920405
    • (2002) Arthritis Rheum , vol.46 , pp. 694-703
    • Clemmons, D.R.1    Busby Jr., W.H.2    Garmong, A.3    Schultz, D.R.4    Howell, D.S.5    Altman, R.D.6    Karr, R.7
  • 43
  • 44
    • 0034770450 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors in rheumatic diseases
    • 1766680 11890658
    • Close DR Matrix metalloproteinase inhibitors in rheumatic diseases Ann Rheum Dis 2001 60 Suppl 3 iii62-iii67 1766680 11890658
    • (2001) Ann Rheum Dis , vol.60 , Issue.SUPPL. 3
    • Close, D.R.1
  • 45
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • 10.1038/nrc745 11990853
    • Egeblad M Werb Z New functions for the matrix metalloproteinases in cancer progression Nat Rev Cancer 2002 2 161-174 10.1038/nrc745 11990853
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 48
    • 0030839472 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibition as a novel anticancer strategy: A review with special focus on batimastat and marimastat
    • 10.1016/S0163-7258(97)00023-5 9364582
    • Rasmussen HS McCann PP Matrix metalloproteinase inhibition as a novel anticancer strategy: A review with special focus on batimastat and marimastat Pharmacol Ther 1997 75 69-75 10.1016/S0163-7258(97)00023-5 9364582
    • (1997) Pharmacol Ther , vol.75 , pp. 69-75
    • Rasmussen, H.S.1    McCann, P.P.2
  • 49
    • 14444284598 scopus 로고    scopus 로고
    • Combined analysis of studies of the effects of the matrix metalloproteinase inhibitor marimastat on serum tumor markers in advanced cancer: Selection of a biologically active and tolerable dose for longer-term studies
    • 9607566
    • Nemunaitis J Poole C Primrose J Rosemurgy A Malfetano J Brown P Berrington A Cornish A Lynch K Rasmussen H Combined analysis of studies of the effects of the matrix metalloproteinase inhibitor marimastat on serum tumor markers in advanced cancer: Selection of a biologically active and tolerable dose for longer-term studies Clin Cancer Res 1998 4 1101-1109 9607566
    • (1998) Clin Cancer Res , vol.4 , pp. 1101-1109
    • Nemunaitis, J.1    Poole, C.2    Primrose, J.3    Rosemurgy, A.4    Malfetano, J.5    Brown, P.6    Berrington, A.7    Cornish, A.8    Lynch, K.9    Rasmussen, H.10
  • 50
    • 0033603241 scopus 로고    scopus 로고
    • RAGE mediates a novel proinflammatory axis: A central cell surface receptor for S100/calgranulin polypeptides
    • 10.1016/S0092-8674(00)80801-6 10399917
    • Hofmann MA Drury S Fu C Qu W Taguchi A Lu Y Avila C Kambham N Bierhaus A Nawroth P RAGE mediates a novel proinflammatory axis: A central cell surface receptor for S100/calgranulin polypeptides Cell 1999 97 889-901 10.1016/S0092-8674(00)80801-6 10399917
    • (1999) Cell , vol.97 , pp. 889-901
    • Hofmann, M.A.1    Drury, S.2    Fu, C.3    Qu, W.4    Taguchi, A.5    Lu, Y.6    Avila, C.7    Kambham, N.8    Bierhaus, A.9    Nawroth, P.10
  • 51
    • 1442350001 scopus 로고    scopus 로고
    • Divergent pathways of gene expression are activated by the RAGE ligands S100b and AGE-BSA
    • 10.2337/diabetes.53.3.743 14988260
    • Valencia JV Mone M Zhang J Weetall M Buxton FP Hughes TE Divergent pathways of gene expression are activated by the RAGE ligands S100b and AGE-BSA Diabetes 2004 53 743-751 10.2337/diabetes.53.3.743 14988260
    • (2004) Diabetes , vol.53 , pp. 743-751
    • Valencia, J.V.1    Mone, M.2    Zhang, J.3    Weetall, M.4    Buxton, F.P.5    Hughes, T.E.6
  • 52
    • 0028304625 scopus 로고
    • Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins
    • 8144582
    • Yan SD Schmidt AM Anderson GM Zhang J Brett J Zou YS Pinsky D Stern D Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins J Biol Chem 1994 269 9889-9897 8144582
    • (1994) J Biol Chem , vol.269 , pp. 9889-9897
    • Yan, S.D.1    Schmidt, A.M.2    Anderson, G.M.3    Zhang, J.4    Brett, J.5    Zou, Y.S.6    Pinsky, D.7    Stern, D.8
  • 53
    • 0030859290 scopus 로고    scopus 로고
    • Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress
    • 10.1074/jbc.272.28.17810 9211935
    • Lander HM Tauras JM Ogiste JS Hori O Moss RA Schmidt AM Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress J Biol Chem 1997 272 17810-17814 10.1074/jbc.272.28.17810 9211935
    • (1997) J Biol Chem , vol.272 , pp. 17810-17814
    • Lander, H.M.1    Tauras, J.M.2    Ogiste, J.S.3    Hori, O.4    Moss, R.A.5    Schmidt, A.M.6
  • 54
    • 23644436200 scopus 로고    scopus 로고
    • Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis
    • 1488730 16052547 10.1002/art.21199
    • Loeser RF Yammani RR Carlson CS Chen H Cole A Im HJ Bursch LS Yan SD Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis Arthritis Rheum 2005 52 2376-2385 1488730 16052547 10.1002/art.21199
    • (2005) Arthritis Rheum , vol.52 , pp. 2376-2385
    • Loeser, R.F.1    Yammani, R.R.2    Carlson, C.S.3    Chen, H.4    Cole, A.5    Im, H.J.6    Bursch, L.S.7    Yan, S.D.8
  • 55
    • 0033538569 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways
    • 10.1074/jbc.274.28.19919 10391939
    • Huttunen HJ Fages C Rauvala H Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways J Biol Chem 1999 274 19919-19924 10.1074/ jbc.274.28.19919 10391939
    • (1999) J Biol Chem , vol.274 , pp. 19919-19924
    • Huttunen, H.J.1    Fages, C.2    Rauvala, H.3
  • 57
    • 0035159165 scopus 로고    scopus 로고
    • Vitamin E: Protective role of a Janus molecule
    • 10.1096/fj.01-0258rev 11689457
    • Ricciarelli R Zingg JM Azzi A Vitamin E: Protective role of a Janus molecule FASEB J 2001 15 2314-2325 10.1096/fj.01-0258rev 11689457
    • (2001) FASEB J , vol.15 , pp. 2314-2325
    • Ricciarelli, R.1    Zingg, J.M.2    Azzi, A.3
  • 59
    • 26944445883 scopus 로고    scopus 로고
    • Clusterin inhibits apoptosis by interacting with activated Bax
    • 10.1038/ncb1291 16113678
    • Zhang H Kim JK Edwards CA Xu Z Taichman R Wang CY Clusterin inhibits apoptosis by interacting with activated Bax Nat Cell Biol 2005 7 909-915 10.1038/ncb1291 16113678
    • (2005) Nat Cell Biol , vol.7 , pp. 909-915
    • Zhang, H.1    Kim, J.K.2    Edwards, C.A.3    Xu, Z.4    Taichman, R.5    Wang, C.Y.6
  • 60
    • 0025472394 scopus 로고
    • Kallikreins and kinins: Mediators in inflammatory joint disease?
    • 2205284
    • Worthy K Figueroa CD Dieppe PA Bhoola KD Kallikreins and kinins: mediators in inflammatory joint disease? Int J Exp Pathol 1990 71 587-601 2205284
    • (1990) Int J Exp Pathol , vol.71 , pp. 587-601
    • Worthy, K.1    Figueroa, C.D.2    Dieppe, P.A.3    Bhoola, K.D.4
  • 61
    • 0026688010 scopus 로고
    • Kinins: Key mediators in inflammatory arthritis?
    • 10.1093/rheumatology/31.8.509 1643449
    • Bhoola KD Elson CJ Dieppe PA Kinins: Key mediators in inflammatory arthritis? Br J Rheumatol 1992 31 509-518 10.1093/rheumatology/31.8.509 1643449
    • (1992) Br J Rheumatol , vol.31 , pp. 509-518
    • Bhoola, K.D.1    Elson, C.J.2    Dieppe, P.A.3
  • 62
    • 0025833323 scopus 로고
    • Mechanism of coronary vasodilation produced by bradykinin
    • 1645623
    • Pelc LR Gross GJ Warltier DC Mechanism of coronary vasodilation produced by bradykinin Circulation 1991 83 2048-2056 1645623
    • (1991) Circulation , vol.83 , pp. 2048-2056
    • Pelc, L.R.1    Gross, G.J.2    Warltier, D.C.3
  • 63
    • 0022391199 scopus 로고
    • Cultured endothelial cells synthesize both platelet-activating factor and prostacyclin in response to histamine, bradykinin, and adenosine triphosphate
    • 423763 2862164
    • McIntyre TM Zimmerman GA Satoh K Prescott SM Cultured endothelial cells synthesize both platelet-activating factor and prostacyclin in response to histamine, bradykinin, and adenosine triphosphate J Clin Invest 1985 76 271-280 423763 2862164
    • (1985) J Clin Invest , vol.76 , pp. 271-280
    • McIntyre, T.M.1    Zimmerman, G.A.2    Satoh, K.3    Prescott, S.M.4
  • 64
    • 0030942022 scopus 로고    scopus 로고
    • Activation of the kallikrein-kinin system in arthritis and enterocolitis in genetically susceptible rats: Modulation by a selective plasma kallikrein inhibitor
    • 9010912
    • Colman RW Stadnicki A Kettner CA Adam AA DeLa Cadena RA Sartor RB Activation of the kallikrein-kinin system in arthritis and enterocolitis in genetically susceptible rats: Modulation by a selective plasma kallikrein inhibitor Proc Assoc Am Physicians 1997 109 10-22 9010912
    • (1997) Proc Assoc Am Physicians , vol.109 , pp. 10-22
    • Colman, R.W.1    Stadnicki, A.2    Kettner, C.A.3    Adam, A.A.4    DeLa Cadena, R.A.5    Sartor, R.B.6
  • 65
    • 0023201891 scopus 로고
    • Assessment of kininases in rheumatic diseases and the effect of therapeutic agents
    • 10.1002/art.1780300203 3030335
    • Sheikh IA Kaplan AP Assessment of kininases in rheumatic diseases and the effect of therapeutic agents Arthritis Rheum 1987 30 138-145 10.1002/ art.1780300203 3030335
    • (1987) Arthritis Rheum , vol.30 , pp. 138-145
    • Sheikh, I.A.1    Kaplan, A.P.2
  • 66
    • 0030805903 scopus 로고    scopus 로고
    • Generation of kinins in synovial fluid from patients with arthropathy
    • 10.1016/S0162-3109(97)00023-4 9228548
    • Bond AP Lemon M Dieppe PA Bhoola KD Generation of kinins in synovial fluid from patients with arthropathy Immunopharmacology 1997 36 209-216 10.1016/S0162-3109(97)00023-4 9228548
    • (1997) Immunopharmacology , vol.36 , pp. 209-216
    • Bond, A.P.1    Lemon, M.2    Dieppe, P.A.3    Bhoola, K.D.4
  • 68
    • 0016385833 scopus 로고
    • Rheumatoid arthritis. Biosynthesis of complement proteins by synovial tissues
    • 4133295
    • Ruddy S Colten HR Rheumatoid arthritis. Biosynthesis of complement proteins by synovial tissues N Engl J Med 1974 290 1284-1288 4133295
    • (1974) N Engl J Med , vol.290 , pp. 1284-1288
    • Ruddy, S.1    Colten, H.R.2
  • 69
    • 0024236061 scopus 로고
    • Synovial fibroblast-like cells synthesize seven proteins of the complement system
    • 10.1002/art.1780311104 3142487
    • Katz Y Strunk RC Synovial fibroblast-like cells synthesize seven proteins of the complement system Arthritis Rheum 1988 31 1365-1370 10.1002/art.1780311104 3142487
    • (1988) Arthritis Rheum , vol.31 , pp. 1365-1370
    • Katz, Y.1    Strunk, R.C.2
  • 70
    • 0025995227 scopus 로고
    • Gene expression (collagenase, tissue inhibitor of metalloproteinases, complement, and HLA-DR) in rheumatoid arthritis and osteoarthritis synovium. Quantitative analysis and effect of intraarticular corticosteroids
    • 10.1002/art.1780340905 1657009
    • Firestein GS Paine MM Littman BH Gene expression (collagenase, tissue inhibitor of metalloproteinases, complement, and HLA-DR) in rheumatoid arthritis and osteoarthritis synovium. Quantitative analysis and effect of intraarticular corticosteroids Arthritis Rheum 1991 34 1094-1105 10.1002/art.1780340905 1657009
    • (1991) Arthritis Rheum , vol.34 , pp. 1094-1105
    • Firestein, G.S.1    Paine, M.M.2    Littman, B.H.3
  • 71
    • 0028916864 scopus 로고
    • Complement components C1q, C1r/C1s, and C1INH in rheumatoid arthritis. Correlation of in situ hybridization and northern blot results with function and protein concentration in synovium and primary cell cultures
    • 10.1002/art.1780380406 7718002
    • Breitner S Storkel S Reichel W Loos M Complement components C1q, C1r/ C1s, and C1INH in rheumatoid arthritis. Correlation of in situ hybridization and northern blot results with function and protein concentration in synovium and primary cell cultures Arthritis Rheum 1995 38 492-498 10.1002/art.1780380406 7718002
    • (1995) Arthritis Rheum , vol.38 , pp. 492-498
    • Breitner, S.1    Storkel, S.2    Reichel, W.3    Loos, M.4
  • 72
    • 0025736205 scopus 로고
    • C3 activation products, C3 containing immune complexes, the terminal complement complex and native C9 in patients with rheumatoid arthritis
    • 2068540
    • Olmez U Garred P Mollnes TE Harboe M Berntzen HB Munthe E C3 activation products, C3 containing immune complexes, the terminal complement complex and native C9 in patients with rheumatoid arthritis Scand J Rheumatol 1991 20 183-189 2068540
    • (1991) Scand J Rheumatol , vol.20 , pp. 183-189
    • Olmez, U.1    Garred, P.2    Mollnes, T.E.3    Harboe, M.4    Berntzen, H.B.5    Munthe, E.6
  • 73
    • 0033368617 scopus 로고    scopus 로고
    • Complement activation following oxidative stress
    • 10.1016/S0161-5890(99)00116-9 10698348
    • Collard CD Lekowski R Jordan JE Agah A Stahl GL Complement activation following oxidative stress Mol Immunol 1999 36 941-948 10.1016/ S0161-5890(99)00116-9 10698348
    • (1999) Mol Immunol , vol.36 , pp. 941-948
    • Collard, C.D.1    Lekowski, R.2    Jordan, J.E.3    Agah, A.4    Stahl, G.L.5
  • 74
    • 0023931715 scopus 로고
    • Relation between synovial fluid C3 degradation products and local joint inflammation in rheumatoid arthritis, osteoarthritis, and crystal associated arthropathy
    • 1003482 2833185
    • Doherty M Richards N Hornby J Powell R Relation between synovial fluid C3 degradation products and local joint inflammation in rheumatoid arthritis, osteoarthritis, and crystal associated arthropathy Ann Rheum Dis 1988 47 190-197 1003482 2833185
    • (1988) Ann Rheum Dis , vol.47 , pp. 190-197
    • Doherty, M.1    Richards, N.2    Hornby, J.3    Powell, R.4
  • 75
    • 0026782676 scopus 로고
    • Terminal complement complex in synovial tissue from patients affected by rheumatoid arthritis, osteoarthritis and acute joint trauma
    • 1458695
    • Corvetta A Pomponio G Rinaldi N Luchetti MM Di Loreto C Stramazzotti D Terminal complement complex in synovial tissue from patients affected by rheumatoid arthritis, osteoarthritis and acute joint trauma Clin Exp Rheumatol 1992 10 433-438 1458695
    • (1992) Clin Exp Rheumatol , vol.10 , pp. 433-438
    • Corvetta, A.1    Pomponio, G.2    Rinaldi, N.3    Luchetti, M.M.4    Di Loreto, C.5    Stramazzotti, D.6
  • 76
    • 0030065684 scopus 로고    scopus 로고
    • Regulation of early complement components C3 and C4 in the synovium
    • 170239 8770496
    • Collins T Winkelstein JA Sullivan KE Regulation of early complement components C3 and C4 in the synovium Clin Diagn Lab Immunol 1996 3 5-9 170239 8770496
    • (1996) Clin Diagn Lab Immunol , vol.3 , pp. 5-9
    • Collins, T.1    Winkelstein, J.A.2    Sullivan, K.E.3
  • 77
    • 0023615844 scopus 로고
    • A growing family of collagens in articular cartilage: Identification of 5 genetically distinct types
    • Spec No 25 27 3625672
    • Eyre DR Wu JJ Apone S A growing family of collagens in articular cartilage: Identification of 5 genetically distinct types J Rheumatol 1987 14 Spec No 25 27 3625672
    • (1987) J Rheumatol , vol.14
    • Eyre, D.R.1    Wu, J.J.2    Apone, S.3
  • 78
    • 0031978312 scopus 로고    scopus 로고
    • Increased content of type-VI collagen epitopes in human osteoarthritic cartilage: Quantitation by inhibition ELISA
    • 10.1002/jor.1100160116 9565079
    • Swoboda B Pullig O Kirsch T Kladny B Steinhauser B Weseloh G Increased content of type-VI collagen epitopes in human osteoarthritic cartilage: quantitation by inhibition ELISA J Orthop Res 1998 16 96-99 10.1002/ jor.1100160116 9565079
    • (1998) J Orthop Res , vol.16 , pp. 96-99
    • Swoboda, B.1    Pullig, O.2    Kirsch, T.3    Kladny, B.4    Steinhauser, B.5    Weseloh, G.6
  • 79
    • 0028078658 scopus 로고
    • Release of cartilage oligomeric matrix protein (COMP) into joint fluid after knee injury and in osteoarthritis
    • 1005235 8311563
    • Lohmander LS Saxne T Heinegard DK Release of cartilage oligomeric matrix protein (COMP) into joint fluid after knee injury and in osteoarthritis Ann Rheum Dis 1994 53 8-13 1005235 8311563
    • (1994) Ann Rheum Dis , vol.53 , pp. 8-13
    • Lohmander, L.S.1    Saxne, T.2    Heinegard, D.K.3
  • 80
    • 0027450967 scopus 로고
    • Release of cartilage macromolecules into the synovial fluid in patients with acute and prolonged phases of reactive arthritis
    • 10.1002/art.1780360105 7678742
    • Saxne T Glennas A Kvien TK Melby K Heinegard D Release of cartilage macromolecules into the synovial fluid in patients with acute and prolonged phases of reactive arthritis Arthritis Rheum 1993 36 20-25 10.1002/art.1780360105 7678742
    • (1993) Arthritis Rheum , vol.36 , pp. 20-25
    • Saxne, T.1    Glennas, A.2    Kvien, T.K.3    Melby, K.4    Heinegard, D.5
  • 82
    • 0035783015 scopus 로고    scopus 로고
    • Cartilage proteoglycans
    • 10.1006/scdb.2000.0243 11292372
    • Knudson CB Knudson W Cartilage proteoglycans Semin Cell Dev Biol 2001 12 69-78 10.1006/scdb.2000.0243 11292372
    • (2001) Semin Cell Dev Biol , vol.12 , pp. 69-78
    • Knudson, C.B.1    Knudson, W.2
  • 83
    • 0034920893 scopus 로고    scopus 로고
    • Homology of lubricin and superficial zone protein (SZP): Products of megakaryocyte stimulating factor (MSF) gene expression by human synovial fibroblasts and articular chondrocytes localized to chromosome 1q25
    • 10.1016/S0736-0266(00)00040-1 11518279
    • Jay GD Tantravahi U Britt DE Barrach HJ Cha CJ Homology of lubricin and superficial zone protein (SZP): Products of megakaryocyte stimulating factor (MSF) gene expression by human synovial fibroblasts and articular chondrocytes localized to chromosome 1q25 J Orthop Res 2001 19 677-687 10.1016/S0736-0266(00)00040-1 11518279
    • (2001) J Orthop Res , vol.19 , pp. 677-687
    • Jay, G.D.1    Tantravahi, U.2    Britt, D.E.3    Barrach, H.J.4    Cha, C.J.5
  • 84
    • 0032483330 scopus 로고    scopus 로고
    • A novel cartilage protein (CILP) present in the mid-zone of human articular cartilage increases with age
    • 10.1074/jbc.273.36.23463 9722583
    • Lorenzo P Bayliss MT Heinegard D A novel cartilage protein (CILP) present in the mid-zone of human articular cartilage increases with age J Biol Chem 1998 273 23463-23468 10.1074/jbc.273.36.23463 9722583
    • (1998) J Biol Chem , vol.273 , pp. 23463-23468
    • Lorenzo, P.1    Bayliss, M.T.2    Heinegard, D.3
  • 85
    • 0032483377 scopus 로고    scopus 로고
    • Cloning and deduced amino acid sequence of a novel cartilage protein (CILP) identifies a proform including a nucleotide pyrophosphohydrolase
    • 10.1074/jbc.273.36.23469 9722584
    • Lorenzo P Neame P Sommarin Y Heinegard D Cloning and deduced amino acid sequence of a novel cartilage protein (CILP) identifies a proform including a nucleotide pyrophosphohydrolase J Biol Chem 1998 273 23469-23475 10.1074/jbc.273.36.23469 9722584
    • (1998) J Biol Chem , vol.273 , pp. 23469-23475
    • Lorenzo, P.1    Neame, P.2    Sommarin, Y.3    Heinegard, D.4
  • 86
    • 5444264829 scopus 로고    scopus 로고
    • Chondrocyte senescence, joint loading and osteoarthritis
    • 10.1097/01.blo.0000143818.74887.b1 15480082
    • Martin JA Brown TD Heiner AD Buckwalter JA Chondrocyte senescence, joint loading and osteoarthritis Clin Orthop Relat Res 2004 427 Suppl S96-S103 10.1097/01.blo.0000143818.74887.b1 15480082
    • (2004) Clin Orthop Relat Res , Issue.SUPPL.
    • Martin, J.A.1    Brown, T.D.2    Heiner, A.D.3    Buckwalter, J.A.4
  • 87
    • 0034020365 scopus 로고    scopus 로고
    • The disproportionate impact of chronic arthralgia and arthritis among women
    • 10.1097/00003086-200003000-00018 10738425
    • Buckwalter JA Lappin DR The disproportionate impact of chronic arthralgia and arthritis among women Clin Orthop Relat Res 2000 372 159-168 10.1097/00003086-200003000-00018 10738425
    • (2000) Clin Orthop Relat Res , vol.372 , pp. 159-168
    • Buckwalter, J.A.1    Lappin, D.R.2
  • 88
    • 0031602467 scopus 로고    scopus 로고
    • Articular cartilage: Degeneration and osteoarthritis, repair, regeneration, and transplantation
    • 9571450
    • Buckwalter JA Mankin HJ Articular cartilage: Degeneration and osteoarthritis, repair, regeneration, and transplantation Instr Course Lect 1998 47 487-504 9571450
    • (1998) Instr Course Lect , vol.47 , pp. 487-504
    • Buckwalter, J.A.1    Mankin, H.J.2


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