Consequences of disease-causing mutations on lubricin protein synthesis, secretion, and post-translational processing

Journal of Biological Chemistry

Volumn 280, Issue 35, 2005, Pages 31325-31332

  Rhee, David K ^a   Marcelino, Jose ^a   Al Mayou, Sulaiman ^b   Schelling, Deborah K ^a   Bartels, Cynthia F ^a   Cui, Yajun ^a   Laxer, Ronald ^c   Goldbach Mansky, Raphaela ^d   Warman, Matthew L ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBODIES; BIOSYNTHESIS; DISEASES; LIVING SYSTEMS STUDIES; MUTAGENESIS;

CARBOXYL-TERMINAL; FRAMESHIFT; PROTEOGLYCAN; SUBTILISIN-LIKE PROPROTEIN CONVERTASE (SPC);

PROTEINS;

GENE PRODUCT; HEMOPEXIN; LUBRICATING AGENT; LUBRICIN; MUCIN; PROPROTEIN CONVERTASE 1; PROTEIN; PROTEOGLYCAN; SUBTILISIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; AUTOSOMAL RECESSIVE INHERITANCE; CARBOXY TERMINAL SEQUENCE; DISULFIDE BOND; FRAMESHIFT MUTATION; GENE; HUMAN; HUMAN CELL; MUTATION; NONSENSE MUTATION; PRG4 GENE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN SYNTHESIS; SYNOVIOCYTE;

AMINO ACID MOTIFS; ANIMALS; ANTIBODIES; CERCOPITHECUS AETHIOPS; COS CELLS; DISULFIDES; EPITOPES; GLYCOPROTEINS; HUMANS; JOINT DISEASES; MUTATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; SYNDROME; SYNOVIAL FLUID;

ORYCTOLAGUS CUNICULUS;

EID: 24744467785     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M505401200     Document Type: Article

References (31)

1. Swann, D. A., Sotman, S., Dixon, M., and Brooks, C. (1977) Biochem. J. 161, 473-485
2. Swann, D. A., Silver, F. H., Slayter, H. S., Stafford, W., and Shore, E. (1985) Biochem. J. 225, 195-201
3. Schumacher, B. L., Block, J. A., Schmid, T. M., Aydelotte, M. B., and Kuettner, K. E. (1994) Arch. Biochem. Biophys. 311, 144-152
4. Schumacher, B. L., Hughes, C. E., Kuettner, K. E., Caterson, B., and Aydelotte, M. B. (1999) J. Orthop. Res. 17, 110-120
5. Flannery, C. R., Hughes, C. E., Schumacher, B. L., Tudor, D., Aydelotte, M. B., Kuettner, K. E., and Caterson, B. (1999) Biochem. Biophys. Res. Commun. 254, 535-541
6. Merberg, D., Fitz, L., and Temple, P. (1993) in Biology of Vitronectins and Their Receptors (Preissner, K., Rosenblattt, S., Kost, C., Wegerhoff, J., and Mosher, D., eds) pp. 45-54, Elsevier Science Publishers BV, Amsterdam, The Netherlands
7. Liu, Y. J., Lu, S. H., Xu, B., Yang, R. C., Ren, Q., Liu, B., Li, B., Lu, M., Yan, F. Y., Han, Z. B., and Han, Z. C. (2004) Blood 103, 4449-4456
8. Rhee, D. K., Marcelino, J., Baker, M., Gong, Y., Smits, P., Lefebvre, V., Jay, G. D., Stewart, M., Wang, H., Warman, M. L., and Carpten, J. D. (2005) J. Clin. Invest. 115, 622-631
9. Schroeck, F., Arroyo de Prada, N., Sperl, S., Schmitt, M., and Viktor, M. (2002) Biol. Chem. 383, 1143-1149
10. Sidenius, N., and Blasi, F. (2000) FEBS Lett. 470, 40-46
11. Deng, G., Curriden, S. A., Hu, G., Czekay, R. P., and Loskutoff, D. J. (2001) J. Cell. Physiol. 189, 23-33
12. Murphy, G., and Knauper, V. (1997) Matrix Biol. 15, 511-518
13. Seger, D., and Shaltiel, S. (2000) FEBS Lett. 480, 169-174
14. Matsuda, A., Itoh, Y., Koshikawa, N., Akizawa, T., Yana, I., and Seiki, M. (2003) J. Biol. Chem. 278, 36350-36357
15. Jay, G. D., Tantravahi, U., Britt, D. E., Barrach, H. J., and Cha, C. J. (2001) J. Orthop. Res. 19, 677-687
16. Jay, G. D. (1992) Connect. Tissue Res. 28, 71-88
17. Marcelino, J., Carpten, J. D., Suwairi, W. M., Gutierrez, O. M., Schwartz, S., Robbins, C., Sood, R., Makalowska, I., Baxevanis, A., Johnstone, B., Laxer, R. M., Zemel, L., Kim, C. A., Herd, J. K., Ihle, J., Williams, C., Johnson, M., Raman, V., Alonso, L. G., Brunoni, D., Gerstein, A., Papadopoulos, N., Bahabri, S. A., Trent, J. M., and Wannan, M. L. (1999) Nat. Genet. 23, 319-322
18. Bahabri, S. A., Suwairi, W. M., Laxer, R. M., Polinkovsky, A., Dalaan, A. A., and Warman, M. L. (1998) Arthritis Rheum. 41, 730-735
19. Ikegawa, S., Sano, M., Koshizuka, Y., and Nakamura, Y. (2000) Cytogenet. Cell Genet. 90, 291-297
20. Constam, D. B., and Robertson, E. J. (1999) J. Cell Biol. 144, 139-149
21. Hentze, M. W., and Kulozik, A. E. (1999) Cell 96, 307-310
22. Schvartz, I., Seger, D., and Shaltiel, S. (1999) Int. J. Biochem. Cell Biol. 31, 539-544
23. Gomis-Ruth, F. X., Gohlke, U., Betz, M., Knauper, V., Murphy, G., Lopez-Otin, C., and Bode, W. (1996) J. Mol. Biol. 264, 556-566
24. Elsaid, K. A., Jay, G. D., Warman, M. L., Rhee, D. K., and Chichester, C. O. (2005) Arthritis Rheum., 52, 1746-1755
25. Su, J. L., Schumacher, B. L., Lindley, K. M., Soloveychik, V., Burkhart, W., Triantafillou, J. A., Kuettner, K., and Schmid, T. (2001) Hybridoma 20, 149-157
26. Rees, S. G., Davies, J. E., Tudor, D., Flannery, C. R., Hughes, C. E., Dent, C. M., and Caterson, B. (2002) Matrix Biol. 21, 593-602
27. Chain, D., Korc-Grodzicki, B., Kreizman, T., and Shaltiel, S. (1990) FEBS Lett. 269, 221-225
28. Jay, G. D., Lane, B. P., and Sokoloff, L. (1992) Connect. Tissue Res. 28, 245-255
29. Perez-Vilar, J., and Hill, R. L. (1999) J. Biol. Chem. 274, 31751-31754
30. Blanchette, F., Day, R., Dong, W., Laprise, M. H., and Dubois, C. M. (1997) J. Clin. Invest. 99, 1974-1983
31. Sancho, D., Gomez, M., Viedma, F., Esplugues, E., Gordon-Alonso, M., Garcia- Lopez, M. A., de la Fuente, H., Martinez, A. C., Lauzurica, P., and Sanchez-Madrid, F. (2003) J. Clin. Invest. 112, 872-882