Molecular interaction of droperidol with human ether-a-go-go-related gene channels: Prolongation of action potential duration without inducing early afterdepolarization

Anesthesiology

Volumn 106, Issue 5, 2007, Pages 967-976

  Schwoerer, Alexander P ^a   Blütner, Carmen ^a   Brandt, Sven ^a   Binder, Stephan ^a   Siebrands, Cornelia C ^a   Ehmke, Heimo ^a   Friederich, Patrick ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DROPERIDOL; MUTANT PROTEIN; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL HERG;

ANIMAL CELL; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG MECHANISM; DRUG PROTEIN BINDING; ELECTRIC CURRENT; ELECTRIC POTENTIAL; GUINEA PIG; HEART DEPOLARIZATION; HEART MUSCLE CELL; MOLECULAR DYNAMICS; NONHUMAN; OOCYTE; PATCH CLAMP; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STEADY STATE; VOLTAGE CLAMP; WILD TYPE; XENOPUS LAEVIS;

ACTION POTENTIALS; ANIMALS; CALCIUM CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; DROPERIDOL; ETHER-A-GO-GO POTASSIUM CHANNELS; GUINEA PIGS; HUMANS; ION CHANNEL GATING; KCNQ1 POTASSIUM CHANNEL; MALE; MYOCYTES, CARDIAC; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, VOLTAGE-GATED; TIME FACTORS;

EID: 34247603062     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/01.anes.0000265156.09438.56     Document Type: Article

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