Inhibitory effect on replicative DNA polymerases, human cancer cell proliferation, and in vivo anti-tumor activity by glycolipids from spinach

Current Medicinal Chemistry

Volumn 14, Issue 9, 2007, Pages 955-967

  Maeda, Naoki ^a   Hada, Takahiko ^b   Yoshida, Hiromi ^a   Mizushina, Yoshiyuki ^a  

^a KOBE GAKUIN UNIVERSITY   (Japan)

^b Hada Giken Co Ltd   (Japan)

Author keywords

Anti tumor activity; Digalactosyl diacylglycerol (DGDG); DNA polymerase; Glycolipids; Inhibitor; Monogalactosyl diacylglycerol (MGDG); Spinach; Sulfoquinovosyl diacylglycerol (SQDG)

Indexed keywords

ANTINEOPLASTIC AGENT; DEOXYRIBONUCLEASE; DIGALACTOSYLDIGLYCERIDE; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE BETA; DNA DIRECTED DNA POLYMERASE DELTA; DNA DIRECTED DNA POLYMERASE EPSILON; DNA DIRECTED DNA POLYMERASE GAMMA; DNA DIRECTED DNA POLYMERASE LAMBDA; DNA POLYMERASE; DNA PRIMASE; GALACTOSYLDIACYLGLYCEROL; GLYCOLIPID; NUCLEOTIDYLTRANSFERASE; POLYNUCLEOTIDE 5' HYDROXYL KINASE; RNA POLYMERASE; RNA POLYMERASE T7; SULFOQUINOVOSYDIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CELL CYCLE ARREST; CELL GROWTH; CELL PROLIFERATION; COLUMN CHROMATOGRAPHY; DNA REPLICATION; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; HELA CELL; HISTOPATHOLOGY; HUMAN; IN VIVO STUDY; NONHUMAN; NUDE MOUSE; REVIEW; SOLID TUMOR; SPINACH; STRUCTURE ACTIVITY RELATION; TUMOR NECROSIS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOLOGICAL ASSAY; CELL GROWTH PROCESSES; DNA-DIRECTED DNA POLYMERASE; ENZYME INHIBITORS; GLYCOLIPIDS; HELA CELLS; HISTOCYTOCHEMISTRY; HUMANS; INHIBITORY CONCENTRATION 50; MICE; MICE, NUDE; SPINACIA OLERACEA;

EID: 34247558520     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986707780362952     Document Type: Review

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