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Volumn 272, Issue 17, 2005, Pages 4349-4361

Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase β

Author keywords

Binding site; DNA polymerase ; Inhibitor; NMR chemical shift mapping; Sulfoquinovosylmonoacylglycerol

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA; DNA POLYMERASE; FATTY ACID; MONOACYLGLYCEROL; MYRISTOLEIC ACID; SULFOQUINOVOSYLGLYCEROL; SULFOQUINOVOSYLMONOACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 24644443315     PISSN: 1742464X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2005.04848.x     Document Type: Article
Times cited : (10)

References (37)
  • 2
    • 0032440708 scopus 로고    scopus 로고
    • Lithocholic acid, a putative tumor promoter, inhibits mammalian DNA polymerase beta
    • Ogawa A, Murate T, Suzuki M, Nimura Y & Yoshida S (1998) Lithocholic acid, a putative tumor promoter, inhibits mammalian DNA polymerase beta. Jpn J Cancer Res 89, 1154-1159.
    • (1998) Jpn J Cancer Res , vol.89 , pp. 1154-1159
    • Ogawa, A.1    Murate, T.2    Suzuki, M.3    Nimura, Y.4    Yoshida, S.5
  • 4
    • 0037193179 scopus 로고    scopus 로고
    • Novel anti-inflammatory compounds from Rubus sieboldii, triterpenoids, are inhibitors of mammalian DNA polymerases
    • Murakami C, Ishijima K, Hirota M, Sakaguchi K, Yoshida H & Mizushina Y (2002) Novel anti-inflammatory compounds from Rubus sieboldii, triterpenoids, are inhibitors of mammalian DNA polymerases. Biochim Biophys Acta 1596, 193-200.
    • (2002) Biochim Biophys Acta , vol.1596 , pp. 193-200
    • Murakami, C.1    Ishijima, K.2    Hirota, M.3    Sakaguchi, K.4    Yoshida, H.5    Mizushina, Y.6
  • 7
    • 0031976708 scopus 로고    scopus 로고
    • Sulfoquinovosyldiacylglycerol, KM043, a new potent inhibitor of eukaryotic DNA polymerases and HIV-reverse transcriptase type 1 from a marine red alga, Gigartina tenella
    • Ohta K, Mizushina Y, Hirata N, Takemura M, Sugawara F, Matsukage A, Yoshida S & Sakaguchi K (1998) Sulfoquinovosyldiacylglycerol, KM043, a new potent inhibitor of eukaryotic DNA polymerases and HIV-reverse transcriptase type 1 from a marine red alga, Gigartina tenella. Chem Pharm Bull (Tokyo) 46, 684-686.
    • (1998) Chem Pharm Bull (Tokyo) , vol.46 , pp. 684-686
    • Ohta, K.1    Mizushina, Y.2    Hirata, N.3    Takemura, M.4    Sugawara, F.5    Matsukage, A.6    Yoshida, S.7    Sakaguchi, K.8
  • 9
    • 0031035303 scopus 로고    scopus 로고
    • In vivo antitumour effect of 3′-sulphonoquinovosyl 1′-monoacylglyceride isolated from sea urchin (Strongylocentrotus intermedius) intestine
    • Sahara H, Ishikawa M, Takahashi N, Ohtani S, Sato N, Gasa S, Akino T & Kikuchi K (1997) In vivo antitumour effect of 3′-sulphonoquinovosyl 1′-monoacylglyceride isolated from sea urchin (Strongylocentrotus intermedius) intestine. Br J Cancer 75, 324-332.
    • (1997) Br J Cancer , vol.75 , pp. 324-332
    • Sahara, H.1    Ishikawa, M.2    Takahashi, N.3    Ohtani, S.4    Sato, N.5    Gasa, S.6    Akino, T.7    Kikuchi, K.8
  • 10
    • 0035834590 scopus 로고    scopus 로고
    • Specific interaction between an oligosaccharide on the tumor cell surface and the novel antitumor agents, sulfoquinovosylacylglycerols
    • Ohta K, Mizushina Y, Yamazaki T, Hanashima S, Sugawara F & Sakaguchi K (2001) Specific interaction between an oligosaccharide on the tumor cell surface and the novel antitumor agents, sulfoquinovosylacylglycerols. Biochem Biophys Res Commun 288, 893-900.
    • (2001) Biochem Biophys Res Commun , vol.288 , pp. 893-900
    • Ohta, K.1    Mizushina, Y.2    Yamazaki, T.3    Hanashima, S.4    Sugawara, F.5    Sakaguchi, K.6
  • 11
    • 0034621392 scopus 로고    scopus 로고
    • Studies on a novel DNA polymerase inhibitor group, synthetic sulfoquinovosylacylglycerols: Inhibitory action on cell proliferation
    • Ohta K, Hanashima S, Mizushina Y, Yamazaki T, Saneyoshi M, Sugawara F & Sakaguchi K (2000) Studies on a novel DNA polymerase inhibitor group, synthetic sulfoquinovosylacylglycerols: inhibitory action on cell proliferation. Mutat Res 467, 139-152.
    • (2000) Mutat Res , vol.467 , pp. 139-152
    • Ohta, K.1    Hanashima, S.2    Mizushina, Y.3    Yamazaki, T.4    Saneyoshi, M.5    Sugawara, F.6    Sakaguchi, K.7
  • 14
    • 0033119535 scopus 로고    scopus 로고
    • DNA polymerase beta-like nucleotidyltransferase superfamily: Identification of three new families, classification and evolutionary history
    • Aravind L & Koonin EV (1999) DNA polymerase beta-like nucleotidyltransferase superfamily: identification of three new families, classification and evolutionary history. Nucleic Acids Res 27, 1609-1618.
    • (1999) Nucleic Acids Res , vol.27 , pp. 1609-1618
    • Aravind, L.1    Koonin, E.V.2
  • 16
    • 0028136070 scopus 로고
    • Crystal structure of rat DNA polymerase beta: Evidence for a common polymerase mechanism
    • Sawaya MR, Pelletier H, Kumar A, Wilson SH & Kraut J (1994) Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism. Science 264, 1930-1935.
    • (1994) Science , vol.264 , pp. 1930-1935
    • Sawaya, M.R.1    Pelletier, H.2    Kumar, A.3    Wilson, S.H.4    Kraut, J.5
  • 17
    • 0034635344 scopus 로고    scopus 로고
    • Backbone dynamics and refined solution structure of the N-terminal domain of DNA polymerase beta. Correlation with DNA binding and dRP lyase activity
    • Maciejewski MW, Liu D, Prasad R, Wilson SH & Mullen GP (2000) Backbone dynamics and refined solution structure of the N-terminal domain of DNA polymerase beta. Correlation with DNA binding and dRP lyase activity. J Mol Biol 296, 229-253.
    • (2000) J Mol Biol , vol.296 , pp. 229-253
    • Maciejewski, M.W.1    Liu, D.2    Prasad, R.3    Wilson, S.H.4    Mullen, G.P.5
  • 18
    • 0030930760 scopus 로고    scopus 로고
    • Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: Evidence for an induced fit mechanism
    • Sawaya MR, Prasad R, Wilson SH, Kraut J & Pelletier H (1997) Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. Biochemistry 36, 11205-11215.
    • (1997) Biochemistry , vol.36 , pp. 11205-11215
    • Sawaya, M.R.1    Prasad, R.2    Wilson, S.H.3    Kraut, J.4    Pelletier, H.5
  • 19
    • 0029817866 scopus 로고    scopus 로고
    • Crystal structures of human DNA polymerase beta complexed with DNA: Implications for catalytic mechanism, processivity, and fidelity
    • Pelletier H, Sawaya MR, Woffle W, Wilson SH & Kraut J (1996) Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity. Biochemistry 35, 12742-12761.
    • (1996) Biochemistry , vol.35 , pp. 12742-12761
    • Pelletier, H.1    Sawaya, M.R.2    Woffle, W.3    Wilson, S.H.4    Kraut, J.5
  • 20
    • 0033520309 scopus 로고    scopus 로고
    • Mode analysis of a fatty acid molecule binding to the N-terminal 8-kDa domain of DNA polymerase beta. A 1:1 complex and binding surface
    • Mizushina Y, Ohkubo T, Date T, Yamaguchi T, Saneyoshi M, Sugawara F & Sakaguchi K (1999) Mode analysis of a fatty acid molecule binding to the N-terminal 8-kDa domain of DNA polymerase beta. A 1:1 complex and binding surface. J Biol Chem 274, 25599-25607.
    • (1999) J Biol Chem , vol.274 , pp. 25599-25607
    • Mizushina, Y.1    Ohkubo, T.2    Date, T.3    Yamaguchi, T.4    Saneyoshi, M.5    Sugawara, F.6    Sakaguchi, K.7
  • 21
    • 0034680359 scopus 로고    scopus 로고
    • Structure of lithocholic acid binding to the N-terminal 8-kDa domain of DNA polymerase beta
    • Mizushina Y, Ohkubo T, Sugawara F & Sakaguchi K (2000) Structure of lithocholic acid binding to the N-terminal 8-kDa domain of DNA polymerase beta. Biochemistry 39, 12606-12613.
    • (2000) Biochemistry , vol.39 , pp. 12606-12613
    • Mizushina, Y.1    Ohkubo, T.2    Sugawara, F.3    Sakaguchi, K.4
  • 22
    • 0033756423 scopus 로고    scopus 로고
    • Structure-activity relationship of a novel group of mammalian DNA polymerase inhibitors, synthetic sulfoquinovosylacylglycerols
    • Hanashima S, Mizushina Y, Ohta K, Yamazaki T, Sugawara F & Sakaguchi K (2000) Structure-activity relationship of a novel group of mammalian DNA polymerase inhibitors, synthetic sulfoquinovosylacylglycerols. Jpn J Cancer Res 91, 1073-1083.
    • (2000) Jpn J Cancer Res , vol.91 , pp. 1073-1083
    • Hanashima, S.1    Mizushina, Y.2    Ohta, K.3    Yamazaki, T.4    Sugawara, F.5    Sakaguchi, K.6
  • 24
    • 0023839680 scopus 로고
    • Expression of human DNA polymerase beta in Escherichia coli and characterization of the recombinant enzyme
    • Abbotts J, SenGupta DN, Zmudzka B, Widen SG, Notario V & Wilson SH (1988) Expression of human DNA polymerase beta in Escherichia coli and characterization of the recombinant enzyme. Biochemistry 27, 901-909.
    • (1988) Biochemistry , vol.27 , pp. 901-909
    • Abbotts, J.1    Sengupta, D.N.2    Zmudzka, B.3    Widen, S.G.4    Notario, V.5    Wilson, S.H.6
  • 26
    • 4344711355 scopus 로고    scopus 로고
    • Theory and applications of NMR-based screening in pharmaceutical research
    • Lepre CA, Moore JM & Peng JW (2004) Theory and applications of NMR-based screening in pharmaceutical research. Chem Rev 104, 3641-3676.
    • (2004) Chem Rev , vol.104 , pp. 3641-3676
    • Lepre, C.A.1    Moore, J.M.2    Peng, J.W.3
  • 27
    • 0042880971 scopus 로고    scopus 로고
    • An empirical approach for structure-based prediction of carbohydrate-binding sites on proteins
    • Shionyu Mitsuyama C, Shirai T, Ishida H & Yamane T (2003) An empirical approach for structure-based prediction of carbohydrate-binding sites on proteins. Protein Eng 16, 467-478.
    • (2003) Protein Eng , vol.16 , pp. 467-478
    • Shionyu Mitsuyama, C.1    Shirai, T.2    Ishida, H.3    Yamane, T.4
  • 28
    • 0032080334 scopus 로고    scopus 로고
    • Functional analysis of the amino-terminal 8-kDa domain of DNA polymerase beta as revealed by site-directed mutagenesis. DNA binding and 5′-deoxyribose phosphate lyase activities
    • Prasad R, Beard WA, Chyan JY, Maciejewski MW, Mullen GP & Wilson SH (1998) Functional analysis of the amino-terminal 8-kDa domain of DNA polymerase beta as revealed by site-directed mutagenesis. DNA binding and 5′-deoxyribose phosphate lyase activities. J Biol Chem 273, 11121-11126.
    • (1998) J Biol Chem , vol.273 , pp. 11121-11126
    • Prasad, R.1    Beard, W.A.2    Chyan, J.Y.3    Maciejewski, M.W.4    Mullen, G.P.5    Wilson, S.H.6
  • 31
    • 0026002415 scopus 로고
    • Spectroscopic studies of the structural domains of mammalian DNA beta-polymerase
    • Casas Finet JR, Kumar A, Morris G, Wilson SH & Karpel RL (1991) Spectroscopic studies of the structural domains of mammalian DNA beta-polymerase. J Biol Chem 266, 19618-19625.
    • (1991) J Biol Chem , vol.266 , pp. 19618-19625
    • Casas Finet, J.R.1    Kumar, A.2    Morris, G.3    Wilson, S.H.4    Karpel, R.L.5
  • 32
    • 0020410237 scopus 로고
    • Studies on the mechanism of Escherichia coli DNA polymerase I large fragment. Chain termination and modulation by polynucleotides
    • Detera SD & Wilson SH (1982) Studies on the mechanism of Escherichia coli DNA polymerase I large fragment. Chain termination and modulation by polynucleotides. J Biol Chem 257, 9770-9780.
    • (1982) J Biol Chem , vol.257 , pp. 9770-9780
    • Detera, S.D.1    Wilson, S.H.2
  • 35
    • 0000041361 scopus 로고
    • A common sense approach to peak picking two-, three- and four-dimensional spectra using automatic computer analysis of contour diagrams
    • Garrett DS, Powers R, Gronenborn AM & Clore GM (1991) A common sense approach to peak picking two-, three- and four-dimensional spectra using automatic computer analysis of contour diagrams. J Magn Reson 95, 214-220.
    • (1991) J Magn Reson , vol.95 , pp. 214-220
    • Garrett, D.S.1    Powers, R.2    Gronenborn, A.M.3    Clore, G.M.4
  • 37
    • 0002761710 scopus 로고
    • Isothermal titration calorimetry
    • Freire E, Mayorga OL & Straume M (1990) Isothermal titration calorimetry. Anal Chem 10, 2359-2367.
    • (1990) Anal Chem , vol.10 , pp. 2359-2367
    • Freire, E.1    Mayorga, O.L.2    Straume, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.