A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(α-D-sulfoquinovosyl)-glyceride with stearic acid

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1645, Issue 1, 2003, Pages 72-80

  Murakami, Chikako ^a   Yamazaki, Takayuki ^b   Hanashima, Shinya ^b   Takahashi, Shunya ^c   Takemura, Masaharu ^d   Yoshida, Shonen ^d   Ohta, Keisuke ^b   Yoshida, Hiromi ^a   Sugawara, Fumio ^b   Sakaguchi, Kengo ^b   Mizushina, Yoshiyuki ^a  

^a KOBE GAKUIN UNIVERSITY   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

^c INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^d NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

SQMG C18 ( sulfoquinovosyl monoacylglycerol with a stearic acid molecule); SQDG (sulfoquinovosyl diacylglycerol); SQMG (sulfoquinovosyl monoacylglycerol); Sulfo glycolipid

Indexed keywords

2 MONO O ACYL 3 O (ALPHA DEXTRO SULFOQUINOVOSYL)GLYCERIDE; ACYLGLYCEROL; ANTINEOPLASTIC AGENT; CYCLIN E; DNA POLYMERASE; PROTEIN P53; STEARIC ACID; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; 2 STEAROYL 3 O SULFOQUINOVOSYLGLYCERIDE; 2-STEAROYL-3-O-SULFOQUINOVOSYLGLYCERIDE; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE BETA; ENZYME INHIBITOR; GLYCOLIPID; STEARIC ACID DERIVATIVE;

APOPTOSIS; ARTICLE; CANCER GROWTH; CELL CYCLE G1 PHASE; CELL STRAIN; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG PENETRATION; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HYDROLYSIS; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; CELL CULTURE; CELL CYCLE; CELL MEMBRANE PERMEABILITY; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; SYNTHESIS;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL MEMBRANE PERMEABILITY; CYCLIN E; DNA POLYMERASE I; DNA-DIRECTED DNA POLYMERASE; ENZYME INHIBITORS; GLYCOLIPIDS; HUMANS; LIPASE; MOLECULAR STRUCTURE; STEARIC ACIDS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0037474191     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-9639(02)00521-6     Document Type: Article

References (36)

1. Yoshida S., Yamada M., Masaki S. Biochim. Biophys. Acta. 477:1977;144-150.
2. Yarchoan R., Mitsuya H., Myers C.E., Broder S. N. Engl. J. Med. 321:1989;726-738.
3. Matsumoto Y., Sahara H., Fujita T., Hanashima S., Yamazaki T., Takahashi S., Sugawara F., Mizushina Y., Ohta K., Takahashi N., Jimbow K., Sakaguchi K., Sato N. Transplant. Proc. 32:2000;2051-2053.
4. Sahara H., Hanashima S., Yamazaki T., Takahashi S., Sugawara F., Ohtani S., Ishikawa M., Mizushina Y., Ohta K., Shimozawa K., Gasa S., Jimbow K., Sakaguchi K., Sato N., Takahashi N. Jpn. J. Cancer Res. 93:2002;85-92.
5. Hanashima S., Mizushina Y., Ohta K., Yamazaki T., Sugawara F., Sakaguchi K. Jpn. J. Cancer Res. 91:2000;1073-1083.
6. Hanashima S., Mizushina Y., Yamazaki T., Ohta K., Takahashi S., Koshino H., Sahara H., Sakaguchi K., Sugawara F. Tetrahedron Lett. 41:2000;4403-4407.
7. Hanashima S., Mizushina Y., Yamazaki T., Ohta K., Takahashi S., Sahara H., Sakaguchi K., Sugawara F. Bioorg. Med. Chem. 9:2001;367-376.
8. Mizushina Y., Watanabe I., Ohta K., Takemura M., Sahara H., Takahashi N., Gasa S., Sugawara F., Matsukage A., Yoshida S., Sakaguchi K. Biochem. Pharmacol. 55:1998;537-541.
9. Ohta K., Mizushina Y., Hirata N., Takemura M., Sugawara F., Matsukage A., Yoshida S., Sakaguchi K. Chem. Pharm. Bull. 46:1998;684-686.
10. Ohta K., Mizushina Y., Hirata N., Takemura M., Sugawara F., Matsukage A., Yoshida S., Sakaguchi K. Biol. Pharm. Bull. 22:1999;111-116.
11. Mudd J.B., Kleppinger-Sparace K.F. Stumph K.P. The Biochemistry of Plants. 1987;275-289 Academic Press, London.
12. Benning C. Annu. Rev. Plant Physiol. Plant Mol. Biol. 48:1998;53-75.
13. Gustafson K.R., Cardellina J.H. II, Fuller R.W., Weislo O.S., Kiser R.F., Snader K.M., Patterson G.M.L., Boyd M.R. J. Natl. Cancer Inst. 81:1989;1254-1258.
14. Yoshida H., Alexander J.C. Lipids. 18:1983;402-407.
15. Tamai K., Kojima K., Hanaichi T., Masaki S., Suzuki M., Umekawa H., Yoshida S. Biochim. Biophys. Acta. 950:1988;263-273.
16. Date T., Yamaguchi M., Hirose F., Nishimoto Y., Tanihara K., Matsukage A. Biochemistry. 27:1988;2983-2990.
17. Mizushina Y., Tanaka N., Yagi H., Kurosawa T., Onoue M., Seto H., Horie T., Aoyagi N., Yamaoka M., Matsukage A., Yoshida S., Sakaguchi K. Biochim. Biophys. Acta. 1308:1996;256-262.
18. Mizushina Y., Yoshida S., Matsukage A., Sakaguchi K. Biochim. Biophys. Acta. 1336:1997;509-521.
19. Roughan P.G., Batt R.D. Phytochemistry. 8:1969;363-369.
20. Kornberg A., Baker T.A. 2nd ed. DNA Replication. vol. 6:1992;197-225 Freeman, New York.
21. Kaufmann S.H. Biochim. Biophys. Acta. 1400:1998;195-211.
22. Moreland N.J., Illand M., Kim Y.T., Paul J., Brown R. Cancer Res. 59:1999;2102-2106.
23. Sherr C.J. Science. 274:1996;1672-1677.
24. Dulic V., Lees E., Reed S.I. Science. 257:1992;1958-1961.
25. Koff A., Giordano A., Desai D., Katsumi Y., Happer J.W., Elledge S., Nishimoto T., Morgan D.O., Franza B.R., Robert J.M. Science. 257:1992;1689-1694.
26. Hartwell L.H., Kastan M.B. Science. 266:1994;1821-1828.
27. Kastan M.B., Zhan Q., el-Deiry W.S., Carrier F., Jacks T., Walsh W.V., Plunkett B.S., Vogelstein B., Fornace A.J. Jr. Cell. 71:1992;587-597.
28. Kuberbitz S.J., Plunkett B.S., Walsh W.V., Kasstan M.B. Proc. Natl. Acad. Sci. U. S. A. 89:1992;7491-7495.
29. Allan L.A., Fried M. Oncogene. 18:1999;5403-5412.
30. Lowe S.W., Schmitt E.M., Smith S.W., Osborne B.A., Jack T. Nature. 362:1993;847-849.
31. Dou Q.P., An B., Yu C. Biochem. Biophys. Res. Commun. 214:1995;771-780.
32. Dou Q.P., An B., Will P. Proc. Natl. Acad. Sci. U. S. A. 92:1995;9019-9023.
33. Livingstone L.R., White A., Sprouse J., Livanos E., Jack T., Tlsty T.D. Cell. 70:1992;923-935.
34. Yin Y., Tainsky M.A., Bischoff F.Z., Strong L.C., Wahl G.M. Cell. 70:1992;937-948.
35. Pastorino J.G., Chen S.T., Tafani M., Snyder J.W., Farber J.L. J. Biol. Chem. 273:1998;7770-7775.
36. Granvile D.J., Carthy C.M., Hunt D.W.C., McManus B.M. Lab. Invest. 78:1998;893-913.