Mismatch repair deficient human cells: Spontaneous and MNNG-induced mutational spectra in the HPRT gene

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 450, Issue 1-2, 2000, Pages 125-138

  Tomita Mitchell, Aoy ^a   Kat, Alexandra G ^a   Marcelino, Luisa A ^a   Li Sucholeiki, Xiao Cheng ^a   Goodluck Griffith, Jacklene ^a   Thilly, William G ^a  

^a Massachusetts Institute of Technology   (United States)

Author keywords

Alkylation; CDCE; DGGE; High fidelity PCR; hMSH6; Methylation; Mismatch repair; Mutational spectrum

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MESSENGER RNA; METHYLNITRONITROSOGUANIDINE; MUTAGENIC AGENT;

BASE MISPAIRING; CAPILLARY ELECTROPHORESIS; CELL LINE; CONTROLLED STUDY; DENATURING GRADIENT GEL ELECTROPHORESIS; DNA FLANKING REGION; DNA METHYLATION; DNA REPAIR; EXON; GENE MUTATION; HUMAN; HUMAN CELL; INTRON; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVIEW;

ALKYLATING AGENTS; BASE PAIR MISMATCH; BASE SEQUENCE; CELL LINE; DNA PRIMERS; DNA REPAIR; DNA-BINDING PROTEINS; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; METHYLNITRONITROSOGUANIDINE; MUTATION; POLYMERASE CHAIN REACTION;

EID: 0034733020     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(00)00020-8     Document Type: Article

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