The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3

BMC Structural Biology

Volumn 7, Issue , 2007, Pages

  Casares, Salvador ^a   Ab, Eiso ^b   Eshuis, Henk ^b   Lopez Mayorga, Obdulio ^a   Van Nuland, Nico A J ^a   Conejero Lara, Francisco ^a  

^a Instituto de Biotecnologia   (Spain)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ABELSON KINASE; ALANINE; ARGININE; DEUTERIUM; FODRIN; HYDROGEN; PROTEIN SH3; MUTANT PROTEIN; PEPTIDE; SPECTRIN; WATER;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; DIFFERENTIAL SCANNING CALORIMETRY; ENERGY TRANSFER; ENTHALPY; ENTROPY; IMAGE QUALITY; ISOTHERMAL TITRATION CALORIMETRY; LIGAND BINDING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PREDICTION; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; THERMODYNAMICS; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CHICKEN; COMPARATIVE STUDY; GENETICS; METABOLISM; PROTEIN BINDING; SRC HOMOLOGY DOMAIN;

ALANINE; ANIMALS; ARGININE; CALORIMETRY, DIFFERENTIAL SCANNING; CHICKENS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MUTANT PROTEINS; PEPTIDES; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-ABL; SPECTRIN; SRC HOMOLOGY DOMAINS; THERMODYNAMICS; WATER;

EID: 34247385124     PISSN: None     EISSN: 14726807     Source Type: Journal    
DOI: 10.1186/1472-6807-7-22     Document Type: Article

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