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Volumn 109, Issue 9, 2007, Pages 3679-3686

Involvement of Fyn kinase in Kit and integrin-mediated Rac activation, cytoskeletal reorganization, and chemotaxis of mast cells

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; F ACTIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE FYN; RAC PROTEIN; RAC2 PROTEIN; STEM CELL FACTOR;

EID: 34247380314     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-11-057315     Document Type: Article
Times cited : (59)

References (70)
  • 1
    • 33846086541 scopus 로고    scopus 로고
    • New and emerging roles for mast cells in host defence
    • Dawicki W, Marshall JS. New and emerging roles for mast cells in host defence. Curr Opin Immunol. 2007;19:31-38.
    • (2007) Curr Opin Immunol , vol.19 , pp. 31-38
    • Dawicki, W.1    Marshall, J.S.2
  • 2
    • 33646911541 scopus 로고    scopus 로고
    • Mast cells: Ontogeny, homing, and recruitment of a unique innate effector cell
    • Gurish MF, Boyce JA. Mast cells: ontogeny, homing, and recruitment of a unique innate effector cell. J Allergy Clin Immunol. 2006;117:1285-1291.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 1285-1291
    • Gurish, M.F.1    Boyce, J.A.2
  • 3
    • 0023694835 scopus 로고
    • The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus
    • Chabot B, Stephenson DA, Chapman VM, Besmer P, Bernstein A. The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus. Nature. 1988;335:88-89.
    • (1988) Nature , vol.335 , pp. 88-89
    • Chabot, B.1    Stephenson, D.A.2    Chapman, V.M.3    Besmer, P.4    Bernstein, A.5
  • 4
    • 0024280901 scopus 로고
    • The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene
    • Geissler EN, Ryan MA, Housman DE. The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene. Cell. 1988;55:185-192.
    • (1988) Cell , vol.55 , pp. 185-192
    • Geissler, E.N.1    Ryan, M.A.2    Housman, D.E.3
  • 5
    • 33749618623 scopus 로고    scopus 로고
    • Signaling pathways influencing SLF and c-kit-mediated survival and proliferation
    • Berger SA. Signaling pathways influencing SLF and c-kit-mediated survival and proliferation. Immunol Res. 2006;35:1-12.
    • (2006) Immunol Res , vol.35 , pp. 1-12
    • Berger, S.A.1
  • 6
    • 33644752698 scopus 로고    scopus 로고
    • Stem cell factor and its receptor c-Kit as targets for inflammatory diseases
    • Reber L, Da Silva CA, Frossard N. Stem cell factor and its receptor c-Kit as targets for inflammatory diseases. Eur J Pharmacol. 2006;533:327-340.
    • (2006) Eur J Pharmacol , vol.533 , pp. 327-340
    • Reber, L.1    Da Silva, C.A.2    Frossard, N.3
  • 7
    • 12144257058 scopus 로고    scopus 로고
    • Kit as a human oncogenic tyrosine kinase
    • Kitamura Y, Hirotab S. Kit as a human oncogenic tyrosine kinase. Cell Mol Life Sci. 2004;61:2924-2931.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 2924-2931
    • Kitamura, Y.1    Hirotab, S.2
  • 8
    • 0037106370 scopus 로고    scopus 로고
    • Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors
    • Singer S, Rubin BP, Lux ML, et al. Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors. J Clin Oncol. 2002;20:3898-3905.
    • (2002) J Clin Oncol , vol.20 , pp. 3898-3905
    • Singer, S.1    Rubin, B.P.2    Lux, M.L.3
  • 9
    • 33645092405 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumours: An update
    • Rubin BP. Gastrointestinal stromal tumours: an update. Histopathology. 2006;48:83-96.
    • (2006) Histopathology , vol.48 , pp. 83-96
    • Rubin, B.P.1
  • 10
    • 25844507795 scopus 로고    scopus 로고
    • Signaling by Kit protein-tyrosine kinase - the stem cell factor receptor
    • Roskoski R Jr. Signaling by Kit protein-tyrosine kinase - the stem cell factor receptor. Biochem Biophys Res Commun. 2005;337:1-13.
    • (2005) Biochem Biophys Res Commun , vol.337 , pp. 1-13
    • Roskoski Jr., R.1
  • 11
    • 0032476674 scopus 로고    scopus 로고
    • Kit signaling through PI 3-kinase and Src kinase pathways: An essential role for Rac1 and JNK activation in mast cell proliferation
    • Timokhina I, Kissel H, Stella G, Besmer P. Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation. EMBO J. 1998;17:6250-6262.
    • (1998) EMBO J , vol.17 , pp. 6250-6262
    • Timokhina, I.1    Kissel, H.2    Stella, G.3    Besmer, P.4
  • 12
    • 1642458352 scopus 로고    scopus 로고
    • c-Kit-mediated overlapping and unique functional and biochemical outcomes via diverse signaling pathways
    • Hong L, Munugalavadla V, Kapur R. c-Kit-mediated overlapping and unique functional and biochemical outcomes via diverse signaling pathways. Mol Cell Biol. 2004;24:1401-1410.
    • (2004) Mol Cell Biol , vol.24 , pp. 1401-1410
    • Hong, L.1    Munugalavadla, V.2    Kapur, R.3
  • 13
    • 0036566548 scopus 로고    scopus 로고
    • Critical roles of c-Kit tyrosine residues 567 and 719 in stem cell factor-induced chemotaxis: Contribution of src family kinase and PI3- kinase on calcium mobilization and cell migration
    • Ueda S, Mizuki M, Ikeda H, et al. Critical roles of c-Kit tyrosine residues 567 and 719 in stem cell factor-induced chemotaxis: contribution of src family kinase and PI3- kinase on calcium mobilization and cell migration. Blood. 2002;99:3342-3349.
    • (2002) Blood , vol.99 , pp. 3342-3349
    • Ueda, S.1    Mizuki, M.2    Ikeda, H.3
  • 14
    • 0031048834 scopus 로고    scopus 로고
    • Direct association of Csk homologous kinase (CHK) with the diphosphorylated site Tyr568/570 of the activated c-KIT in megakaryocytes
    • Price DJ, Rivnay B, Fu Y, Jiang S, Avraham S, Avraham H. Direct association of Csk homologous kinase (CHK) with the diphosphorylated site Tyr568/570 of the activated c-KIT in megakaryocytes. J Biol Chem. 1997;272:5915-5920.
    • (1997) J Biol Chem , vol.272 , pp. 5915-5920
    • Price, D.J.1    Rivnay, B.2    Fu, Y.3    Jiang, S.4    Avraham, S.5    Avraham, H.6
  • 15
    • 33749376770 scopus 로고    scopus 로고
    • The scaffolding adapter Gab2, via Shp-2, regulates kit-evoked mast cell proliferation by activating the Rac/JNK pathway
    • Yu M, Luo J, Yang W, et al. The scaffolding adapter Gab2, via Shp-2, regulates kit-evoked mast cell proliferation by activating the Rac/JNK pathway. J Biol Chem. 2006;281:28615-28626.
    • (2006) J Biol Chem , vol.281 , pp. 28615-28626
    • Yu, M.1    Luo, J.2    Yang, W.3
  • 16
    • 0035880224 scopus 로고    scopus 로고
    • Lyn is required for normal stem cell factor-induced proliferation and chemotaxis of primary hematopoietic cells
    • O'Laughlin-Bunner B, Radosevic N, Taylor ML, et al. Lyn is required for normal stem cell factor-induced proliferation and chemotaxis of primary hematopoietic cells. Blood. 2001;98:343-350.
    • (2001) Blood , vol.98 , pp. 343-350
    • O'Laughlin-Bunner, B.1    Radosevic, N.2    Taylor, M.L.3
  • 17
    • 1942533518 scopus 로고    scopus 로고
    • Targeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineages
    • Kimura Y, Jones N, Kluppel M, et al. Targeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineages. Proc Natl Acad Sci U S A. 2004;101:6015-6020.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 6015-6020
    • Kimura, Y.1    Jones, N.2    Kluppel, M.3
  • 18
    • 2942659761 scopus 로고    scopus 로고
    • Negative regulation of immunoglobulin E-dependent allergic responses by Lyn kinase
    • Odom S, Gomez G, Kovarova M, et al. Negative regulation of immunoglobulin E-dependent allergic responses by Lyn kinase. J Exp Med. 2004;199:1491-1502.
    • (2004) J Exp Med , vol.199 , pp. 1491-1502
    • Odom, S.1    Gomez, G.2    Kovarova, M.3
  • 19
    • 0038771965 scopus 로고    scopus 로고
    • The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
    • Neel BG, Gu H, Pao L. The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem Sci. 2003;28:284-293.
    • (2003) Trends Biochem Sci , vol.28 , pp. 284-293
    • Neel, B.G.1    Gu, H.2    Pao, L.3
  • 20
    • 33749376770 scopus 로고    scopus 로고
    • The scaffolding adapter gab2, via SHP-2, regulates kit-evoked mast cell proliferation by activating the Rac/JNK pathway
    • Yu M, Luo J, Yang W, et al. The scaffolding adapter gab2, via SHP-2, regulates kit-evoked mast cell proliferation by activating the Rac/JNK pathway. J Biol Chem. 2006;281:28615-28626.
    • (2006) J Biol Chem , vol.281 , pp. 28615-28626
    • Yu, M.1    Luo, J.2    Yang, W.3
  • 21
    • 22244480680 scopus 로고    scopus 로고
    • Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane
    • Nishida K, Yamasaki S, Ito Y, et al. Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane. J Cell Biol. 2005;170:115-126.
    • (2005) J Cell Biol , vol.170 , pp. 115-126
    • Nishida, K.1    Yamasaki, S.2    Ito, Y.3
  • 22
    • 0036347746 scopus 로고    scopus 로고
    • Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation
    • Parravicini V, Gadina M, Kovarova M, et al. Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation. Nat Immunol. 2002;3:741-748.
    • (2002) Nat Immunol , vol.3 , pp. 741-748
    • Parravicini, V.1    Gadina, M.2    Kovarova, M.3
  • 23
    • 32044474897 scopus 로고    scopus 로고
    • Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcepsilonRI
    • Yu M, Lowell CA, Neel BG, Gu H. Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcepsilonRI. J Immunol. 2006;176:2421-2429.
    • (2006) J Immunol , vol.176 , pp. 2421-2429
    • Yu, M.1    Lowell, C.A.2    Neel, B.G.3    Gu, H.4
  • 24
    • 0037129193 scopus 로고    scopus 로고
    • SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling
    • Shinohara M, Terada Y, Iwamatsu A, et al. SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling. Nature. 2002;416:759-763.
    • (2002) Nature , vol.416 , pp. 759-763
    • Shinohara, M.1    Terada, Y.2    Iwamatsu, A.3
  • 25
    • 8644258378 scopus 로고    scopus 로고
    • SWAP-70 regulates c-kit-induced mast cell activation, cell-cell adhesion, and migration
    • Sivalenka RR, Jessberger R. SWAP-70 regulates c-kit-induced mast cell activation, cell-cell adhesion, and migration. Mol Cell Biol. 2004;24:10277-10288.
    • (2004) Mol Cell Biol , vol.24 , pp. 10277-10288
    • Sivalenka, R.R.1    Jessberger, R.2
  • 26
    • 33644983002 scopus 로고    scopus 로고
    • Direct binding of SWAP-70 to non-muscle actin is required for membrane ruffling
    • Ihara S, Oka T, Fukui Y. Direct binding of SWAP-70 to non-muscle actin is required for membrane ruffling. J Cell Sci. 2006;119:500-507.
    • (2006) J Cell Sci , vol.119 , pp. 500-507
    • Ihara, S.1    Oka, T.2    Fukui, Y.3
  • 27
    • 0038792208 scopus 로고    scopus 로고
    • Genetic evidence for convergence of c-Kit- and alpha4 integrin-mediated signals on class IA PI-3kinase and the Rac pathway in regulating integrin-directed migration in mast cells
    • Tan BL, Yazicioglu MN, Ingram D, et al. Genetic evidence for convergence of c-Kit- and alpha4 integrin-mediated signals on class IA PI-3kinase and the Rac pathway in regulating integrin-directed migration in mast cells. Blood. 2003;101:4725-4732.
    • (2003) Blood , vol.101 , pp. 4725-4732
    • Tan, B.L.1    Yazicioglu, M.N.2    Ingram, D.3
  • 28
    • 0035313462 scopus 로고    scopus 로고
    • Cross-talk between alpha(4)beta(1)/alpha(5)beta(1) and c-Kit results in opposing effect on growth and survival of hematopoietic cells via the activation of focal adhesion kinase, mitogen-activated protein kinase, and Akt signaling pathways
    • Kapur R, Cooper R, Zhang L, Williams DA. Cross-talk between alpha(4)beta(1)/alpha(5)beta(1) and c-Kit results in opposing effect on growth and survival of hematopoietic cells via the activation of focal adhesion kinase, mitogen-activated protein kinase, and Akt signaling pathways. Blood. 2001;97:1975-1981.
    • (2001) Blood , vol.97 , pp. 1975-1981
    • Kapur, R.1    Cooper, R.2    Zhang, L.3    Williams, D.A.4
  • 29
    • 0038162476 scopus 로고    scopus 로고
    • Leukocyte uropod formation and membrane/cytoskeleton linkage in immune interactions
    • Fais S, Malorni W. Leukocyte uropod formation and membrane/cytoskeleton linkage in immune interactions. J Leukoc Biol. 2003;73:556-563.
    • (2003) J Leukoc Biol , vol.73 , pp. 556-563
    • Fais, S.1    Malorni, W.2
  • 30
    • 27844604200 scopus 로고    scopus 로고
    • GTPases and the control of cell behaviour
    • Hall A. Rho GTPases and the control of cell behaviour. Biochem Soc Trans. 2005;33:891-895.
    • (2005) Biochem Soc Trans , vol.33 , pp. 891-895
    • Rho, H.A.1
  • 31
    • 0024425981 scopus 로고    scopus 로고
    • Didsbury J, Weber RF, Bokoch GM, Evans T, Snyderman R. rac, a novel ras-related family of proteins that are botulinum toxin substrates. J Biol Chem. 1989;264:16378-16382.
    • Didsbury J, Weber RF, Bokoch GM, Evans T, Snyderman R. rac, a novel ras-related family of proteins that are botulinum toxin substrates. J Biol Chem. 1989;264:16378-16382.
  • 32
    • 0036720830 scopus 로고    scopus 로고
    • The TRQQKRP motif located near the C-terminus of Rac2 is essential for Rac2 biologic functions and intracellular localization
    • Tao W, Filippi MD, Bailey JR, et al. The TRQQKRP motif located near the C-terminus of Rac2 is essential for Rac2 biologic functions and intracellular localization. Blood. 2002;100:1679-1688.
    • (2002) Blood , vol.100 , pp. 1679-1688
    • Tao, W.1    Filippi, M.D.2    Bailey, J.R.3
  • 33
    • 0035989343 scopus 로고    scopus 로고
    • Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in T(H)1 responses
    • Croker BA, Handman E, Hayball JD, et al. Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in T(H)1 responses. Immunol Cell Biol. 2002;80:231-240.
    • (2002) Immunol Cell Biol , vol.80 , pp. 231-240
    • Croker, B.A.1    Handman, E.2    Hayball, J.D.3
  • 34
    • 0036533662 scopus 로고    scopus 로고
    • The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes
    • Croker BA, Tarlinton DM, Cluse LA, et al. The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes. J Immunol. 2002;168:3376-3386.
    • (2002) J Immunol , vol.168 , pp. 3376-3386
    • Croker, B.A.1    Tarlinton, D.M.2    Cluse, L.A.3
  • 35
    • 0035826843 scopus 로고    scopus 로고
    • Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization
    • Yang FC, Atkinson SJ, Gu Y, et al. Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization. Proc Natl Acad Sci U S A. 2001;98:5614-5618.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5614-5618
    • Yang, F.C.1    Atkinson, S.J.2    Gu, Y.3
  • 36
    • 0033678937 scopus 로고    scopus 로고
    • Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells
    • Yang FC, Kapur R, King AJ, et al. Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells. Immunity. 2000;12:557-568.
    • (2000) Immunity , vol.12 , pp. 557-568
    • Yang, F.C.1    Kapur, R.2    King, A.J.3
  • 37
    • 0036837891 scopus 로고    scopus 로고
    • Rac2, a hematopoiesis-specific Rho GTPase, specifically regulates mast cell protease gene expression in bone marrow-derived mast cells
    • Gu Y, Byrne MC, Paranavitana NC, et al. Rac2, a hematopoiesis-specific Rho GTPase, specifically regulates mast cell protease gene expression in bone marrow-derived mast cells. Mol Cell Biol. 2002;22:7645-7657.
    • (2002) Mol Cell Biol , vol.22 , pp. 7645-7657
    • Gu, Y.1    Byrne, M.C.2    Paranavitana, N.C.3
  • 38
    • 0026612411 scopus 로고
    • pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells
    • Stein PL, Lee HM, Rich S, Soriano P. pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell. 1992;70:741-750.
    • (1992) Cell , vol.70 , pp. 741-750
    • Stein, P.L.1    Lee, H.M.2    Rich, S.3    Soriano, P.4
  • 39
    • 0028385758 scopus 로고
    • Versatile retroviral vectors for potential use in gene therapy
    • Hawley RG, Lieu FH, Fong AZ, Hawley TS. Versatile retroviral vectors for potential use in gene therapy. Gene Ther. 1994;1:136-138.
    • (1994) Gene Ther , vol.1 , pp. 136-138
    • Hawley, R.G.1    Lieu, F.H.2    Fong, A.Z.3    Hawley, T.S.4
  • 40
    • 33744827154 scopus 로고    scopus 로고
    • Fyn kinase acts upstream of Shp2 and p38 mitogen-activated protein kinase to promote chemotaxis of mast cells towards stem cell factor
    • Samayawardhena LA, Hu J, Stein PL, Craig AW. Fyn kinase acts upstream of Shp2 and p38 mitogen-activated protein kinase to promote chemotaxis of mast cells towards stem cell factor. Cell Signal. 2006;18:1447-1454.
    • (2006) Cell Signal , vol.18 , pp. 1447-1454
    • Samayawardhena, L.A.1    Hu, J.2    Stein, P.L.3    Craig, A.W.4
  • 41
    • 0033013866 scopus 로고    scopus 로고
    • Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor
    • Wennstrom S, Downward J. Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor. Mol Cell Biol. 1999;19:4279-4288.
    • (1999) Mol Cell Biol , vol.19 , pp. 4279-4288
    • Wennstrom, S.1    Downward, J.2
  • 42
    • 0036724531 scopus 로고    scopus 로고
    • Fer kinase is required for sustained p38 MAP kinase activation and maximal chemotaxis of activated mast cells
    • Craig A, Greer P. Fer kinase is required for sustained p38 MAP kinase activation and maximal chemotaxis of activated mast cells. Mol Cell Biol. 2002;22:6363-6374.
    • (2002) Mol Cell Biol , vol.22 , pp. 6363-6374
    • Craig, A.1    Greer, P.2
  • 43
    • 33744827154 scopus 로고    scopus 로고
    • Fyn kinase acts upstream of Shp2 and p38 mitogen-activated protein kinase to promote chemotaxis of mast cells towards stem cell factor
    • Samayawardhena LA, Hu J, Stein PL, Craig AW. Fyn kinase acts upstream of Shp2 and p38 mitogen-activated protein kinase to promote chemotaxis of mast cells towards stem cell factor. Cell Signal. 2006;18:1447-1454.
    • (2006) Cell Signal , vol.18 , pp. 1447-1454
    • Samayawardhena, L.A.1    Hu, J.2    Stein, P.L.3    Craig, A.W.4
  • 44
    • 33646340969 scopus 로고    scopus 로고
    • IgE-dependent activation of sphingosine kinases 1 and 2 and secretion of sphingosine 1-phosphate requires Fyn kinase and contributes to mast cell responses
    • Olivera A, Urtz N, Mizugishi K, et al. IgE-dependent activation of sphingosine kinases 1 and 2 and secretion of sphingosine 1-phosphate requires Fyn kinase and contributes to mast cell responses. J Biol Chem. 2006;281:2515-2525.
    • (2006) J Biol Chem , vol.281 , pp. 2515-2525
    • Olivera, A.1    Urtz, N.2    Mizugishi, K.3
  • 45
    • 27744592100 scopus 로고    scopus 로고
    • Positive and negative regulation of mast cell activation by Lyn via the FcepsilonRI
    • Xiao W, Nishimoto H, Hong H, et al. Positive and negative regulation of mast cell activation by Lyn via the FcepsilonRI. J Immunol. 2005;175:6885-6892.
    • (2005) J Immunol , vol.175 , pp. 6885-6892
    • Xiao, W.1    Nishimoto, H.2    Hong, H.3
  • 46
    • 33344470236 scopus 로고    scopus 로고
    • Integrated signalling pathways for mast-cell activation
    • Gilfillan AM, Tkaczyk C. Integrated signalling pathways for mast-cell activation. Nat Rev Immunol. 2006;6:218-230.
    • (2006) Nat Rev Immunol , vol.6 , pp. 218-230
    • Gilfillan, A.M.1    Tkaczyk, C.2
  • 47
    • 0036566548 scopus 로고    scopus 로고
    • Critical roles of c-Kit tyrosine residues 567 and 719 in stem cell factor-induced chemotaxis: Contribution of src family kinase and PI3-kinase on calcium mobilization and cell migration
    • Ueda S, Mizuki M, Ikeda H, et al. Critical roles of c-Kit tyrosine residues 567 and 719 in stem cell factor-induced chemotaxis: contribution of src family kinase and PI3-kinase on calcium mobilization and cell migration. Blood. 2002;99:3342-3349.
    • (2002) Blood , vol.99 , pp. 3342-3349
    • Ueda, S.1    Mizuki, M.2    Ikeda, H.3
  • 48
    • 0141865507 scopus 로고    scopus 로고
    • Force-dependent integrin-cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2
    • von Wichert G, Haimovich B, Feng GS, Sheetz MP. Force-dependent integrin-cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2. EMBO J. 2003;22:5023-5035.
    • (2003) EMBO J , vol.22 , pp. 5023-5035
    • von Wichert, G.1    Haimovich, B.2    Feng, G.S.3    Sheetz, M.P.4
  • 49
    • 33744772918 scopus 로고    scopus 로고
    • Fibronectin rigidity response through Fyn and p130Cas recruitment to the leading edge
    • Kostic A, Sheetz MP. Fibronectin rigidity response through Fyn and p130Cas recruitment to the leading edge. Mol Biol Cell. 2006;17:2684-2695.
    • (2006) Mol Biol Cell , vol.17 , pp. 2684-2695
    • Kostic, A.1    Sheetz, M.P.2
  • 50
    • 33744956948 scopus 로고    scopus 로고
    • Integrin-induced tyrosine phosphorylation of protein-tyrosine phosphatase-alpha is required for cytoskeletal reorganization and cell migration
    • Chen M, Chen SC, Pallen CJ. Integrin-induced tyrosine phosphorylation of protein-tyrosine phosphatase-alpha is required for cytoskeletal reorganization and cell migration. J Biol Chem. 2006;281:11972-11980.
    • (2006) J Biol Chem , vol.281 , pp. 11972-11980
    • Chen, M.1    Chen, S.C.2    Pallen, C.J.3
  • 51
    • 33645889655 scopus 로고    scopus 로고
    • Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways
    • Giannone G, Sheetz MP. Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways. Trends Cell Biol. 2006;16:213-223.
    • (2006) Trends Cell Biol , vol.16 , pp. 213-223
    • Giannone, G.1    Sheetz, M.P.2
  • 52
    • 0033587177 scopus 로고    scopus 로고
    • Targeted disruption of the tyrosine phosphatase PTP-alpha leads to constitutive downregulation of the kinases Src and Fyn
    • Ponniah S, Wang DZ, Lim KL, Pallen CJ. Targeted disruption of the tyrosine phosphatase PTP-alpha leads to constitutive downregulation of the kinases Src and Fyn. Curr Biol. 1999;9:535-538.
    • (1999) Curr Biol , vol.9 , pp. 535-538
    • Ponniah, S.1    Wang, D.Z.2    Lim, K.L.3    Pallen, C.J.4
  • 53
    • 0026705734 scopus 로고
    • Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase
    • Zheng XM, Wang Y, Pallen CJ. Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase. Nature. 1992;359:336-339.
    • (1992) Nature , vol.359 , pp. 336-339
    • Zheng, X.M.1    Wang, Y.2    Pallen, C.J.3
  • 54
    • 27144513427 scopus 로고    scopus 로고
    • Integrin alpha4beta1 promotes focal adhesion kinase-independent cell motility via alpha4 cytoplasmic domain-specific activation of c-Src
    • Hsia DA, Lim ST, Bernard-Trifilo JA, et al. Integrin alpha4beta1 promotes focal adhesion kinase-independent cell motility via alpha4 cytoplasmic domain-specific activation of c-Src. Mol Cell Biol. 2005;25:9700-9712.
    • (2005) Mol Cell Biol , vol.25 , pp. 9700-9712
    • Hsia, D.A.1    Lim, S.T.2    Bernard-Trifilo, J.A.3
  • 55
    • 23844477497 scopus 로고    scopus 로고
    • Temporal quantitation of mutant Kit tyrosine kinase signaling attenuated by a novel thiophene kinase inhibitor OSI-930
    • Petti F, Thelemann A, Kahler J, et al. Temporal quantitation of mutant Kit tyrosine kinase signaling attenuated by a novel thiophene kinase inhibitor OSI-930. Mol Cancer Ther. 2005;4:1186-1197.
    • (2005) Mol Cancer Ther , vol.4 , pp. 1186-1197
    • Petti, F.1    Thelemann, A.2    Kahler, J.3
  • 56
    • 1842682019 scopus 로고    scopus 로고
    • Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxis
    • Jolly PS, Bektas M, Olivera A, et al. Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxis. J Exp Med. 2004;199:959-970.
    • (2004) J Exp Med , vol.199 , pp. 959-970
    • Jolly, P.S.1    Bektas, M.2    Olivera, A.3
  • 57
    • 12544256541 scopus 로고    scopus 로고
    • Sphingolipids and the balancing of immune cell function: Lessons from the mast cell
    • Olivera A, Rivera J. Sphingolipids and the balancing of immune cell function: lessons from the mast cell. J Immunol. 2005;174:1153-1158.
    • (2005) J Immunol , vol.174 , pp. 1153-1158
    • Olivera, A.1    Rivera, J.2
  • 58
    • 0027957554 scopus 로고
    • Steel factor and c-kit regulate cell-matrix adhesion
    • Kinashi T, Springer TA. Steel factor and c-kit regulate cell-matrix adhesion. Blood. 1994;83:1033-1038.
    • (1994) Blood , vol.83 , pp. 1033-1038
    • Kinashi, T.1    Springer, T.A.2
  • 59
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell. 1992;69:11-25.
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 60
    • 0028070036 scopus 로고
    • Actin filament organization in activated mast cells is regulated by heterotrimeric and small GTP-binding proteins
    • Norman JC, Price LS, Ridley AJ, Hall A, Koffer A. Actin filament organization in activated mast cells is regulated by heterotrimeric and small GTP-binding proteins. J Cell Biol. 1994;126:1005-1015.
    • (1994) J Cell Biol , vol.126 , pp. 1005-1015
    • Norman, J.C.1    Price, L.S.2    Ridley, A.J.3    Hall, A.4    Koffer, A.5
  • 61
    • 0842346270 scopus 로고    scopus 로고
    • Do phosphoinositide 3-kinases direct lymphocyte navigation?
    • Ward SG. Do phosphoinositide 3-kinases direct lymphocyte navigation? Trends Immunol. 2004;25:67-74.
    • (2004) Trends Immunol , vol.25 , pp. 67-74
    • Ward, S.G.1
  • 62
    • 3242799065 scopus 로고    scopus 로고
    • Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils
    • Filippi MD, Harris CE, Meller J, Gu Y, Zheng Y, Williams DA. Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils. Nat Immunol. 2004;5:744-751.
    • (2004) Nat Immunol , vol.5 , pp. 744-751
    • Filippi, M.D.1    Harris, C.E.2    Meller, J.3    Gu, Y.4    Zheng, Y.5    Williams, D.A.6
  • 63
    • 0141483031 scopus 로고    scopus 로고
    • Role of phosphoinositide 3-kinase signaling in mast cells: New insights from knockout mouse studies
    • Fukao T, Terauchi Y, Kadowaki T, Koyasu S. Role of phosphoinositide 3-kinase signaling in mast cells: new insights from knockout mouse studies. J Mol Med. 2003;81:524-535.
    • (2003) J Mol Med , vol.81 , pp. 524-535
    • Fukao, T.1    Terauchi, Y.2    Kadowaki, T.3    Koyasu, S.4
  • 64
    • 0036195935 scopus 로고    scopus 로고
    • Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice
    • Fukao T, Yamada T, Tanabe M, et al. Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice. Nat Immunol. 2002;3:295-304.
    • (2002) Nat Immunol , vol.3 , pp. 295-304
    • Fukao, T.1    Yamada, T.2    Tanabe, M.3
  • 65
    • 0034106066 scopus 로고    scopus 로고
    • Demonstration of mast cell chemotactic activity in bronchoalveolar lavage fluid collected from asthmatic patients before and during pollen season
    • Olsson N, Rak S, Nilsson G. Demonstration of mast cell chemotactic activity in bronchoalveolar lavage fluid collected from asthmatic patients before and during pollen season. J Allergy Clin Immunol. 2000;105:455-461.
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 455-461
    • Olsson, N.1    Rak, S.2    Nilsson, G.3
  • 66
    • 0031712729 scopus 로고    scopus 로고
    • Demonstration of mast-cell chemotactic activity in nasal lavage fluid: Characterization of one chemotaxin as c-kit ligand, stem cell factor
    • Nilsson G, Hjertson M, Andersson M, et al. Demonstration of mast-cell chemotactic activity in nasal lavage fluid: characterization of one chemotaxin as c-kit ligand, stem cell factor. Allergy. 1998;53:874-879.
    • (1998) Allergy , vol.53 , pp. 874-879
    • Nilsson, G.1    Hjertson, M.2    Andersson, M.3
  • 67
    • 0034993741 scopus 로고    scopus 로고
    • Classes of c-KIT activating mutations: Proposed mechanisms of action and implications for disease classification and therapy
    • Longley BJ, Reguera MJ, Ma Y. Classes of c-KIT activating mutations: proposed mechanisms of action and implications for disease classification and therapy. Leuk Res. 2001;25:571-576.
    • (2001) Leuk Res , vol.25 , pp. 571-576
    • Longley, B.J.1    Reguera, M.J.2    Ma, Y.3
  • 68
    • 0036493872 scopus 로고    scopus 로고
    • The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations
    • Ma Y, Zeng S, Metcalfe DD, et al. The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations. Blood. 2002;99:1741-1744.
    • (2002) Blood , vol.99 , pp. 1741-1744
    • Ma, Y.1    Zeng, S.2    Metcalfe, D.D.3
  • 70
    • 4944253841 scopus 로고    scopus 로고
    • On the way to targeted therapy of mast cell neoplasms: Identification of molecular targets in neoplastic mast cells and evaluation of arising treatment concepts
    • Valent P, Ghannadan M, Akin C, et al. On the way to targeted therapy of mast cell neoplasms: identification of molecular targets in neoplastic mast cells and evaluation of arising treatment concepts. Eur J Clin Invest. 2004;34(suppl 2):41-52.
    • (2004) Eur J Clin Invest , vol.34 , Issue.SUPPL. 2 , pp. 41-52
    • Valent, P.1    Ghannadan, M.2    Akin, C.3


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