The scaffolding adapter Gab2, via Shp-2, regulates Kit-evoked mast cell proliferation by activating the Rac/JNK pathway

Journal of Biological Chemistry

Volumn 281, Issue 39, 2006, Pages 28615-28626

  Yu, Min ^a   Luo, Jincai ^a,d   Yang, Wentian ^a   Wang, Yongping ^a   Mizuki, Masao ^b   Kanakura, Yuzuru ^b   Besmer, Peter ^c   Neel, Benjamin G ^a   Gu, Haihua ^a,e  

^a HARVARD MEDICAL SCHOOL   (United States)

^b OSAKA UNIVERSITY   (Japan)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d PEKING UNIVERSITY   (China)

^e NRB1030N ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROLIFERATION; MAST CELL DEVELOPMENT; PHOSPHORYLATION; STEM CELL FACTOR (SCF);

ACTIVATION ANALYSIS; CELLS; MUTAGENESIS; PHOSPHORUS; PROTEINS; TISSUE;

SCAFFOLDS;

PROTEIN; PROTEIN GAB2; PROTEIN TYROSINE PHOSPHATASE SHP 2; RAC PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; CELL PROLIFERATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE KINASE 4; MAST CELLS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHOPROTEINS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; PROTEIN TYROSINE PHOSPHATASES; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS C-KIT; RAC GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 33749376770     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M603742200     Document Type: Article

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