Amelioration of lupus-like autoimmune disease in NZB/W F1 mice after treatment with a blocking monoclonal antibody specific for complement component C5

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 16, 1996, Pages 8563-8568

  Wang, Yi ^a   Hu, Qile ^a   Madri, Joseph A ^b   Rollins, Scott A ^a   Chodera, Amy ^a   Matis, Louis A ^a  

^a ALEXION PHARMACEUTICALS   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

glomerulonephritis; immune complex; inflammation

Indexed keywords

ANTINUCLEAR ANTIBODY; COMPLEMENT COMPONENT C5; COMPLEMENT COMPONENT C5A; COMPLEMENT MEMBRANE ATTACK COMPLEX; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ANTIBODY TITER; ARTICLE; AUTOIMMUNITY; COMPLEMENT ACTIVATION; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GLOMERULONEPHRITIS; INFLAMMATION; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; ANTIBODIES, BLOCKING; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY COMPLEX; ARTHUS REACTION; COMPLEMENT ACTIVATION; COMPLEMENT C5; FEMALE; GLOMERULONEPHRITIS; HETEROZYGOTE; IMMUNE COMPLEX DISEASES; IMMUNOTHERAPY; KIDNEY; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; MICE, INBRED NZB;

ANIMALIA;

EID: 0029764359     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.16.8563     Document Type: Article

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