Immunoglobulin G-mediated inflammatory responses develop normally in complement-deficient mice

Journal of Experimental Medicine

Volumn 184, Issue 6, 1996, Pages 2385-2392

  Sylvestre, Diana ^a   Clynes, Raphael ^a   Ma, Minga ^b   Warren, Henry ^b   Carroll, Michael C ^b   Ravetch, Jeffrey V ^a,c  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; CYTOTOXIC ANTIBODY; ERYTHROCYTE ANTIBODY; FC RECEPTOR; IMMUNOGLOBULIN G; THROMBOCYTE ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; AUTOIMMUNE HEMOLYTIC ANEMIA; BLEEDING; COMPLEMENT DEFICIENCY; CONTROLLED STUDY; EDEMA; ERYTHROPHAGOCYTOSIS; INFLAMMATION; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTOPENIA;

ANEMIA, HEMOLYTIC; ANIMALS; BLOOD PLATELETS; COMPLEMENT C3; COMPLEMENT C4; ERYTHROCYTES; IMMUNOGLOBULIN G; INFLAMMATION; MICE; MICE, KNOCKOUT; NEUTROPHILS; PHAGOCYTOSIS; RABBITS; THROMBOCYTOPENIA;

EID: 0030458140     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.184.6.2385     Document Type: Article

References (27)

1. Roitt, I., J. Brostoff, and D. Male. 1993. In Immunology, 3rd ed. Mosby, Inc., London. 20.1-20.2.
2. Snyder, E.L. 1995. Transfusion reactions. In Hematology, Basic Principles and Practice, 2nd ed. R. Hoffman, E.J. Benz, S.J. Shattol, B. Furie, H. Cohen, and L.E. Silberstein, editors. Churchill Livingstone Inc., New York.) 2045-2053.
3. Gallin, J.I. 1993. Inflammation. In Fundamental Immunology, 3rd ed., W. Paul, editor. Raven Press, New York. 1015-1032.
4. Arthus, M. 1903. Injections repetees de serum de cheval cuez le lapin. C. R. Soc. Biol. 55:817-820.
5. Cochrane, C.G., and J.J. Muller-Eberhard. 1968. The derivation of two distinct anaphylatoxin activities from the third and fifth components of human complement. J. Exp. Med. 127:371-386.
6. Cochrane, C.G., H.J. Muller-Eberhard, and B.S. Aiken. 1970. Depletion of plasma complement in vivo by a protein of cobra venom: its effect on various immunologic reactions. J. Immunol. 105:55-69.
7. Sylvestre, D.L., and J.V. Ravetch. 1994. Fc receptors initiate the Arthus reaction: redefining the inflammatory cascade. Science (Wash. DC). 265:1095-1098.
8. Clynes, R., and J.V. Ravetch. 1995. Cytotoxic antibodies trigger inflammation through Fc receptors. Immunity. 3:21-26.
9. Ravetch, J.V. 1994. Fc receptors: rubor redux. Cell. 78: 553-560.
10. Takai, T., M. Li, D. Sylvestre, R. Clynes, and J.V. Ravetch. 1994. FcR γ chain deletion results in pleiotrophic effector cell defects. Cell. 76:519-529.
11. Bradley, P.P., D.A. Priebat, R.D. Christensen, and G. Rothstein. 1982. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol. 78:206-209.
12. Mizutani, H., R.W. Engelman, Y. Kurata, S. Ikehara, and R.A. Good. 1993 Development and characterization of monoclonal antiplatelet autoantibodies from autoimmune thrombocytopenic purpura-prone (NZW × BXSB)F1 mice. Blood. 82:837-844.
13. Wessels, M.R., P. Butkos, M. Ma, H.B. Warren, A.L. Lage, and M.C. Carroll. 1995 Studies of group B streptococcal infection in mice deficient in complement C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity. Proc. Natl. Acad. Sci. USA. 92:11490-11494.
14. Deleted in proof.
15. Zhang, Y., B.F. Ramos, and B.A. Jakschik. 1991. Augmentation of reverse Arthus reaction by mast cells in mice. J. Clin. Invest. 88:841-846.
16. Ward, P.A., and C.G. Cochrane. 1965. Bound complement an immunologic injury of blood vessels. J. Exp. Med. 121: 215-233.
17. Weisman, H.F., M.K. Bartow, H.C. Leppo, G.R. Marsh, M.F. Carson, M.P. Concino, K.H. Boyle, M.L. Roux, H.L. Weisfeldt, and D.T. Fearon. 1990 Soluble human complement receptor type I: in vivo inhibitor of complement suppressing post-ischemic myocardial inflammation and necrosis. Science (Wash. DC). 249:146-151
18. Rossi, A.G., K.E. Norman, D. Donigi-Gale, T.S. Shoupe, R. Edwards, and T.J. Williams. 1992. The role of complement, platelet-activating factor and leukotriene B4 in a reversed passive Arthus reaction. Br. J. Phamacol. 107:44-49.
19. Cochrane, C.G., and A. Janoff. 1974. The Arthus reaction: a model of neutrophil and complement-mediated injury. In The Inflammatory Process. B.W. Zweifach, L. Grant, R.T. McCluskey, editors. Academic Press. 85-162.
20. Meryhew N.L., B.S. Handwerger, and R.P. Messner. 1984. Monoclonal antibody-induced murine hemolytic anemia. J. Lab. Clin. Med. 104:591-601.
21. Shibata, T., T. Berney, L. Reininger, Y. Chiche Portiche, S. Ozaki, T. Shirai, and S. Izui. 1990. Monoclonal anti-erythrocyte autoantibodies derived from NZB mice cause hemolytic anemia by two distinct pathological mechanisms. Int. Immunol. 2:1133-1141.
22. Schreiber, A.D., and M.M. Frank. 1972. Role of antibody and complement in the immune clearance and destruction of erythrocytes. I. In vivo effects of IgG and IgM complementfixing sites. J. Clin. Invest. 51:575-582.
23. Soubrane, C. J.M. Tourani, J.M. Andrieu, S. Visonneau, K. Beldjord, D. Israel-Biet, R. Mouawad, J. Bussel, M. Weil, and D. Khayat. 1993. Biological response to and CD-16 monoclonal antibody therapy in a human immunodeficiency virus-related immune thrombocytopenic purpura patient. Blood. 81:15-19.
24. Debre, M., M.C. Bonnetr, W.H. Fridman, E. Carosalla, N. Phillipe, P. Reinert, E. Vilmer, C. Kaplan, J.L. Teillaud, and C. Griscelli. 1993. Infusion of Fc gamma fragments for treatment of children with acute immune throbocytopenic purpura. Lancet. 342:945-949.
25. Blanchette, V., P. Imbach, M. Andrew, M. Adams, J. McMillan, E. Wang, R. Milner, K. Ali, D. Barnard, M. Bernstein, et al., 1994. Randomized trial of intravenous immunoglobulin G, intravenous anti-D, and oral prednisone in childhood acute immune thrombocytopenic purpura. Lancet. 344:703-707.
26. Clarkson, S.B., J.B. Bussel, R.P. Kimberly, J.E. Valinsky, R.L. Nachman, and J.C. Unkeless. 1986. Treatment of refractory immune thrombocytopenic purpura with an anti-Fc gamma receptor antibody. N. Engl. J. Med. 314:1236-1238.
27. Salama, A., C. Mueller-Eckerhardt, and V. Kiefel. 1983. Effect of intravenous immunoglobulin in immune thrombocytopenia. Lancet. ii:193-195.