Leishmania major heat shock protein 70 (HSP70) is not protective in murine models of cutaneous leishmaniasis and stimulates strong humoral responses in cutaneous and visceral leishmaniasis patients

Vaccine

Volumn 25, Issue 21, 2007, Pages 4159-4169

  Rafati, Sima ^a   Gholami, Elham ^a,b   Hassani, Nafiseh ^a,b   Ghaemimanesh, Fatemeh ^a   Taslimi, Yasaman ^a   Taheri, Tahereh ^a   Soong, Lynn ^c  

^a PASTEUR INSTITUTE OF IRAN   (Iran)

^b Khatam University   (Iran)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Cutaneous and visceral leishmaniasis; Heat shock protein 70; Leishmaniasis; Prime boost vaccination

Indexed keywords

HEAT SHOCK PROTEIN 70; IMMUNOLOGIC AGENT; IMMUNOLOGICAL ADJUVANT; PLASMID DNA; RECOMBINANT HEAT SHOCK PROTEIN 70; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; HUMORAL IMMUNITY; IMMUNOGENICITY; INFECTION RESISTANCE; INFECTION SENSITIVITY; LEISHMANIA MAJOR; LYMPHOCYTE PROLIFERATION; MOLECULAR CLONING; MOUSE; MOUSE STRAIN; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; SKIN LEISHMANIASIS; TH1 CELL; TH2 CELL; VISCERAL LEISHMANIASIS;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; CELL PROLIFERATION; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOGLOBULIN G; IRAN; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; LEISHMANIASIS, VISCERAL; LYMPHOCYTES; MANNITOL; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; OLEIC ACIDS; VACCINES, SUBUNIT; VACCINES, SYNTHETIC;

EID: 34247352104     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2007.03.006     Document Type: Article

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