Immunostimulatory properties of the Leishmania infantum heat shock proteins HSP70 and HSP83

Molecular Immunology

Volumn 36, Issue 17, 1999, Pages 1131-1139

  Rico, Ana I ^a   Angel, Sergio O ^a,b   Alonso, Carlos ^a   Requena, Jose M ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b Admin Nac Laboratorios I   (Argentina)

Author keywords

Adjuvant; Heat shock proteins; Leishmania infantum; Splenocytes

Indexed keywords

HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; FEMALE; HUMORAL IMMUNITY; IMMUNOSTIMULATION; LEISHMANIA INFANTUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODY FORMATION; B-LYMPHOCYTES; BASE SEQUENCE; CYCLOSPORINE; DNA PRIMERS; FEMALE; HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; IMMUNIZATION; LEISHMANIA INFANTUM; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; PROTOZOAN PROTEINS; RECOMBINANT FUSION PROTEINS; SPLEEN; TH1 CELLS;

EID: 0033382112     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(99)00136-4     Document Type: Article

References (27)

1. Angel S.O., Requena J.M., Soto M., Criado D., Alonso C. During canine leishmaniasis a protein belonging to the 83-kDa heat-shock protein family elicits a strong humoral response. Acta Trop. 62:1996;45-56.
2. Arnold-Schild D., Hanau D., Spehner D., Schmid C., Rammensee H.-G., de la Salle H., Schild H. Receptor-mediated endocytosis of heat shock proteins by professional antigen-presenting cells. J. Immunol. 162:1999;3757-3760.
3. Barrios C., Lussow A.R., Van Embden J., Van der Zee R., Rappuoli R., Costantino P., et al. Mycobacterial heat-shock proteins as carrier molecules - II: the use of the 70-kDa mycobacterial heat-shock protein as carrier for conjugated vaccines can circumvent the need for adjuvants and Bacillus Calmette Guérin priming. Eur. J. Immunol. 22:1992;1365-1372.
4. Benaroudj N., Fouchaq B., Ladjimi M.M. The COOH-terminal peptide binding domain is essential for self-association of the molecular chaperone HSC70. J. Biol. Chem. 272:1997;8744-8751.
5. Bonorino C., Nardi N.B., Zhang X., Wysocki L.J. Characteristics of the strong antibody response to mycobacterial hsp70: A primary, T cell-dependent IgG response with no evidence of natural priming of gammadelta T cell involvement. J. Immunol. 161:1998;5210-5216.
6. Coffman R.L., Seymour B.W.P., Lebman D.A., Hiraki D.D., Christiansen J.A., Shrader B., et al. The role of helper T cell products in mouse B cell differentiation and isotype regulation. Immunol. Rev. 102:1988;5-28.
7. DeNagel D.C., Pierce S.K. Heat shock proteins in immune responses. Crit. Rev. Immunol. 13:1993;71-81.
8. Günther E. Heat shock protein genes and the major histocompatibility complex. Cur. Top. Microbiol. Immunol. 167:1991;57-68.
9. Haas I.G. BiP - a heat shock protein involved in immunoglobulin chain assembly. Cur. Top. Microbiol. Immunol. 167:1991;71-92.
10. Issekutz A.C. Removal of Gram-negative endotoxin from solutions by affinity chromatography. J. Immunol. Methods. 61:1983;275-281.
11. Kaufmann S.H.E. Heat shock proteins and the immune response. Immunol. Today. 11:1990;129-136.
12. Minowada G., Welch W.J. Clinical implications of the stress response. J. Clin. Invest. 95:1995;3-12.
13. Pierce S.K., DeNagel D.C., Vanbuskirk A.M. A role for heat shock proteins in antigen processing and presentation. Cur. Top. Microbiol. Immunol. 167:1991;83-92.
14. Polla B.S., Kantengwa S. Heat shock proteins and inflammation. Cur. Top. Microbiol. Immunol. 167:1991;93-105.
15. Przepiorka D., Srivastava P.K. Heat shock protein-peptide complexes as immunotherapy for human cancer. Mol. Med. Today. 4:1998;478-484.
16. Quijada L., Requena J.M., Soto M., Alonso C. During canine viscero-cutaneous leishmaniasis the anti-Hsp70 antibodies are specifically elicited by the parasite protein. Parasitology. 112:1996;277-284.
17. Rico, A.I., del Real, G., Soto, M., Quijada, L., Martinez-A., C., Alonso, C., Requena, J.M., 1998. Characterization of the immunostimulatory properties of Leishmania infantum HSP70 by fusion to the Escherichia coli maltose-binding protein in normal and nu/nu BALB/c mice. Infect. Immun. 66, 347-352.
18. Schild H., Arnold-Schild D., Lammert E., Rammensee H.G. Stress proteins and immunity mediated by cytotoxic T lymphocytes. Cur. Op. Immunol. 11:1999;109-113.
19. Schirmbeck R., Gerstner O., Reimann J. Truncated or chimeric endogenous protein antigens gain immunogenicity for B cells by stress protein-facilitated expression. Eur. J. Immunol. 29:1999;1740-1749.
20. Schreiber S.L., Crabtree G.R. The mechanism of action of cyclosporin A and FK506. Immunol. Today. 13:1992;136-142.
21. Shinnick T.M. Heat shock proteins as antigens of bacterial and parasitic pathogens. Cur. Top. Microbiol. Immunol. 167:1991;145-160.
22. Srivastava P.K., Maki G. Stress-induced proteins in immune response to cancer. Cur. Top. Microbiol. Immunol. 167:1991;109-123.
23. Srivastava P.K., Udono H., Blachere N.E., Li Z. Heat shock proteins transfer peptides during antigen processing and CTL priming. Immunogenetics. 39:1994;93-98.
24. Srivastava P.K., Menoret A., Basu S., Binder R.J., McQuade K.L. Heat shock proteins come of age: Primitive functions acquire new roles in an adaptive world. Immunity. 8:1998;657-665.
25. Suzue K., Young R.A. Adjuvant-free hsp70 fusion protein system elicits humoral and cellular immune responses to HIV-1 p24. J. Immunol. 156:1996;873-879.
26. Udono H., Srivastava P.K. Comparison of tumor-specific immunogenicities of stress-induced proteins gp96, hsp90, and hsp70. J. Immunol. 152:1994;5398-5403.
27. Winfield J.B., Jarjour W.N. Stress proteins, autoimmunity, and autoimmune disease. Cur. Top. Microbiol. Immunol. 167:1991;161-189.