Enhancement of DNA vaccine potency by linkage of Plasmodium falciparum malarial antigen gene fused with a fragment of HSP70 gene

Vaccine

Volumn 23, Issue 9, 2005, Pages 1114-1125

  Qazi, Khaleda Rahman ^a   Wikman, Maria ^b   Vasconcelos, Nina Maria ^a   Berzins, Klavs ^a   Ståhl, Stefan ^b   Fernández, Carmen ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b ALBANOVA UNIVERSITY CENTER   (Sweden)

Author keywords

Adjuvants; Carrier; DNA vaccine; Heat shock protein 70; Immunomodulation

Indexed keywords

DNA VACCINE; GAMMA INTERFERON; HEAT SHOCK PROTEIN 70; HYBRID PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GENE CONSTRUCT; GENE FUSION; GENETIC LINKAGE; IMMUNE SYSTEM; IMMUNIZATION; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; TH1 CELL; TRYPANOSOMA CRUZI;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, PROTOZOAN; CERCOPITHECUS AETHIOPS; COS CELLS; FEMALE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MALARIA VACCINES; MALARIA, FALCIPARUM; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MOLECULAR SEQUENCE DATA; TRYPANOSOMA CRUZI; VACCINES, DNA;

EID: 11144246547     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2004.08.033     Document Type: Article

References (51)

1. I.A. Quakyi, L.N. Otoo, D. Pombo, L.Y. Sugars, A. Menon, and A.S. DeGroot Differential non-responsiveness in humans of candidate Plasmodium falciparum vaccine antigens Am J Trop Med Hyg 41 1989 125 134
2. k-restricted T-cell epitopes in the highly repetitive Plasmodium falciparum antigen Pf332 Mol Immunol 34 1997 379 389
3. A.I. Rico, S.O. Angel, C. Alonso, and J.M. Requena Immunostimulatory properties of the Leishmania infantum heat shock proteins HSP70 and HSP83 Mol Immunol 36 1999 1131 1139
4. F. Aosai, M. Chen, H.K. Kang, H.S. Mun, K. Norose, and L.X. Piao Toxoplasma gondii-derived heat shock protein HSP70 functions as a B cell mitogen Cell Stress Chaperones 7 2002 357 364
5. B. Dybdahl, A. Wahba, E. Lien, T.H. Flo, A. Waage, and N. Qureshi Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4 Circulation 12 2002 685 690
6. S. Basu, R.J. Binder, T. Ramalingam, and P.K. Srivastava CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin Immunity 14 2001 303 313
7. R.M. Vabulas, P. Ahmad-Nejad, C. da Costa, T. Miethke, C.J. Kirschning, and H. Hacker Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells J Biol Chem 17 2001 31332 31339
8. A. Kol, A.H. Lichtman, R.W. Finberg, P. Libby, and E.A. Kurt-Jones Cutting edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells J Immunol 164 2000 13 17
9. C. Castelli, A.M. Ciupitu, F. Rini, L. Rivoltini, A. Mazzocchi, and R. Kiessling Human heat shock protein 70 peptide complexes specifically activate antimelanoma T cells Cancer Res 61 2001 222 227
10. H. Udono, and P.K. Srivastava Heat shock protein 70-associated peptides elicit specific cancer immunity J Exp Med 178 1993 1391 1396
11. Y. Tamura, P. Peng, K. Liu, M. Daou, and P.K. Srivastava Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations Science 278 1997 117 120
12. T. Ishii, H. Udono, T. Yamano, H. Ohta, A. Uenaka, and T. Ono Isolation of MHC class I-restricted tumor antigen peptide and its precursors associated with heat shock proteins hsp70, hsp90, and gp96 J Immunol 162 1999 1303 1309
13. A. Menoret, P. Peng, and P.K. Srivastava Association of peptides with heat shock protein gp96 occurs in vivo and not after cell lysis Biochem Biophys Res Commun 262 1999 813 818
14. R. Suto, and P.K. Srivastava A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides Science 269 1995 1585 1588
15. J. Dai, B. Liu, M.M. Caudill, H. Zheng, Y. Qiao, and E.R. Podack Cell surface expression of heat shock protein gp96 enhances cross-presentation of cellular antigens and the generation of tumor-specific T cell memory Cancer Immun 3 2003 1 11
16. H. Singh-Jasuja, R.E. Toes, P. Spee, C. Munz, N. Hilf, and S.P. Schoenberger Cross-presentation of glycoprotein 96-associated antigens on major histocompatibility complex class I molecules requires receptor-mediated endocytosis J Exp Med 191 2000 1965 1974
17. V. Milani, E. Noessner, S. Ghose, M. Kuppner, B. Ahrens, and A. Scharner Heat shock protein 70: role in antigen presentation and immune stimulation Int J Hyperthermia 18 2002 563 575
18. K.L. Rock, S. Gamble, and L. Rothstein Presentation of exogenous antigen with class-I major histocompatibility complex molecules Science 249 1990 918 921
19. A. Scherf, and D. Mattei Cloning and characterization of chromosome breakpoints of Plasmodium falciparum: breakage and new telomere formation occurs frequently and randomly in subtelomeric genes Nucleic Acids Res 20 1992 1491 1496
20. J. Wiesner, D. Mattei, and A. Scherf Biology of giant proteins of Plasmodium: resolution on polyacrylamide-agarose composite gels Parasitol Today 14 1998 38 40
21. J. Gysin, S. Gavoille, D. Mattei, A. Scherf, S. Bonnefoy, and O. Mercereau-Puijalon In vitro phagocytosis inhibition assay for the screening of potential candidate antigens for sub-unit vaccines against the asexual blood stage of Plasmodium falciparum J Immunol Methods 159 1993 209 219
22. C. Andersson, N.-M. Vasconcelos, M. Sievertzon, D. Haddad, S. Liljeqvist, and P. Berglund Comparative immunization study using RNA and DNA constructs encoding a part of the Plasmodium falciparum antigen Pf332 Scand J Immunol 54 2001 117 124
23. Q.K. Rahman, K. Berzins, M.C. Lopez, and C. Fernandez Breaking the non-responsiveness of C57BL/6 mice to the malarial antigen EB200-The role of carrier and adjuvant molecules Scand J Immunol 58 2003 395 403
24. J.B. Ulmer, J.J. Donnelly, S.E. Parker, G.H. Rhodes, P.L. Felgner, and V.J. Dwarki Heterologous protection against influenza by injection of DNA encoding a viral protein Science 259 1993 1745 1749
25. S. Gräslund, R. Falk, E. Brundell, C. Höög, and S. StÅhl A high-stringency proteomics concept aimed for generation of antibodies specific for cDNA-encoded proteins Biotechnol Appl Biochem 35 2002 75 82
26. U. Rüther pUR 250 allows rapid chemical sequencing of both DNA strands of its inserts Nucleic Acids Res 10 1982 5765 5772
27. R. Selden Transfection and expression of cloned DNA Curr Protocols Immunol 2 1995 10 13
28. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
29. N. Ahlborg, D. Haddad, A.B. Siddique, C. Roussilhon, C. Rogier, and J.F. Trape Antibody responses to the repetitive Plasmodium falciparum antigen Pf332 in humans naturally primed to the parasite Clin Exp Immunol 129 2002 318 325
30. M. Sallberg, U. Ruden, L.O. Magnius, E. Norrby, and B. Wahren Rapid "tea-bag" peptide synthesis using 9-fluorenylmethoxycarbonyl (Fmoc) protected amino acids applied for antigenic mapping of viral proteins Immunol Lett 30 1991 59 68
31. S. Lindquist The heat-shock response Annu Rev Biochem 55 1986 1151 1191
32. Y.F. Yang, P. Tan-ariya, Y.D. Sharma, and A. Kilejian The primary structure of a Plasmodium falciparum polypeptide related to heat shock proteins Mol Biochem Parasitol 26 1987 61 67
33. J.M. Requena, M.C. Lopez, A. Jimenez-Ruiz, J.C. dela Torre, and C. Alonso A head-to-tail tandem organization of hsp70 genes in Trypanosoma cruzi Nucleic Acids Res 16 1988 1393 1406
34. D. Mattei, A. Scherf, O. Bensaude, and L.P. da Silva A heat shock-like protein from the human malaria parasite Plasmodium falciparum induces autoantibodies Eur J Immunol 19 1989 1823 1828
35. R. Perraut, A.R. Lussow, S. Gavoille, O. Garraud, H. Matile, and C. Tougne Successful primate immunization with peptides conjugated to purified protein derivative or mycobacterial heat shock proteins in the absence of adjuvants Clin Exp Immunol 93 1993 382 386
36. A.R. Lussow, G. Del Giudice, L. Renia, D. Mazier, J.P. Verhave, and A.S. Verdini Use of a tuberculin purified protein derivative - Asn-Ala-Asn-Pro conjugate in bacillus Calmette-Guerin primed mice overcomes H-2 restriction of the antibody response and avoids the need for adjuvants Proc Natl Acad Sci USA 87 1990 2960 2964
37. A.R. Lussow, C. Barrios, J. van Embden, R. Van der Zee, A.S. Verdini, and A. Pessi Mycobacterial heat-shock proteins as carrier molecules Eur J Immunol 21 1991 2297 2302
38. C. Barrios, A.R. Lussow, J. Van Embden, R. Van der Zee, R. Rappuoli, and P. Costantino Mycobacterial heat-shock proteins as carrier molecules. Part II: The use of the 70-kDa mycobacterial heat-shock protein as carrier for conjugated vaccines can circumvent the need for adjuvants and Bacillus Calmette Guerin priming Eur J Immunol 22 1992 1365 1372
39. T. Lehner, L.A. Bergmeier, Y. Wang, L. Tao, M. Sing, and R. Spallek Heat shock proteins generate beta-chemokines which function as innate adjuvants enhancing adaptive immunity Eur J Immunol 30 2000 594 603
40. A.M. Ciupitu, M. Petersson, K. Kono, J. Charo, and R. Kiessling Immunization with heat shock protein 70 from methylcholanthrene-induced sarcomas induces tumor protection correlating with in vitro T cell responses Cancer Immunol Immunother 51 2002 163 170
41. Q. Fu, W. Zhang, F. Meng, R. Guo, and Z. Yao Study on the anti-tumor efficacy induced by heat shock protein 70-peptide complexes derived from tumor cells Chin Med Sci J 17 2002 153 156
42. T.J. Nieland, M.C. Tan, M. Monne-van Muijen, F. Koning, A.M. Kruisbeek, and G.M. van Bleek Isolation of an immunodominant viral peptide that is endogenously bound to the stress protein GP96/GRP94 Proc Natl Acad Sci USA 93 1996 6135 6139
43. A.M. Ciupitu, M. Petersson, C.L. O'Donnell, K. Williams, S. Jindal, and R. Kiessling Immunization with a lymphocytic choriomeningitis virus peptide mixed with heat shock protein 70 results in protective antiviral immunity and specific cytotoxic T lymphocytes J Exp Med 187 1998 685 691
44. C. Maranon, M.C. Thomas, L. Planelles, and M.C. Lopez The immunization of A2/K(b) transgenic mice with the KMP11-HSP70 fusion protein induces CTL response against human cells expressing the T. cruzi KMP11 antigen: identification of A2-restricted epitopes Mol. Immunol 38 2001 279 287
45. L. Planelles, M.C. Thomas, C. Alonso, and M.C. Lopez DNA immunization with Trypanosoma cruzi HSP70 fused to the KMP11 protein elicits a cytotoxic and humoral immune response against the antigen and leads to protection Infect Immun 69 2001 6558 6563
46. D. Haddad, S. Liljeqvist, S. StÅhl, I. Andersson, P. Perlmann, and K. Berzins Comparative study of DNA-based immunization vectors: effect of secretion signals on the antibody responses in mice FEMS Immunol Med Microbiol 18 1997 193 202
47. D. Haddad, S. Liljeqvist, S. StÅhl, M. Hansson, P. Perlmann, and N. Ahlborg Characterization of antibody responses to a Plasmodium falciparum blood-stage antigen induced by a DNA prime/protein boost immunization protocol Scand J Immunol 49 1999 506 514
48. R. Laylor, N. Porakishvili, J.B. De Souza, J.H. Playfair, P.J. Delves, and T. Lund DNA vaccination favours memory rather than effector B cell responses Clin Exp Immunol 117 1999 106 112
49. T.L. Stevens, A. Bossie, V.M. Sanders, R. Fernandez-Botran, R.L. Coffman, and T.R. Mosmann Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells Nature 334 1988 255 258
50. J.C. Unkeless, E. Scigliano, and V.H. Freedman Structure and function of human and murine receptors for IgG Annu Rev Immunol 6 1988 251 281
51. C.A. Torres, A. Iwasaki, B.H. Barber, and H.L. Robinson Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations J Immunol 158 1997 4529 4532