DNA immunization with Trypanosoma cruzi HSP70 fused to the KMP11 protein elicits a cytotoxic and humoral immune response against the antigen and leads to protection

Infection and Immunity

Volumn 69, Issue 10, 2001, Pages 6558-6563

  Planelles, L ^a   Thomas, M C ^a   Alonso, C ^a   Lopez M C ^a  

^a INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; DNA VACCINE; HEAT SHOCK PROTEIN 70; HYBRID PROTEIN; IMMUNOGLOBULIN G2A;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CHAGAS DISEASE; CHIMERA; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; TRYPANOSOMA CRUZI;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, PROTOZOAN; ANTIBODY FORMATION; ARTIFICIAL GENE FUSION; CERCOPITHECUS AETHIOPS; CHAGAS DISEASE; COS CELLS; DISEASE MODELS, ANIMAL; DNA, PROTOZOAN; FEMALE; GENE EXPRESSION; HSP70 HEAT-SHOCK PROTEINS; IMMUNOGLOBULIN G; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PROTOZOAN PROTEINS; PROTOZOAN VACCINES; T-LYMPHOCYTES, CYTOTOXIC; TRYPANOSOMA CRUZI; VACCINATION; VACCINES, DNA;

EID: 0034824676     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.10.6558-6563.2001     Document Type: Article

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