Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase β in human endothelial cells

British Journal of Pharmacology

Volumn 150, Issue 8, 2007, Pages 1044-1054

  Ritchie, E ^a   Saka, M ^b   MacKenzie, C ^a   Drummond, R ^a   Wheeler Jones, C ^c   Kanke, T ^b   Plevin, R ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b Kowa Company Limited   (Japan)

^c ROYAL VETERINARY COLLEGE   (United Kingdom)

Author keywords

2 furoyl(2f) LIGKV OH; Adenovirus; Human umbilical vein endothelial cells; Inhibitory kappa B kinase; Nuclear factor kappa B; p38 MAP kinase; Proteinase activated receptor

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ADENOVIRUS VECTOR; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CALCIUM ION; CYTOKINE; I KAPPA B ALPHA; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INOSITOL PHOSPHATE; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 4; TRYPSIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CALCIUM MOBILIZATION; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME INHIBITION; FLUORESCENCE; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION;

ADENOVIRIDAE; CALCIUM SIGNALING; CELLS, CULTURED; CYTOKINES; ENDOTHELIAL CELLS; GENES, DOMINANT; HUMANS; I-KAPPA B KINASE; IMIDAZOLES; INOSITOL PHOSPHATES; INTERLEUKIN-1BETA; MAP KINASE SIGNALING SYSTEM; OLIGOPEPTIDES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; PYRIDINES; RECEPTOR, PAR-2; RECEPTORS, THROMBIN; RNA, MESSENGER; TIME FACTORS; TRYPSIN; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 34247218063     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707150     Document Type: Article

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