Interleukin-10 attenuates production of HSV-induced inflammatory mediators by human microglia

GLIA

Volumn 47, Issue 4, 2004, Pages 358-366

  Marques, Cristina P ^a,b   Hu, Shuxian ^a,c   Sheng, Wen ^a   Cheeran, Maxim C J ^a,c   Cox, Diana ^a   Lokensgard, James R ^a,c  

^a MINNEAPOLIS MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Chemokines; Cytokines; Encephalitis; HSV 1

Indexed keywords

ANTIVIRUS AGENT; AUTACOID; CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 4; RANTES; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BRAIN INFECTION; BRAIN INJURY; BRAIN NERVE CELL; BRAIN PROTECTION; CELL FUNCTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; GLIA CELL; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; INFLAMMATION; MICROGLIA; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; REGULATORY MECHANISM; VIRUS ENCEPHALITIS;

ADJUVANTS, IMMUNOLOGIC; CELLS, CULTURED; CHEMOKINES, CC; CHEMOKINES, CXC; ENCEPHALITIS, HERPES SIMPLEX; FETUS; HERPESVIRUS 1, HUMAN; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1; INTERLEUKIN-10; INTERLEUKIN-4; MICROGLIA; NF-KAPPA B; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 4644250845     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/glia.20045     Document Type: Article

References (35)

1. Aurelius E, Andersson B, Forsgren M, Skoldenberg B, Strannegard O. 1994. Cytokines and other markers of intrathecal immune response in patients with herpes simplex encephalitis. J Infect Dis 170:678-681.
2. Carr DJ, Chodosh J, Ash J, Lane TE. 2003. Effect of anti-CXCL10 monoclonal antibody on herpes simplex virus type 1 keratitis and retinal infection. J Virol 77:10037-10046.
3. Chao CC, Hu S, Sheng WS, Bu D, Bukrinsky MI, Peterson PK. 1996. Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism. Glia 16:276-284.
4. Cheeran MC, Hu S, Yager SL, Gekker G, Peterson PK, Lokensgard JR. 2001. Cytomegalovirus induces cytokine and chemokine production differentially in microglia and astrocytes: antiviral implications. J Neurovirol 7:135-147.
5. Cheeran MC, Hu S, Sheng WS, Peterson PK, Lokensgard JR. 2003. CXCL10 production from cytomegalovirus-stimulated microglia is regulated by both human and viral interleukin-10. J Virol 77:4502-4515.
6. Farber JM. 1997. Mig and IP-10: CXC chemokines that target lymphocytes. J Leukoc Biol 61:246-257.
7. Ghiasi H, Osorio Y, Perng GC, Nesburn AB, Wechsler SL. 2001. Recombinant herpes simplex virus type 1 expressing murine interleukin-4 is less virulent than wild-type virus in mice. J Virol 75: 9029-9036.
8. Griffin DE. 1997. Cytokines in the brain during viral infection: clues to HIV-associated dementia. J Clin Invest 100:2948-2951.
9. Hickey WF. 1999. Leukocyte traffic in the central nervous system: the participants and their roles. Semin Immunol 11:125-137.
10. Hu S, Chao CC, Ehrlich LC, Sheng WS, Sutton RL, Rockswold GL, Peterson PK. 1999. Inhibition of microglial cell RANTES production by IL-10 and TGF-beta. J Leukoc Biol 65:815-821.
11. Kuner P, Schubenel R, Hertel C. 1998. Beta-amyloid binds to p57NTR and activates NFkappaB in human neuroblastoma cells. J Neurosci Res 54:798-804.
12. Lee SC, Liu W, Brosnan CF, Dickson DW. 1992. Characterization of primary human fetal dissociated central nervous system cultures with an emphasis on microglia. Lab Invest 67:465-476.
13. Lee SC, Liu W, Dickson DW, Brosnan CF, Berman JW. 1993. Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta. J Immunol 150: 2659-2667.
14. Lin YZ, Yao SY, Veach RA, Torgerson TR, Hawiger J. 1995. Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J Biol Chem 270:14255-14258.
15. Lokensgard JR, Hu S, Sheng W, vanOijen M, Cox D, Cheeran MC, Peterson PK. 2001. Robust expression of TNF-alpha, IL-1beta, RANTES, and IP-10 by human microglial cells during nonproductive infection with herpes simplex virus. J Neurovirol 7:208-219.
16. Lokensgard JR, Cheeran MC, Hu S, Gekker G, Peterson PK. 2002. Glial cell responses to herpesvirus infections: role in defense and immunopathogenesis. J Infect Dis 186(suppl 2):S171-179.
17. Mahalingam S, Farber JM, Karupiah G. 1999. The interferon-inducible chemokines MuMig and Crg-2 exhibit antiviral activity in vivo. J Virol 73:1479-1491.
18. McGrath N, Anderson NE, Croxson MC, Powell KF. 1997. Herpes simplex encephalitis treated with acyclovir: diagnosis and long term outcome. J Neurol Neurosurg Psychiatry 63:321-326.
19. Moore KW, O'Garra A, de Waal Malefyt R, Vieira P, Mosmaan TR. 1993. Interleukin-10. Annu Rev Immunol 11:165-190.
20. Moriuchi H, Moriuchi M, Fauci AS. 1997. Nuclear factor-kappa B potently up-regulates the promoter activity of RANTES, a chemokine that blocks HIV infection. J Immunol 158:3483-3491.
21. Paglinawan R, Malipiero U, Schlapbach R, Frei K, Reith W, Fontana A. 2003. TGFbeta directs gene expression of activated microglia to an anti-inflammatory phenotype strongly focusing on chemokine genes and cell migratory genes. Glia 44:219-231.
22. Peterson PK, Hu S, Salak-Johnson J, Molitor TW, Chao CC. 1997. Differential production of and migratory response to beta chemokines by human microglia and astrocytes. J Infect Dis 175:473-481.
23. Peudenier S, Hery C, Montagnier L, Tardieu M. 1991. Human microglial cells: characterization in cerebral tissue and in primary culture, and study of their susceptibility to HIV-1 infection. Ann Neurol 29:152-161.
24. Rosler A, Pohl M, Braune HJ, Oertel WH, Gemsa D, Sprenger H. 1998. Time course of chemokines in the cerebrospinal fluid and serum during herpes simplex type 1 encephalitis. J Neurol Sci 157:82-89.
25. Sawada M, Suzumura A, Hosoya H, Marunouchi T, Nagatsu T. 1999. Interleukin-10 inhibits both production of cytokines and expression of cytokine receptors in microglia. J Neurochem 72:1466-1471.
26. Sebire G, Emilie D, Wallon C, Hery C, Devergne O, Delfraissy JF, Galanaud P, Tardieu M. 1993. In vitro production of IL-6, IL-1 beta, and tumor necrosis factor-alpha by human embryonic microglial and neural cells. J Immunol 150:1517-1523.
27. Sheng WS, Hu S, Kravitz FH, Peterson PK, Chao CC. 1995. Tumor necrosis factor alpha upregulates human microglial cell production of interleukin-10 in vitro. Clin Diagn Lab Immunol 2:604-608.
28. Skoldenberg B. 1996. Herpes simplex encephalitis. Scand J Infect Dis 100(suppl):8-13.
29. Suzumura A, Sawada M, Yamamoto H, Marunouchi T. 1993. Transforming growth factor-beta suppresses activation and proliferation of microglia in vitro. J Immunol 151:2150-2158.
30. Suzumura A, Sawada M, Itoh Y, Marunouchi T. 1994. Interleukin-4 induces proliferation and activation of microglia but suppresses their induction of class II major histocompatibility complex Watigen expression. J Neuroimmunol 53:209-218.
31. Trifilo MJ, Lane TE. 2003. Adenovirus-mediated expression of CXCL10 in the central nervous system results in T-cell recruitment and limited neuropathology. J Neurovirol 9:315-324.
32. Tumpey TM, Elner VM, Chen SH, Oakes JE, Lausch RN. 1994. Interleukin-10 treatment can suppress stromal keratitis induced by herpes simplex virus type 1. J Immunol 153:2258-2265.
33. Tumpey TM, Cheng H, Yan XT, Oakes JE, Lausch RN. 1998. Chemokine synthesis in the HSV-1-infected cornea and its suppression by interleukin-10. J Leukoc Biol 63:486-492.
34. Wildemann B, Ehrhart K, Storch-Hagenlocher B, Meyding-Lamade U, Steinvorth S, Hacke W, Haas J. 1997. Quantitation of herpes simplex virus type 1 DNA in cells of cerebrospinal fluid of patients with herpes simplex virus encephalitis. Neurology 48:1341-1346.
35. Yan XT, Zhuang M, Oakes JE, Lausch RN. 2001. Autocrine action of IL-10 suppresses proinflammatory mediators and inflammation in the HSV-1-infected cornea. J Leukoc Biol 69:149-157.