-
1
-
-
20444504698
-
The genetic epidemiology of neurodegenerative disease
-
Bertram L. and Tanzi R. E. (2005) The genetic epidemiology of neurodegenerative disease. J. Clin. Invest. 115, 1449-1457.
-
(2005)
J. Clin. Invest
, vol.115
, pp. 1449-1457
-
-
Bertram, L.1
Tanzi, R.E.2
-
2
-
-
1842728419
-
Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease β-secretase (BACE-1)
-
Blasko I., Beer R., Bigl M., et al. (2004) Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease β-secretase (BACE-1). J. Neural Transm. 111, 523-536.
-
(2004)
J. Neural Transm
, vol.111
, pp. 523-536
-
-
Blasko, I.1
Beer, R.2
Bigl, M.3
-
3
-
-
0036226609
-
Early endosomes, late endosomes, and lysosomes display distinct partitioning strategies of inheritance with similarities to Golgi-derived membranes
-
Dunster K., Toh B. H., and Sentry J. W. (2002) Early endosomes, late endosomes, and lysosomes display distinct partitioning strategies of inheritance with similarities to Golgi-derived membranes. Eur. J. Cell Biol. 81, 117-124.
-
(2002)
Eur. J. Cell Biol
, vol.81
, pp. 117-124
-
-
Dunster, K.1
Toh, B.H.2
Sentry, J.W.3
-
4
-
-
0034896748
-
Alzheimer's disease: Molecular concepts and therapeutic targets (Review)
-
Fassbender K., Masters C., and Beyreuther K. (2001) Alzheimer's disease: molecular concepts and therapeutic targets (Review). Naturwissenschaften 88, 261-267.
-
(2001)
Naturwissenschaften
, vol.88
, pp. 261-267
-
-
Fassbender, K.1
Masters, C.2
Beyreuther, K.3
-
5
-
-
0034490025
-
Abeta immunoreactive material is present in several intracellular compartments in transfected, neuronally differentiated, P19 cells expressing the human amyloid β-protein precursor
-
Grant S. M., Ducatenzeiler A., Szyf M., and Cuello A. C. (2000) Abeta immunoreactive material is present in several intracellular compartments in transfected, neuronally differentiated, P19 cells expressing the human amyloid β-protein precursor. J. Alzheimers Dis. 2, 207-222.
-
(2000)
J. Alzheimers Dis
, vol.2
, pp. 207-222
-
-
Grant, S.M.1
Ducatenzeiler, A.2
Szyf, M.3
Cuello, A.C.4
-
6
-
-
0036308233
-
Potential external source of Aβ in biological samples
-
Grimm M. O. W., Tomic I., and Hartmann T. (2002) Potential external source of Aβ in biological samples. Nat. Cell Biol. 4, E164-E165.
-
(2002)
Nat. Cell Biol
, vol.4
-
-
Grimm, M.O.W.1
Tomic, I.2
Hartmann, T.3
-
7
-
-
0035829720
-
Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila
-
Gunawardena S. and Goldstein L. S. (2001) Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila. Neuron 32, 389-401.
-
(2001)
Neuron
, vol.32
, pp. 389-401
-
-
Gunawardena, S.1
Goldstein, L.S.2
-
8
-
-
0242442605
-
Increased expression and processing of the Alzheimer amyloid precursor protein in pancreatic cancer may influence cellular proliferation
-
Hansel D. E., Rahman A., Wehner S., Herzog V., Yeo C. J., and Maitra A. (2003) Increased expression and processing of the Alzheimer amyloid precursor protein in pancreatic cancer may influence cellular proliferation. Cancer Res. 63, 7032-7037.
-
(2003)
Cancer Res
, vol.63
, pp. 7032-7037
-
-
Hansel, D.E.1
Rahman, A.2
Wehner, S.3
Herzog, V.4
Yeo, C.J.5
Maitra, A.6
-
9
-
-
0037135111
-
-
Hardy J. and Selkoe D. J. (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics (Review). Science 297, 353-356. Erratum, 297, 2209.
-
Hardy J. and Selkoe D. J. (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics (Review). Science 297, 353-356. Erratum, 297, 2209.
-
-
-
-
10
-
-
0030848219
-
Carboxy-terminal fragments of β-amyloid precursor protein bind to microtubules and the associated protein tau
-
Islam K. and Levy E. (1997) Carboxy-terminal fragments of β-amyloid precursor protein bind to microtubules and the associated protein tau. Am. J. Pathol. 151, 265-271.
-
(1997)
Am. J. Pathol
, vol.151
, pp. 265-271
-
-
Islam, K.1
Levy, E.2
-
11
-
-
0035939657
-
Golgi clusters and vesicles mediate mitotic inheritance independently of the endoplasmic reticulum
-
Jokitalo E., Cabrera-Poch N., Warren G., and Shima D.T. (2001) Golgi clusters and vesicles mediate mitotic inheritance independently of the endoplasmic reticulum. J. Cell Biol. 154, 317-330.
-
(2001)
J. Cell Biol
, vol.154
, pp. 317-330
-
-
Jokitalo, E.1
Cabrera-Poch, N.2
Warren, G.3
Shima, D.T.4
-
12
-
-
0034075589
-
Axonal membrane proteins are transported in distinct carriers: A two-color video microscopy study in cultured hippocampal neurons
-
Kaether C., Skehel P., and Dotti C. G. (2000) Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons. Mol. Biol. Cell. 11, 1213-1224.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 1213-1224
-
-
Kaether, C.1
Skehel, P.2
Dotti, C.G.3
-
13
-
-
0035818998
-
Kinesin-mediated axonal transport of a membrane compartment containing β-secretase and presenilin-1 requires APP
-
Kamal A., Almenar-Queralt A., LeBlanc J. F., Roberts E. A., and Goldstein L. S. (2001) Kinesin-mediated axonal transport of a membrane compartment containing β-secretase and presenilin-1 requires APP. Nature 414, 643-648.
-
(2001)
Nature
, vol.414
, pp. 643-648
-
-
Kamal, A.1
Almenar-Queralt, A.2
LeBlanc, J.F.3
Roberts, E.A.4
Goldstein, L.S.5
-
14
-
-
0033636136
-
Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I
-
Kamal A., Stokin G. B., Yang Z., Xia C. H., and Goldstein L. S. (2000) Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I. Neuron 28, 449-459.
-
(2000)
Neuron
, vol.28
, pp. 449-459
-
-
Kamal, A.1
Stokin, G.B.2
Yang, Z.3
Xia, C.H.4
Goldstein, L.S.5
-
15
-
-
4043072841
-
Increased expression of amyloid precursor protein in oral squamous cell carcinoma
-
Ko S. Y., Lin S. C., Chang K. W., et al. (2004) Increased expression of amyloid precursor protein in oral squamous cell carcinoma. Int. J. Cancer 111, 727-732.
-
(2004)
Int. J. Cancer
, vol.111
, pp. 727-732
-
-
Ko, S.Y.1
Lin, S.C.2
Chang, K.W.3
-
16
-
-
20044396527
-
Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: Revisited
-
Lazarov O., Morfini G. A., Lee E. B., et al. (2005) Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: Revisited. J. Neurosci. 25, 2386-2395.
-
(2005)
J. Neurosci
, vol.25
, pp. 2386-2395
-
-
Lazarov, O.1
Morfini, G.A.2
Lee, E.B.3
-
17
-
-
0026623085
-
Role of amyloid precursor protein (APP): Study with antisense transfection of human neuroblastoma cells
-
LeBlanc A. C., Kovacs D. M., Chen H. Y., et al. (1992) Role of amyloid precursor protein (APP): study with antisense transfection of human neuroblastoma cells. J. Neurosci. Res. 31, 635-645.
-
(1992)
J. Neurosci. Res
, vol.31
, pp. 635-645
-
-
LeBlanc, A.C.1
Kovacs, D.M.2
Chen, H.Y.3
-
18
-
-
12144286502
-
Amyloid β peptide load is correlated with increased β-secretase activity in sporadic Alzheimer?s disease patients
-
Li R., Lindholm K., Yang L. B., et al. (2004) Amyloid β peptide load is correlated with increased β-secretase activity in sporadic Alzheimer?s disease patients. Proc. Natl. Acad. Sci. U. S. A. 101, 3632-3637.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A
, vol.101
, pp. 3632-3637
-
-
Li, R.1
Lindholm, K.2
Yang, L.B.3
-
19
-
-
9244224675
-
Lengthening of G2/mitosis in cortical precursors from mice lacking β-amyloid precursor protein
-
Lopez-Sanchez N., Muller U., and Frade J. M. (2005) Lengthening of G2/mitosis in cortical precursors from mice lacking β-amyloid precursor protein. Neuroscience 130, 51-60.
-
(2005)
Neuroscience
, vol.130
, pp. 51-60
-
-
Lopez-Sanchez, N.1
Muller, U.2
Frade, J.M.3
-
20
-
-
21544465581
-
An alternative interpretation of the amyloid Abeta hypothesis with regard to the pathogenesis of Alzheimer?s disease
-
Marchesi V. T. (2005) An alternative interpretation of the amyloid Abeta hypothesis with regard to the pathogenesis of Alzheimer?s disease. Proc. Natl. Acad. Sci. U. S. A. 102, 9093-9098.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A
, vol.102
, pp. 9093-9098
-
-
Marchesi, V.T.1
-
21
-
-
19044391196
-
Endoplasmic reticulum positioning and partitioning in mitotic HeLa cells
-
McCullough S. and Lucocq J. (2005) Endoplasmic reticulum positioning and partitioning in mitotic HeLa cells. J. Anat. 206, 415-425.
-
(2005)
J. Anat
, vol.206
, pp. 415-425
-
-
McCullough, S.1
Lucocq, J.2
-
22
-
-
0035313986
-
Amyloid β protein precursor is involved in the growth of human colon carcinoma cell in vitro and in vivo
-
Meng J. Y., Kataoka H., Itoh H. S., and Koono M. (2001) Amyloid β protein precursor is involved in the growth of human colon carcinoma cell in vitro and in vivo. Int. J. Cancer 92, 31-39.
-
(2001)
Int. J. Cancer
, vol.92
, pp. 31-39
-
-
Meng, J.Y.1
Kataoka, H.2
Itoh, H.S.3
Koono, M.4
-
23
-
-
27944444156
-
Coordinated transport of phosphorylated amyloid-β precursor protein and c-Jun NH2-terminal kinase-interacting protein-1
-
Muresan Z. and Muresan V. (2005) Coordinated transport of phosphorylated amyloid-β precursor protein and c-Jun NH2-terminal kinase-interacting protein-1. J. Cell Biol. 171, 615-625.
-
(2005)
J. Cell Biol
, vol.171
, pp. 615-625
-
-
Muresan, Z.1
Muresan, V.2
-
24
-
-
0033427947
-
Production of amyloid β protein precursor as a proteinase inhibitor by human astrocytic tumors
-
Nakagawa T., Kabuto M., Kubota T., Kodera T. S., and Sato K. (1999) Production of amyloid β protein precursor as a proteinase inhibitor by human astrocytic tumors. Anticancer Res. 19, 2963-2968.
-
(1999)
Anticancer Res
, vol.19
, pp. 2963-2968
-
-
Nakagawa, T.1
Kabuto, M.2
Kubota, T.3
Kodera, T.S.4
Sato, K.5
-
25
-
-
0034660602
-
Glutamine synthetase, hemoglobin α-chain, and macrophage migration inhibitory factor binding to amyloid β-protein: Their identification in rat brain by a novel affinity chromatography and in Alzheimer?s disease brain by immunoprecipitation
-
Oyama R., Yamamoto H., and Titani K. (2000) Glutamine synthetase, hemoglobin α-chain, and macrophage migration inhibitory factor binding to amyloid β-protein: their identification in rat brain by a novel affinity chromatography and in Alzheimer?s disease brain by immunoprecipitation. Biochim. Biophys. Acta 1479, 91-102.
-
(2000)
Biochim. Biophys. Acta
, vol.1479
, pp. 91-102
-
-
Oyama, R.1
Yamamoto, H.2
Titani, K.3
-
26
-
-
0034278722
-
The making and breaking of the endoplasmic reticulum (Review)
-
Powell K. S. and Latterich M. (2000) The making and breaking of the endoplasmic reticulum (Review). Traffic 1, 689-694.
-
(2000)
Traffic
, vol.1
, pp. 689-694
-
-
Powell, K.S.1
Latterich, M.2
-
27
-
-
0024342769
-
Amyloid A4 protein and its precursor in Down?s syndrome and in Alzeimer?s disease
-
Rumble B., Retallack R., Hilbich C., et al. (1989) Amyloid A4 protein and its precursor in Down?s syndrome and in Alzeimer?s disease. N. Engl. J. Med. 320, 1446-1452.
-
(1989)
N. Engl. J. Med
, vol.320
, pp. 1446-1452
-
-
Rumble, B.1
Retallack, R.2
Hilbich, C.3
-
28
-
-
0036403838
-
Oxidative stress increases expression and activity of BACE in NT2 neurons
-
Tamagno E., Bardini P., Obbili A., et al. (2002) Oxidative stress increases expression and activity of BACE in NT2 neurons. Neurobiol. Dis. 10, 279-288.
-
(2002)
Neurobiol. Dis
, vol.10
, pp. 279-288
-
-
Tamagno, E.1
Bardini, P.2
Obbili, A.3
-
29
-
-
0019510091
-
Delineation of human thymocyte differentiation pathways utilizing double-staining techniques with monoclonal antibodies
-
Tidman N., Janossy G., Bodger M., Granger S., Kung P. C., and Goldstein G. (1981) Delineation of human thymocyte differentiation pathways utilizing double-staining techniques with monoclonal antibodies. Clin. Exp. Immunol. 45, 457-467.
-
(1981)
Clin. Exp. Immunol
, vol.45
, pp. 457-467
-
-
Tidman, N.1
Janossy, G.2
Bodger, M.3
Granger, S.4
Kung, P.C.5
Goldstein, G.6
-
30
-
-
0032838822
-
Growth curves of children with Down syndrome
-
Toledo C., Alembik Y., Aguirre Jaime A., and Stoll C. (1999) Growth curves of children with Down syndrome. Ann. Genet. 42, 81-90.
-
(1999)
Ann. Genet
, vol.42
, pp. 81-90
-
-
Toledo, C.1
Alembik, Y.2
Aguirre Jaime, A.3
Stoll, C.4
-
31
-
-
23244467989
-
Identification of synaptic plasma membrane proteins co-precipitated with fibrillar beta;-amyloid peptide
-
Verdier Y., Huszar E., Penke B., et al. (2005) Identification of synaptic plasma membrane proteins co-precipitated with fibrillar beta;-amyloid peptide. J. Neurochem. 94, 617-628.
-
(2005)
J. Neurochem
, vol.94
, pp. 617-628
-
-
Verdier, Y.1
Huszar, E.2
Penke, B.3
-
32
-
-
0031470093
-
Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice
-
von Koch C. S., Zheng H., Chen H., et al. (1997) Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice. Neurobiol. Aging 18, 661-669.
-
(1997)
Neurobiol. Aging
, vol.18
, pp. 661-669
-
-
von Koch, C.S.1
Zheng, H.2
Chen, H.3
-
33
-
-
0030604718
-
Kinesin-related proteins at mitotic spindle poles: Function and regulation (Review)
-
Walczak C. E. and Mitchison T. J. (1996) Kinesin-related proteins at mitotic spindle poles: function and regulation (Review). Cell 85, 943-946.
-
(1996)
Cell
, vol.85
, pp. 943-946
-
-
Walczak, C.E.1
Mitchison, T.J.2
-
34
-
-
9144262348
-
Isoform-specific knockout of FE65 leads to impaired learning and memory
-
Wang B., Hu Q., Hearn M. G., et al. (2004) Isoform-specific knockout of FE65 leads to impaired learning and memory. J. Neurosci. Res. 75, 12-24.
-
(2004)
J. Neurosci. Res
, vol.75
, pp. 12-24
-
-
Wang, B.1
Hu, Q.2
Hearn, M.G.3
-
35
-
-
2142815707
-
Increased β-secretase activity and expression in rats following transient cerebral ischemia
-
Wen Y., Onyewuchi O., Yang S., Liu R., and Simpkins J. W. (2004) Increased β-secretase activity and expression in rats following transient cerebral ischemia. Brain Res. 1009, 1-8.
-
(2004)
Brain Res
, vol.1009
, pp. 1-8
-
-
Wen, Y.1
Onyewuchi, O.2
Yang, S.3
Liu, R.4
Simpkins, J.W.5
-
36
-
-
0035965275
-
The transmembrane domain of the Alzheimer?s β-secretase (BACE1) determines its late Golgi localization and access to β-amyloid precursor protein (APP) substrate
-
Yan R., Han P., Miao H., Greengard P., and Xu H. (2001) The transmembrane domain of the Alzheimer?s β-secretase (BACE1) determines its late Golgi localization and access to β-amyloid precursor protein (APP) substrate. J. Biol. Chem. 276, 36,788-36,796.
-
(2001)
J. Biol. Chem
, vol.276
-
-
Yan, R.1
Han, P.2
Miao, H.3
Greengard, P.4
Xu, H.5
-
37
-
-
21844473254
-
Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference
-
Zhu C., Zhao J., Bibikova M., et al. (2005) Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference. Mol. Biol. Cell 16, 3187-3199.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 3187-3199
-
-
Zhu, C.1
Zhao, J.2
Bibikova, M.3
|