Production of amyloid β protein precursor as a proteinase inhibitor by human astrocytic tumors

Anticancer Research

Volumn 19, Issue 4 B, 1999, Pages 2963-2968

  Nakagawa, Takao ^a   Kabuto, Masanori ^a   Kubota, Toshihiko ^a   Kodera, Toshiaki ^a   Sato, Kazufumi ^a  

^a UNIVERSITY OF FUKUI   (Japan)

Author keywords

Amyloid protein precursor; Astrocytic tumor; Invasion; Proteinase inhibitor

Indexed keywords

AMYLOID BETA PROTEIN; MATRIX METALLOPROTEINASE INHIBITOR; MONOCLONAL ANTIBODY; PROTEIN PRECURSOR; PROTEINASE INHIBITOR; SERINE PROTEINASE INHIBITOR;

ARTICLE; ASTROCYTOMA; BRAIN TISSUE; CANCER CELL; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; ENDOTHELIUM CELL; EXPLANT; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEINASE INHIBITION; WESTERN BLOTTING; ZYMOGRAPHY;

ADULT; AGED; AMYLOID BETA-PROTEIN PRECURSOR; ASTROCYTOMA; BLOTTING, WESTERN; BRAIN NEOPLASMS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PROTEASE INHIBITORS;

EID: 0033427947     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Pilkington GJ: Tumour cell migration in the central nervous system. Brain Pathol 4: 157-166, 1994.
2. Paulus W, Tonn JC: Interactions of glioma cells and extracellular matrix. J Neurooncol 24: 87-91, 1995.
3. Nakagawa T, Kubota T, Kabuto M, Fujimoto N, Okada Y: Secretion of matrix metalloproteinase-2 (72 kD gelatinase/type IV collagenase = gelatinase A) by malignant human glioma cell lines: Implications of the growth and cellular invasion of the extracellular matrix. J Neurooncol 28: 13-24, 1996.
4. Liu G, Shuman MA, Cohen RL: Co-expression of urokinase, urokinase receptor and PAI-1 is necessary for optimum invasiveness of cultured lung cancer cells. Int J Cancer 60: 501-506, 1995.
5. Nakagawa T, Kubota T, Kabuto M, Sato K, Kawano H, Hayakawa T, Okada Y: Production of matrix metalloproteinases and tissue inhibitor of metalloproteinases-1 by human brain tumors. J Neurosurg 81: 69-77, 1994.
6. Nakagawa T, Kubota T, Kabuto M, Sato K, Arai Y, Kodera T: Production of tissue inhibitor of metalloproteinases-1 by human astrocytic tumors. Neurol Med Chir (Tokyo) 35: 728-731, 1995.
7. Yamamoto M, Sawaya R, Mohanam S, Loskutoff DJ, Bruner JM, Rao VH, Oka K, Tomonaga M, Nicolson GL, Rao JS: Expression and cellular localization of messenger RNA for plasminogen activator inhibitor type I in human astrocytomas in vivo. Cancer Res 54: 3329-3332, 1994.
8. Arai Y, Kubota T, Nakagawa T, Kabuto M, Sato K, Kobayashi H: Production of urokinase-type plasminogen activator (u-PA) and plasminogen activator inhihitor-1 (PAI-1) in human brain tumors. Acta Neurochir (Wien) 140: 377-384, 1948.
9. Ashall F, Goate AM: Role of the beta-amyloid precursor protein in Alzheimer' s disease. Trends Biochem Sci 19: 42-46, 1994.
10. Itoh H, Kataoka H, Koita H, Nabeshima K, Inoue T, Kangawa K, Xoono M: Establishment of a new human cancer cell line secreting protease nexin-II/amyloid β protein precursor derived from squamous-cell carcinoma of lung. Int J Cancer 49: 436-443, 1991.
11. Kitaguchi N, Takahashi Y, Tokushima Y, Shiojiri S, Ito H: Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity. Nature 331: 530-532, 1988.
12. Ponte P, Gonzalez-DeWhitt P, Schilling J, Miller J, Hsu D, Greenberg B, Davis X, Wallace W, Lieberburg I, Fuller F, Cordell B: A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors. Nature 331: 525-527, 1988.
13. Tanzi RE, McClatchey AI, Lamperti ED, Villa-Komaroff L, Gusella JF, Neve RL: Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease. Nature 331: 528-531, 1988.
14. Miyazaki K, Hasegawa M, Funahashi K, Umeda M: A metallo-proteinase inhibitor domain in Alzheimer amyloid protein precursor. Nature 362: 839-841, 1993.
15. Kleihues P, Burger PC, Scheithauer BW: Histological Typing of Tumours of the Central Nervous System, In WHO International Classification of Tumours, 2nd ed, Springer-Verlag, Berlin, Heidelberg, New York, 1993.
16. Kataoka H, Seguchi K, Iwamura T, Moriyama T, Nabeshima K, Koono M: Reverse-zymographic analysis of protease nexin-II/amyloid protein precursor of human carcinoma cell lines, with special reference to the grade of differentiation and metastatic phenotype. Int J Cancer 60: 123-128, 1995.
17. Towbin H, Staehelin T, Gordon J: Electrophoretic transfer proteins from polyacrylamide gels to nitrocellulose sheets; procedures and some applications. Proc Natl Acad Sci USA 76: 4350-4354, 1979.
18. Weidemann A, Konig G, Bunke D, Fischer P, Salbaum JM, Masters CL, Beyreuther X: Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. Cell 57: 115-126, 1989.
19. Yamamoto M, Sawaya R, Mohanam S, Bindal AK, Bruner JM, Oka K, Rao VH, Tomonaga M, Nicolson GL, Rao JS: Expression and localization of urokinase-type plasminogen activator in human astrocytomas in vivo. Cancer Res 54: 3656-3661, 1994.
20. Sandra A, Rosenblum ML, Mikkelsen T, Yan PS, Ellis KD, Golembieski WA, Sameni M, Rozhin J, Ziegler G, Sloane BF: Cathepsin B expression and localization in glioma progression and invasion. Cancer Res 54: 6027-6031, 1994.
21. Sawaya R, Zuccarello M, Highsmith R: Alpha-1-antitrypsin in human brain tumors. J Neurosurg 67: 258-262, 1987.
22. Keohane ME, Hall SW, VandenBerg SR, Gonias SL: Secretion of a2-macroglobulin, a2-antiplasmin, and plasminogen activator inhihitor-1 by glioblastoma multiforme in primary organ culture. J Neurosurg 73: 234-241, 1990.
23. Hanspal JS, Bushell GR, Ghosh P: Detection of protease inhibitors using substrate-containing sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Anal Biochem 132: 288-293, 1983.
24. Stiel TW, Aab A, Heimburger N: Oxidative inactivation of purified human alpha-2-antiplasmin, antithrombin III, and Cl-inhibitor. Thromb Res 49: 581-589, 1988.
25. Ohgami T, Kitamoto T, Tateishi J: Alzheimer's amyloid precursor protein accumulates within axonal swellings in human brain lesions. Neurosci Lett 136: 75-78, 1992.
26. Alvarez OA, Carmichael DF, DeClerck YA: Inhibition of collagenolytic activity and metastasis of tumor cells by a recombinant human tissue inhibitor of metalloproteinases. J Natl Cancer Inst 82: 589-595, 1990.
27. Nakagawa T, Kubota T, Kabuto M, Kodera T: Captopril inhibits glioma cell invasion in vitro: Involvement of matrix metalloproteinases. Anticancer Res 15: 1985-1900, 1995.
28. Reich R, Thompson EW, Iwamoto Y, Martin GR, Deason JR, Fuller GC, Miskin R: Effects of inhibitors of plasminogen activator, serine proteinases, and collagenase IV on the invasion of basement membranes by metastatic cells. Cancer Res 48: 3307-3312, 1988.
29. Schultz RM, Silberman S, Persky B, Bajkowski AS, Carmichael DF: Inhibition by human recombinant tissue inhibitor of metalloproteinases of human amnion invasion and lung colonization by murine B16-F10 melanormi cells. Cancer Res 48: 5539-5545, 1988.
30. Olson D, Pöllänen J, Hoyer-Hansen G, Ronne E, Sakaguchi K, Wun T-C, Appella E, Dan0 K, Blasi F: Internalization of the urokinase-plasminogen activator inhibitor type-1 complex is mediated by the urokinase receptor. J Biol Chem 267: 9129-9133, 1992.
31. Strongin AY, Collier I, Bannikov G, Marmer BL, Grant GA, Goldberg GI: Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease. J Biol Chem 270: 5331-5338, 1995.
32. Van Nostrand WE, Wagner SL, Farrow JS, Cunningham DD: Immunopurification and protease inhibitory properties of protease nexin-2/amyloid β-protein precursor. J Biol Chem 265: 9541-9594. 1990.
33. Saitoh T, Sundsmo M, Roch J-M, Kimura N, Cole G, Schuberg D, Oltersdorf T, Schenk DB: Secreted form of amyloid β protein precursor is involved in the growth regulation of fibroblasts. Cell 58: 615-622, 1989.
34. Chen M, Yankner BA: An antibody to β amyloid and the amyloid precursor protein inhibits cell-substratum adhesion in many mammalian cell types. Neurosei Lett 125: 223-226, 1991.
35. Ghiso J, Rostagno A, Gardella JE, Liem L, Gorvevic PD, Frangione B: A 109-amino-acid C-terminal fragment of Alzheimer's disease amyloid precursor protein contains a sequence - RHDS - that promotes cell adhesion. Biochem J 288: 1053-1059, 1992.