-
1
-
-
0033304603
-
The glucagon-like peptides
-
Kieffer TJ, Habener JF. The glucagon-like peptides. Endocr Rev 1999; 20: 876-913.
-
(1999)
Endocr Rev
, vol.20
, pp. 876-913
-
-
Kieffer, T.J.1
Habener, J.F.2
-
2
-
-
0002025725
-
On the treatment of diabetes mellitus by acid extract of duodenal mucous membrane
-
Moore B, Edle E, Abram J. On the treatment of diabetes mellitus by acid extract of duodenal mucous membrane. Biochem J 1906; 1: 28-38.
-
(1906)
Biochem J
, vol.1
, pp. 28-38
-
-
Moore, B.1
Edle, E.2
Abram, J.3
-
3
-
-
0003018873
-
Contributions à l'étude des variations physiologiques de la sécrétion interne du pancréas: Rélations entre les sécrétions externe et interne du pancréas
-
Zunz E, La Barre J. Contributions à l'étude des variations physiologiques de la sécrétion interne du pancréas: rélations entre les sécrétions externe et interne du pancréas. Arch Int Physiol Biochim 1929; 31: 20-44.
-
(1929)
Arch Int Physiol Biochim
, vol.31
, pp. 20-44
-
-
Zunz, E.1
La Barre, J.2
-
4
-
-
33845344395
-
Plasma insulin responses to oral and intravenous glucose aministration
-
Elrick H, Stimmler L, Hlad CJ, Arai Y. Plasma insulin responses to oral and intravenous glucose aministration. J Clin Endocrinol Metab 1964; 24: 1076-1082.
-
(1964)
J Clin Endocrinol Metab
, vol.24
, pp. 1076-1082
-
-
Elrick, H.1
Stimmler, L.2
Hlad, C.J.3
Arai, Y.4
-
6
-
-
0022461548
-
Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses
-
Nauck MA, Homberger E, Siegel EG, et al. Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses. J Clin Endocrinol Metab 1986; 63: 492-8.
-
(1986)
J Clin Endocrinol Metab
, vol.63
, pp. 492-498
-
-
Nauck, M.A.1
Homberger, E.2
Siegel, E.G.3
-
7
-
-
0037098963
-
Gastric inhibitory polypeptide: The neglected incretin revisited
-
Meier JJ, Nauck MA, Schmidt WE, Gallwitz B. Gastric inhibitory polypeptide: The neglected incretin revisited. Regul Pept 2002; 107: 1-13.
-
(2002)
Regul Pept
, vol.107
, pp. 1-13
-
-
Meier, J.J.1
Nauck, M.A.2
Schmidt, W.E.3
Gallwitz, B.4
-
8
-
-
0023638829
-
Glucagon-like peptide-1 7-36: A physiological incretin in man
-
Kreymann B, Williams G, Ghatei MA, Bloom SR. Glucagon-like peptide-1 7-36: A physiological incretin in man. Lancet 1987; 2: 1300-4.
-
(1987)
Lancet
, vol.2
, pp. 1300-1304
-
-
Kreymann, B.1
Williams, G.2
Ghatei, M.A.3
Bloom, S.R.4
-
9
-
-
0028234355
-
Proglucagon processing in porcine and human pancreas
-
Holst JJ, Bersani M, Johnsen AH, Kofod H, Hartmann B, Orskov C. Proglucagon processing in porcine and human pancreas. J Biol Chem 1994; 269: 18827-33.
-
(1994)
J Biol Chem
, vol.269
, pp. 18827-18833
-
-
Holst, J.J.1
Bersani, M.2
Johnsen, A.H.3
Kofod, H.4
Hartmann, B.5
Orskov, C.6
-
10
-
-
0023434193
-
Sequence of an intestinal cDNA encoding human gastric inhibitory polypeptide precursor
-
Takeda J, Seino Y, Tanaka K, et al. Sequence of an intestinal cDNA encoding human gastric inhibitory polypeptide precursor. Proc Natl Acad Sci USA 1987; 84: 7005-8.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7005-7008
-
-
Takeda, J.1
Seino, Y.2
Tanaka, K.3
-
11
-
-
0033520869
-
GIP biology and fat metabolism
-
Yip RG, Wolfe MM. GIP biology and fat metabolism. Life Sci 2000; 66: 91-103.
-
(2000)
Life Sci
, vol.66
, pp. 91-103
-
-
Yip, R.G.1
Wolfe, M.M.2
-
12
-
-
0034838323
-
Glucose-dependent insulinotropic polypeptide is a growth factor for beta (INS-1) cells by pleiotropic signalling
-
Trumper A, Trumper K, Trusheim H, Arnold R, Goke B, Horsch D. Glucose-dependent insulinotropic polypeptide is a growth factor for beta (INS-1) cells by pleiotropic signalling. Mol Endocrinol 2001; 15: 1559-70.
-
(2001)
Mol Endocrinol
, vol.15
, pp. 1559-1570
-
-
Trumper, A.1
Trumper, K.2
Trusheim, H.3
Arnold, R.4
Goke, B.5
Horsch, D.6
-
13
-
-
0036687655
-
Mechanisms of mitogenic and anti-apoptotic signalling by glucose-dependent insulinotropic polypeptide in beta(INS-1)-cells
-
Trumper A, Trumper K, Horsch D. Mechanisms of mitogenic and anti-apoptotic signalling by glucose-dependent insulinotropic polypeptide in beta(INS-1)-cells. J Endocrinol 2002; 174: 233-46.
-
(2002)
J Endocrinol
, vol.174
, pp. 233-246
-
-
Trumper, A.1
Trumper, K.2
Horsch, D.3
-
14
-
-
0027215348
-
Dipeptidyl peptidase IV hydrolyses gastric inhibitory polypeptide, glucagons-like peptide-1 (7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum
-
Mentlein R, Gallwitz B, Schmidt WE. Dipeptidyl peptidase IV hydrolyses gastric inhibitory polypeptide, glucagons-like peptide-1 (7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum. Eur J Biochem 1993; 214: 829-35.
-
(1993)
Eur J Biochem
, vol.214
, pp. 829-835
-
-
Mentlein, R.1
Gallwitz, B.2
Schmidt, W.E.3
-
15
-
-
0033766716
-
Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide
-
Deacon CF, Nauck MA, Meier J, Hucking K, Holst JJ. Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide. J Clin Endocrinol Metab 2000; 85: 3575-81.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 3575-3581
-
-
Deacon, C.F.1
Nauck, M.A.2
Meier, J.3
Hucking, K.4
Holst, J.J.5
-
16
-
-
0027391607
-
Preserved incretin activity of glucagon-like peptide 1 (7-36 amide) but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus
-
Nauck MA, Heimesaat MM, Orskov C, Holst JJ, Ebert R, Creutzfeldt W. Preserved incretin activity of glucagon-like peptide 1 (7-36 amide) but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. J Clin Invest 1993; 91: 301-7.
-
(1993)
J Clin Invest
, vol.91
, pp. 301-307
-
-
Nauck, M.A.1
Heimesaat, M.M.2
Orskov, C.3
Holst, J.J.4
Ebert, R.5
Creutzfeldt, W.6
-
17
-
-
9444260482
-
Stimulation of insulin secretion by intravenous bolus injection and continuous infusion of gastric inhibitory polypeptide in patients with type 2 diabetes and healthy control subjects
-
Meier JJ, Gallwitz B, Kask B, et al. Stimulation of insulin secretion by intravenous bolus injection and continuous infusion of gastric inhibitory polypeptide in patients with type 2 diabetes and healthy control subjects. Diabetes 2004; 53 (Suppl 3): S220-4.
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 3
-
-
Meier, J.J.1
Gallwitz, B.2
Kask, B.3
-
18
-
-
0035041250
-
Defective glucose-dependent insulinotropic polypeptide receptor expression in diabetic fatty Zucker rats
-
Lynn FC, Pamir N, Ng EH, McIntosh CH, Kieffer TJ, Pederson RA. Defective glucose-dependent insulinotropic polypeptide receptor expression in diabetic fatty Zucker rats. Diabetes 2001; 50: 1004-11.
-
(2001)
Diabetes
, vol.50
, pp. 1004-1011
-
-
Lynn, F.C.1
Pamir, N.2
Ng, E.H.3
McIntosh, C.H.4
Kieffer, T.J.5
Pederson, R.A.6
-
19
-
-
0141446228
-
Enhancing incretin action for the treatment of type 2 diabetes
-
Drucker DJ. Enhancing incretin action for the treatment of type 2 diabetes. Diabetes Care 2003; 26: 2929-40.
-
(2003)
Diabetes Care
, vol.26
, pp. 2929-2940
-
-
Drucker, D.J.1
-
20
-
-
0023955686
-
Immunoreactive gastric inhibitory polypeptide
-
Krarup T. Immunoreactive gastric inhibitory polypeptide. Endocr Rev 1988; 9: 122-34.
-
(1988)
Endocr Rev
, vol.9
, pp. 122-134
-
-
Krarup, T.1
-
21
-
-
0024511397
-
Glucose dependent insulinotropic polypeptide (GIP) infused intravenously is insulinotropic in the fasting state in type 2 (non-insulin dependent) diabetes mellitus
-
Jones IR, Owens DR, Luzio S, Hayes TM. Glucose dependent insulinotropic polypeptide (GIP) infused intravenously is insulinotropic in the fasting state in type 2 (non-insulin dependent) diabetes mellitus. Horm Metab Res 1989; 2: 23-6.
-
(1989)
Horm Metab Res
, vol.2
, pp. 23-26
-
-
Jones, I.R.1
Owens, D.R.2
Luzio, S.3
Hayes, T.M.4
-
22
-
-
0022617246
-
Reduced incretin effect in type 2(non-insulin-dependent) diabetes
-
Nauch M, Stockmann F, Ebert R, Creutzfeldt W. Reduced incretin effect in type 2(non-insulin-dependent) diabetes. Diabetologia 1986; 29: 46-52.
-
(1986)
Diabetologia
, vol.29
, pp. 46-52
-
-
Nauch, M.1
Stockmann, F.2
Ebert, R.3
Creutzfeldt, W.4
-
23
-
-
0024358835
-
A supplementary inffusion of glucose-dependent insulinotropic polypeptide (GIP) with a meal does not significantly improve the beta cell response or glucose tolerance in type 2 diabetes mellitus
-
Jones IR, Owens DR, Vora J, Luzio SD, Hayes TM. A supplementary inffusion of glucose-dependent insulinotropic polypeptide (GIP) with a meal does not significantly improve the beta cell response or glucose tolerance in type 2 diabetes mellitus. Diabetes Res Clin Pract 1989; 7: 263-9.
-
(1989)
Diabetes Res Clin Pract
, vol.7
, pp. 263-269
-
-
Jones, I.R.1
Owens, D.R.2
Vora, J.3
Luzio, S.D.4
Hayes, T.M.5
-
24
-
-
0036373430
-
Defective amplification of the late phase insulin response to glucose by GIP in obese type II diabetic patients
-
Vilsboll T, Krarup T, Madsbad S, Holst JJ. Defective amplification of the late phase insulin response to glucose by GIP in obese type II diabetic patients. Diabetologia 2002; 45: 1111-9.
-
(2002)
Diabetologia
, vol.45
, pp. 1111-1119
-
-
Vilsboll, T.1
Krarup, T.2
Madsbad, S.3
Holst, J.J.4
-
25
-
-
0035512742
-
Reduced insulinotropic effect of gastric inhibitory polypeptide in first-degree relatives of patients with type 2 diabetes
-
Meier JJ, Hucking, K, Holst JJ, Deacon CF, Schmiegel WH, Nauck MA. Reduced insulinotropic effect of gastric inhibitory polypeptide in first-degree relatives of patients with type 2 diabetes. Diabetes 2001; 50: 2497-504.
-
(2001)
Diabetes
, vol.50
, pp. 2497-2504
-
-
Meier, J.J.1
Hucking, K.2
Holst, J.J.3
Deacon, C.F.4
Schmiegel, W.H.5
Nauck, M.A.6
-
27
-
-
0023008693
-
Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing
-
Mojsov S, Heinrich G, Wilson IB, Ravazzola M, Orci I, Habener JF. Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing. J Biol Chem 1986; 261: 11880-9.
-
(1986)
J Biol Chem
, vol.261
, pp. 11880-11889
-
-
Mojsov, S.1
Heinrich, G.2
Wilson, I.B.3
Ravazzola, M.4
Orci, I.5
Habener, J.F.6
-
28
-
-
0024582789
-
Identification of glucagons-like peptide-1 (7-36) amide in rat brain
-
Yoshimoto S, Hirota M, Ohboshi C, Shima R. Identification of glucagons-like peptide-1 (7-36) amide in rat brain. Ann Clin Biochem 1989; 26: 169-71.
-
(1989)
Ann Clin Biochem
, vol.26
, pp. 169-171
-
-
Yoshimoto, S.1
Hirota, M.2
Ohboshi, C.3
Shima, R.4
-
29
-
-
0027157849
-
Biological effects and metabolic rates of glucagon-like peptide 1(7-36)amide and glucagon-like peptide 1(7-37) in healthy subjects are indistinguishable
-
Orskov C, Wettergren A, Holst JJ. Biological effects and metabolic rates of glucagon-like peptide 1(7-36)amide and glucagon-like peptide 1(7-37) in healthy subjects are indistinguishable. Diabetes 1993; 42: 658-61.
-
(1993)
Diabetes
, vol.42
, pp. 658-661
-
-
Orskov, C.1
Wettergren, A.2
Holst, J.J.3
-
30
-
-
0027248866
-
Normalization of fasting hyperglycaemia by exogenous lucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients
-
Nauck MA, Kleine N, Orskov C, Holst JJ, Willms B, Creutzfeltd W. Normalization of fasting hyperglycaemia by exogenous lucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. Diabetologia 1993; 36: 741-4.
-
(1993)
Diabetologia
, vol.36
, pp. 741-744
-
-
Nauck, M.A.1
Kleine, N.2
Orskov, C.3
Holst, J.J.4
Willms, B.5
Creutzfeltd, W.6
-
31
-
-
0028281773
-
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide 1 in humans
-
Orskov C, Rabenhoj L, Wettergren A, Kofod H, Holst JJ. Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide 1 in humans. Diabetes 1994; 43: 535-9.
-
(1994)
Diabetes
, vol.43
, pp. 535-539
-
-
Orskov, C.1
Rabenhoj, L.2
Wettergren, A.3
Kofod, H.4
Holst, J.J.5
-
32
-
-
0027227370
-
Glucagon-like peptide-1 (1-36) amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: Acute post-prandial and 24-h secretion patterns
-
Elliott RM, Morgan LM, Tredger JA, Deacon S, Wright J, Marks V. Glucagon-like peptide-1 (1-36) amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns. J Endocrinol 1993; 138: 159-66.
-
(1993)
J Endocrinol
, vol.138
, pp. 159-166
-
-
Elliott, R.M.1
Morgan, L.M.2
Tredger, J.A.3
Deacon, S.4
Wright, J.5
Marks, V.6
-
33
-
-
0026510891
-
Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man
-
Eissele R, Goke R, Willemer S, et al. Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man. J Clin Invest 1992; 22: 283-91.
-
(1992)
J Clin Invest
, vol.22
, pp. 283-291
-
-
Eissele, R.1
Goke, R.2
Willemer, S.3
-
35
-
-
0028838030
-
Glucagon-like peptide-1 and glucose-dependent insulin-releasing polypeptide plasma levels in response to nutrients
-
Hermann C, Goke R, Richter G, Fehmann HC, Arnold R, Goke B. Glucagon-like peptide-1 and glucose-dependent insulin-releasing polypeptide plasma levels in response to nutrients. Digestion 1995; 56: 117-26.
-
(1995)
Digestion
, vol.56
, pp. 117-126
-
-
Hermann, C.1
Goke, R.2
Richter, G.3
Fehmann, H.C.4
Arnold, R.5
Goke, B.6
-
36
-
-
33744954242
-
Effects of fat on gastric emptying of and the glycemic, insulin, and incretin responses to a carbohydrate meal in type 2 diabetes
-
Gentilcore D, Chaikomin R, Jones KL, et al. Effects of fat on gastric emptying of and the glycemic, insulin, and incretin responses to a carbohydrate meal in type 2 diabetes. J Clin Endocrinol Metab 2006; 91: 2062-7.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 2062-2067
-
-
Gentilcore, D.1
Chaikomin, R.2
Jones, K.L.3
-
37
-
-
0037403765
-
Effects of fat digestion on appetite, APD motility, and gut hormones in response to duodenal fat infusion in humans
-
Feinle C, O'Donovan D, Daran S, et al. Effects of fat digestion on appetite, APD motility, and gut hormones in response to duodenal fat infusion in humans. Am J Physiol 2003; 284: C798-C807.
-
(2003)
Am J Physiol
, vol.284
-
-
Feinle, C.1
O'Donovan, D.2
Daran, S.3
-
39
-
-
0029118049
-
Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dypeptidyl peptidase IV
-
Kieffer TJ, McIntosh CH, Pederson RA. Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dypeptidyl peptidase IV. Endocrinology 1995; 136: 3585-96.
-
(1995)
Endocrinology
, vol.136
, pp. 3585-3596
-
-
Kieffer, T.J.1
McIntosh, C.H.2
Pederson, R.A.3
-
40
-
-
0038359686
-
Effects of GLP-1-(7-37), and GLP-1-(9-36)NH(2) on intravenous glucose tolerance and glucose-induced insulin secretion in healthy humans
-
Vahl TP, Paty BW, Fuller BD, Prigeon RL, D'Alessio DA. Effects of GLP-1-(7-37), and GLP-1-(9-36)NH(2) on intravenous glucose tolerance and glucose-induced insulin secretion in healthy humans. J Clin Endocrinol Metab 2003; 88: 1772-9.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 1772-1779
-
-
Vahl, T.P.1
Paty, B.W.2
Fuller, B.D.3
Prigeon, R.L.4
D'Alessio, D.A.5
-
41
-
-
0033303516
-
Glucagon-like peptide-1-1(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine
-
Hansen L, Deacon CF, Orskov C, Holst JJ. Glucagon-like peptide-1-1(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine. Endocrinology 1999; 140: 5356-63.
-
(1999)
Endocrinology
, vol.140
, pp. 5356-5363
-
-
Hansen, L.1
Deacon, C.F.2
Orskov, C.3
Holst, J.J.4
-
42
-
-
0033921741
-
Somatostatin restrains the secretion of glucagon-like peptide-1 and 2 from isolated perfused porcine ileum
-
Hansen L, Hartmann B, Bisgaard T, Mineo H, Jørgensen PN, Holst JJ. Somatostatin restrains the secretion of glucagon-like peptide-1 and 2 from isolated perfused porcine ileum. Am J Physiol 2000; 278: E1010-8.
-
(2000)
Am J Physiol
, vol.278
-
-
Hansen, L.1
Hartmann, B.2
Bisgaard, T.3
Mineo, H.4
Jørgensen, P.N.5
Holst, J.J.6
-
43
-
-
0029797540
-
Glucagon-like peptide 1 undergoes differential tissue-specific metabolism in the anesthetized pig
-
Deacon CF, Pridal L, Klarskov L, Olesen M, Holst JJ. Glucagon-like peptide 1 undergoes differential tissue-specific metabolism in the anesthetized pig. Am J Physiol 1996; 2713: E458-64.
-
(1996)
Am J Physiol
, vol.2713
-
-
Deacon, C.F.1
Pridal, L.2
Klarskov, L.3
Olesen, M.4
Holst, J.J.5
-
44
-
-
0029111540
-
Characterization of the processing by human neutral endopeptidase 24.11 of GLP-1(7-36) amide and comparison of the substrate specificity of the enzyme for the other glucagon-like peptides
-
Hupe-Sodmann K, McGregor GP, Bridenbaugh R, et al. Characterization of the processing by human neutral endopeptidase 24.11 of GLP-1(7-36) amide and comparison of the substrate specificity of the enzyme for the other glucagon-like peptides. Regul Pept 1995; 58: 149-56.
-
(1995)
Regul Pept
, vol.58
, pp. 149-156
-
-
Hupe-Sodmann, K.1
McGregor, G.P.2
Bridenbaugh, R.3
-
45
-
-
0030758090
-
Endoproteolysis of glucagon-like peptide (GLP)-1 (7-36) amide by ectopeptidases in RINm5F cells
-
Hupe-Sodmann K, Goke R, Goke B, et al. Endoproteolysis of glucagon-like peptide (GLP)-1 (7-36) amide by ectopeptidases in RINm5F cells. Peptides 1997; 18: 625-32.
-
(1997)
Peptides
, vol.18
, pp. 625-632
-
-
Hupe-Sodmann, K.1
Goke, R.2
Goke, B.3
-
46
-
-
4344675057
-
Therapeutic strategies based on glucagon-like peptide-1
-
Deacon CF. Therapeutic strategies based on glucagon-like peptide-1. Diabetes 2004; 53: 2181-9.
-
(2004)
Diabetes
, vol.53
, pp. 2181-2189
-
-
Deacon, C.F.1
-
47
-
-
0026775150
-
Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagons-like peptide 1
-
Thorens B. Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagons-like peptide 1. Proc Natl Acad Sci U S A 1992; 89: 8641-45.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 8641-8645
-
-
Thorens, B.1
-
48
-
-
0030013475
-
Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor
-
Bullock BP, Heller RS, Habener JF. Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor. Endocrinology 1996; 137: 2968-78.
-
(1996)
Endocrinology
, vol.137
, pp. 2968-2978
-
-
Bullock, B.P.1
Heller, R.S.2
Habener, J.F.3
-
49
-
-
13344282056
-
A role for glucagon-like peptide-1 in the central regulation of feeding
-
Turton MD, O'Shea D, Gunn I, et al. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 1996; 379: 69-72.
-
(1996)
Nature
, vol.379
, pp. 69-72
-
-
Turton, M.D.1
O'Shea, D.2
Gunn, I.3
-
50
-
-
0034652302
-
The role of CNS glucagon-like peptide-1 (7-36) amide receptors in mediating the visceral illness effects of lithium chloride
-
Seeley RJ, Blake K, Rushing PA, et al. The role of CNS glucagon-like peptide-1 (7-36) amide receptors in mediating the visceral illness effects of lithium chloride. J Neurosci 2000; 20: 1616-211.
-
(2000)
J Neurosci
, vol.20
, pp. 1616-1211
-
-
Seeley, R.J.1
Blake, K.2
Rushing, P.A.3
-
51
-
-
0034639946
-
The hepatic vagal reception of intraportal GLP-1 is via receptor different from the pancreatic GLP-1 receptor
-
Nishizawa M, Nakabayashi H, Kawai K. The hepatic vagal reception of intraportal GLP-1 is via receptor different from the pancreatic GLP-1 receptor. J Auton Nerv Syst 2000; 80: 14-21.
-
(2000)
J Auton Nerv Syst
, vol.80
, pp. 14-21
-
-
Nishizawa, M.1
Nakabayashi, H.2
Kawai, K.3
-
52
-
-
0030779816
-
High potency antagonists of the pancreatic glucagons-like peptide-1 receptor
-
Montrose-Rafizadeh C, Yang H, Rodgers BD, Beday A, Pritchette LA. High potency antagonists of the pancreatic glucagons-like peptide-1 receptor. J Biol Chem 1997; 272: 21201-6.
-
(1997)
J Biol Chem
, vol.272
, pp. 21201-21206
-
-
Montrose-Rafizadeh, C.1
Yang, H.2
Rodgers, B.D.3
Beday, A.4
Pritchette, L.A.5
-
53
-
-
0344357096
-
Glucagon-like peptide-1 stimulates insulin gene expression and increases cyclic AMP levels in rat islet cell line
-
Drucker DJ, Philippe J, Mojsov S, Chick WL, Habener JF. Glucagon-like peptide-1 stimulates insulin gene expression and increases cyclic AMP levels in rat islet cell line. Proc Natl Acad Sci U S A 1987; 84: 3434-8.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 3434-3438
-
-
Drucker, D.J.1
Philippe, J.2
Mojsov, S.3
Chick, W.L.4
Habener, J.F.5
-
54
-
-
0026535588
-
Insulinotropic hormone glucagon-like peptide-1(7-37) stimulation of proinsulin gene expression and proinsulin byosynthesis in insulinoma beta TC1 cells
-
Fehmann HC, Habener JF. Insulinotropic hormone glucagon-like peptide-1(7-37) stimulation of proinsulin gene expression and proinsulin byosynthesis in insulinoma beta TC1 cells. Endocrinology 1992; 130: 159-66.
-
(1992)
Endocrinology
, vol.130
, pp. 159-166
-
-
Fehmann, H.C.1
Habener, J.F.2
-
55
-
-
0030913210
-
Glucagon-like peptide-1 can reverse the age-related decline in glucose tolerance in rats
-
Wang Y, Perfetti R, Greig NH, et al. Glucagon-like peptide-1 can reverse the age-related decline in glucose tolerance in rats. J Clin Invest 1997; 99: 2883-9.
-
(1997)
J Clin Invest
, vol.99
, pp. 2883-2889
-
-
Wang, Y.1
Perfetti, R.2
Greig, N.H.3
-
56
-
-
0141953908
-
Glucagon-like peptide-1 synthetic analogs: New therapeutic agents for use in the treatment of diabetes mellitus
-
Holz GG, Chepumy OG. Glucagon-like peptide-1 synthetic analogs: new therapeutic agents for use in the treatment of diabetes mellitus. Curr Med Chem 2003; 10: 2471-83.
-
(2003)
Curr Med Chem
, vol.10
, pp. 2471-2483
-
-
Holz, G.G.1
Chepumy, O.G.2
-
57
-
-
0036959991
-
Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycermic clamp experiments in healthy volunteers
-
Nauck MA, Helmesaat MM, Behele K, et al. Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycermic clamp experiments in healthy volunteers. J Clin Endocrinol Metab 2002; 87: 1239-76.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 1239-1276
-
-
Nauck, M.A.1
Helmesaat, M.M.2
Behele, K.3
-
58
-
-
12244264206
-
The role of GLP-1 in the life and death of pancreatic beta cells
-
Perfetti R, Hui H. The role of GLP-1 in the life and death of pancreatic beta cells. Horm Metab Res 2004; 36: 804-10.
-
(2004)
Horm Metab Res
, vol.36
, pp. 804-810
-
-
Perfetti, R.1
Hui, H.2
-
59
-
-
0030975613
-
Insulinotropic glucagon-like peptide 1 receptor expression in glucagon-producing alpha-cells of the rat endocrine pancreas
-
Heller RS, Kieffer TJ, Habener JF. Insulinotropic glucagon-like peptide 1 receptor expression in glucagon-producing alpha-cells of the rat endocrine pancreas. Diabetes 1997; 46: 785-91.
-
(1997)
Diabetes
, vol.46
, pp. 785-791
-
-
Heller, R.S.1
Kieffer, T.J.2
Habener, J.F.3
-
60
-
-
0029043139
-
Cell and molecular biology of the incretin hormones glucagon-like peptide-1 and glucose-dependent insulin releasing polypeptide
-
Fehmann HC, Goke R, Goke B. Cell and molecular biology of the incretin hormones glucagon-like peptide-1 and glucose-dependent insulin releasing polypeptide. Endocr Rev 1995; 16: 390-410.
-
(1995)
Endocr Rev
, vol.16
, pp. 390-410
-
-
Fehmann, H.C.1
Goke, R.2
Goke, B.3
-
61
-
-
4344708602
-
No impairment f hypoglycemia counterregulation via glucagon with N2211, a GLP-1 derivative, in subjects with type 2 diabetes
-
Nauk MA, El-Ouaghlidi A, Homepesch M, Jacobsen J, Elbroend B. No impairment f hypoglycemia counterregulation via glucagon with N2211, a GLP-1 derivative, in subjects with type 2 diabetes. Diabetes 2003; 52: A128.
-
(2003)
Diabetes
, vol.52
-
-
Nauk, M.A.1
El-Ouaghlidi, A.2
Homepesch, M.3
Jacobsen, J.4
Elbroend, B.5
-
62
-
-
0034062386
-
Effects of glucagon-like peptide-1(7-36)amide on antro-pyloroduodenal motility in the interdigestive state and with duodenal lipid perfusion in humans
-
Schirra J, Houck P, Wank U, Arnold R, Goke B, Katschinski M. Effects of glucagon-like peptide-1(7-36)amide on antro-pyloroduodenal motility in the interdigestive state and with duodenal lipid perfusion in humans. Gut 2000; 46: 622-31.
-
(2000)
Gut
, vol.46
, pp. 622-631
-
-
Schirra, J.1
Houck, P.2
Wank, U.3
Arnold, R.4
Goke, B.5
Katschinski, M.6
-
63
-
-
0030853076
-
Glucagon-like peptide-1 inhibits gastric emptying via vagal afferent-mediated central mechanisms
-
Imeryuz N, Yegen BC, Bozkurt A, Coskun T, Villanueva-Penacarrillo ML, Ulusoy NB. Glucagon-like peptide-1 inhibits gastric emptying via vagal afferent-mediated central mechanisms. Am J Physiol Gastrointest Liver Physiol 1997; 273: G920-7.
-
(1997)
Am J Physiol Gastrointest Liver Physiol
, vol.273
-
-
Imeryuz, N.1
Yegen, B.C.2
Bozkurt, A.3
Coskun, T.4
Villanueva-Penacarrillo, M.L.5
Ulusoy, N.B.6
-
64
-
-
0031767175
-
Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow
-
Wettergren A, Wojdemann M, Holst JJ. Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow. Am J Physiol Gastrointest Liver Physiol 1998; 275: G984-92.
-
(1998)
Am J Physiol Gastrointest Liver Physiol
, vol.275
-
-
Wettergren, A.1
Wojdemann, M.2
Holst, J.J.3
-
65
-
-
0037045845
-
Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: A parallel-group study
-
Zander M, Madsbad S, Madsen JL, Holst JJ. Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study. Lancet 2002; 359: 824-30.
-
(2002)
Lancet
, vol.359
, pp. 824-830
-
-
Zander, M.1
Madsbad, S.2
Madsen, J.L.3
Holst, J.J.4
-
66
-
-
0029903111
-
Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I
-
Orskov C, Poulsen SS, Moller M, Holst JJ. Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I. Diabetes 1996; 45: 832-5.
-
(1996)
Diabetes
, vol.45
, pp. 832-835
-
-
Orskov, C.1
Poulsen, S.S.2
Moller, M.3
Holst, J.J.4
-
67
-
-
0041307370
-
Gastric distension induces c-Fos in medullary GLP-1/2-containing neurons
-
Vrang N, Phifer CB, Corkem MM, Berthoud HR. Gastric distension induces c-Fos in medullary GLP-1/2-containing neurons. Am J Physiol 2003; 285: R470-8.
-
(2003)
Am J Physiol
, vol.285
-
-
Vrang, N.1
Phifer, C.B.2
Corkem, M.M.3
Berthoud, H.R.4
-
68
-
-
4344667831
-
A recombinant human glucagon-like peptide (GLP)-1 albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis
-
Baggio LL, Huang Q, Brown TJ, Drucker DJ. A recombinant human glucagon-like peptide (GLP)-1 albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis. Diabetes 2004; 53: 2492-500.
-
(2004)
Diabetes
, vol.53
, pp. 2492-2500
-
-
Baggio, L.L.1
Huang, Q.2
Brown, T.J.3
Drucker, D.J.4
-
69
-
-
0141615898
-
Suppression of endogenous glucose production by glucagon-like peptide 1 independent of islet hormones: A novel extrapancreatic effect
-
Prigeon RL, Quddusi S, Paty B, D'Alessio DA. Suppression of endogenous glucose production by glucagon-like peptide 1 independent of islet hormones: a novel extrapancreatic effect. Am J Physiol 2003; 285: E701-7.
-
(2003)
Am J Physiol
, vol.285
-
-
Prigeon, R.L.1
Quddusi, S.2
Paty, B.3
D'Alessio, D.A.4
-
70
-
-
12244303683
-
Effects of glucagon-like peptide 1 on the hepatic glucose metabolism
-
D'Alessio DD, Vahl T, Prigeon R. Effects of glucagon-like peptide 1 on the hepatic glucose metabolism. Horm Metab Res 2004; 36: 837-41.
-
(2004)
Horm Metab Res
, vol.36
, pp. 837-841
-
-
D'Alessio, D.D.1
Vahl, T.2
Prigeon, R.3
-
71
-
-
0001095690
-
Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients
-
Vilsboll T, Krarup T, Deacon CF, Madsbad S, Holst JJ. Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients. Diabetes 2001; 50: 609-13.
-
(2001)
Diabetes
, vol.50
, pp. 609-613
-
-
Vilsboll, T.1
Krarup, T.2
Deacon, C.F.3
Madsbad, S.4
Holst, J.J.5
-
72
-
-
0034880691
-
Determinants of the effectiveness of glucagons-like peptide-1 in type 2 patients
-
Toft-Nielsen MB, Madsbad S, Holst JJ. Determinants of the effectiveness of glucagons-like peptide-1 in type 2 patients. J Clin. Endocrinol Metab 2001; 86: 3853-60.
-
(2001)
J Clin. Endocrinol Metab
, vol.86
, pp. 3853-3860
-
-
Toft-Nielsen, M.B.1
Madsbad, S.2
Holst, J.J.3
-
73
-
-
0037312821
-
The influence of GLP-1 on glucose-stimulated insulin secretion: Effects on beta-cell sensitivity in type 2 and nondiabetic subjects
-
Kjems LL, Holst JJ, Volund A, Madsbad S. The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects. Diabetes 2003; 52: 380-6.
-
(2003)
Diabetes
, vol.52
, pp. 380-386
-
-
Kjems, L.L.1
Holst, J.J.2
Volund, A.3
Madsbad, S.4
-
74
-
-
9444236149
-
Editorial: Impact of treatment on islet function in type 2 diabetes
-
Henquin J-C, Boitard C, Ferrannini E, Steiner DF, Efendic S. Editorial: Impact of treatment on islet function in type 2 diabetes. Diabetes 2004; 53: S1-S5.
-
(2004)
Diabetes
, vol.53
-
-
Henquin, J.-C.1
Boitard, C.2
Ferrannini, E.3
Steiner, D.F.4
Efendic, S.5
-
75
-
-
3242730474
-
Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans
-
Holst JJ, Gromada J. Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans. Am J Physiol Endocrinol Metab 2004; 287: E199-E206.
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
-
-
Holst, J.J.1
Gromada, J.2
-
76
-
-
0037850667
-
Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes
-
Fineman MS, Bicsak TA, Shen LZ, et al. Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes. Diabetes Care 2003; 26: 2370-7.
-
(2003)
Diabetes Care
, vol.26
, pp. 2370-2377
-
-
Fineman, M.S.1
Bicsak, T.A.2
Shen, L.Z.3
-
77
-
-
0034814047
-
Exendin-4 reduces fasting and postprandial glucose and decreases energy intake in healthy volunteers
-
Edwards CM, Stanley SA, Davis R, et al. Exendin-4 reduces fasting and postprandial glucose and decreases energy intake in healthy volunteers. Am J Physiol Endocrinol Metab 2001; 281: E155-61.
-
(2001)
Am J Physiol Endocrinol Metab
, vol.281
-
-
Edwards, C.M.1
Stanley, S.A.2
Davis, R.3
-
78
-
-
0036965113
-
The insulinotropic effect of acute exendin-4 administered to humans: Comparison of nondiabetic state to type 2 diabetes
-
Egan JM, Clocquet AR, Elahi D. The insulinotropic effect of acute exendin-4 administered to humans: comparison of nondiabetic state to type 2 diabetes. J Clin Endocrinol Metab 2002; 87: 1282-90.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 1282-1290
-
-
Egan, J.M.1
Clocquet, A.R.2
Elahi, D.3
-
79
-
-
0038497464
-
Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes
-
Kolterman OG, Buse JB, Fineman MS, et al. Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes. J Clin Endocrinol Metab 2003; 88: 3082-9.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 3082-3089
-
-
Kolterman, O.G.1
Buse, J.B.2
Fineman, M.S.3
-
80
-
-
7444228521
-
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
-
Buse JB, Henry RR, Han J, Kim DD, Fineman MS, Baron AD. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care 2004; 27: 2628-35.
-
(2004)
Diabetes Care
, vol.27
, pp. 2628-2635
-
-
Buse, J.B.1
Henry, R.R.2
Han, J.3
Kim, D.D.4
Fineman, M.S.5
Baron, A.D.6
-
81
-
-
18144401971
-
Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
-
DeFronzo RA, Ratner RE, Han J, et al. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. Diabetes Care 2005; 28: 1092-100.
-
(2005)
Diabetes Care
, vol.28
, pp. 1092-1100
-
-
DeFronzo, R.A.1
Ratner, R.E.2
Han, J.3
-
82
-
-
17144371646
-
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea
-
Kendall DM, Riddle MC, Rosenstock J, et al. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea. Diabetes Care 2005; 28: 1083-91.
-
(2005)
Diabetes Care
, vol.28
, pp. 1083-1091
-
-
Kendall, D.M.1
Riddle, M.C.2
Rosenstock, J.3
-
83
-
-
26944477362
-
Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes
-
Heine RJ, Van Gaal LF, Johns D, et al. Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes. Ann Intern Med 2005; 143: 559-69.
-
(2005)
Ann Intern Med
, vol.143
, pp. 559-569
-
-
Heine, R.J.1
Van Gaal, L.F.2
Johns, D.3
-
84
-
-
23944488440
-
Dose-response for glycaemic and metabolic change 28 days after single injection of long-acting release exenatide in diabetic fatty Zucker rats
-
Gedulin BR, Smith P, Prickett KS. Dose-response for glycaemic and metabolic change 28 days after single injection of long-acting release exenatide in diabetic fatty Zucker rats. Diabetologia 2005; 48: 1380-5.
-
(2005)
Diabetologia
, vol.48
, pp. 1380-1385
-
-
Gedulin, B.R.1
Smith, P.2
Prickett, K.S.3
-
85
-
-
0034108646
-
Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration
-
Knudsen LB, Nielsen PF, Huusfeldt PO, et al. Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration. J Med Chem 2000; 43: 1664-9.
-
(2000)
J Med Chem
, vol.43
, pp. 1664-1669
-
-
Knudsen, L.B.1
Nielsen, P.F.2
Huusfeldt, P.O.3
-
86
-
-
0036189831
-
The pharmacokinetics, pharmacodinamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men
-
Agerso H, Jensen LB, Elbrond B, Rolan P, Zdravkovic M. The pharmacokinetics, pharmacodinamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men. Diabetologia 2002; 45: 195-202.
-
(2002)
Diabetologia
, vol.45
, pp. 195-202
-
-
Agerso, H.1
Jensen, L.B.2
Elbrond, B.3
Rolan, P.4
Zdravkovic, M.5
-
87
-
-
0036676385
-
Pharmacokinetics, pharmacodynamics, safety, and tolerability of a single-dose of NN2211, a long-acting glucagon-like peptide 1 derivative, in healthy male subjects
-
Elbrond B, Jakobsen G, Larsen S, et al. Pharmacokinetics, pharmacodynamics, safety, and tolerability of a single-dose of NN2211, a long-acting glucagon-like peptide 1 derivative, in healthy male subjects. Diabetes Care 2002; 25: 1398-404.
-
(2002)
Diabetes Care
, vol.25
, pp. 1398-1404
-
-
Elbrond, B.1
Jakobsen, G.2
Larsen, S.3
-
88
-
-
22644444292
-
Effects of liraglutide (NN2211), a long-acting GLP-1 analogue, on glycemic control and bodyweight in subjects with type 2 diabetes
-
Feinglos MN, Saad MF, Pi-Sunyiert FX, An B, Santiago O. Effects of liraglutide (NN2211), a long-acting GLP-1 analogue, on glycemic control and bodyweight in subjects with type 2 diabetes. Diab Med 2005; 22: 1016-23.
-
(2005)
Diab Med
, vol.22
, pp. 1016-1023
-
-
Feinglos, M.N.1
Saad, M.F.2
Pi-Sunyiert, F.X.3
An, B.4
Santiago, O.5
-
89
-
-
0242725075
-
CJC 1131 a long acting GLP-1 derivative exhibits an extended pharmacokenetic profile in healthy human volunteers
-
Lawrence B, Dreyfus JF, Wen S, Guivarc'h PH, Drucker DJ, Castaigne JP. CJC 1131 a long acting GLP-1 derivative exhibits an extended pharmacokenetic profile in healthy human volunteers. In: American Diabetes Association 63rd Annual Meeting, 2003; 534-P (p.A125).
-
American Diabetes Association 63rd Annual Meeting, 2003; 534-P
-
-
Lawrence, B.1
Dreyfus, J.F.2
Wen, S.3
Guivarc'h, P.H.4
Drucker, D.J.5
Castaigne, J.P.6
-
90
-
-
4644300651
-
Effectiveness of progressive dose-escalation of exenatide (exendin-4) in reducing dose-limiting side effects in subjects with type 2 diabetes
-
Fineman MS, Shen LZ, Taylor K, Kim DD, Baron AD. Effectiveness of progressive dose-escalation of exenatide (exendin-4) in reducing dose-limiting side effects in subjects with type 2 diabetes. Diab Metab Res Rev 2004; 20: 411-7.
-
(2004)
Diab Metab Res Rev
, vol.20
, pp. 411-417
-
-
Fineman, M.S.1
Shen, L.Z.2
Taylor, K.3
Kim, D.D.4
Baron, A.D.5
-
91
-
-
2542451393
-
Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): A 12-week, double-blind, randomised, controlled trial
-
Madsbad S, Schmitz O, Ranstam J, Jakobsen G, Matthews DR. Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): a 12-week, double-blind, randomised, controlled trial. Diabetes Care 2004; 27: 1335-42.
-
(2004)
Diabetes Care
, vol.27
, pp. 1335-1342
-
-
Madsbad, S.1
Schmitz, O.2
Ranstam, J.3
Jakobsen, G.4
Matthews, D.R.5
-
92
-
-
0031916924
-
Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect on glucagon-like peptide-1 in anesthetized pigs
-
Deacon CF, Hughes TE, Holst JJ. Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect on glucagon-like peptide-1 in anesthetized pigs. Diabetes 1998; 47: 764-9.
-
(1998)
Diabetes
, vol.47
, pp. 764-769
-
-
Deacon, C.F.1
Hughes, T.E.2
Holst, J.J.3
-
93
-
-
0036228243
-
Long-term treatment with the dipeptidyl peptidase IV inhibitor P32/98 causes sustained improvements in glucose tolerance, insulin sensitivity, hyperinsulinemia, and β-cell glucose responsiveness in VDF (fa/fa) Zucker rats
-
Pospisilik JA, Stafford SG, Demuth HU, et al. Long-term treatment with the dipeptidyl peptidase IV inhibitor P32/98 causes sustained improvements in glucose tolerance, insulin sensitivity, hyperinsulinemia, and β-cell glucose responsiveness in VDF (fa/fa) Zucker rats. Diabetes 2002; 51: 943-50.
-
(2002)
Diabetes
, vol.51
, pp. 943-950
-
-
Pospisilik, J.A.1
Stafford, S.G.2
Demuth, H.U.3
-
94
-
-
0034666562
-
Improved glucose tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice
-
Ahren B, Holst JJ, Martensson H, Balkan B. Improved glucose tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice. Eur J Pharmacol 2000; 404: 239-45.
-
(2000)
Eur J Pharmacol
, vol.404
, pp. 239-245
-
-
Ahren, B.1
Holst, J.J.2
Martensson, H.3
Balkan, B.4
-
95
-
-
0036583164
-
Inhibition of dipeptidyl peptidase IV improves metabolic control over a 4-week study period in type 2 diabetes
-
Ahrén B, Simonsson E, Larsson H, et al. Inhibition of dipeptidyl peptidase IV improves metabolic control over a 4-week study period in type 2 diabetes. Diabetes Care 2002; 25: 869-75.
-
(2002)
Diabetes Care
, vol.25
, pp. 869-875
-
-
Ahrén, B.1
Simonsson, E.2
Larsson, H.3
-
96
-
-
2442482515
-
Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels in type 2 diabetes
-
Ahrén B, Landin-Olsson M, Jansson PA, Svensson M, Holmes D, Schweizer A. Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels in type 2 diabetes. J Clin Endocrinol Metab 2004; 89: 2078-84.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 2078-2084
-
-
Ahrén, B.1
Landin-Olsson, M.2
Jansson, P.A.3
Svensson, M.4
Holmes, D.5
Schweizer, A.6
-
97
-
-
9444285818
-
Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes
-
Ahren B, Gomis R, Standl E, Mills D, Schweizer A. Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes. Diabetes Care 2004; 27: 2874-80.
-
(2004)
Diabetes Care
, vol.27
, pp. 2874-2880
-
-
Ahren, B.1
Gomis, R.2
Standl, E.3
Mills, D.4
Schweizer, A.5
-
98
-
-
33749871472
-
Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels following an oral glucose tolerance tests in patients with type 2 diabetes
-
Herman GA, Bergman A, Stevens C, et al. Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels following an oral glucose tolerance tests in patients with type 2 diabetes. J Clin Endocrinol Metab 2006; 91(11): 4612-9.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, Issue.11
, pp. 4612-4619
-
-
Herman, G.A.1
Bergman, A.2
Stevens, C.3
-
99
-
-
33750517754
-
Tolerability and pharmacokinetics of metformin and the dipeptidyl peptidase-4 inhibitor sitagliptin when co-administered in patients with type 2 diabetes
-
Herman GA, Bergman A, Yi B, Kipnes M. Tolerability and pharmacokinetics of metformin and the dipeptidyl peptidase-4 inhibitor sitagliptin when co-administered in patients with type 2 diabetes. Curr Med Res Opin 2006; 22: 1939-47.
-
(2006)
Curr Med Res Opin
, vol.22
, pp. 1939-1947
-
-
Herman, G.A.1
Bergman, A.2
Yi, B.3
Kipnes, M.4
-
100
-
-
0034880655
-
Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients
-
Toft-Nielsen MB, Damholt MB, Madsbad S, et al. Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients. J Clin Endocrinol Metab 2001; 86: 3717-23.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 3717-3723
-
-
Toft-Nielsen, M.B.1
Damholt, M.B.2
Madsbad, S.3
-
101
-
-
17844362518
-
Dipeptidyl peptidase inhibitors as new drugs for the treatment of type 2 diabetes
-
Mest H-J, Mentlein R. Dipeptidyl peptidase inhibitors as new drugs for the treatment of type 2 diabetes. Diabetologia 2005; 48: 616-20.
-
(2005)
Diabetologia
, vol.48
, pp. 616-620
-
-
Mest, H.-J.1
Mentlein, R.2
-
102
-
-
0037787851
-
Dipeptidyl-peptidase IV from bench to bedside: An update on structural properties, functions, and clinical aspects of the enzyme DPP IV
-
Lambeir AM, Durinx C, Scharpe S, De Meester I. Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV. Crit Rev Clin Lab Sci 2003; 40: 209-94.
-
(2003)
Crit Rev Clin Lab Sci
, vol.40
, pp. 209-294
-
-
Lambeir, A.M.1
Durinx, C.2
Scharpe, S.3
De Meester, I.4
-
103
-
-
0028323205
-
CD26: A surface protease involved in T-cell activation
-
Fleicher B. CD26: a surface protease involved in T-cell activation. Immunol Today 1994; 15: 180-4.
-
(1994)
Immunol Today
, vol.15
, pp. 180-184
-
-
Fleicher, B.1
-
104
-
-
0038759066
-
Deficiency of CD26 results in a change of cytokine and immunoglobulin secretion after stimulation by pokeweed mitogen
-
Yan S, Marguet D, Dobers J, Reutter W, Fan H. Deficiency of CD26 results in a change of cytokine and immunoglobulin secretion after stimulation by pokeweed mitogen. Eur J Immunol 2003; 33: 1519-27.
-
(2003)
Eur J Immunol
, vol.33
, pp. 1519-1527
-
-
Yan, S.1
Marguet, D.2
Dobers, J.3
Reutter, W.4
Fan, H.5
-
105
-
-
24944436267
-
Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig
-
Plamboeck A, Holst JJ, Carr RD, Deacon CF. Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig. Diabetologia 2005; 48: 1882-90.
-
(2005)
Diabetologia
, vol.48
, pp. 1882-1890
-
-
Plamboeck, A.1
Holst, J.J.2
Carr, R.D.3
Deacon, C.F.4
-
106
-
-
0037687745
-
Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both involved in regulating the metabolic stability of glucagon-like peptide-1 in vivo
-
Plamboeck A, Holst JJ, Carr RD, Deacon CF. Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both involved in regulating the metabolic stability of glucagon-like peptide-1 in vivo. Adv Exp Med Biol 2003; 524: 303-12.
-
(2003)
Adv Exp Med Biol
, vol.524
, pp. 303-312
-
-
Plamboeck, A.1
Holst, J.J.2
Carr, R.D.3
Deacon, C.F.4
-
108
-
-
9444285818
-
Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes
-
Ahren B, Gomis R, Standl E, Mills D, Schweizer A. Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes. Diabetes Care 2004; 27: 2874-80.
-
(2004)
Diabetes Care
, vol.27
, pp. 2874-2880
-
-
Ahren, B.1
Gomis, R.2
Standl, E.3
Mills, D.4
Schweizer, A.5
-
109
-
-
18144401971
-
Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
-
De Fronzo RA, Ratner RE, Han J, Kim DD, Fineman MS, Baron AD. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. Diabetes Care 2005; 28: 1092-100.
-
(2005)
Diabetes Care
, vol.28
, pp. 1092-1100
-
-
De Fronzo, R.A.1
Ratner, R.E.2
Han, J.3
Kim, D.D.4
Fineman, M.S.5
Baron, A.D.6
|