메뉴 건너뛰기




Volumn 28, Issue 5, 2005, Pages 1083-1091

Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea

Author keywords

[No Author keywords available]

Indexed keywords

ANTILIPEMIC AGENT; ANTITHROMBOCYTIC AGENT; CHLORPROPAMIDE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; EXENDIN 4; GLIBENCLAMIDE; GLIMEPIRIDE; GLIPIZIDE; GLUCAGON; GLUCOSE; METFORMIN; PLACEBO; SULFONYLUREA; TOLAZAMIDE; TOLBUTAMIDE;

EID: 17144371646     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.28.5.1083     Document Type: Article
Times cited : (1107)

References (36)
  • 1
    • 0032742992 scopus 로고    scopus 로고
    • The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
    • Weyer C, Bogardus C, Mott DM, Pratley RE: The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest 104:787-794, 1999
    • (1999) J Clin Invest , vol.104 , pp. 787-794
    • Weyer, C.1    Bogardus, C.2    Mott, D.M.3    Pratley, R.E.4
  • 2
    • 0343185923 scopus 로고    scopus 로고
    • Insulin-resistant prediabetic subjects have more atherogenic risk factors than insulin-sensitive prediabetic subjects: Implications for preventing coronary heart disease during the prediabetic state
    • Haffner SM, Mykkanen L, Festa A, Burkes JP, Stern MP: Insulin-resistant prediabetic subjects have more atherogenic risk factors than insulin-sensitive prediabetic subjects: implications for preventing coronary heart disease during the prediabetic state. Circulation 101:975-980, 2000
    • (2000) Circulation , vol.101 , pp. 975-980
    • Haffner, S.M.1    Mykkanen, L.2    Festa, A.3    Burkes, J.P.4    Stern, M.P.5
  • 3
    • 0028817815 scopus 로고
    • UK Prospective Diabetes Study 16. Overview of 6 year's therapy of type II diabetes: A progressive disease
    • UK Prospective Diabetes Study Group: UK Prospective Diabetes Study 16. Overview of 6 year's therapy of type II diabetes: a progressive disease. Diabetes 44:1249-1258, 1995
    • (1995) Diabetes , vol.44 , pp. 1249-1258
  • 4
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in subjects with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study Group: Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in subjects with type 2 diabetes (UKPDS 33). Lancet 352:837-853, 1998
    • (1998) Lancet , vol.352 , pp. 837-853
  • 5
    • 0031964322 scopus 로고    scopus 로고
    • UK Prospective Diabetes Study 28. A randomized trial of efficacy of early addition of metformin in sulfonylurea-treated type 2 diabetes
    • UK Prospective Diabetes Study Group: UK Prospective Diabetes Study 28. A randomized trial of efficacy of early addition of metformin in sulfonylurea-treated type 2 diabetes. Diabetes Care 21:87-92, 1998
    • (1998) Diabetes Care , vol.21 , pp. 87-92
  • 6
    • 1042280201 scopus 로고    scopus 로고
    • Glycemic control from 1988 to 2000 among U.S. adults diganosed with type 2 diabetes
    • Koro CM, Bowlin SJ, Bourgeois N, Fedder DO: Glycemic control from 1988 to 2000 among U.S. adults diganosed with type 2 diabetes. Diabetes Care 27:17-20, 2004
    • (2004) Diabetes Care , vol.27 , pp. 17-20
    • Koro, C.M.1    Bowlin, S.J.2    Bourgeois, N.3    Fedder, D.O.4
  • 8
    • 0033578476 scopus 로고    scopus 로고
    • Pharmacologic therapy for type 2 diabetes mellitus
    • DeFronzo RA: Pharmacologic therapy for type 2 diabetes mellitus. Ann Intern Med 131:281-303, 1999
    • (1999) Ann Intern Med , vol.131 , pp. 281-303
    • DeFronzo, R.A.1
  • 9
    • 0037116638 scopus 로고    scopus 로고
    • Oral antihyperglycemic therapy for type 2 diabetes: Scientific review
    • Inzucchi SE: Oral antihyperglycemic therapy for type 2 diabetes: scientific review. JAMA 287:360-372, 2002
    • (2002) JAMA , vol.287 , pp. 360-372
    • Inzucchi, S.E.1
  • 11
    • 0037167920 scopus 로고    scopus 로고
    • Initial management of glycemia in type 2 diabetes mellitus
    • Nathan DM: Initial management of glycemia in type 2 diabetes mellitus. N Engl J Med 347:1342-1349, 2002
    • (2002) N Engl J Med , vol.347 , pp. 1342-1349
    • Nathan, D.M.1
  • 12
    • 0242269000 scopus 로고    scopus 로고
    • The Treat-to-Target Trial: Randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients
    • Riddle MC, Rosenstock J, Gerich J: The Treat-to-Target Trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients. Diabetes Care 26:3080-3086, 2003
    • (2003) Diabetes Care , vol.26 , pp. 3080-3086
    • Riddle, M.C.1    Rosenstock, J.2    Gerich, J.3
  • 13
    • 1242328748 scopus 로고    scopus 로고
    • Glycemic control with glyburide/metformin tablets in combination with rosiglitazone in patients with type 2 diabetes: A randomized, double-blind trial
    • Dailey GE, Noor MA, Park JS, Bruce S, Fiedorek FT: Glycemic control with glyburide/metformin tablets in combination with rosiglitazone in patients with type 2 diabetes: a randomized, double-blind trial. Am J Med 116:223-229, 2004
    • (2004) Am J Med , vol.116 , pp. 223-229
    • Dailey, G.E.1    Noor, M.A.2    Park, J.S.3    Bruce, S.4    Fiedorek, F.T.5
  • 14
    • 0141446228 scopus 로고    scopus 로고
    • Enhancing incretin action for the treatment of type 2 diabetes
    • Drucker DJ: Enhancing incretin action for the treatment of type 2 diabetes. Diabetes Care 26:2929-2940, 2003
    • (2003) Diabetes Care , vol.26 , pp. 2929-2940
    • Drucker, D.J.1
  • 16
    • 0037850667 scopus 로고    scopus 로고
    • Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes
    • Fineman MS, Bicsak TA, Shen LZ, Taylor K, Gaines E, Varns A, Kim D, Baron AD: Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes. Diabetes Care 26:2370-2377, 2003
    • (2003) Diabetes Care , vol.26 , pp. 2370-2377
    • Fineman, M.S.1    Bicsak, T.A.2    Shen, L.Z.3    Taylor, K.4    Gaines, E.5    Varns, A.6    Kim, D.7    Baron, A.D.8
  • 17
    • 0038519125 scopus 로고    scopus 로고
    • Pharmacology of exenatide (synthetic exendin-4) for the treatment of type 2 diabetes
    • Nielsen LL, Baron AD: Pharmacology of exenatide (synthetic exendin-4) for the treatment of type 2 diabetes. Curr Opinion Investig Drugs 4:401-405, 2003
    • (2003) Curr Opinion Investig Drugs , vol.4 , pp. 401-405
    • Nielsen, L.L.1    Baron, A.D.2
  • 18
    • 0347360186 scopus 로고    scopus 로고
    • Pharmacology of exenatide (synthetic exendin-4): A potential therapeutic for improved glycemic control of type 2 diabetes
    • Nielsen LL, Young AA, Parkes D: Pharmacology of exenatide (synthetic exendin-4): a potential therapeutic for improved glycemic control of type 2 diabetes. Regul Pept 117:77-88, 2004
    • (2004) Regul Pept , vol.117 , pp. 77-88
    • Nielsen, L.L.1    Young, A.A.2    Parkes, D.3
  • 19
    • 3242730474 scopus 로고    scopus 로고
    • Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans
    • Holst JJ, Gromada J: Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans. Am J Physiol Endocrinol Metab 287:E199-E206, 2004
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • Holst, J.J.1    Gromada, J.2
  • 20
    • 0031578033 scopus 로고    scopus 로고
    • Recommendations guiding physicians in biomedical research involving human subjects
    • World Medical Association Declaration of Helsinski: Recommendations guiding physicians in biomedical research involving human subjects (Letter). JAMA 277:925-926, 1997
    • (1997) JAMA , vol.277 , pp. 925-926
  • 21
    • 4644300651 scopus 로고    scopus 로고
    • Effect of progressive dose-escalation of exenatide (synthetic exendin-4) on dose-limiting side-effects in subjects with type 2 diabetes
    • Fineman MS, Shen LZ, Taylor K, Kim DD, Baron AD: Effect of progressive dose-escalation of exenatide (synthetic exendin-4) on dose-limiting side-effects in subjects with type 2 diabetes. Diabetes Metab Res Rev 20:411-417, 2004
    • (2004) Diabetes Metab Res Rev , vol.20 , pp. 411-417
    • Fineman, M.S.1    Shen, L.Z.2    Taylor, K.3    Kim, D.D.4    Baron, A.D.5
  • 24
    • 84950899535 scopus 로고
    • The maximum familywise error rate of Fishers least significant difference test
    • Hayter AJ: The maximum familywise error rate of Fishers least significant difference test. J Am Stat Assoc 396:1000-1004, 1986
    • (1986) J Am Stat Assoc , vol.396 , pp. 1000-1004
    • Hayter, A.J.1
  • 25
    • 0017838539 scopus 로고
    • A high performance liquid chromatography method for hemoglobin A1c
    • Davis JE, McDonald JM, Jarret L: A high performance liquid chromatography method for hemoglobin A1c. Diabetes 27:102-107, 1978
    • (1978) Diabetes , vol.27 , pp. 102-107
    • Davis, J.E.1    McDonald, J.M.2    Jarret, L.3
  • 26
    • 0017844461 scopus 로고
    • A rapid method for the determination of glycosylated hemoglobins using high pressure liquid chromatography
    • Cole RA, Soeldner JS, Dunn PJ, Bunn HF: A rapid method for the determination of glycosylated hemoglobins using high pressure liquid chromatography. Metabolism 27:289-301, 1978
    • (1978) Metabolism , vol.27 , pp. 289-301
    • Cole, R.A.1    Soeldner, J.S.2    Dunn, P.J.3    Bunn, H.F.4
  • 27
    • 0032908654 scopus 로고    scopus 로고
    • Glucose-lowering and insulin-sensitizing actions of exendin-4: Studies in obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta)
    • Young AA, Gedulin BR, Bhavsar S, Bodkin N, Jodka C, Hansen B, Denaro M: Glucose-lowering and insulin-sensitizing actions of exendin-4: studies in obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta). Diabetes 48:1026-1034, 1999
    • (1999) Diabetes , vol.48 , pp. 1026-1034
    • Young, A.A.1    Gedulin, B.R.2    Bhavsar, S.3    Bodkin, N.4    Jodka, C.5    Hansen, B.6    Denaro, M.7
  • 28
    • 0035340019 scopus 로고    scopus 로고
    • Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro
    • Parkes DG, Pittner R, Jodka C, Smith P, Young A: Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro. Metabolism 50:583-589, 2001
    • (2001) Metabolism , vol.50 , pp. 583-589
    • Parkes, D.G.1    Pittner, R.2    Jodka, C.3    Smith, P.4    Young, A.5
  • 30
    • 0036965113 scopus 로고    scopus 로고
    • The insulinotropic effect of acute exendin-4 administered to humans: Comparison of nondiabetic state to type 2 diabetes
    • Egan JM, Clocquet AR, Elahi D : The insulinotropic effect of acute exendin-4 administered to humans: comparison of nondiabetic state to type 2 diabetes. J Clin Endocrinol Metab 87:1282-1290, 2002
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1282-1290
    • Egan, J.M.1    Clocquet, A.R.2    Elahi, D.3
  • 31
    • 0027184119 scopus 로고
    • Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting β-cells
    • Göke R, Fehmann HC, Linn T, Schmidt H, Krause M, Eng J, Göke B: Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting β-cells. J Biol Chem 268:19650-19655, 1993
    • (1993) J Biol Chem , vol.268 , pp. 19650-19655
    • Göke, R.1    Fehmann, H.C.2    Linn, T.3    Schmidt, H.4    Krause, M.5    Eng, J.6    Göke, B.7
  • 33
    • 15444380712 scopus 로고    scopus 로고
    • Exenatide (exendin-4) improves insulin sensitivity and β-cell mass in insulin-resistant obese fa/fa Zucker rats independent of glycemia and body weight
    • Gedulin BR, Nikoulina SE, Smith PA, Gedulin G, Nielsen LL, Baron AD, Parkes D, Young AA: Exenatide (exendin-4) improves insulin sensitivity and β-cell mass in insulin-resistant obese fa/fa Zucker rats independent of glycemia and body weight. Endocrinology. 146:2069-2076, 2005
    • (2005) Endocrinology , vol.146 , pp. 2069-2076
    • Gedulin, B.R.1    Nikoulina, S.E.2    Smith, P.A.3    Gedulin, G.4    Nielsen, L.L.5    Baron, A.D.6    Parkes, D.7    Young, A.A.8
  • 34
    • 7444228521 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes mellitus
    • Buse JB, Henry RR, Han J, Kim DD, Fineman MS, Baron AD: Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes mellitus. Diabetes Care 27:2628-2635, 2004
    • (2004) Diabetes Care , vol.27 , pp. 2628-2635
    • Buse, J.B.1    Henry, R.R.2    Han, J.3    Kim, D.D.4    Fineman, M.S.5    Baron, A.D.6
  • 35
    • 3142658598 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
    • DeFronzo R, Ratner R, Han J, Kim D, Fineman M, Baron A: Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes (Abstract). Diabetologia 47 (Suppl. 1):A280, 2004
    • (2004) Diabetologia , vol.47 , Issue.1 SUPPL.
    • DeFronzo, R.1    Ratner, R.2    Han, J.3    Kim, D.4    Fineman, M.5    Baron, A.6
  • 36
    • 4344713643 scopus 로고    scopus 로고
    • Effect of intravenous infusion of exenatide (synthetic exendin4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia
    • Degn KB, Brock B, Juhl CB, Djurhuus CB, Grubert J, Kim D, Han J, Taylor K, Fineman M, Schmitz O: Effect of intravenous infusion of exenatide (synthetic exendin4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia. Diabetes 53:2397-2403, 2004
    • (2004) Diabetes , vol.53 , pp. 2397-2403
    • Degn, K.B.1    Brock, B.2    Juhl, C.B.3    Djurhuus, C.B.4    Grubert, J.5    Kim, D.6    Han, J.7    Taylor, K.8    Fineman, M.9    Schmitz, O.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.