IKr and IKs remodeling differentially affects QT interval prolongation and dynamic adaptation to heart rate acceleration in bradycardic rabbits

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 292, Issue 4, 2007, Pages

  Suto, Fumiaki ^a   Zhu, Wei ^a   Chan, Alice ^a   Gross, Gil J ^a,b,c  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Bradycardia; Ion channels; Repolarization; Ventricular arrhythmias

Indexed keywords

INWARDLY RECTIFYING POTASSIUM CHANNEL; ISOPRENALINE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; POTASSIUM; POTASSIUM CHANNEL;

ADAPTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRADYCARDIA; COMPLETE HEART BLOCK; CONTROLLED STUDY; HEART MUSCLE CELL; HEART RATE; HEART RIGHT VENTRICLE; MALE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; QT INTERVAL; QT PROLONGATION; TACHYCARDIA; ANIMAL; ARTIFICIAL HEART PACEMAKER; DOWN REGULATION; DRUG EFFECT; HEART BLOCK; HEART VENTRICLE REMODELING; LONG QT SYNDROME; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RABBIT; TORSADE DES POINTES;

ADAPTATION, PHYSIOLOGICAL; ADRENERGIC BETA-AGONISTS; ANIMALS; BRADYCARDIA; DOWN-REGULATION; HEART BLOCK; HEART RATE; ISOPROTERENOL; LONG QT SYNDROME; MALE; PACEMAKER, ARTIFICIAL; PATCH-CLAMP TECHNIQUES; POTASSIUM; POTASSIUM CHANNELS; RABBITS; TORSADES DE POINTES; VENTRICULAR REMODELING;

EID: 34147175379     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00932.2006     Document Type: Article

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