Caspase inhibition reduces lymphocyte apoptosis and improves host immune responses to Trypanosoma cruzi infection

European Journal of Immunology

Volumn 37, Issue 3, 2007, Pages 738-746

  Silva, Elisabeth M ^a   Guillermo, Landi V C ^a   Ribiero Gomes, Flávia L ^a   De Meis, Juliana ^a   Nunes, Marise P ^a,b   Senra, Juliana F V ^b   Soares, Milena B P ^b   DosReis, George A ^a   Lopes, Marcela F ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

Apoptosis; Caspases; Infection; Lymphocyte; Trypanosoma cruzi

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE INHIBITOR; GAMMA INTERFERON; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA; BENZYLOXYCARBONYL VALYL ALANYL (METHYL)ASPARTIC ACID FLUOROMETHYL KETONE; BENZYLOXYCARBONYL-VALYL-ALANYL-(METHYL)ASPARTIC ACID FLUOROMETHYL KETONE; CASPASE; PEPTIDE CHLOROMETHYL KETONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DEATH; CELL INFILTRATION; CHAGAS DISEASE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG TARGETING; ENZYME INHIBITION; EXPERIMENTAL INFECTION; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE; LYMPHOCYTE; LYMPHOCYTE COUNT; MACROPHAGE ACTIVATION; MALE; MEMORY CELL; MOUSE; NONHUMAN; PARASITEMIA; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN CELL; SPLEEN LYMPHOCYTE; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TRYPANOSOMA CRUZI; ANIMAL; BAGG ALBINO MOUSE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; IMMUNOLOGY; PATHOLOGY;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; CASPASES; CHAGAS DISEASE; LYMPHOCYTES; MALE; MICE; MICE, INBRED BALB C; TRYPANOSOMA CRUZI;

EID: 34147115539     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200636790     Document Type: Article

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