메뉴 건너뛰기




Volumn 74, Issue , 2006, Pages 341-355

The Role of the Interleukin-6/gp130 Signaling Pathway in Bone Metabolism

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 130; INTERLEUKIN 6;

EID: 33947724217     PISSN: 00836729     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0083-6729(06)74014-6     Document Type: Review
Times cited : (24)

References (73)
  • 1
    • 0032323828 scopus 로고    scopus 로고
    • Advances in the osteoblast lineage
    • Aubin J.E. Advances in the osteoblast lineage. Biochem. Cell Biol. 76 (1998) 899-910
    • (1998) Biochem. Cell Biol. , vol.76 , pp. 899-910
    • Aubin, J.E.1
  • 3
    • 0030857451 scopus 로고    scopus 로고
    • Activation of the Janus kinase/STAT signal transduction pathway by interleukin-6-type cytokines promotes osteoblast differentiation
    • Bellido T., Borba V.Z., Roberson P., and Monolagas S.C. Activation of the Janus kinase/STAT signal transduction pathway by interleukin-6-type cytokines promotes osteoblast differentiation. Endocrinology 138 (1997) 3666-3676
    • (1997) Endocrinology , vol.138 , pp. 3666-3676
    • Bellido, T.1    Borba, V.Z.2    Roberson, P.3    Monolagas, S.C.4
  • 4
    • 0032516898 scopus 로고    scopus 로고
    • waf-1 gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effect on human osteoblastic cells
    • waf-1 gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effect on human osteoblastic cells. J. Biol. Chem. 273 (1998) 21137-21144
    • (1998) J. Biol. Chem. , vol.273 , pp. 21137-21144
    • Bellido, T.1    O'Brien, C.A.2    Roberson, P.K.3    Manolagas, S.C.4
  • 5
    • 0034813643 scopus 로고    scopus 로고
    • Regulation of osteopro-tegerin secretion from primary cultures of human bone marrow stromal cells
    • Brandstrom H., Bjorkman T., and Ljunggren O. Regulation of osteopro-tegerin secretion from primary cultures of human bone marrow stromal cells. Biochem. Biophys. Res. Commun. 280 (2001) 831-835
    • (2001) Biochem. Biophys. Res. Commun. , vol.280 , pp. 831-835
    • Brandstrom, H.1    Bjorkman, T.2    Ljunggren, O.3
  • 6
    • 0036031676 scopus 로고    scopus 로고
    • gp130 activation by soluble interleukin 6 receptor/interleukin 6 enhances osteoblastic differentiation of human bone marrow-derived from mesenchymal stem cells
    • Erices A., Conget P., Rojas C., and Minguell J. gp130 activation by soluble interleukin 6 receptor/interleukin 6 enhances osteoblastic differentiation of human bone marrow-derived from mesenchymal stem cells. Exp. Cell Res. 180 (2002) 24-32
    • (2002) Exp. Cell Res. , vol.180 , pp. 24-32
    • Erices, A.1    Conget, P.2    Rojas, C.3    Minguell, J.4
  • 7
    • 0035156066 scopus 로고    scopus 로고
    • A functional polymorphic variant in the interleukin-6 gene promoter associated with low bone resorption in postmenopausal women
    • Ferrari S.L., Garnero P., Emond S., Montgomery H., Humphries S.E., and Greenspan S.L. A functional polymorphic variant in the interleukin-6 gene promoter associated with low bone resorption in postmenopausal women. Arthritis Rheum. 44 (2001) 196-201
    • (2001) Arthritis Rheum. , vol.44 , pp. 196-201
    • Ferrari, S.L.1    Garnero, P.2    Emond, S.3    Montgomery, H.4    Humphries, S.E.5    Greenspan, S.L.6
  • 8
    • 0344011473 scopus 로고    scopus 로고
    • Markers of bone remodeling in metastatic bone disease
    • Fohr B., Dunstan C.R., and Seibel M.J. Markers of bone remodeling in metastatic bone disease. J. Clin. Endo & Meta 88 (2003) 5059-5075
    • (2003) J. Clin. Endo & Meta , vol.88 , pp. 5059-5075
    • Fohr, B.1    Dunstan, C.R.2    Seibel, M.J.3
  • 9
    • 0029998565 scopus 로고    scopus 로고
    • Inducible COX-2 mediates the induction of bone formation by mechanical loading in vivo
    • Forwood M.R. Inducible COX-2 mediates the induction of bone formation by mechanical loading in vivo. J. Bone Miner. Res. 11 (1996) 1688-1693
    • (1996) J. Bone Miner. Res. , vol.11 , pp. 1688-1693
    • Forwood, M.R.1
  • 10
    • 0030292721 scopus 로고    scopus 로고
    • Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis
    • Fukuta T. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis. Immunity 5 (1996) 449-460
    • (1996) Immunity , vol.5 , pp. 449-460
    • Fukuta, T.1
  • 11
    • 0029889675 scopus 로고    scopus 로고
    • Involvment of CCAAT/enhancer-binding protein and NF-κB binding sites in IL-6 promoter inhibition by estrogens
    • Galien R., Evans H., and Garcia T. Involvment of CCAAT/enhancer-binding protein and NF-κB binding sites in IL-6 promoter inhibition by estrogens. Mol. Endocrinol. 10 (1996) 713-722
    • (1996) Mol. Endocrinol. , vol.10 , pp. 713-722
    • Galien, R.1    Evans, H.2    Garcia, T.3
  • 12
    • 0031980544 scopus 로고    scopus 로고
    • Expression of IL-6 receptor and gp130 in mouse bone marrow cells during osteoclast differentiation
    • Gao Y., Morita I., Maruo N., Kubota T., Murota S., and Aso T. Expression of IL-6 receptor and gp130 in mouse bone marrow cells during osteoclast differentiation. Bone 22 (1998) 487-493
    • (1998) Bone , vol.22 , pp. 487-493
    • Gao, Y.1    Morita, I.2    Maruo, N.3    Kubota, T.4    Murota, S.5    Aso, T.6
  • 13
    • 1242339610 scopus 로고    scopus 로고
    • IL-6, LIF, and TNFα regulation of GM-CSF inhibition of osteoclastogenesis in vitro
    • Gorny G., Shaw A., and Oursler M.J. IL-6, LIF, and TNFα regulation of GM-CSF inhibition of osteoclastogenesis in vitro. Exp. Cell Res. 294 (2004) 149-158
    • (2004) Exp. Cell Res. , vol.294 , pp. 149-158
    • Gorny, G.1    Shaw, A.2    Oursler, M.J.3
  • 14
    • 0029088732 scopus 로고
    • Adenyl cyclase and IL-6 are downstream effectors of parathyroid hormone regulating in stimulation of bone resorption
    • Greenfield E.M., Shaw S.M., Gornik S.A., and Banks M.A. Adenyl cyclase and IL-6 are downstream effectors of parathyroid hormone regulating in stimulation of bone resorption. J. Clin. Invest. 96 (1995) 1238-1244
    • (1995) J. Clin. Invest. , vol.96 , pp. 1238-1244
    • Greenfield, E.M.1    Shaw, S.M.2    Gornik, S.A.3    Banks, M.A.4
  • 17
    • 0033790375 scopus 로고    scopus 로고
    • gp130 cytokine family and bone cells
    • Heymann D., and Rousselle A.-V. gp130 cytokine family and bone cells. Cytokine 12 (2000) 1455-1468
    • (2000) Cytokine , vol.12 , pp. 1455-1468
    • Heymann, D.1    Rousselle, A.-V.2
  • 18
    • 0029932635 scopus 로고    scopus 로고
    • Osteoclast are not the major source of interleukin-6 in mouse parietal bone
    • Holt I., Davie M.W.J., and Marshall M.J. Osteoclast are not the major source of interleukin-6 in mouse parietal bone. Bone 18 (1996) 221-226
    • (1996) Bone , vol.18 , pp. 221-226
    • Holt, I.1    Davie, M.W.J.2    Marshall, M.J.3
  • 19
    • 0033870605 scopus 로고    scopus 로고
    • Cyclooxygenase regulates human oropharyngeal carcinomas via the proinflammatory cytokine interleukin-6: A general role for inflammation?
    • Hong S.H., Ondrey F.C., Avis I.M., Chen Z., Loukinova E., Cavanaugh Jr. P.F., Waes C.V., and Mulshine J.L. Cyclooxygenase regulates human oropharyngeal carcinomas via the proinflammatory cytokine interleukin-6: A general role for inflammation?. FASEB J. 14 (2000) 1499-1507
    • (2000) FASEB J. , vol.14 , pp. 1499-1507
    • Hong, S.H.1    Ondrey, F.C.2    Avis, I.M.3    Chen, Z.4    Loukinova, E.5    Cavanaugh Jr., P.F.6    Waes, C.V.7    Mulshine, J.L.8
  • 20
    • 0027241733 scopus 로고
    • Interleukin-6 inhibits bone formation in vitro
    • Hughes F.J., and Howells G.L. Interleukin-6 inhibits bone formation in vitro. Bone Miner. 21 (1993) 21-28
    • (1993) Bone Miner. , vol.21 , pp. 21-28
    • Hughes, F.J.1    Howells, G.L.2
  • 23
    • 34347367005 scopus 로고    scopus 로고
    • Osteoclst function is activated by osteoblastic cells through mechanism involving cell-to-cell contact
    • Jimi E., Nakamura I., Amano H., Taguchi Y., Tsurakai T., Tamura M., Takahashi N., and Suda T. Osteoclst function is activated by osteoblastic cells through mechanism involving cell-to-cell contact. Endocrinology 137 (1996) 2187-2190
    • (1996) Endocrinology , vol.137 , pp. 2187-2190
    • Jimi, E.1    Nakamura, I.2    Amano, H.3    Taguchi, Y.4    Tsurakai, T.5    Tamura, M.6    Takahashi, N.7    Suda, T.8
  • 24
    • 1542297244 scopus 로고    scopus 로고
    • IL-6 signal transduction and its physiological roles: The signal orchestration model
    • Kamimura D., Ishihara K., and Hirano T. IL-6 signal transduction and its physiological roles: The signal orchestration model. Rev. Physiol. Biochem. Pharmacol. 149 (2003) 1-38
    • (2003) Rev. Physiol. Biochem. Pharmacol. , vol.149 , pp. 1-38
    • Kamimura, D.1    Ishihara, K.2    Hirano, T.3
  • 25
    • 0024360388 scopus 로고
    • The biology of interleukin-6
    • Kishimoto T. The biology of interleukin-6. Blood 74 (1989) 1-10
    • (1989) Blood , vol.74 , pp. 1-10
    • Kishimoto, T.1
  • 26
    • 0029084805 scopus 로고
    • Interleukin-6 family of cytokines and gp130
    • Kishimoto T., Akira S., Narazaki M., and Taga T. Interleukin-6 family of cytokines and gp130. Blood 86 (1995) 1243-1254
    • (1995) Blood , vol.86 , pp. 1243-1254
    • Kishimoto, T.1    Akira, S.2    Narazaki, M.3    Taga, T.4
  • 28
    • 0036771556 scopus 로고    scopus 로고
    • Proinflammatory cytokines (TNFα/IL-1α) induction of human osteoclast formation
    • Kudo O., Fujikawa Y., Itonaga I., Sabokbar A., Torisu T., and Athanasou N.A. Proinflammatory cytokines (TNFα/IL-1α) induction of human osteoclast formation. J. Pathol. 198 (2002) 220-227
    • (2002) J. Pathol. , vol.198 , pp. 220-227
    • Kudo, O.1    Fujikawa, Y.2    Itonaga, I.3    Sabokbar, A.4    Torisu, T.5    Athanasou, N.A.6
  • 29
    • 0037265995 scopus 로고    scopus 로고
    • Interleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanism
    • Kudo O., Sabokbar A., Pocock A., Itonaga I., Fujikawa Y., and Athanasou N.A. Interleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanism. Bone 32 (2003) 1-7
    • (2003) Bone , vol.32 , pp. 1-7
    • Kudo, O.1    Sabokbar, A.2    Pocock, A.3    Itonaga, I.4    Fujikawa, Y.5    Athanasou, N.A.6
  • 30
    • 0036512435 scopus 로고    scopus 로고
    • Multiple myeloma: Evolving genetic events and host interactions
    • Kuehl W.M., and Bergsagel P.L. Multiple myeloma: Evolving genetic events and host interactions. Nature Rev. Cancer 1 (2002) 175-187
    • (2002) Nature Rev. Cancer , vol.1 , pp. 175-187
    • Kuehl, W.M.1    Bergsagel, P.L.2
  • 31
    • 0034677177 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the OPG/RANKL/RANK interaction
    • Kobayashi K., Takahashi N., Jimi E., Udagawa N., Takami M., and Kotake S. Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the OPG/RANKL/RANK interaction. J. Exp. Med. 191 (2000) 275-286
    • (2000) J. Exp. Med. , vol.191 , pp. 275-286
    • Kobayashi, K.1    Takahashi, N.2    Jimi, E.3    Udagawa, N.4    Takami, M.5    Kotake, S.6
  • 32
    • 0032540319 scopus 로고    scopus 로고
    • Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
    • Lacey D.L., Timms E., Tan H.L., Keller M., Dunstan C.R., and Burgess T. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93 (1998) 165-176
    • (1998) Cell , vol.93 , pp. 165-176
    • Lacey, D.L.1    Timms, E.2    Tan, H.L.3    Keller, M.4    Dunstan, C.R.5    Burgess, T.6
  • 33
    • 0034254432 scopus 로고    scopus 로고
    • Regulation of interleukin-6 gene expression by pro-inflammatory cytokines in a colon cancer cell line
    • Legrand-Poels S., Schoonbroodt S., and Piette J. Regulation of interleukin-6 gene expression by pro-inflammatory cytokines in a colon cancer cell line. Biochem. J. 349 (2000) 765-773
    • (2000) Biochem. J. , vol.349 , pp. 765-773
    • Legrand-Poels, S.1    Schoonbroodt, S.2    Piette, J.3
  • 36
    • 15444362701 scopus 로고    scopus 로고
    • 2 signaling system results in enhancement of osteoclastogenesis through effects on the OPG/RANKL/RANK system
    • 2 signaling system results in enhancement of osteoclastogenesis through effects on the OPG/RANKL/RANK system. Endocrinology 146 (2005) 1991-1998
    • (2005) Endocrinology , vol.146 , pp. 1991-1998
    • Liu, X.H.1    Kirshenbaum, A.2    Yao, S.3    Levine, A.C.4
  • 37
    • 0026339843 scopus 로고
    • Regulation of osteoblast proliferation by leukemia inhibitory factor
    • Lowe C., Cornish J., Callon K., Martin T.J., and Reid L.R. Regulation of osteoblast proliferation by leukemia inhibitory factor. J. Bone Miner. Res. 6 (1991) 1277-1283
    • (1991) J. Bone Miner. Res. , vol.6 , pp. 1277-1283
    • Lowe, C.1    Cornish, J.2    Callon, K.3    Martin, T.J.4    Reid, L.R.5
  • 38
    • 0024404268 scopus 로고
    • Parathyroid hormone (PTH) and PTH- like protein (PLP) stimulate interleukin-6 production by osteogenic cells: A possible role of interleukin-6 in osteoclastogenesis
    • Lowik C.W., van der Pluijm G., Bloys H., Hoekman K., Bijvoet O.L.M., Aarden L.A., and Papapoulos S.A. Parathyroid hormone (PTH) and PTH- like protein (PLP) stimulate interleukin-6 production by osteogenic cells: A possible role of interleukin-6 in osteoclastogenesis. Biochem. Biophys. Res. Commun. 162 (1989) 1546-1552
    • (1989) Biochem. Biophys. Res. Commun. , vol.162 , pp. 1546-1552
    • Lowik, C.W.1    van der Pluijm, G.2    Bloys, H.3    Hoekman, K.4    Bijvoet, O.L.M.5    Aarden, L.A.6    Papapoulos, S.A.7
  • 39
    • 0025875857 scopus 로고
    • Interleukin-6 is a prognostic factor in multiple myeloma
    • Ludwig H., Nachbaur D.M., Fritz E., Krainer M., and Huber H. Interleukin-6 is a prognostic factor in multiple myeloma. Blood 77 (1991) 2794-2795
    • (1991) Blood , vol.77 , pp. 2794-2795
    • Ludwig, H.1    Nachbaur, D.M.2    Fritz, E.3    Krainer, M.4    Huber, H.5
  • 41
    • 0032077461 scopus 로고    scopus 로고
    • The role of IL-6 type cytokines and their receptors in bone
    • Manolagas S.C. The role of IL-6 type cytokines and their receptors in bone. Ann. N. Y. Acad. Sci. 840 (1998) 194-204
    • (1998) Ann. N. Y. Acad. Sci. , vol.840 , pp. 194-204
    • Manolagas, S.C.1
  • 42
    • 0028925088 scopus 로고
    • Bone marrow, cytokines, and bone remodeling: Emerging insights into the pathophysiology of osteoprosis
    • Manolagas S.C., and Jilka R.L. Bone marrow, cytokines, and bone remodeling: Emerging insights into the pathophysiology of osteoprosis. N. Engl. J. Med. 332 (1995) 305
    • (1995) N. Engl. J. Med. , vol.332 , pp. 305
    • Manolagas, S.C.1    Jilka, R.L.2
  • 45
    • 0343474047 scopus 로고
    • Fatal syndrome in mice engrafted with cells producing high levels of the leukemia inhibitory factor
    • Metcalf D., and Gearing G.P. Fatal syndrome in mice engrafted with cells producing high levels of the leukemia inhibitory factor. Proc. Natl. Acad. Sci. USA 86 (1989) 5948-5952
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 5948-5952
    • Metcalf, D.1    Gearing, G.P.2
  • 48
    • 0034618580 scopus 로고    scopus 로고
    • Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-κB ligand: Modulation of the expression by osteotropic factors and cytokines
    • Nakashima T., Kobayashi Y., Yamasaki S., Kawakami A., Eguchi K., Sasaki H., and Sakai H. Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-κB ligand: Modulation of the expression by osteotropic factors and cytokines. Biochem. Biophys. Res. Commun. 275 (2000) 768-775
    • (2000) Biochem. Biophys. Res. Commun. , vol.275 , pp. 768-775
    • Nakashima, T.1    Kobayashi, Y.2    Yamasaki, S.3    Kawakami, A.4    Eguchi, K.5    Sasaki, H.6    Sakai, H.7
  • 49
    • 0034163461 scopus 로고    scopus 로고
    • Inhibition of constitutively activated Stat-3 signaling pathway suppresses growth of prostate cancer cells
    • Ni Z., Lou W., Leman E.S., and Gao A.C. Inhibition of constitutively activated Stat-3 signaling pathway suppresses growth of prostate cancer cells. Cancer Res. 60 (2000) 1225-1228
    • (2000) Cancer Res. , vol.60 , pp. 1225-1228
    • Ni, Z.1    Lou, W.2    Leman, E.S.3    Gao, A.C.4
  • 50
    • 0033785491 scopus 로고    scopus 로고
    • Expression levels of gp130 in bone marrow stromal cells determine the magnitude of osteo-clastogenic signals generated by IL-6-type cytokines
    • O'Brien C.A., Lin S.C., Bellido T., and Manolagas S.C. Expression levels of gp130 in bone marrow stromal cells determine the magnitude of osteo-clastogenic signals generated by IL-6-type cytokines. J. Cell. Biochem. 79 (2000) 532-549
    • (2000) J. Cell. Biochem. , vol.79 , pp. 532-549
    • O'Brien, C.A.1    Lin, S.C.2    Bellido, T.3    Manolagas, S.C.4
  • 53
    • 0036241535 scopus 로고    scopus 로고
    • Involvement of cyclooxygenase-2 in osteoclast formation and bone destruction in bone metastasis of mammary carcinoma cell lines
    • Ono K., Akatsu T., Murakami T., Kitamura R., Yamamoto M., Rokutanda M., Nagata N., and Kugai N. Involvement of cyclooxygenase-2 in osteoclast formation and bone destruction in bone metastasis of mammary carcinoma cell lines. J. Bone Miner. Res. 17 (2002) 774-781
    • (2002) J. Bone Miner. Res. , vol.17 , pp. 774-781
    • Ono, K.1    Akatsu, T.2    Murakami, T.3    Kitamura, R.4    Yamamoto, M.5    Rokutanda, M.6    Nagata, N.7    Kugai, N.8
  • 54
    • 0025990964 scopus 로고
    • The effects of interleukin-6 and interleukin-3 on early hemotopoietic events in long-term cultures of human bone marrow
    • Otsuka T., Thacker J.D., and Hogge D.E. The effects of interleukin-6 and interleukin-3 on early hemotopoietic events in long-term cultures of human bone marrow. Exp. Hematol. 19 (1991) 1042-1048
    • (1991) Exp. Hematol. , vol.19 , pp. 1042-1048
    • Otsuka, T.1    Thacker, J.D.2    Hogge, D.E.3
  • 56
    • 0036720502 scopus 로고    scopus 로고
    • Cytokines synergistically induce osteoclast differentiation: Support by immortalized or normal calvarial cells
    • Ragab A.A., Nalepka J.L., Bi Y., and Greenfield E.M. Cytokines synergistically induce osteoclast differentiation: Support by immortalized or normal calvarial cells. Am. J. Physiol. Cell Physiol. 283 (2002) C679-C687
    • (2002) Am. J. Physiol. Cell Physiol. , vol.283
    • Ragab, A.A.1    Nalepka, J.L.2    Bi, Y.3    Greenfield, E.M.4
  • 57
    • 0029837583 scopus 로고    scopus 로고
    • Advances in bone biology: The osteoclast
    • Roodman G.D. Advances in bone biology: The osteoclast. Endocr. Rev. 17 (1996) 308-332
    • (1996) Endocr. Rev. , vol.17 , pp. 308-332
    • Roodman, G.D.1
  • 58
    • 0034042227 scopus 로고    scopus 로고
    • IL-6 modulates trabecular and endochondral bone turnover in the nude mouse by stimulating osteoclast differentiation
    • Rozen N., Ish-Shalom S., Rachmiel A., Stein H., and Lewinson D. IL-6 modulates trabecular and endochondral bone turnover in the nude mouse by stimulating osteoclast differentiation. Bone 26 (2000) 469-474
    • (2000) Bone , vol.26 , pp. 469-474
    • Rozen, N.1    Ish-Shalom, S.2    Rachmiel, A.3    Stein, H.4    Lewinson, D.5
  • 59
    • 0031005576 scopus 로고    scopus 로고
    • OPG: A novel secreted protein involved in the regulation of bone density
    • Simonet W.S., and Luthy R. OPG: A novel secreted protein involved in the regulation of bone density. Cell 89 (1997) 309-319
    • (1997) Cell , vol.89 , pp. 309-319
    • Simonet, W.S.1    Luthy, R.2
  • 61
    • 0028931604 scopus 로고
    • Choice of STATs and other substrates specified by modular tyrosin-based motifs in cytokine receptors
    • Stahl N., Farruggella T.J., Boulton T.G., Zhong Z., Darnell Jr. J.E., and Yancopoulos G.D. Choice of STATs and other substrates specified by modular tyrosin-based motifs in cytokine receptors. Science 267 (1995) 1349-1353
    • (1995) Science , vol.267 , pp. 1349-1353
    • Stahl, N.1    Farruggella, T.J.2    Boulton, T.G.3    Zhong, Z.4    Darnell Jr., J.E.5    Yancopoulos, G.D.6
  • 63
    • 0033304730 scopus 로고    scopus 로고
    • Modulation of osteoclast differentiation and function by the new members of the TNF receptor and ligand families
    • Suda T., Takahashi N., Udagawa E., Jimi M.T., and Martin T.J. Modulation of osteoclast differentiation and function by the new members of the TNF receptor and ligand families. Endocr. Rev. 20 (1999) 345-357
    • (1999) Endocr. Rev. , vol.20 , pp. 345-357
    • Suda, T.1    Takahashi, N.2    Udagawa, E.3    Jimi, M.T.4    Martin, T.J.5
  • 64
    • 0035069304 scopus 로고    scopus 로고
    • 2 in periarticular osteoporosis of postmenopausal woman with rheumatoid arthritis
    • 2 in periarticular osteoporosis of postmenopausal woman with rheumatoid arthritis. J. Bone Miner. Metab. 19 (2001) 89-96
    • (2001) J. Bone Miner. Metab. , vol.19 , pp. 89-96
    • Sugiyama, T.1
  • 65
    • 0031975973 scopus 로고    scopus 로고
    • 2 on bone mass in rat long bones and calvariae
    • 2 on bone mass in rat long bones and calvariae. J. Endocrinol. 156 (1998) 51-57
    • (1998) J. Endocrinol. , vol.156 , pp. 51-57
    • Suponitzky, I.1    Weinreb, M.2
  • 66
    • 0030890718 scopus 로고    scopus 로고
    • gp130 and the interleukin 6 family of cytokines
    • Taga T., and Kishimoto T. gp130 and the interleukin 6 family of cytokines. Annu. Rev. Immunol. 15 (1997) 797-819
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 797-819
    • Taga, T.1    Kishimoto, T.2
  • 70
    • 0032698230 scopus 로고    scopus 로고
    • Flow cytometric determination of interleukin-1β, interleukin-6 and tumor necrosis factor-α in monocytes of rheumatoid arthritis patients: Relation with parameters of osteoporosis
    • Verbruggen A., De Clerck L.S., Bridts C.H., van Offel J.F., and Stevens W.J. Flow cytometric determination of interleukin-1β, interleukin-6 and tumor necrosis factor-α in monocytes of rheumatoid arthritis patients: Relation with parameters of osteoporosis. Cytokines 11 (1999) 869-874
    • (1999) Cytokines , vol.11 , pp. 869-874
    • Verbruggen, A.1    De Clerck, L.S.2    Bridts, C.H.3    van Offel, J.F.4    Stevens, W.J.5
  • 73
    • 0036259278 scopus 로고    scopus 로고
    • Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair
    • Zhang X., Schwarz E.M., Young D.A., Puzas J., Rosier R.N., and O'Keefe R.J. Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. J. Clin. Invest. 109 (2002) 1405-1415
    • (2002) J. Clin. Invest. , vol.109 , pp. 1405-1415
    • Zhang, X.1    Schwarz, E.M.2    Young, D.A.3    Puzas, J.4    Rosier, R.N.5    O'Keefe, R.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.