Propionyl-L-carnitine reduces proliferation and potentiates bax-related apoptosis of aortic intimal smooth muscle cells by modulating nuclear factor-κB activity

Journal of Biological Chemistry

Volumn 282, Issue 7, 2007, Pages 4932-4942

  Orlandi, Augusto ^a   Francesconi, Arianna ^a   Marcellini, Marcella ^b   Di Lascio, Antonio ^a   Spagnoli, Luigi Giusto ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b Sigma Tau SpA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; ENZYME ACTIVITY; ENZYME INHIBITION; MUSCLE; NUCLEOTIDES;

CELL APOPTOSIS; PROPIONYL-L-CARNITINE (PLC); RABBITS; SMOOTH MUSCLE CELLS (SMC);

CELL DEATH;

ANTISENSE OLIGODEOXYNUCLEOTIDE; CYTOCHROME C; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; INHIBITOR OF APOPTOSIS PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; PROPIONYLCARNITINE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P50; SN 50; SURVIVIN; SYNAPTOTAGMIN I; VASCULAR CELL ADHESION MOLECULE 1; BAX PROTEIN, RAT; CARDIOTONIC AGENT; CARNITINE; DRUG DERIVATIVE; MUSCLE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA INTIMA; APOPTOSIS; ARTERY INJURY; ARTERY INTIMA PROLIFERATION; ARTICLE; BIOAVAILABILITY; CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; IN VIVO STUDY; MALE; MODULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; RAT; SERUM; SMOOTH MUSCLE FIBER; UPREGULATION; ANIMAL; AORTA; DRUG EFFECT; INJURY; INTIMA; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; RABBIT; WISTAR RAT;

ORYCTOLAGUS CUNICULUS; RATTUS;

ANIMALS; AORTA; APOPTOSIS; BASE SEQUENCE; BCL-2-ASSOCIATED X PROTEIN; CARDIOTONIC AGENTS; CARNITINE; DOSE-RESPONSE RELATIONSHIP, DRUG; G1 PHASE; MALE; MOLECULAR SEQUENCE DATA; MUSCLE PROTEINS; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; RABBITS; RATS; RATS, WISTAR; S PHASE; TUNICA INTIMA; UP-REGULATION;

EID: 33947531762     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M606148200     Document Type: Article

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