메뉴 건너뛰기




Volumn 9, Issue 3, 1998, Pages 216-222

L-propionyl carnitine, an endogenous ester in fatty acid metabolism, exerts anti-shock and endothelial protective effects in rat splanchnic ischemia-reperfusion injury

Author keywords

[No Author keywords available]

Indexed keywords

CARNITINE; DRUG DERIVATIVE; FATTY ACID; PEROXIDASE; PROPIONYLCARNITINE;

EID: 0032014455     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199803000-00010     Document Type: Article
Times cited : (20)

References (32)
  • 1
    • 0014873340 scopus 로고
    • Role of lysosomes in the pathogenesis of splanchnic ischemia shock in cats
    • Glenn TM, Lefer AM: Role of lysosomes in the pathogenesis of splanchnic ischemia shock in cats. Circ Res 27:783-797, 1970.
    • (1970) Circ Res , vol.27 , pp. 783-797
    • Glenn, T.M.1    Lefer, A.M.2
  • 2
    • 0018352482 scopus 로고
    • Early phase of jejunal regeneration after short term ischemia in the rat
    • Menge H, Robinson JW: Early phase of jejunal regeneration after short term ischemia in the rat. Lab Invest 40:25-30, 1979.
    • (1979) Lab Invest , vol.40 , pp. 25-30
    • Menge, H.1    Robinson, J.W.2
  • 3
    • 0018069968 scopus 로고
    • Intestinal ischemia and shock factors
    • Haglund U, Lundgren O: Intestinal ischemia and shock factors. Fed Proc 37:2729-2733, 1978.
    • (1978) Fed Proc , vol.37 , pp. 2729-2733
    • Haglund, U.1    Lundgren, O.2
  • 4
    • 0025358131 scopus 로고
    • Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat
    • Colletti LM, Remick DG, Burtch GD, Kunkel SL, Strieter RM, Campbell DA Jr.: Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat. J Clin Invest 85:1936-1943, 1990.
    • (1990) J Clin Invest , vol.85 , pp. 1936-1943
    • Colletti, L.M.1    Remick, D.G.2    Burtch, G.D.3    Kunkel, S.L.4    Strieter, R.M.5    Campbell D.A., Jr.6
  • 5
    • 0025823153 scopus 로고
    • Beneficial effects of transforming growth factor-beta and tissue plasminogen activator in splanchnic artery occlusion and reperfusion in cats
    • Karasawa A, Guo JP, Ma XL, Lefer AM: Beneficial effects of transforming growth factor-beta and tissue plasminogen activator in splanchnic artery occlusion and reperfusion in cats. J Cardiovasc Pharm 18:95-105, 1991.
    • (1991) J Cardiovasc Pharm , vol.18 , pp. 95-105
    • Karasawa, A.1    Guo, J.P.2    Ma, X.L.3    Lefer, A.M.4
  • 6
    • 0025819503 scopus 로고
    • Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia
    • Lefer AM, Tsao PS, Lefer DJ, Ma XL: Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia. FASEB J 5:2029-2034, 1991.
    • (1991) FASEB J , vol.5 , pp. 2029-2034
    • Lefer, A.M.1    Tsao, P.S.2    Lefer, D.J.3    Ma, X.L.4
  • 7
    • 0023270343 scopus 로고
    • The primary localization of free radical generation after anoxia/reoxygenation in isolated endothelial cells
    • Ratych RE, Chuknyiska RS, Bulkley GB: The primary localization of free radical generation after anoxia/reoxygenation in isolated endothelial cells. Surgery 102:122-131, 1987.
    • (1987) Surgery , vol.102 , pp. 122-131
    • Ratych, R.E.1    Chuknyiska, R.S.2    Bulkley, G.B.3
  • 8
    • 0025542037 scopus 로고
    • Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat
    • Tsao PS, Aoki N, Lefer DJ, Johnson G, Lefer AM: Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat. Circulation 82:1402-1412, 1990.
    • (1990) Circulation , vol.82 , pp. 1402-1412
    • Tsao, P.S.1    Aoki, N.2    Lefer, D.J.3    Johnson, G.4    Lefer, A.M.5
  • 9
    • 0023810631 scopus 로고
    • Anti-shock effects of human superoxide dismutase in splanchnic artery occlusion (SAO) shock
    • Bitterman H, Aoki N, Lefer AM: Anti-shock effects of human superoxide dismutase in splanchnic artery occlusion (SAO) shock. Proc Soc Expe Med 188:265-271, 1988.
    • (1988) Proc Soc Expe Med , vol.188 , pp. 265-271
    • Bitterman, H.1    Aoki, N.2    Lefer, A.M.3
  • 10
    • 0023713495 scopus 로고
    • Activated neutrophils release mediators that may contribute to myocardial injury and dysfunction associated with ischemia and reperfusion
    • Mullane KM, Westlin W, Kraemer R: Activated neutrophils release mediators that may contribute to myocardial injury and dysfunction associated with ischemia and reperfusion. Ann NY Acad Sci 524:103-121, 1988.
    • (1988) Ann NY Acad Sci , vol.524 , pp. 103-121
    • Mullane, K.M.1    Westlin, W.2    Kraemer, R.3
  • 12
    • 0025944580 scopus 로고
    • Protective actions of a leukotriene B4 antagonist in splanchnic ischemia and reperfusion in rats
    • Karasawa A, Guo JP, Ma XL, Tsao PS, Lefer AM: Protective actions of a leukotriene B4 antagonist in splanchnic ischemia and reperfusion in rats. Am J Physiol 261:G191-G198, 1991.
    • (1991) Am J Physiol , vol.261
    • Karasawa, A.1    Guo, J.P.2    Ma, X.L.3    Tsao, P.S.4    Lefer, A.M.5
  • 13
    • 0021024932 scopus 로고
    • Carnitine-metabolism and functions
    • Bremer J: Carnitine-metabolism and functions. Physiol Rev 63:1420-1480, 1983.
    • (1983) Physiol Rev , vol.63 , pp. 1420-1480
    • Bremer, J.1
  • 14
    • 0024403884 scopus 로고
    • Protective effect of propionyl-L-carnitine against ischaemia and reperfusion-damage
    • Ferrari R, Ceconi C, Curello S, Pasini E, Visioli O: Protective effect of propionyl-L-carnitine against ischaemia and reperfusion-damage. Mol Cell Biochem 88:161-168, 1989.
    • (1989) Mol Cell Biochem , vol.88 , pp. 161-168
    • Ferrari, R.1    Ceconi, C.2    Curello, S.3    Pasini, E.4    Visioli, O.5
  • 16
    • 0026783181 scopus 로고
    • Antiradical effects in L-propionyl carnitine protection of the heart against ischemia-reperfusion injury: The possible role of iron chelation
    • Reznick AZ, Kagan VE, Ramsey R, Tsuchiya M, Khwaja S, Serbinova EA: Antiradical effects in L-propionyl carnitine protection of the heart against ischemia-reperfusion injury: The possible role of iron chelation. Arch Biochem Biophy 296:394-401, 1992.
    • (1992) Arch Biochem Biophy , vol.296 , pp. 394-401
    • Reznick, A.Z.1    Kagan, V.E.2    Ramsey, R.3    Tsuchiya, M.4    Khwaja, S.5    Serbinova, E.A.6
  • 17
    • 0027448606 scopus 로고
    • Protective role of propionyl carnitine in vascular disorders experimentally induced by endothelin (ET-1) serotonin and K-carrageenin
    • Bertelli A, Giovannini L, Galmozzi G, Bertelli AA: Protective role of propionyl carnitine in vascular disorders experimentally induced by endothelin (ET-1) serotonin and K-carrageenin. Drugs Exp Clin Res 19:7-11, 1993.
    • (1993) Drugs Exp Clin Res , vol.19 , pp. 7-11
    • Bertelli, A.1    Giovannini, L.2    Galmozzi, G.3    Bertelli, A.A.4
  • 20
    • 0020051148 scopus 로고
    • Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker
    • Bradley PP, Priebat DA, Christensen RD, Rothstein G: Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker. J Invest Dermatol 78:206-209, 1982.
    • (1982) J Invest Dermatol , vol.78 , pp. 206-209
    • Bradley, P.P.1    Priebat, D.A.2    Christensen, R.D.3    Rothstein, G.4
  • 21
    • 0021998590 scopus 로고
    • Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium
    • Mullane KM, Kraemer R, Smith B: Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. J Pharmacol Methods 14:157-167, 1985.
    • (1985) J Pharmacol Methods , vol.14 , pp. 157-167
    • Mullane, K.M.1    Kraemer, R.2    Smith, B.3
  • 22
    • 0027052682 scopus 로고
    • Inhibition of histamine release and pressure increase induced by endothelin (ET-1) in isolated rat kidneys treated with propionyl carnitine
    • Bertelli A, Giovannini L, Bertelli AA: Inhibition of histamine release and pressure increase induced by endothelin (ET-1) in isolated rat kidneys treated with propionyl carnitine. Drugs Under Exp Clin Res 18:349-353, 1992.
    • (1992) Drugs under Exp Clin Res , vol.18 , pp. 349-353
    • Bertelli, A.1    Giovannini, L.2    Bertelli, A.A.3
  • 23
    • 0027496497 scopus 로고
    • Vulnerability of vascular endothelium in lipopolysaccharide toxicity: Effect of (Acyl) carnitine on endothelial stability
    • Hulsmann WC: Vulnerability of vascular endothelium in lipopolysaccharide toxicity: Effect of (Acyl) carnitine on endothelial stability. Mediators Inflamm 2:S21-S23, 1993.
    • (1993) Mediators Inflamm , vol.2
    • Hulsmann, W.C.1
  • 24
    • 0030101681 scopus 로고    scopus 로고
    • Endotoxin-induced oxidative stress in the rat small intestine: Role of nitric oxide
    • Chamulitrat W, Skrepnik NV, Spitzer JJ: Endotoxin-induced oxidative stress in the rat small intestine: Role of nitric oxide. Shock 5:217-222, 1996.
    • (1996) Shock , vol.5 , pp. 217-222
    • Chamulitrat, W.1    Skrepnik, N.V.2    Spitzer, J.J.3
  • 25
    • 0025895541 scopus 로고
    • Free radical scavenging is involved in the protective effect of L-propionyl-carnitine against ischemia-reperfusion injury of the heart
    • Packer L, Valenza M, SerbinovaE, Starke-Reed P, Frost K, Kagan V: Free radical scavenging is involved in the protective effect of L-propionyl-carnitine against ischemia-reperfusion injury of the heart. Arch Biochem Biophys 288:533-537, 1991.
    • (1991) Arch Biochem Biophys , vol.288 , pp. 533-537
    • Packer, L.1    Valenza, M.2    SerbinovaE3    Starke-Reed, P.4    Frost, K.5    Kagan, V.6
  • 26
    • 0022975637 scopus 로고
    • Effect of L-carnitine on human neutrophil activity
    • Schinetti ML, Mazzini A: Effect of L-carnitine on human neutrophil activity. Int J Tiss React 8:199-203, 1986.
    • (1986) Int J Tiss React , vol.8 , pp. 199-203
    • Schinetti, M.L.1    Mazzini, A.2
  • 27
    • 0026342111 scopus 로고
    • Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity
    • Butcher EC: Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity. Cell 67:1033-1036, 1991.
    • (1991) Cell , vol.67 , pp. 1033-1036
    • Butcher, E.C.1
  • 28
    • 0026445853 scopus 로고
    • L-selectin function is required for beta 2-integrin-mediated neutrophil adhesion at physiological shear rates in vivo
    • Von Andrian UH, Hansell P, Chambers JD, Berger EM, Torres Filho I, Arfors KE: L-selectin function is required for beta 2-integrin-mediated neutrophil adhesion at physiological shear rates in vivo. Am J Physiol 263:H1034-H1044, 1992.
    • (1992) Am J Physiol , vol.263
    • Von Andrian, U.H.1    Hansell, P.2    Chambers, J.D.3    Berger, E.M.4    Torres Filho, I.5    Arfors, K.E.6
  • 31
    • 0027998962 scopus 로고
    • Protection of beta-thalassaemic erythrocytes from oxidative stress by propionyl carnitine
    • Palmieri L, Ronca F, Malengo S, Bertelli A: Protection of beta-thalassaemic erythrocytes from oxidative stress by propionyl carnitine. Int J Tiss Reac 16:121-129, 1994.
    • (1994) Int J Tiss Reac , vol.16 , pp. 121-129
    • Palmieri, L.1    Ronca, F.2    Malengo, S.3    Bertelli, A.4
  • 32
    • 0028051497 scopus 로고
    • L-propionyl carnitine protects erythrocytes and low density lipoproteins against peroxidation
    • Bertelli A, Conte A, Ronca G: L-propionyl carnitine protects erythrocytes and low density lipoproteins against peroxidation. Drugs Under Exp Clin Res 20:191-197, 1994.
    • (1994) Drugs under Exp Clin Res , vol.20 , pp. 191-197
    • Bertelli, A.1    Conte, A.2    Ronca, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.