The NF-κB and IκB system in injured arteries

Pathobiology

Volumn 66, Issue 6, 1998, Pages 311-320

  Lindner, Volkhard ^a  

^a MAINE MEDICAL CENTER   (United States)

Author keywords

Arterial denudation; Endothelium; I B ; I B ; Inflammation; MCP 1; p50; p65; Smooth muscle; VCAM 1

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; VASCULAR CELL ADHESION MOLECULE 1; DNA BINDING PROTEIN; I KAPPA B; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; ONCOPROTEIN; TRANSCRIPTION FACTOR REL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY INJURY; ARTICLE; BALLOON CATHETER; CAROTID ARTERY; CELL ADHESION; CONTROLLED STUDY; ENDOTHELIUM CELL; GEL MOBILITY SHIFT ASSAY; IMMUNOBLOTTING; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; ANIMAL; CAROTID ARTERY INJURY; COMMON CAROTID ARTERY; DISEASE MODEL; DNA PROBE; GENE EXPRESSION; GENETICS; INJURY; MACROPHAGE; METABOLISM; MONOCYTE; NUCLEOTIDE SEQUENCE; PATHOLOGY; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

ANIMALIA;

ANIMALS; BASE SEQUENCE; CAROTID ARTERY INJURIES; CAROTID ARTERY, COMMON; CELL ADHESION; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; DNA PROBES; DNA-BINDING PROTEINS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION; I-KAPPA B PROTEINS; MACROPHAGES; MICE; MONOCYTES; MUSCLE, SMOOTH, VASCULAR; NF-KAPPA B; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-REL; RATS; RATS, SPRAGUE-DAWLEY; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0031594962     PISSN: 10152008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000028039     Document Type: Article

References (33)

1. Baeuerle PA, Baltimore D: NF-κB: Ten years after. Cell 1996;87:13-20.
2. Kopp EB, Ghosh S: NF-κB and Rel proteins in innate immunity. Adv Immunol 1995;58:1-27.
3. Siebenlist U, Franzoso G, Brown K: Structure, regulation and function of NF-κB. Annu Rev Cell Biol 1994;10:405-455.
4. Collins T, Palmer HJ, Whitley MZ, Neish AS, Williams AJ: A common theme in endothelial activation: Insights from the structural analysis of the genes for E-selectin and VCAM-1. Trends Cardiovasc Med 1993;3:92-97.
5. Grilli M, Chiu JJ-S, Leonardo JM: NF-κB and Rel. Panicipants in a multiform transcriptional regulatory system. Int Rev Cytol 1993;143:1-62.
6. Finco TS, Baldwin AS: Mechanistic aspects of NF-κB regulation: The emerging role of phosphorylation and proteolysis. Immunity 1995;3:263-272.
7. Scott ML, Fujita T, Liou H-C, Nolan GP, Baltimore D. The p65 subunit of NF-κB regulates IκB by two distinct mechanism. Genes Dev 1993;7:1266-1276.
8. Liou H-C, Baltimore D: Regulation of NF-κb/rel transcription factor and IκB inhibitor system. Curr Opin Cell Biol 1993;5:477-487.
9. Read MA, Whitley MZ, Williams AJ, Collins T: NF-kappaB and IkappaBα: An inducible regulatory system in endothelial activation. J Exp Med 1994;179:503-512.
10. Obata H, Biro S, Arima N, Kaieda H, Kihara T, Eto H, Miyata M, Tanaka H: NF-kappaB is induced in the nuclei of cultured rat aortic smooth muscle cells by stimulation of various growth factors. Biochem Biophys Res Commun 1996;224:27-32.
11. Lawrence R, Chang L-J, Siebenlist U, Bressler P, Sonenshein GE: Vascular smooth muscle cells express a constitutive NF-kappaB-like activity J Biol Chem 1994;269:28913-28918.
12. Nakajima T, Kitajima I, Shin H, Takasaki I, Shigeta K, Abeyama K, Yamashita Y, Tokioka T, Soejima Y, Maruyama I: Involvement of NF-kappaB activation in thrombin-induced human vascular smooth muscle cell proliferation. Biochem Biophys Res Commun 1994;204:950-955.
13. Quarnström EE, Ostberg CO, Turk GL, Richardson CA, Bomsztyk K: Fibronectin attachment activates the NF-κB p50/p65 heterodimer in fibroblasts and smooth muscle cells. J Biol Chem 1994;269:30765-30768.
14. Bellas RE, Lee JS, Sonenshein GE: Expression of a constitute e NF-κB-hke activity is essential for proliferation of cultured bovine vascular smooth muscle cells. J Clin Invest 1995;96:2521-2527.
15. Shin WS, Hong Y-H, Peng H-B, De Caterina R, Libby P, Liao JK: Nitric oxide attenuates vascular smooth muscle cell activation by interferon-γ. J Biol Chem 1996;271:11317-11324.
16. Brand K, Page S, Rogler G, Bartsch A, Brandl R, Knuechel R, Page M, Kaltschmidt C, Baeuerle P, Neumeier D: Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion. J Clin Invest 1996;97:1715-1722.
17. Clowes AW, Reidy MA, Clowes MM: Kinetics of cellular proliferation after arterial injury. I. Smooth muscle growth in the absence of endothelium. Lab Invest 1983;49:327-333.
18. Lindner V: Expression of platelet-derived growth factor ligands and receptors by rat aortic endothelium in vivo. Pathobiology 1996;63:257-264.
19. Lindner V, Fingerle J, Reidy MA: Mouse model of arterial injury. Circ Res 1993;73:792-796.
20. Yoshimura T, Takeya M, Takahashi K: Molecular cloning of rat monocyte chemoattractant protein-1 (MCP-1) and its expression in rat spleen cells and tumor cell lines. Biochem Biophys Res Commun 1991;174:504-509.
21. Williams AJ, Atkins RC, Fries JWU, Gimbrone MA Jr, Cybulsky MI, Collins T: Nucleotide sequence of rat vascular cell adhesion molecule-1 cDNA. Biochim Biophys Acta 1992;1131:214-216.
22. Tewari M, Dobrzanski P, Mohn K, Cressman KE, Hus J-C, Bravo R, Taub R: Rapid induction in regenerating liver of RL/IF-1 (and IκB thai inhibits NF-κB. RelB-p50, and c-Rel-p50) and PHF, a novel KB site-binding complex. Mol Cell Biol 1992;12:2898-2908.
23. Lindner V, Reidy MA: Expression of basic fibroblast growth factor and its receptor by smooth muscle cells and endothelium in injured rat arteries. An en face study. Circ Res 1993;73:589-595.
24. Sen R, Baltimore D: Multiple nuclear factors interact with the immunoglobulin enhancer sequence. Cell 1986;46:705-716.
25. Neish AS, Read MA, Thanos D, Pine R, Maniatis T, Collins T: Endothelial interferera regulatory factor 1 cooperates with NF-kappaB as a transcriptional activator of vascular cell adhesion molecule 1. Mol Cell Biol 1995;15:2558-2569.
26. Neish AS, Williams AJ, Palmer HJ, Whitley MZ, Collins T: Functional analysis of the human vascular cell adhesion molecule 1 promoter. J Exp Med 1992;176:1583-1593.
27. Freter RR, Alberta JA, Hwang GY, Wrentmore AL, Stiles CD: Platelet-derived growth factor induction of the immediate-early gene MCP-1 is mediated by NF-kappaB and a 90-kDa phosphoprotein coactivator. J Biol Chem 1996;271:17417-17424.
28. Li H, Cybulsky MI, Gimbrone MA Jr, Libby P: Inducible expression of vascular cell adhesion molecule-1 by vascular smooth muscle cells in vitro and within rabbit atheroma. Am J Pathol 1993;143:1551-1559.
29. Taubman MB, Rollins BJ, Poon M, Marmur J, Green RS, Berk BC, Nadal-Ginard B: JE mRNA accumulates rapidly in aortic injury and in platelet-derived growth factor-stimulated vascular smooth muscle cells. Circ Res 1992;70:314-325.
30. Lindner V, Collins T: Expression of KF-kappaB and IkappaB-α by aortic endothelium in an arterial injury model. Am J Pathol 1996;148:427-438.
31. Perkins ND, Felzien LK, Betts JC, Leung KY, Beach DH, Nabel GJ: Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactrvator. Science 1997;275:523-527
32. Fingerle J, Au YP, Clowes AW, Reidy MA: Intimal lesion formation in rat carotid arteries after endothelial denudation in absence of medial injury. Arteriosclerosis 1990;10:1082-1087.
33. Majesky MW, Schwartz SM, Clowes MM, Clowes AW: Heparin regulates smooth muscle S phase entry in the injured rat carotid artery. Circ Res 1987;61:296-300.