Immunosuppressive properties of the pigmented epithelial cells and the subretinal space

Chemical Immunology and Allergy

Volumn 92, Issue , 2007, Pages 86-93

  Zamiri, Parisa ^a   Sugita, Sunao ^a   Streilein, J Wayne ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD86 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; FAS LIGAND; GAMMA INTERFERON; HISTOCOMPATIBILITY ANTIGEN; PIGMENT EPITHELIUM DERIVED FACTOR; PROSTAGLANDIN E2; SOMATOSTATIN; THROMBOSPONDIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; THROMBOSPONDIN 1;

ANTERIOR EYE CHAMBER; ANTIGEN EXPRESSION; ARTICLE; BLOOD RETINA BARRIER; CELL FUNCTION; CELLULAR DISTRIBUTION; CILIARY BODY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; HUMAN; IMMUNE DEFICIENCY; IMMUNOLOGY; IMMUNOMODULATION; IMMUNOREGULATION; IRIS; LYMPHOCYTE PROLIFERATION; NONHUMAN; ORGAN TRANSPLANTATION; PIGMENT CELL; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; RETINA MACULA AGE RELATED DEGENERATION; RETINA TRANSPLANTATION; RETINITIS; T LYMPHOCYTE; ANIMAL; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE ACTIVATION; PHYSIOLOGY; REVIEW;

ANIMALS; HUMANS; IMMUNE TOLERANCE; LYMPHOCYTE ACTIVATION; PIGMENT EPITHELIUM OF EYE; T-LYMPHOCYTES; THROMBOSPONDIN 1; TRANSFORMING GROWTH FACTOR BETA;

EID: 33947502543     PISSN: 16602242     EISSN: None     Source Type: Book Series    
DOI: 10.1159/000099259     Document Type: Article

References (48)

1. Jiang LQ, Jorquera M, Streilein JW: Subretinal space and vitreous cavity as immunologically privileged sites for retinal allografts. Invest Ophthalmol Vis Sci 1993;34:3347-3354.
2. Jiang LQ, Jorquera M, Streilein JW: Immunologic consequences of intraocular implantation of retinal pigment epithelial allografts. Exp Eye Res 1994;58:719-728.
3. Jiang LQ, Streilein JW: Immune privilege extended to allogeneic tumor cells in the vitreous cavity. invest Ophthalmol Vis Sci 1991;32:224-228.
4. Sonoda KH, Sakamoto T, Qiao H, Hisatomi T, Oshima T, Tsutsumi-Miyahara C, Exley M, Balk SP, Taniguchi M, Ishibashi T: The analysis of systemic tolerance elicited by antigen inoculation into the vitreous cavity: vitreous cavity-associated immune deviation. Immunology 2005;116: 390-399.
5. Wenkel H, Chen PW, Ksander BR, Streilein JW: Immune privilege is extended, then withdrawn, from allogeneic tumor cell grafts placed in the subretinal space. Invest Ophthalmol Vis Sci 1999;40:3202-3208.
6. Wenkel H, Streilein JW: Analysis of immune deviation elicited by antigens injected into the subretinal space. Invest Ophthalmol Vis Sci 1998;39:1823-1834.
7. Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB, Ferris FL, Ott J, Barnstable C, Hoh J: Complement factor H polymorphism in age-related macular degeneration. Science 2005;308:385-389.
8. Edwards AO, Ritter R 3rd, Abel KJ, Manning A, Panhuysen C, Farrer LA: Complement factor H polymorphism and age-related macular degeneration. Science 2005;308:421-424.
9. Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, Gallins P, Spencer KL, Kwan SY, Noureddine M, Gilbert JR, Schnetz-Boutaud N, Agarwal A, Postel EA, Pericak-Vance MA: Complement factor H variant increases the risk of age-related macular degeneration. Science 2005;308:419-421.
10. Anderson DH, Mullins RF, Hageman GS, Johnson LV: A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol 2002;134:411-431.
11. Knisely TL, Bleicher PA, Vibbard CA, Granstein RD: Production of latent transforming growth factor-beta and other inhibitory factors by cultured murine iris and ciliary body cells. Curr Eye Res 1991;10:761-771.
12. Streilein JW, Bradley D: Analysis of immunosuppressive properties of iris and ciliary body cells and their secretory products. Invest Ophthalmol Vis Sci 1991;32:2700-2710.
13. Griffith TS, Ferguson TA: The role of FasL-induced apoptosis in immune privilege. Immunol Today 1997;18:240-244.
14. Jorgensen A, Wiencke AK, la Cour M, Kaestel CG, Madsen HO, Hamann S, Lui GM, Scherfig E, Prause JU, Svejgaard A, Odum N, Nissen MH, Ropke C: Human retinal pigment epithelial cell-induced apoptosis in activated T cells. Invest Ophthalmol Vis Sci 1998;39:1590-1599.
15. Yoshida M, Takeuchi M, Streilein JW: Participation of pigment epithelium of iris and ciliary body in ocular immune privilege. 1. Inhibition of T-cell activation in vitro by direct cell-to-cell contact. Invest Ophthalmol Vis Sci 2000;41:811-821.
16. Yoshida M, Kezuka T, Streilein JW: Participation of pigment epithelium of iris and ciliary body in ocular immune privilege. 2. Generation of TGF-beta-producing regulatory T cells. Invest Ophthalmol Vis Sci 2000;41:3862-3870.
17. Ishida K, Panjwani N, Cao Z, Streilein JW: Participation of pigment epithelium in ocular immune privilege. 3. Epithelia cultured from iris, ciliary body, and retina suppress T-cell activation by partially non-overlapping mechanisms. Ocul Immunol Inflamm 2003;11:91-105.
18. Zamiri P, Masli S, Kitaichi N, Taylor AW, Streilein JW: Thrombospondin plays a vital role in the immune privilege of the eye. Invest Ophthalmol Vis Sci 2005;46:908-919.
19. Tanihara H, Yoshida M, Matsumoto M, Yoshimura N: Identification of transforming growth factor-beta expressed in cultured human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 1993;34:413-419.
20. Obata H, Kaji Y, Yamada H, Kato M, Tsuru T, Yamashita H: Expression of transforming growth factor-beta superfamily receptors in rat eyes. Acta Ophthalmol Scand 1999;77:151-156.
21. Lawler J: The functions of thrombospondin-1 and -2. Curr Opin Cell Biol 2000;12:634-640.
22. Murphy-Ullrich JE, Poczatek M: Activation of latent TGF-beta by thrombospondin-1: Mechanisms and physiology. Cytokine Growth Factor Rev 2000;11:59-69.
23. Miyajima-Uchida H, Hayashi H, Beppu R, Kuroki M, Fukami M, Arakawa F, Tomita Y, Kuroki M, Oshima K: Production and accumulation of thrombospondin-1 in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 2000;41: 561-567.
24. Elner SG: Human retinal pigment epithelial lysis of extracellular matrix: Functional urokinase plasminogen activator receptor, collagenase, and elastase. Trans Am Ophthalmol Soc 2002;100: 273-299.
25. Patel YC: Somatostatin and its receptor family. Front Neuroendocrinol 1999;20:157-198.
26. Blum AM, Metwali A, Mathew RC, Cook G, Elliott D, Weinstock JV: Granuloma T lymphocytes in murine schistosomiasis mansoni have somatostatin receptors and respond to somatostatin with decreased IFN-gamma secretion. J Immunol 1992;149:3621-3626.
27. Klisovic DD, O'Dorisio MS, Katz SE, Sall JW, Balster D, O'Dorisio TM, Craig E, Lubow M: Somatostatin receptor gene expression in human ocular tissues: RT-PCR and immunohistochemical study. Invest Ophthalmol Vis Sci 2001;42: 2193-2201.
28. Zamiri P, Masli S, Streilein JW, Taylor AW: Pigment epithelial growth factor suppresses inflammation by modulating macrophage activation. Invest Ophthalmol Vis Sci 2006;47:3912-3918.
29. Taylor AW, Yee DG: Somatostatin is an immunosuppressive factor in aqueous humor. Invest Ophthalmol Vis Sci 2003;44:2644-2649.
30. Karakousis PC, John SK, Behling KC, Surace EM, Smith JE, Hendrickson A, Tang WX, Bennett J, Milam AH: Localization of pigment epithelium derived factor (PEDF) in developing and adult human ocular tissues. Mol Vis 2001;7:154-163.
31. Cohen J, Sugita Y, Chader GJ, Schwartz JP: Recombinant forms of the neurotrophic factor pigment epithelium-derived factor activate cellular metabolism and inhibit proliferation of the RAW macrophage cell line. Neuroimmunomodulation 2000;7:51-58.
32. Sugita S, Streilein JW: Iris pigment epithelium expressing CD86 (B7-2) directly suppresses T cell activation in vitro via binding to cytotoxic T lymphocyte-associated antigen 4. J Exp Med 2003;198: 161-171.
33. Greenwald RJ, Boussiotis VA, Lorsbach RB, Abbas AK, Sharpe AH: CTLA-4 regulates induction of anergy in vivo. Immunity 2001;14:145-155.
34. + T lymphocytes induced by CTLA-4 crosslinking. Proc Natl Acad Sci USA 1998;95:10083-10088.
35. Levings MK, Sangregorio R, Sartirana C, et al: Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells. J Exp Med 2002;196:1335-1346.
36. + regulatory cells that control intestinal inflammation. J Exp Med 2000;192:295-302.
37. + regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med 2000;192:303-310.
38. Griffith TS, Brunner T, Fletcher SM, Green DR, Ferguson TA: Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 1995;270:1189-1192.
39. LAe HO, Herndon JM, Barreiro R, Griffith TS, Ferguson TA: TRAIL: a mechanism of tumor surveillance in an immune privileged site. J Immunol 2002;169:4739-4744.
40. Wang S, Boonman ZF, Li HC, et al: Role of TRAIL and IFN-gamma in CD4+ T cell-dependent tumor rejection in the anterior chamber of the eye. J Immunol 2003;171:2789-2796.
41. Mieziewska K: The interphotoreceptor matrix, a space in sight. Microsc Res Tech 1996;35: 463-471.
42. Wenkel H, Streilein JW: Evidence that retinal pigment epithelium functions as an immune-privileged tissue. Invest Ophthalmol Vis Sci 2000;41:3467-3473.
43. Streilein JW, Ma N, Wenkel H, Ng TF, Zamiri P: Immunobiology and privilege of neuronal retina and pigment epithelium transplants. Vision Res 2002;42:487-495.
44. Kaplan HJ, Tezel TH, Berger AS, Del Priore LV: Retinal transplantation; in Streilein JW (ed): Immune Response and the Eye. Chem Immunol. Basel, Karger, 1999, vol 73, pp 207-219.
45. Ashton N: Bowman lecture. The blood-retinal barrier and vaso-glial relationships in retinal disease. Trans Ophthalmol Soc UK 1965;85:199-230.
46. Marmor MF: Mechanisms of fluid accumulation in retinal edema. Doc Ophthalmol 1999;97: 239-249.
47. Caspi RR, Roberge FG: GlialCcells as suppressor cells: characterization of the inhibitory function. J Autoimmun 1989;2:709-722.
48. Liversidge J, McKay D, Mullen G, Forrester JV: Retinal pigment epithelial cells modulate lymphocyte function at the blood-retina barrier by autocrine PGE2 and membrane-bound mechanisms. Cell Immunol 1993;149:315-330.