Immune privilege is extended, then withdrawn, from allogeneic tumor cell grafts placed in the subretinal space

Investigative Ophthalmology and Visual Science

Volumn 40, Issue 13, 1999, Pages 3202-3208

  Wenkel, Hartmut ^a   Chen, Peter W ^a   Ksander, Bruce R ^a   Streilein, J Wayne ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR EYE CHAMBER; ARTICLE; CANCER TRANSPLANTATION; CONJUNCTIVA; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; FEMALE; IMMUNOLOGICAL TOLERANCE; IMMUNOREACTIVITY; IMMUNOREGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETINA;

ANIMALS; ANTERIOR CHAMBER; CELL SURVIVAL; EYE NEOPLASMS; FEMALE; HYPERSENSITIVITY, DELAYED; IMMUNITY; IMMUNIZATION; MAST-CELL SARCOMA; MICE; MICE, INBRED BALB C; MICE, INBRED DBA; MICE, SCID; NEOPLASM TRANSPLANTATION; OVALBUMIN; RETINA; TRANSPLANTATION, HOMOLOGOUS;

EID: 0032698011     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Streilein JW. Immune regulation and the eye: a dangerous compromise. FASEB J. 1987;1:199-208.
2. Streilein JW, Niederkorn JY, Shadduck JA. Systemic immune unresponsiveness induced in adult mice by anterior chamber presentation of minor histocompatibility antigens. J Exp Med. 1980;152: 1121-1125.
3. Streilein JW, Niederkorn JY. Characterization of the suppressor cell(s) responsible for anterior chamber-associated immune deviation (ACAID) induced in BALB/c mice by P815 cells. J Immunol. 1985;134:1381-1387.
4. Mizuno K, Clark AF, Streilein JW. Anterior chamber-associated immune deviation induced by soluble antigens. Invest Ophthalmol Vis Sci. 1989;30:1112-1119.
5. Wilbanks GA, Streilein JW. Characterization of suppressor cells in anterior chamber-associated immune deviation (ACAID) induced by soluble antigen: evidence of two functionally and phenotypically distinct T-suppressor cell populations. Immunology. 1990; 71:383-389.
6. Niederkorn J, Streilein JW, Shadduck JA. Deviant immune responses to allogeneic tumors injected intracamerally and subcutaneously in mice. Invest Ophthalmol Vis Sci. 1980;20:355-363.
7. Niederkorn JY, Streilein JW. Lymphoma allografts abrogate immune privilege within the anterior chamber of the eye. Invest Ophthalmol Vis Sci. 1986;27:1235-1243.
8. Ksander B, Streilein JW. Immune privilege to MHC-disparate tumor grafts in the anterior chamber of the eye. Transplantation. 1989; 47:661-667.
9. Jiang LQ, Streilein JW. Immune privilege extended to allogeneic tumor cells in the vitreous cavity. Invest Ophthalmol Vis Sci. 1991;32:224-228.
10. Gregerson DS. Immune privilege in the retina. Ocul Immunol Inflamm. 1998;6:257-267.
11. Jiang LQ, Jorquera M, Streilein JW. Subretinal space and vitreous cavity as immunologically privileged sites for retinal allografts. Invest Ophthalmol Vis Sci. 1993;34:3347-3354.
12. Wenkel H, Streilein JW. Analysis of immune deviation elicited by antigens injected into the subretinal space. Invest Ophthalmol Vis Sci. 1998;39:1823-1834.
13. Jiang LQ, Jorquera M, Streilein JW. Immunologic consequences of intraocular implantation of retinal pigment epithelial allografts Exp Eye Res. 1994;58:719-728.
14. Chen PW, Geer DC, Podack ER, Ksander BR. Tumor cells transfected with B7.1 and interleukin-12 cDNA induce protective immunity. Ann N Y Acad Sci. 1996;795:325-327.
15. Niederkorn JY, Streilein JW. Intracamerally induced concomitant immunity: mice harboring progressively growing intraocular tumors are immune to spontaneous metastasis and secondary tumor challenge. J Immunol. 1983;131:2587-2594.
16. Niederkorn JY, Streilein JW. Deviant immune response to allogeneic tumor cells placed into the anterior chamber protect the intraocular neoplasm, but prevent metastasis. Transplant Proc. 1983;15:401-403.
17. Streilein JW, Ksander BR, Taylor AW. Immune deviation in relation to ocular immune privilege. J Immunol. 1997;158:3557-3560.
18. Niderkorn JY, Streilein JW. Adoptive transfer of immunity to intraocular tumors in mice. Invest Ophthalmol Vis Sci. 1984;25: 336-342.
19. Ksander BR, Uno T, Chen PW. Establishing immune privilege at non-privileged extra-ocular sites [ARVO Abstract]. Invest Ophthalmol Vis Sci. 1998;39(4):S910. Abstract nr 4190.
20. Jiang LQ, Jorquera M, Streilein JW, Ishioka M. Unconventional rejection of neural retinal allografts implanted into the immunologically privileged site of the eye. Transplantation. 1995;59: 1201-1207.