Oxidative stress-induced C-jun N-terminal kinase (JNK) activation in tendon cells upregulates MMP1 mRNA and protein expression

Journal of Orthopaedic Research

Volumn 25, Issue 3, 2007, Pages 378-389

  Wang, Fang ^a   Murrell, George A C ^a   Wang, Min Xia ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

c Jun N terminal kinase (JNK); Hydrogen peroxide; Matrix metalloproteinase1 (MMP1); Oxidative stress; Rotator cuff tear; Supraspinatus tendon

Indexed keywords

HYDROGEN PEROXIDE; INTERSTITIAL COLLAGENASE; MESSENGER RNA; STRESS ACTIVATED PROTEIN KINASE;

ADULT; ARTICLE; CONNECTIVE TISSUE CELL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; ROTATOR CUFF RUPTURE; TENDON DISEASE; TISSUE DEGENERATION; UPREGULATION; WESTERN BLOTTING;

HUMANS; HYDROGEN PEROXIDE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MATRIX METALLOPROTEINASE 1; OXIDATIVE STRESS; RNA, MESSENGER; TENDONS; UP-REGULATION;

EID: 33947368716     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20294     Document Type: Article

References (46)

1. Rekola KE, Keinanen-Kiukaanniemi S, Takala J. 1993. Use of primary health services in sparsely populated country districts by patients with musculoskeletal symptoms: consultations with a physician. J Epidemiol Community Health 47:153-157.
2. Fukuda H. 2003. The management of partial-thickness tears of the rotator cuff. J Bone Joint Surg Br 85:3-11.
3. Birch HL, Wilson AM, Goodship AE. 1997. The effect of exercise-induced localised hyperthermia on tendon cell survival. J Exp Biol 200(Pt 11):1703-1708.
4. Skutek M, van Griensven M, Zeichen J, et al. 2003. Cyclic mechanical stretching of human patellar tendon fibroblasts: activation of JNK and modulation of apoptosis. Knee Surg Sports Traumatol Arthrosc 11:122-129.
5. Lehman C, Cuomo F, Kummer FJ, et al. 1995. The incidence of full thickness rotator cuff tears in a large cadaveric population. Bull Hosp Jt Dis 54:30-31.
6. Sher JS, Uribe JW, Posada A, et al. 1995. Abnormal findings on magnetic resonance images of asymptomatic shoulders. J Bone Joint Surg Am 77:10-15.
7. Ashok BT, Ali R. 1999. The aging paradox: free radical theory of aging. Exp Gerontol 34:293-303.
8. Droge W. 2003. Oxidative stress and aging. Adv Exp Med Biol 543:191-200.
9. Nelson KK, Melendez, JA. 2004. Mitochondrial redox control of matrix metalloproteinases. Free Radic Biol Med 37:768-784.
10. Wallace DC. 2001. A mitochondrial paradigm for degenerative diseases and ageing. Novartis Found Symp 235:247-263; discussion 263-266.
11. Yuan J, Murrell GA, Wei AQ, et al. 2002. Apoptosis in rotator cuff tendonopathy. J Orthop Res 20:1372-1379.
12. Yuan J, Murrell GA, Trickett A, et al. 2003. Involvement of cytochrome c release and caspase-3 activation in the oxidative stress-induced apoptosis in human tendon fibroblasts. Biochim Biophys Acta 1641:35-41.
13. Yuan J, Murrell GA, Trickett A, et al. 2004. Overexpression of antioxidant enzyme peroxiredoxin 5 protects human tendon cells against apoptosis and loss of cellular function during oxidative stress. Biochim Biophys Acta 1693:37-45.
14. Kjaer M. 2004. Role of extracellular matrix in adaptation of tendon and skeletal muscle to mechanical loading. Physiol Rev 84:649-698.
15. Gotoh M, Hamada K, Yamakawa H, et al. 1997. Significance of granulation tissue in torn supraspinatus insertions: an immunohistochemical study with antibodies against interleukin-1 beta, cathepsin D, and matrix metalloprotease-1. J Orthop Res 15:33-39.
16. Gross J, Harper E, Harris ED, et al. 1974. Animal collagenases: specificity of action, and structures of the substrate cleavage site. Biochem Biophys Res Commun 61:605-612.
17. Gomez DE, Alonso DF, Yoshiji H, et al. 1997. Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Eur J Cell Biol 74:111-122.
18. Corps AN, Curry VA, Buttle DJ, et al. 2004. Inhibition of interleukin-1beta-stimulated collagenase and stromelysin expression in human tendon fibroblasts by epigallocatechin gallate ester. Matrix Biol 23:163-169.
19. Westermarck J, Holmstrom T, Ahonen M, et al. 1998. Enhancement of fibroblast collagenase-1 (MMP-1) gene expression by tumor promoter okadaic acid is mediated by stress-activated protein kinases Jun N-terminal kinase and p38. Matrix Biol 17:547-557.
20. Filomeni G, Aquilano K, Rotilio G, et al. 2003. Reactive oxygen species-dependent c-Jun NH2-terminal kinase/c-Jun signaling cascade mediates neuroblastoma cell death induced by diallyl disulfide. Cancer Res 63:5940-5949.
21. Lei K, Davis RJ. 2003. JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc Natl Acad Sci USA 100:2432-2437.
22. Gupta S, Barrett T, Whitmarsh AJ, et al. 1996. Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO J 15:2760-27670.
23. Arnoczky SP, Tian T, Lavagnino M, et al. 2002. Activation of stress-activated protein kinases (SAPK) in tendon cells following cyclic strain: the effects of strain frequency, strain magnitude, and cytosolic calcium. J Orthop Res 20:947-952.
24. Ireland D, Harrall R, Curry V, et al. 2001. Multiple changes in gene expression in chronic human Achilles tendinopathy. Matrix Biol 20:159-169.
25. Howe JG, Crouch J, Cooper D, et al. 2004. Real-time quantitative reverse transcription-PCR for cyclin D1 mRNA in blood, marrow, and tissue specimens for diagnosis of mantle cell lymphoma. Clin Chem 50:80-87.
26. Nystrom K, Biller M, Grahn A, et al. 2004. Real time PCR for monitoring regulation of host gene expression in herpes simplex virus type 1-infected human diploid cells. J Virol Methods 118:83-94.
27. Power C, Henry S, Del Bigio MR, et al. 2003. Intracerebral hemorrhage induces macrophage activation and matrix metalloproteinases. Ann Neurol 53:731-742.
28. Fu SC, Chan BP, Wang W, et al. 2002. Increased expression of matrix metalloproteinase 1 (MMP1) in 11 patients with patellar tendinosis. Acta Orthop Scand 73:658-662.
29. Nagase H, Woessner JF Jr. 1999. Matrix metalloproteinases. J Biol Chem 274:21491-21494.
30. Seiki M. 2003. Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion. Cancer Lett 194: 1-11.
31. Arany I, Megyesi JK, Kaneto H, et al. 2004. Activation of ERK or inhibition of JNK ameliorates H(2)O(2) cytotoxicity in mouse renal proximal tubule cells. Kidney Int 65:1231-1239.
32. Marques CA, Keil U, Bonert A, et al. 2003. Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway. J Biol Chem 278: 28294-28302.
33. Manning AM, Davis RJ. 2003. Targeting JNK for therapeutic benefit: from junk to gold? Nat Rev Drug Discov 2:554-565.
34. Yang DD, Kuan CY, Whitmarsh AJ, et al. 1997. Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature 389:865-870.
35. Han Z, Boyle DL, Chang L, et al. 2001. c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. J Clin Invest 108:73-81.
36. Han Z, Chang L, Yamanishi Y, et al. 2002. Joint damage and inflammation in c-Jun N-terminal kinase 2 knockout mice with passive murine collagen-induced arthritis. Arthritis Rheum 46:818-823.
37. Li Y, Arita Y, Koo HC, et al. 2003. Inhibition of c-Jun N-terminal kinase pathway improves cell viability in response to oxidant injury. Am J Respir Cell Mol Biol 29:779-783.
38. Tang F, Tang G, Xiang J, et al. 2002. The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis. Mol Cell Biol 22:8571-8579.
39. Chang L, Karin M. 2001. Mammalian MAP kinase signalling cascades. Nature 410:37-40.
40. Lin A. 2003. Activation of the JNK signaling pathway: breaking the brake on apoptosis. Bioessays 25: 17-24.
41. Bennett BL, Sasaki DT, Murray BW, et al. 2001. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci USA 98:13681-13686.
42. Oh SM, Hahm DH, Kim IH, et al. 2001. Human neutrophil lactoferrin trans-activates the matrix metalloproteinase 1 gene through stress-activated MAPK signaling modules. J Biol Chem 276:42575-42579.
43. Riley GP, Harrall RL, Cawston TE, et al. 1996. Tenascin-C and human tendon degeneration. Am J Pathol 149:933-943.
44. Riley GP, Harrall RL, Constant CR, et al. 1994. Tendon degeneration and chronic shoulder pain: changes in the collagen composition of the human rotator cuff tendons in rotator cuff tendinitis. Ann Rheum Dis 53:359-366.
45. Bogoyevitch MA, Boehm I, Oakley A, et al. 2004. Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential. Biochim Biophys Acta 1697:89-101.
46. Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2[-ΔΔC(T)] method. Methods 25:402-408.