Enhancement of fibroblast collagenase-1 (MMP-1) gene expression by tumor promoter okadaic acid is mediated by stress-activated protein kinases Jun N-terminal kinase and p38

Matrix Biology

Volumn 17, Issue 8-9, 1998, Pages 547-557

  Westermarck, Jukka ^a,b   Holmström, Tim ^c   Ahonen, Matti ^a,b   Eriksson, John E ^c   Kähäri, Veli Matti ^a,b  

^a UNIVERSITY OF TURKU   (Finland)

^b TURKU UNIVERSITY HOSPITAL   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

Author keywords

MAP kinase; Matrix metalloproteinase; Okadaic acid; PP2A

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; COLLAGENASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; TUMOR PROMOTER;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROBLAST; GENE ACTIVATION; HUMAN; HUMAN CELL; MALE; NORMAL HUMAN; PRIORITY JOURNAL;

EID: 0032432798     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(98)90107-X     Document Type: Article

References (53)

1. Alessi, D.R., Cuenda, A., Cohen, P., Dudley, D.T. and Saltiel, A.R.: PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270: 27489-27494, 1995.
2. Alessi, D.R., Smythe, C. and Keyse, S.M.: The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts. Oncogene 8: 2015-2020, 1993.
3. Bolon, I., Gouyer, V., Devouassoux, M., Vandenbunder, B., Wernert, N., Moro, D., Brambilla, C. and Brambilla, E.: Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas. Am. J. Pathol. 147: 1298-1310, 1995.
4. Cano, E., Hazzalin, C.A. and Mahadevan, L.C.: Anisomycin-activated protein kinases p45 and p55 but not mitogen-activated protein kinases ERK-1 and -2 are implicated in the induction of c-fos and c-jun. Mol. Cell. Biol. 14: 7352-7362, 1994.
5. Casillas, A.M., Amaral, K., Chegini Farahani, S. and Nel, A.E.: Okadaic acid activates p42 mitogen-activated protein kinase (MAP kinase; ERK-2) in B-lymphocytes but inhibits rather than augments cellular proliferation: contrast with phorbol 12-myristate 13-acetate. Biochem. J. 290; 545-550, 1993.
6. Chomczynski, P. and Sacchi, N.: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162; 156-159, 1987.
7. Chu, Y., Solski, P.A., Khosravi Far, R., Der, C.J. and Kelly, K.: The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation. J. Biol. Chem. 271: 6497-6501, 1996.
8. Clerk, A. and Sudgen P.H.: The p38-MAPK inhibitor, SB203580 inhibits cardiac stress-activated protein kinases/c-Jun N-terminal kinascs (SAPK/JNKs). FEBS Lett. 426: 93-96, 1998.
9. Cowley, S., Paterson, H., Kemp, P. and Marshall, C.J.: Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77: 841-852, 1994.
10. Cuenda, A., Rouse, J., Doza, Y.N., Meier, R., Cohen, P., Gallagher, T.F., Young, P.R. and Lee, J.C.: SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett. 264: 229-233, 1995.
11. Dudley, D.T., Pang, L. Decker, S.T., Bridges, A.J. and Saltiel, A.R.: A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA 92; 7686-7689, 1995.
12. Favre, B., Turowski, P. and Hemmings, B.A.: Differential inhibition and posttranslational modification of protein phosphatasc 1 and 2A in MCF7 cells treated with calyculin-A, okadaic acid, and tautomycm. J. Biol. Chem. 272: 13856-13863, 1997.
13. Fort, P., Marty, L., Piechaczyk, M., El Sabrouty, S., Dani, C., Jeanteur, P. and Blanchard, J.M.: Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family. Nucleic Acids Res. 13: 1431-1441, 1985.
14. Frisch, S.M., Reich, R., Collier, I.E., Genrich, L.T., Martin, G. and Goldberg, G.I.: Adenovirus E1A represses protease gene expression and inhibits metastasis of human tumor cells. Oncogene 5:75-83, 1990.
15. Frost, J.A., Geppert, T.D., Cobb, M.H. and Feramisco, J.R.: A requirement for extracellular signal-regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum. Proc. Natl. Acad. Sci. USA 91: 3844-3848, 1994.
16. Goldberg, G.I., Wilhelm, S.M., Kronberger, A., Bauer, E.A., Grant, G.A. and Eisen, A.Z.: Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein. J. Biol. Chem. 261: 6600-6605, 1986.
17. Gomez, N. and Cohen, P.: Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases. Nature 353: 170-173, 1991.
18. Gray, S.T., Wilkins, R.J. and Yun, K.: Interstitial collagenase gene expression in oral squamous cell carcinoma. Am. J. Pathol. 141: 301-306, 1992.
19. Gray, S.T., Yun, K., Motoori, T. and Kuys, Y.M.: Interstitial collagenase gene expression in colonic neoplasia. Am. J. Pathol. 143: 663-671, 1993.
20. Gum, R., Lengyel, E., Juarez, J., Chen, J.H., Sato, H., Seiki, M. and Boyd, D.: Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences. J. Biol. Chem. 271: 10672-30680, 1996.
21. Gum, R.J., McLaughlin, M.M., Kumar, S., Wang, Z., Bower, M.J., Lee, J.C., Adams, J.L., Livi, G.P., Goldsmith, K.J. and Young, P.R.: Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket. J. Biol. Chem. 273: 15605-15610, 1998.
22. Gum, R., Wang, H., Lengyel, E., Juarez, J. and Boyd, D.: Regulation of 92 kDa type IV collagenase expression of the jun aminoterminal kinase- and the extracellular signal-regulated kinase-dependent signaling cascades. Oncogen 14: 1481-1493, 1997.
23. Hunter, T.: Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell 80: 225-236, 1995.
24. Johansson, N., Airola, K., Grénman, R., Kariniemi, A.-L., Saarialho-Kere, U. and Kähäri, V.-M.: Expression of collagenase-3 (matrix metalloproteinase-13) in squamous cell carcinomas of the head and neck. Am. J. Pathol. 151: 499-508, 1997.
25. Kähäri, V.-M. and Saarialho-Kere, U.: Matrix metalloproteinases in skin. Exp. Dermatol. 6: 199-213, 1997.
26. Kim, S.J., Lafyatis, R., Kim, K.Y., Angel, P., Fujiki, H., Karin, M., Sporn, M.B. and Roberts, A.R.: Regulation of collagenase gene expression by okadaic acid, an inhibitor of protein phosphatases. Cell. Regul. 1: 269-278, 1990.
27. Klemke, R., Cai, S., Giannini, A., Gallagner, P., de Lanerolle, P. and Cheresh, D.: Regulation of cell motility by mitogen-activated protein kinase. J. Cell Biol. 137: 481-492, 1997.
28. Korzus, E., Nagase, H., Rydell, R. and Travis, J.: The mitogen-activated protein kinase and JAK-STAT signaling pathways are required for an oncostatin M-responsive element-mediated activation of matrix metalloproteinase 1 gene expression. J. Biol. Chem. 272: 1188-1196, 1997.
29. Kumar, S., McDonnell, P.C., Gum, R.J., Hand, A.T., Lee, J.C. and Young, P.R.: Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles. Biochem. Biophys. Res. Commun. 235: 533-538, 1997.
30. Kyriakis, J.M., Banerjee, P., Nikolakaki, E., Dai, T., Rubie, E.A., Ahmad, M.F., Avruch, J. and Woodgett, J.R.: The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369: 156-160, 1994.
31. Lin, A., Minden, A., Martinetto, H., Claret, F.-X., Lange-Carter, C., Mercurio, F., Johnson, G.L. and Karin, M.: Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2. Science 268: 286-290, 1995.
32. Ludwig, S., Engel, K., Hoffmeyer, A., Sithanandam, G., Neufeld, B., Palm, D., Gaestel, M. and Rapp, U.R.: 3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways. Mol. Cell. Biol. 16: 6687-6697, 1996.
33. Mansour, S.J., Matten, W.T., Hermann, A.S., Candia, J.M., Rong, S., Fukasawa, K., Van de Woude, G.F. and Ahn, N.G.: Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265: 966-970, 1994.
34. 2 J. Biol. Chem. 271: 26981-26988, 1996.
35. Murray, G.I., Duncan, M.E., O'Neil, P., Melvin, W.T. and Fothergill, J.E.: Matrix metalloproteinase-1 is associated with poor prognosis in colorectal cancer. Nat. Med. 2: 461-462, 1996.
36. Oka, H., Chatani, Y., Hoshino, R., Ogawa, O., Kakehi, Y., Terachi, T., Okada, Y., Kawaichi, M., Kohno, M. and Yoshida, O.: Constitutive activation of mitogen-activated protein (MAP) kinases in human renal cell carcinoma. Cancer Res. 55: 4182-4187, 1995.
37. Price, M.A., Cruzalegui, F.H. and Treisman, R.: The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c-fos transcription in response to UV light. EMBO J. 15: 6552-6563, 1996.
38. Raingeaud, J., Gupta, S., Rogers, J.S., Dickens, M., Han, J., Ulevitch, R.J. and Davis, R.J.: Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270: 7420-7426, 1995.
39. Reunanen, N., Westermarck, J., Häkkinen, L., Holmström, T., Elo, I., Eriksson, J. and Kähäri, V.-M.: Enhancement of fibroblast collagenase (matrix metalloproteinase-1) gene expression by ceramide is mediated by extracellular signal-regulated and stress-activated protein kinase pathways. J. Biol. Chem. 273: 5137-5145, 1998.
40. Ridley, S.H., Sarsfield, S.J., Lee, J.C., Bigg, H.F., Cawston, T.E., Taylor, D.J., DeWitt, D.L. and Saklatvala, J.: Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase: regulation of prostaglandin H synthase-2, metalloprotcinases, and IL-6 at different levels. J. Immunol. 158: 3165-3173, 1997.
41. Rincon, M., Enslen, H., Raingeaud, J., Recht, M., Zapton, T, Su, M.S., Penix, L.A., Davis, R.J. and Flavell, R.A.: Interferon-γ expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway. EMBO J. 17: 2817-2829, 1998.
42. Robinson, M.J. and Cobb, M.H.: Mitogen-activated protein kinase pathways. Curr. Opin, Cell Biol. 9: 180-186, 1997.
43. Salmeron, A., Ahmad, T.B., Carlile, G.W., Pappin, D., Narsimhan, R.P. and Ley, S.C.: Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase. EMBO J. 15: 817-826, 1996.
44. Sanchez, I., Hughes, R.T., Mayer, B.J., Yee, K., Woodgett, J.R., Avruch, J Kyriakis, J.M. and Zon, L.I.: Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature 372: 794-798, 1994.
45. Simon, C., Goepfert, H. and Boyd, D.: Inhibition of the p38 mitogen-activated protein kinase by SB 203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion. Cancer Res. 58: 1135-1139, 1998.
46. Sivaraman, V., Wang, H., Nuovo, G. and Malbon, C.: Hyperexpression of mitogen-activated protein kinase in human breast cancer. J. Clin. Invest. 99: 1478-1483, 1997.
47. Tournier, C., Whitmarsh, A.J., Cavanagh, J., Barrett, T. and Davis, R.J.: Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase. Proc. Natl. Acad. Sci. USA 94: 7337-7342, 1997.
48. Treisman, R.: Regulation of transcription by MAP kinase cascades. Curr. Opin. Cell Biol. 8: 205-215, 1996.
49. Urbanski, S.J., Edwards, D.R., Maitland, A., Leco, K.J., Watson, A. and Kossakowska, A.E.: Expression of metalloproteinases and their inhibitors in primary pulmonary carcinomas. Br. J. Cancer 66: 1188-1194, 1992.
50. Westermarck, J., Lohi, J., Keski Oja, J. and Kähäri, V.-M.: Okadaic acid-elicited transcriptional activation of collagenase gene expression in HT-1080 fibrosarcoma cells is mediated by JunB. Cell Growth Differ. 5: 1205-1213, 1994.
51. Westermarck, J., Seth, A. and Kähäri, V.-M.: Differential regulation of interstitial collagenase (MMP-1) gene expression by ETS transcription factors. Oncogene 14: 2651-2660, 1997.
52. Whitmarsh, A.J., Shore, P., Sharrocks, A.D. and Davis, R.J.: Integration of MAP kinase signal transduction pathways at the serum response element. Science 269: 403-407, 1995.
53. Whitmarsh, A.J., Yang, S.-H., Su, M.S., Sharrocks, A.D. and Davis, R.J.: Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors. Mol. Cell. Biol. 17: 2360-2371.