Chemical Genetic Screening Identifies Critical Pathways in Anthrax Lethal Toxin-Induced Pathogenesis

Chemistry and Biology

Volumn 14, Issue 3, 2007, Pages 245-255

  Panchal, Rekha G ^a   Ruthel, Gordon ^b   Brittingham, Katherine C ^b   Lane, Douglas ^a   Kenny, Tara A ^a   Gussio, Rick ^c   Lazo, John S ^d   Bavari, Sina ^b  

^a SAIC FREDERICK INC   (United States)

^b UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^c Developmental Therapeutics Program   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

CHEMBIOL; MOLIMMUNO; SIGNALING

Indexed keywords

ANTHRAX TOXIN; BACTERIAL ANTIGEN; BACTERIAL TOXIN; CDC25B PHOSPHATASE; CELL CYCLE PROTEIN; CYTOKINE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL; APOPTOSIS; ARTICLE; CELL DEATH; CELL LINE; CONFOCAL MICROSCOPY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETIC SCREENING; MACROPHAGE; METABOLISM; METHODOLOGY; MOUSE; NECROSIS; PHYSIOLOGY;

ANIMALS; ANTIGENS, BACTERIAL; APOPTOSIS; BACTERIAL TOXINS; CDC25 PHOSPHATASE; CELL CYCLE PROTEINS; CELL DEATH; CELL LINE; CYTOKINES; GENETIC SCREENING; MACROPHAGES; MICE; MICROSCOPY, CONFOCAL; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NECROSIS;

EID: 33947247554     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2007.01.007     Document Type: Article

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