Calyculin A sensitive protein phosphatase is required for Bacillus anthracis lethal toxin induced cytotoxicity

Current Microbiology

Volumn 44, Issue 2, 2002, Pages 106-111

  Kau, Jyh Hwa ^a   Lin, Ching Gong ^b   Huang, Hsin Hsien ^a   Hsu, Hui Ling ^a   Chen, Kuo Ching ^a   Wu, Yu Ping ^a   Lin, Hung Chi ^a  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; CALYCULIN A; CYCLOSPORIN A; GENISTEIN; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PROTEIN KINASE INHIBITOR; SPHINGOSINE; TAUTOMYCIN; TOXIN;

ANIMAL CELL; ARTICLE; BACILLUS ANTHRACIS; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL;

ANIMALS; ANTIBIOTICS, ANTIFUNGAL; ANTIGENS, BACTERIAL; BACILLUS ANTHRACIS; BACTERIAL TOXINS; BLOTTING, WESTERN; CELLS, CULTURED; CYCLOSPORINE; ENZYME INHIBITORS; GENISTEIN; MAP KINASE KINASE KINASE 1; MICE; OKADAIC ACID; OXAZOLES; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN-SERINE-THREONINE KINASES; PYRANS; SIGNAL TRANSDUCTION; SPHINGOSINE; SPIRO COMPOUNDS;

ANIMALIA; ANTHRAX; BACILLUS ANTHRACIS;

EID: 0036140948     PISSN: 03438651     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00284-001-0059-8     Document Type: Article

References (16)

1. The role of phosphatases in signal transduction
2. Protein synthesis is required for expression of anthrax lethal toxin cytotoxicity
3. Calcium is required for the expression of anthrax lethal toxin activity in the macrophage-like cell line J774A.1
4. Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor
5. Anthrax protective antigen interacts with a specific receptor on the surface of CHO-K1 cells
6. Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process
7. Characterization of macrophage sensitivity and resistance to anthrax lethal toxin
8. Biochemical and physiological changes induced by anthrax lethal toxin in J774A.1 macrophage-like cells
9. Calyculin A and Okadaic acid: Inhibitors of protein phosphatase activity
10. Phosphorylation of the core protein of hepatitis B virus by a 46-kDa serine kinase
11. Production and purification of anthrax toxin
12. Anthrax toxin
13. Cytotoxic effects of Bacillus anthracis lethal toxin on macrophagelike cell line J774A.1
14. Role of phosphorylation in regulation of the assembly of endocytic coat complexes
15. Anthrax lethal factor cleaves the N-termnus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages
16. Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3