Transition-state analysis of S. pneumoniae 5′-methylthioadenosine nucleosidase

Journal of the American Chemical Society

Volumn 129, Issue 10, 2007, Pages 2783-2795

  Singh, Vipender ^a   Schramm, Vern L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMMITMENT FACTOR; HYPERCONJUGATION; KINETIC ISOTOPE EFFECTS (KIE); RIBOOXACARBENIUM ION; RIBOSYL HYDROXYLS; TRANSITION STATE ANALYSIS;

CATALYSIS; CRYSTAL ORIENTATION; ESCHERICHIA COLI; ISOTOPES; POLARIZATION; TORSION TESTING; VAN DER WAALS FORCES;

ENZYME KINETICS;

5' METHYLTHIOADENOSINE; ADENINE; HYDROXYL GROUP; ISOTOPE; METHYL GROUP; METHYLTHIOADENOSINE NUCLEOSIDASE; NUCLEOSIDASE; RIBOSE; S ADENOSYLHOMOCYSTEINE; SOLVENT; SULFUR; TRANSFERASE; UNCLASSIFIED DRUG; WATER;

AB INITIO CALCULATION; ARTICLE; BIOTRANSFORMATION; COMPUTER MODEL; CONFORMATION; CONJUGATION; COVALENT BOND; DENSITY FUNCTIONAL THEORY; DIELECTRIC CONSTANT; DIPOLE; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME MECHANISM; ESCHERICHIA COLI; MOLECULAR INTERACTION; MOLECULAR STABILITY; NONHUMAN; POLARIZATION; PROTON TRANSPORT; STREPTOCOCCUS PNEUMONIA;

CATALYSIS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; KINETICS; MODELS, MOLECULAR; N-GLYCOSYL HYDROLASES; STREPTOCOCCUS PNEUMONIAE;

EID: 33947201538     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja065082r     Document Type: Article

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