Searching for alleles associated with complicated outcomes after burn injury

Journal of Burn Care and Research

Volumn 28, Issue 2, 2007, Pages 205-211

  Barber, Robert C ^a   Diaz Arrastia, Ramon ^a   Purdue, Gary F ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; BURN INFECTION; BURN PATIENT; BURN UNIT; DISEASE SEVERITY; EPISTASIS; GENE INTERACTION; GENE LOCUS; GENETIC PREDISPOSITION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; INFECTION RATE; INFECTION RISK; RISK ASSESSMENT;

ALLELES; BURNS; DATA INTERPRETATION, STATISTICAL; EPISTASIS, GENETIC; GENETIC PREDISPOSITION TO DISEASE; GENETICS, POPULATION; HUMANS; MODELS, GENETIC; SEPSIS; VARIATION (GENETICS);

EID: 33947182354     PISSN: 1559047X     EISSN: 15590488     Source Type: Journal    
DOI: 10.1097/BCR.0B013E318031A1BF     Document Type: Article

References (53)

1. Anlatici R, Ozerdem OR, Dalay C, et al. A retrospective analysis of 1083 Turkish patients with serious burns - Part 2: burn care, survival and mortality. Burns 2002;28:239-43.
2. Fitzwater J, Purdue GF, Hunt JL, et al. The risk factors and time course of sepsis and organ dysfunction after burn trauma. J Trauma 2003;54:959-66.
3. Angus DC, Wax RS. Epidemiology of sepsis: an update. Crit Care Med 2001;29:S109-16.
4. Bone RC. Toward an epidemiology and natural history of SIRS (systemic inflammatory response syndrome). JAMA 1992;268:3452-5.
5. Friedman G, Silva E, Vincent JL. Has the mortality of septic shock changed with time. Crit Care Med 1998;26:2078-86.
6. O'Keefe GE, Hunt JL, Purdue GF. An evaluation of risk factors for mortality after burn trauma and the identification of gender-dependent differences in outcomes. J Am Coll Surg 2001;192:153-60.
7. Abraham E, Matthay MA, Dinarello CA, et al. Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation. Crit Care Med 2000;28:232-5.
8. Sorensen TI, Nielsen GG, Andersen PK, et al. Genetic and environmental influences on premature death in adult adoptees. N Engl J Med 1988;318:727-32.
9. Agnese DM, Calvano JE, Hahm SJ, et al. Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections. J Infect Dis 2002;186:1522-5.
10. Barber RC, Aragaki CC, Rivera-Chavez FA, et al. TLR4 and TNF-alpha polymorphisms are associated with an increased risk for severe sepsis following burn injury. J Med Genet 2004;41:808-13.
11. Arnalich F, Lopez-Maderuelo D, Codoceo R, et al. Interleukin-1 receptor antagonist gene polymorphism and mortality in patients with severe sepsis. Clin Exp Immunol 2002;127:331-6.
12. O'Keefe GE, Hybki DL, Munford RS. The G->A Single Nucleotide Polymorphism at the -308 Position in the Tumor Necrosis Factor-alpha Promoter Increases the Risk for Severe Sepsis after Trauma. J Trauma 2002;52:817-26.
13. Lander E, Kruglyak L. Genetic dissection of complex traits - guidelines for interpreting and reporting linkage results. Nat Genet 1995;11:241-7.
14. Lander ES. The new genomics: Global views of biology. Science 1996;274:536-9.
15. Emahazion T, Jobs M, Howell WM, et al. Identification of 167 polymorphisms in 88 genes from candidate neurodegeneration pathways. Gene 1999;238:315-24.
16. Colhoun HM, McKeigue PM, Smith GD. Problems of reporting genetic associations with complex outcomes. Lancet 2003;361:865-72.
17. Ioannidis JPA, Trikalinos TA, Ntzani EE, et al. Genetic associations in large versus small studies: an empirical assessment. Lancet 2003;361:567-71.
18. Abecasis GR, Cherny SS, Cardon LR. The impact of genotyping error on family-based analysis of quantitative traits. Eur J Human Genet 2001;9:130-4.
19. Kirk KM, Cardon LR. The impact of genotyping error on haplotype reconstruction and frequency estimation. Eur J Human Genet 2002;10:616-22.
20. Plomin R, McClearn GE, Smith DL, et al. Dna Markers Associated with High Versus Low Iq - the Iq Quantitative Trait Loci (Qtl) Project. Behav Genet 1994;24:107-18.
21. Montana G, Pritchard JK. Statistical tests for admixture mapping with case-control and cases-only data. Am J Human Genet 2004;75:771-89.
22. Bacanu SA, Devlin B, Roeder K. Association studies for quantitative traits in structured populations. Genet Epidemiol 2002;22:78-93.
23. Bacanu SA, Devlin B, Roeder K. The power of genomic control. Am J Human Genet 2000;66:1933-44.
24. Devlin B, Bacanu SA, Roeder K. Genomic control to the extreme. Nat Genet 2004;36:1129-30.
25. Devlin B, Roeder K, Wasserman L. Genomic control, a new approach to genetic-based association studies. Theoret Pop Biol 2001;60:155-66.
26. Devlin B, Bacanu S, Wasserman L, et al. Association studies using genomic control. Am J Med Genet 2000;96:457.
27. Devlin B, Roeder K. Genomic control for association studies. Am J Human Genet 1999;65:A83.
28. Barber R, Chang L, Purdue G, et al. Detecting genetic predisposition for complicated clinical outcomes after burn injury. Burns 2006;32:821-7.
29. Pritchard JK, Donnelly P. Case-control studies of association in structured or admixed populations. Theoret Pop Biol 2001;60:227-37.
30. Pritchard JK, Stephens M, Donnelly PJ. Correcting for population stratification in linkage disequilibrium mapping studies. Am J Human Genet 1999;65:A101.
31. Pritchard JK, Rosenberg NA. Use of unlinked genetic markers to detect population stratification in association studies. Am J Human Genet 1999;65:220-8.
32. Rosenberg NA, Pritchard JK, Weber JL, et al. Genetic structure of human populations. Science 2002;298:2381-5.
33. Gambaro G, Anglani F, D'Angelo A. Association studies of genetic polymorphisms and complex disease. Lancet 2000;355:308-11.
34. Freedman ML, Reich D, Penney KL, et al. Assessing the impact of population stratification on genetic association studies. Nat Genet 2004;36:388-93.
35. [Anon]. Freely associating. Nat Genet 1999;22:1-2.
36. Cardon LR, Bell JI. Association study designs for complex diseases. Nat Rev Genet 2001;2:91-9.
37. Cardon LR, Palmer LJ. Population stratification and spurious allelic association. Lancet 2003;361:598-604.
38. Hirschhorn JN, Lohmueller KE, Pearce CL, et al. Meta-analysis of genetic association studies supports a role for common variants in common disease risk. Am J Human Genet 2002;71:360.
39. Carlborg O, Haley CS. Epistasis: too often neglected in complex trait studies? Nat Rev Genet 2004;5:618-U4.
40. Lohmueller KE, Pearce CL, Pike M, et al. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 2003;33:177-82.
41. Rannala B. Finding genes influencing susceptibility to complex diseases in the post-genome era. Am J Pharmacogenomics 2001;1:203-21.
42. Papapetrou C, Lynch SA, Burn J, et al. Methylenetetrahydrofolate reductase and neural tube defects. Lancet 1996;348:58.
43. Barber R, Shalat S, Hendricks K, et al. Investigation of folate pathway gene polymorphisms and the incidence of neural tube defects in a Texas Hispanic population. Mol Genet Metabol 2000;70:45-52.
44. Barber RC, Rivera-Chavez FA, Horton JW, et al. Hierarchical Bayes resolves the impact of CD14 and TLR4 genotypic interactions on severe sepsis risk after burn injury. Crit Care Med 2003;31:A50.
45. Barber R, Chang L, Arnoldo B, et al. Innate immunity SNPs are associated with risk for severe sepsis after burn injury. Clin Med Res, in press.
46. Barber R, Aragaki C, Chang L, et al. The CD14-159 C-allele is associated with increased risk for mortality after burn injury. Shock, in press.
47. Baratta R, Di Paola R, Spampinato D, et al. Evidence for genetic epistasis in human insulin resistance: the combined effect of PC-1 (K121Q) and PPAR gamma 2 (P12A) polymorphisms. J Mol Med 2003;81:718-23.
48. Bosse Y, Weisnagel SJ, Bouchard C, et al. Combined effects of PPAR gamma(2) P12A and PPAR alpha L162V polymorphisms on glucose and insulin homeostasis: The Quebec Family Study. J Human Genet 2003;48:614-21.
49. Charron S, Duong C, Menard A, et al. Epistasis, not numbers, regulates functions of clustered Dahl rat quantitative trait loci applicable to human hypertension. Hypertension 2005;46:1300-8.
50. Kardia SLR, Bielak LF, Lange LA, et al. Epistatic effects between two genes in the renin-angiotensin system and systolic blood pressure and coronary artery calcification. Medl Sci Monitor 2006;12:CR150-8.
51. Reimold AM. New indications for treatment of chronic inflammation by TNF-alpha blockade. Am J Med Sci 2003;325:75-92.
52. Bosch TM, Meijerman I, Beijnen JH, et al. Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer. Clin Pharmacokinetics 2006;45:253-85.
53. Innocenti F, Iyer L, Ratain MJ. Pharmacogenetics of anticancer agents: lessons from amonafide and irinotecan. Drug Metab Disposition 2001;29:596-600.