Pharmacological characterization of receptor types mediating the dilator action of anandamide on blood vessels of the rat knee joint

Life Sciences

Volumn 80, Issue 16, 2007, Pages 1495-1502

  Lam, Francis F Y ^a   Luk, Phoebe W S ^a   Ng, Ethel S K ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Anandamide; Cannabinoid; TRPV1; Vanilloid; Vasodilatation

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N MORPHOLINO 1H PYRAZOLE 3 CARBOXAMIDE; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; ANANDAMIDE; CAPSAZEPINE; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; FATTY ACID AMIDASE; FLURBIPROFEN; ICOSANOID; N (4 HYDROXYPHENYL)ARACHIDONAMIDE; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ARTICLE; BLOOD FLOW; CONTROLLED STUDY; DOSE RESPONSE; HYDROLYSIS; JOINT CAPSULE; KNEE; MALE; NONHUMAN; PHARMACOLOGICAL PARAMETERS; RAT; VASODILATATION;

AMIDOHYDROLASES; ANALYSIS OF VARIANCE; ANIMALS; ARACHIDONIC ACIDS; BENZAMIDES; BLOOD VESSELS; CAPSAICIN; CARBAMATES; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCANNABINOIDS; FLURBIPROFEN; HINDLIMB; INDOLES; JOINTS; MORPHOLINES; POLYUNSATURATED ALKAMIDES; PYRAZOLES; RATS; RECEPTORS, CANNABINOID; REGIONAL BLOOD FLOW; TRPV CATION CHANNELS; VASODILATION;

RATTUS;

EID: 33947181354     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.01.009     Document Type: Article

References (45)

1. Begg M., Pacher P., Bátkai S., Osei-Hyiaman D., Offertáler L., Mo F.M., Liu J., and Kunos G. Evidence for novel cannabinoid receptors. Pharmacology and Therapeutics 106 2 (2005) 133-145
2. Beltramo M., Stella N., Calignano A., Lin S.Y., Makriyannis A., and Piomelli D. Functional role of high-affinity anandamide transport, as revealed by selective inhibition. Science 277 5329 (1997) 1094-1097
3. Calignano A., La Rana G., Beltramo M., Makriyannis A., and Piomelli D. Potentiation of anandamide hypotension by the transport inhibitor, AM404. European Journal of Pharmacology 337 1 (1997) R1-R2
4. Caterina M.J., Schumacher M.A., Tominaga M., Rosen T.A., Levine J.D., and Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389 6653 (1997) 816-824
5. Chaytor A.T., Martin P.E., Evans W.H., Randall M.D., and Griffith T.M. The endothelial component of cannabinoid-induced relaxation in rabbit mesenteric artery depends on gap junctional communication. The Journal of Physiology 520 Pt 2 (1999) 539-550
6. De Petrocellis L., Bisogno T., Maccarrone M., Davis J.B., Finazzi-Agro A., and Di Marzo V. The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism. Journal of Biological Chemistry 276 16 (2001) 12856-12863
7. Devane W.A., Hanus L., Breuer A., Pertwee R.G., Stevenson L.A., Griffin G., Gibson D., Mandelbaum A., Etinger A., and Mechoulam R. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258 5090 (1992) 1946-1949
8. Di Marzo V., Fontana A., Cadas H., Schinelli S., Cimino G., Schwartz J.C., and Piomelli D. Formation and inactivation of endogenous cannabinoid anandamide in central neurons. Nature 372 6507 (1994) 686-691
9. Di Marzo V., Bisogno T., and De Petrocellis L. Anandamide: some like it hot. Trends in Pharmacological Sciences 22 7 (2001) 346-349
10. Evans R.M., Scott R.H., and Ross R.A. Multiple actions of anandamide on neonatal rat cultured sensory neurones. British Journal of Pharmacology 141 7 (2004) 1223-1233
11. Ferrell W.R., and Lam F.Y. Sensory neuropeptides in arthritis. In: Geppetti P., and Holzer P. (Eds). Neurogenic Inflammation (1996), CRC Press, Boca Raton 211-227
12. Ford W.R., Honan S.A., White R., and Hiley C.R. Evidence of a novel site mediating anandamide-induced negative inotropic and coronary vasodilatator responses in rat isolated hearts. British Journal of Pharmacology 135 5 (2002) 1191-1198
13. Giuffrida A., Beltramo M., and Piomelli D. Mechanisms of endocannabinoid inactivation: biochemistry and pharmacology. The Journal of Pharmacology and Experimental Therapeutics 298 1 (2001) 7-14
14. Grainger J., and Boachie-Ansah G. Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels. British Journal of Pharmacology 134 5 (2001) 1003-1012
15. 2+ influx. British Journal of Pharmacology 139 3 (2003) 585-597
16. Högestätt E.D., and Zygmunt P.M. Cardiovascular pharmacology of anandamide. Prostaglandins, Leukotrienes, and Essential Fatty Acids 66 2-3 (2002) 343-351
17. 2+-induced relaxation. The Journal of Pharmacology and Experimental Therapeutics 289 1 (1999) 245-250
18. 2 receptors. Proceedings of the National Academy of Sciences of the United States of America 96 24 (1999) 14136-14141
19. Jennings E.A., Vaughan C.W., Roberts L.A., and Christie M.J. The actions of anandamide on rat superficial medullary dorsal horn neurons in vitro. The Journal of Physiology 548 Pt 1 (2003) 121-129
20. Jerman J.C., Gray J., Brough S.J., Ooi L., Owen D., Davis J.B., and Smart D. Comparison of effects of anandamide at recombinant and endogenous rat vanilloid receptors. British Journal of Anaesthesia 89 6 (2002) 882-887
21. Jia Y., McLeod R.L., and Hey J.A. TRPV1 receptor: a target for the treatment of pain, cough, airway disease and urinary incontinence. Drug News and Perspectives 18 3 (2005) 165-171
22. Lam F.Y., and Ferrell W.R. Specific neurokinin receptors mediate plasma extravasation in the rat knee joint. British Journal of Pharmacology 103 1 (1991) 1263-1267
23. Lam F.F., and Ng E.S. Characterisation of somatostatin actions on knee joint blood vessels of the rat. European Journal of Pharmacology 474 2-3 (2003) 295-301
24. Lam F.Y., and Wong M.C. Characterization of tachykinin receptors mediating plasma extravasation and vasodilatation in normal and acutely inflamed knee joints of the rat. British Journal of Pharmacology 118 8 (1996) 2107-2114
25. Lam F.F.Y., Wong H.H.L., and Ng E.S.K. Time course and substance P effects on the vascular and morphological changes in adjuvant-induced monoarthritic rats. International Immunopharmacology 4 2 (2004) 299-310
26. 1 cannabinoid receptors in human vascular endothelial cells. The Biochemical Journal 346 Pt 3 (2000) 835-840
27. Mukhopadhyay S., Chapnick B.M., and Howlett A.C. Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent. American Journal of Physiology. Heart and Circulatory Physiology 282 6 (2002) H2046-H2054
28. Offertáler L., Mo F.M., Batkai S., Liu J., Begg M., Razdan R.K., Martin B.R., Bukoski R.D., and Kunos G. Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor. Molecular Pharmacology 63 3 (2003) 469-470
29. Olah Z., Karai L., and Iadarola M.J. Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1. Journal of Biological Chemistry 276 33 (2001) 31163-31170
30. Piomelli D., Tarzia G., Duranti A., Tontini A., Mor M., Compton T.R., Dasse O., Monaghan E.P., Parrot J.A., and Putman D. Pharmacological profile of the selective FAAH inhibitor KDS-4103 (URB597). CNS Drug Review 12 1 (2006) 21-38
31. Randall M.D., Kendall D.A., and O'Sullivan S. The complexities of the cardiovascular actions of cannabinoids. British Journal of Pharmacology 142 1 (2004) 20-26
32. Ralevic V., Kendall D.A., Randall M.D., and Smart D. Cannabinoid modulation of sensory neurotransmission via cannabinoid and vanilloid receptors: roles in regulation of cardiovascular function. Life Sciences 71 22 (2002) 2577-2594
33. Richardson J.D., Aanonsen L., and Hargreaves K.M. Antihyperalgesic effects of spinal cannabinoids. European Journal of Pharmacology 345 2 (1998) 145-153
34. 1 receptors, nitric oxide and potassium channels. British Journal of Pharmacology 147 8 (2006) 917-925
35. Smart D., and Jerman J.C. Anandamide: an endogenous activator of the vanilloid receptor. Trends in Pharmacological Sciences 21 4 (2000) 134
36. Szallasi A., and Blumberg P.M. Resiniferatoxin and its analogs provide novel insights into the pharmacology of the vanilloid (capsaicin) receptor. Life Sciences 47 16 (1990) 1399-1408
37. Varga K., Wagner J.A., Bridgen D.T., and Kunos G. Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. The FASEB Journal 12 11 (1998) 1035-1044
38. 1 cannabinoid receptors in haemorrhagic shock. Nature 390 6659 (1997) 518-521
39. Wagner J.A., Varga K., Jarai Z., and Kunos G. Mesenteric vasodilation mediated by endothelial anandamide receptors. Hypertension 33 1 (1999) 429-434
40. Wagner J.A., Jarai Z., Batkai S., and Kunos G. Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors. European Journal of Pharmacology 423 2-3 (2001) 203-210
41. White R., Ho, and Hiley C.R. A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. British Journal of Pharmacology 122 8 (1997) 1573-1584
42. White R., Ho W.S., Bottrill F.E., Ford W.R., and Hiley C.R. Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries. British Journal of Pharmacology 134 4 (2001) 921-929
43. 2. Journal of Lipid Research 46 12 (2005) 2745-2751
44. Zygmunt P.M., Petersson J., Andersson D.A., Chuang H., Sorgard M., Di Marzo V., Julius D., and Högestätt E.D. Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 400 6743 (1999) 452-457
45. Zygmunt P.M., Chuang H., Movahed P., Julius D., and Högestätt E.D. The anandamide transport inhibitor AM404 activates vanilloid receptors. European Journal of Pharmacology 396 1 (2000) 39-42