Invited review: Origin of monocytes and their differentiation to macrophages and dendritic cells

Journal of Endotoxin Research

Volumn 12, Issue 5, 2006, Pages 278-284

  Kumar, Suresh ^a   Jack, Robert ^a  

^a UNIVERSITY MEDICINE GREIFSWALD   (Germany)

Author keywords

Dendritic cells; Macrophages; Monocytes; Mononuclear phagocytes

Indexed keywords

CD45 ANTIGEN; CHEMOKINE RECEPTOR; COLONY STIMULATING FACTOR 1; CX3CR1 CHEMOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 15; INTERLEUKIN 4; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR PAX5; UNCLASSIFIED DRUG;

CELL ADHESION; CELL DIFFERENTIATION; CELL FATE; CELL HETEROGENEITY; CELL INTERACTION; DENDRITIC CELL; GENETIC CODE; GENETIC STABILITY; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNE RESPONSE; IN VITRO STUDY; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; MONOCYTE; MONONUCLEAR PHAGOCYTE; NONHUMAN; PHENOTYPE; REVIEW; PHYSIOLOGY;

CELL DIFFERENTIATION; DENDRITIC CELLS; MACROPHAGES; MONOCYTES;

EID: 33947142356     PISSN: 09680519     EISSN: None     Source Type: Journal    
DOI: 10.1177/09680519060120050301     Document Type: Review

References (56)

1. Caramalho I., Lopes-Carvalho T., Ostler D., Zelenay S., Haury M., Demengeot J. Regulatory T cells selectively express Toll-like receptors and are activated by lipopolysaccharide. J Exp Med 2003; 197: 403-411.
2. Pasare C., Medzhitov R. Control of B-cell responses by Toll-like receptors. Nature 2005; 438:364- 368.
3. Rakoff-Nahoum S., Paglino J., Eslami-Varzaneh F., Edberg S., Medzhitov R. Recognition of commensal microflora by Toll-like receptors is required for intestinal homeostasis. Cell 2004; 118: 229-241.
4. Akira S., Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004; 4: 499-511.
5. Zhang M., Tang H., Guo Z. et al. Splenic stroma drives mature dendritic cells to differentiate into regulatory dendritic cells. Nat Immunol 2004; 5: 1124-1133.
6. Sallusto F., Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/ macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med 1994; 179: 1109-1118.
7. Alferink J., Lieberam I., Reindl W. et al. Compartmentalized production of CCL17 in vivo: Strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen. J Exp Med 2003; 197: 585-599.
8. Akashi K., Traver D., Zon LI The complex cartography of stem cell commitment. Cell 2005; 121: 160-162.
9. Christensen JL, Weissman IL Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells. Proc Natl Acad Sci USA 2001; 98: 14541-14546.
10. Adolfsson J., Mansson R., Buza-Vidas N. et al. Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell 2005; 121: 295-306.
11. Kondo M., Weissman IL, Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997; 91: 661-672.
12. Akashi K., Traver D., Miyamoto T., Weissman IL A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 2000; 404: 193-197.
13. Nutt SL, Heavey B., Rolink AG, Busslinger M. Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature 1999; 401: 556-562.
14. Rolink AG, Nutt SL, Melchers F., Busslinger M. Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors [see comments]. Nature 1999; 401: 603-606.
15. Mikkola I., Heavey B., Horcher M., Busslinger M. Reversion of B cell commitment upon loss of Pax5 expression. Science 2002; 297: 110-113.
16. Traver D., Akashi K., Manz M. et al. Development of CD8alpha-positive dendritic cells from a common myeloid progenitor. Science 2000; 290: 2152-2154.
17. Karsunky H., Merad M., Cozzio A., Weissman IL, Manz MG Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo. J Exp Med 2003; 198: 305-313.
18. Shigematsu H., Reizis B., Iwasaki H. et al. Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin. Immunity 2004; 21: 43-53.
19. Fogg DK, Sibon C., Miled C. et al. A clonogenic bone marrow progenitor specific for macrophages and dendritic cells. Science 2006; 311: 83-87.
20. Jung S., Aliberti J., Graemmel P. et al. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol 2000; 20: 4106-4114.
21. Geissmann F., Jung S., Littman DR Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 2003; 19: 71-82.
22. Mohamadzadeh M., Berard F., Essert G. et al. Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cells. J Exp Med 2001; 194: 1013-1020.
23. Krutzik SR, Tan B., Li H. et al. TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells. Nat Med 2005; 11: 653-660.
24. Chomarat P., Banchereau J., Davoust J., Karolina Palucka A. IL-6 switches the differentiation of monocytes from dendritic cells to macrophages. Nat Immunol 2000; 1: 510-514.
25. Gordon S. Alternative activation of macrophages. Nat Rev Immunol 2003; 3: 23-35.
26. Rauh MJ, Ho V., Pereira C. et al. SHIP represses the generation of alternatively activated macrophages. Immunity 2005; 23: 361-374.
27. Hacker C., Kirsch RD, Ju X-S. et al. Transcriptional profiling identifies Id2 function in dendritic cell development. Nat Immunol 2003; 4: 380-386.
28. Stein M., Keshav S., Harris N., Gordon S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation. J Exp Med 1992; 176: 287-292.
29. Springer TA Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell 1994; 76: 301-314.
30. Reymond N., Imbert AM, Devilard E. et al. DNAM-1 and PVR regulate monocyte migration through endothelial junctions. J Exp Med 2004; 199: 1331-1341.
31. Schenkel AR, Mamdouh Z., Chen X., Liebman RM, Muller WA CD99 plays a major role in the migration of monocytes through endothelial junctions. Nat Immunol 2002; 3: 143-150.
32. Muller WA, Weigl SA, Deng X., Phillips DM PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med 1993; 178: 449-460.
33. Ostermann G., Weber KS, Zernecke A., Schroder A., Weber C. JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes. Nat Immunol 2002; 3: 151-158.
34. Wojciak-Stothard B., Williams L., Ridley AJ Monocyte adhesion and spreading on human endothelial cells is dependent on Rho-regulated receptor clustering. J Cell Biol 1999; 145: 1293-1307.
35. Worthylake RA, Lemoine S., Watson JM, Burridge K. RhoA is required for monocyte tail retraction during transendothelial migration. J Cell Biol 2001; 154: 147-160.
36. Imhof BA, Aurrand-Lions M. Adhesion mechanisms regulating the migration of monocytes. Nat Rev Immunol 2004; 4: 432-444.
37. Randolph GJ, Beaulieu S., Lebecque S., Steinman RM, Muller WA Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking. Science 1998; 282: 480-483.
38. Serbina NV, Pamer EG Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat Immunol 2006; 7: 311-317.
39. Volkman A., Gowans JL The origin of macrophages from bone marrow in the rat. Br J Exp Pathol 1965;46: 62-72.
40. van Furth R., Cohn ZA The origin and kinetics of mononuclear phagocytes. J Exp Med 1968; 128: 415-435.
41. Passlick B., Flieger D., Ziegler-Heitbrock L. Identification and characterisation of a novel monocyte subpopulation in human peripheral blood. Blood 1989; 74: 2527-2534.
42. + blood monocytes is expanded in sepsis patients. Blood 1993; 82:3170-3176.
43. + monocytes by glucocorticoid therapy. Clin Exp Immunol 1998; 112: 501-506.
44. Randolph GJ, Sanchez-Schmitz G., Liebman RM, Schakel K. The CD16(+) (FcgammaRIII(+)) subset of human monocytes preferentially becomes migratory dendritic cells in a model tissue setting. J Exp Med 2002; 196: 517-527.
45. Butcher EC, Picker LJ Lymphocyte homing and homeostasis. Science 1996; 272: 60-66.
46. Palframan RT, Jung S., Cheng G. et al. Inflammatory chemokine transport and presentation in HEV: A remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues. J Exp Med 2001; 194: 1361-1374.
47. Merad M., Manz MG, Karsunky H. et al. Langerhans cells renew in the skin throughout life under steady-state conditions. Nat Immunol 2002; 3: 1135-1141.
48. Ginhoux F., Tacke F., Angeli V. et al. Langerhans cells arise from monocytes in vivo. Nat Immunol 2006; 7: 265-273.
49. Srivastava M., Jung S., Wilhelm J. et al. The inflammatory versus constitutive trafficking of mononuclear phagocytes into the alveolar space of mice is associated with drastic changes in their gene expression profiles. J Immunol 2005; 175: 1884-1893.
50. Poltorak A., He X., Smirnova I. et al. Defective LPS signaling in C3H/ HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene. Science 1998; 282: 2085-2088.
51. Medzhitov R., Preston-Hurlburt P., Janeway Jr CA. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity [see comments]. Nature 1997; 388: 394-397.
52. Janeway Jr CA, Medzhitov R. Innate immune recognition. Annu Rev Immunol 2002; 20: 197-216.
53. Smythies LE, Sellers M., Clements RH et al. Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity. J Clin Invest 2005; 115: 66-75.
54. Rotta G., Edwards EW, Sangaletti S. et al. Lipopolysaccharide or whole bacteria block the conversion of inflammatory monocytes into dendritic cells in vivo. J Exp Med 2003; 198: 1253-1263.
55. Fortsch D., RollinghoffM, Stenger S. IL-10 converts human dendritic cells into macrophage-like cells with increased antibacterial activity against virulent Mycobacterium tuberculosis. J Immunol 2000; 165: 978-987.
56. Stout RD, Jiang C., Matta B., Tietzel I., Watkins SK, Suttles J. Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J Immunol 2005; 175: 342-349.