Elimination of polychlorinated dibenzo-p-dioxins and dibenzofurans in occupationally exposed persons

Journal of Toxicology and Environmental Health - Part A

Volumn 47, Issue 4, 1996, Pages 363-378

  Flesch Janys, D ^a   Becher, H ^b   Gurn, P ^a   Jung, D ^c   Konietzko, J ^c   Manz, A ^a   Papke O ^d  

^a Med Ctr for Chem Workers' Health   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

^d ERGO Forschungsgesellschaft mbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

POLYCHLORINATED DIBENZODIOXIN; POLYCHLORINATED DIBENZOFURAN;

ADULT; ARTICLE; BLOOD LEVEL; CLINICAL ARTICLE; FEMALE; HUMAN; MALE; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; TOXICOKINETICS;

ADIPOSE TISSUE; ADULT; BENZOFURANS; CHOLESTEROL; DATA INTERPRETATION, STATISTICAL; DIOXINS; FEMALE; HALF-LIFE; HUMANS; MALE; MIDDLE AGED; MODELS, STATISTICAL; OCCUPATIONAL EXPOSURE; SMOKING; TETRACHLORODIBENZODIOXIN; TIME FACTORS;

EID: 0029940875     PISSN: 15287394     EISSN: None     Source Type: Journal    
DOI: 10.1080/009841096161708     Document Type: Article

References (23)

1. Getchell, M. L., Chun, Y., Ding, X., Sparks, D. L., and Getchell, T. V. 1993. Immunohistochemical localization of a cytochrome P450 isozyme in human nasal mucosa: age related trends. Ann. Otol. Rhinol. Laryngol. 102:368-374.
2. Geyer, H. J., Scheunert, I., and Kettrup, A. 1991. A new approach in estimating the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) to humans. Dioxin '91 (abstr.). Chapel Hill, NC.
3. Gorski, T., Konopka, L., and Brodzki, M. 1984. Persistence of some polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans of pentachlorophenol in human adipose tissue. Roczn. Pzh. T. 35:297.
4. Gurn, P., Beck, H., Flesch-Janys, D., Jung, D., Konietzko, J., Manz, A., Mathar, W., and Päpke, O. 1995. Partitioning of PCDD/Fs between blood and adipose tissue in 9 former chemical workers. Organohalogen Comp. 26:233-238.
5. Hayashi, S., Watanabe, J., Nakachi, K., Eguchi, H., Gotoh, O., and Kawajari, K. 1994. Interindividual difference in expression of human Ah-receptor and related P450 genes. Carcinogenisis 15:801-806.
6. Knapik, J. J., Burse, R. L., and Vogel, J. A. 1983. Height, weight percent body fat and indices of adiposity for young men and women entering the U.S. Army. Aviat. Space Environ. Med. 54:223-231.
7. Manz, A., Berger, J., Dwyer, J. H., Flesch-Janys, D., Nagel, S., and Waltsgott, H. 1991. Cancer mortality among workers in a chemical plant contaminated with dioxin. Lancet 338:959-964.
8. Michalek, J. E., Tripathi, R. C., Caudill, S. P., and Pirkle, J. L. 1992. Investigation of TCDD half-life heterogeneity in veterans of operation Ranch Hand. J. Toxicol. Environ. Health. 35:29-38.
9. Needham, L. L., Gerthoux, P. M., Patterson, D. G., Jr., Brambilla, P., Pirkle, J. L., Tramacere, P. L., Turner, W. E., Beretta, C., Sampson, E. J., and Mocarelli, P. 1994. Half-life of 2,3,7,8-tetrachlorodibenzo-p-dioxin in serum of Seveso adults: Interim report. Organohalogen Compounds 21:81-85.
10. Pirkle, J. L., Wolfe, W. H., Patterson, D. G., Needham, L. L., Michalek, J. E., Miner, J. C., Peterson, M. R., and Phillips, D. L. 1989. Estimates of the half-life of 2,3,7,8-tetrachlorodibenzo-p-dioxin in Vietnam veterans of operation Ranch Hand. J. Toxicol. Environ. Health 27:165-171.
11. Päpke, O., Ball, M., and Lis, A. 1994. PCDD/PCDF in humans, a 1993 update of background data. Chemosphere 29:2355-2360.
12. Rat der Sachverständigen für Umweltfragen. 1988. Umweltgutachten 1987. Stuttgart und Mainz: Verlag W. Kohlhammer.
13. Ryan, J. J., and Masuda, Y. 1991. Elimination of polychlorinated dibenzofurans (PCDFs) in humans from the Yusho and Yucheng rice oil poisonings. Dioxin '91 (abstr.), Chapel Hill, NC.
14. Schecter, A., and Ryan, J. J. 1991. Dioxin and dibenzofuran levels in exposed workers: a) Serial dioxin and dibenzofuran blood and adipose tissue levels in a worker exposed in a PCB transformer fire cleanup b) Blood levels of dioxins and dibenzofurans in two exposed chemists. Dioxin '91 (abstr.), Chapel Hill, NC.
15. Schecter, A., Ryan, J. J., and Kostyniak, P. J. 1 990. Decrease over a six year period of dioxin and dibenzufuran tissue levels in a single patient following exposure. Chemosphere 20:911-917.
16. Schlatter, C. 1991. Data on kinetics of PCDDs and PCDFs as a preerequisite for human risk assessment. In Biologic basis for risk assessment of dioxins and related compounds, eds. M. A. Gallo, R. J. Scheuplein, and K. A. Van der Heiden, pp. 215-226. Cold Spring Harbor, NY: Cold Spring Harbor Press.
17. Stephens, R. D., Rappe, C., Hayward, D. G., Nygren, M., Startin, J., Esboll, A., Carlé, J., and Yrjänhheikki, E. 1992. World Health Organization international intercalibration study on dioxins and furans in human milk and blood. Anal. Chem. 64:3109-3117.
18. Van den Berg, M., De Jongh, J., Poiger, H., and Olson, J. R. 1994. The toxicokinetics and metabolism of polychlorinated dibenzo-p-dixoins (PCDDs) and dibenzofurans (PCDFs) and their relevance for toxicity. Crit. Rev. Toxicol. 24:1-74.
19. WHO Regional Office for Europe. 1992. Consultation on the third round of interlaboratory quality control studies on levels of PCBs, PCDDs and PCDFs in human milk, blood, cow's milk and fish. Volterra, Italy, October 13-16.
20. Wolfe, W. H., Michalek, J. E., Miner, J. C., Pirkle, J. L., Caudill, S. P., Patterson, D. G., Jr., and Needham, L. L. 1994. Determinants of TCDD half-life in veterans of operation Ranch Hand. J. Toxicol. Environ. Health 41:481-488.
21. Wolff, T., and Strecker, M. 1992. Endogenous and exogenous factors modifying the activity of human liver cytochrome P450 enzymes. Exp. Toxicol. Pathol. 44:263-271.
22. Yrjanheikki, E. (ed.) 1991. Levels of PCB's, PCDD's and PCDF's in human milk and blood: Second round of quality control studies. In Environment and Health in Europe. Copenhagen: WHO.
23. Zannikos, P. N., Bandyopadhyay, A. M., Robertson, L. W., and Blowin, R. A. 1993. Effect of nutritional obesity on the induction of CYP2B enzymes. Drug Metab. Dispos. 21:782-787.