Safety of intrastriatal neurotransplantation for Huntington's disease patients

Experimental Neurology

Volumn 149, Issue 1, 1998, Pages 97-108

  Kopyov, O V ^a   Jacques, S ^a   Lieberman, A ^b   Duma, C M ^a   Eagle, K S ^a  

^a GOOD SAMARITAN HOSPITAL   (United States)

^b BARROW NEUROLOGICAL INSTITUTE   (United States)

Author keywords

Fetal transplantation; Huntington's disease; Lateral ganglionic eminence; Magnetic resonance imaging; Neurotransplantation

Indexed keywords

ADULT; ARTICLE; CASE REPORT; CORPUS STRIATUM; FETAL TISSUE TRANSPLANTATION; GRAFT SURVIVAL; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; MALE; NERVE TRANSPLANTATION; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

EID: 0031887047     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1997.6685     Document Type: Article

References (51)

1. Bjorklund A., Campbell K., Sinathsinghji R. A., Fricker R. A., Dunnett S. B. Functional capacity of striatal transplants in the rat Huntington model. Functional Neural Transplantation. 1994;Raven Press, New York. p. 157-195.
2. Browne S. E., Beal M. F. Oxidative damage and mitochondrial dysfunction in neurodegenerative diseases. Biochem. Soc. Trans. 22:1994;1002-1006.
3. Browne S. E., Bowling A. C., Macgarvey U., Baik M. J., Berger S. C., Muqit M. M., Bird E. D., Beal M. F. Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia. Ann. Neurol. 41:1997;646-653.
4. Carella F., Scaioli V., Ciano C., Binelli S., Oliva D., Girotti F. Adult onset myoclonic Huntington's disease. Mov. Disord. 8:1993;201-205.
5. Cools A., Van Den Bercken J., Horsteink M. The basal ganglia and the programming of behavior. Trends. Neurosci. 4:1981;124.
6. Deacon T. W., Pakzaban P., Isacson O. The lateral ganglionic eminence is the origin of cells committed to striatal phenotypes: Neural transplantation and developmental evidence. Brain Res. 668:1994;211-219.
7. Denys A., Leroy-Willig A., Riche D., Hantraye P. MR appearance of neural grafts in a primate model of Huntington disease. Am. J. Roentgenol. 158:1992;215-216.
8. Freed C. R., Breeze R. E., Rosenberg N. L., Schneck S. A., Kriek E., Qi J. X., Lone T., Zhang Y. B., Snyder J. A., Wells T. H. Survival of implanted fetal dopamine cells and neurologic improvement 12 to 46 months after transplantation for Parkinson's disease. N. Engl. J. Med. 327:1992;1549-1555.
9. Freeman T. B., Olanow C. W., Hauser R. A., Nauert G. M., Smith D. A., Borlongan C. V., Sanberg P. R., Holt D. A., Kordower J. H., Vingerhoets F. J. Bilateral fetal nigral transplantation into the postcommissural putamen in Parkinson's disease. Ann. Neurol. 38:1995;379-388.
10. Grafton S. T., Mazziota J. C., Pahl J. J., St P., Haines J. L., Gusella J., Hoffman J. M., Baxter L. R., Phelps M. E. Serial changes of cerebral glucose metabolism and caudate size in persons at risk for Huntington's disease. Arch. Neurol. 49:1992;1161-1167.
11. Grasbon-Frodl E. M., Nakao N., Lindvall O., Brundin P. Phenotypic development of the human embryonic striatal primordium: A study of cultured and grafted neurons from the lateral and medial ganglionic eminences. Neuroscience. 73:1996;171-183.
12. Grasbon-Frodl E. M., Nakao N., Lindvall O., Brundin P. Developmental features of human striatal tissue transplanted in a rat model of Huntington's disease. Neurobiol. Dis. 3:1997;299-311.
13. Hayden M. R., Hewitt J., Stoessl A. J., Clark C., Ammann W., Martin W. R. The combined use of positron emission tomography and DNA polymorphisms for preclinical detection of Huntington's disease. Neurology. 37:1987;1441-1447.
14. Hayden M. R., Martin W. R., Stoessl A. J. Positron emission tomography in the early diagnosis of Huntington's disease. Neurology. 36:1986;888-894.
15. Hikosaka O., Sakamoto M., Usui S. Functional properties of monkey caudate neurons. III. Activities related to expectation of target and reward. J Neurophysiol. 61:1989;814-832.
16. Mov. Disord. 11:1996;136-142.
17. Isacson O., Brundin P., Gage F. H., Bjorklund A. Neural grafting in a rat model of Huntington's disease: Progressive neurochemical changes after neostriatal ibotenate lesions and striatal tissue grafting. Neuroscience. 16:1985;799-817.
18. Isacson O., Dunnett S. B., Bjorklund A. Graft-induced behavioral recovery in an animal model of Huntington disease. Proc. Natl. Acad. Sci. USA. 83:1986;2728-2732.
19. Jeanty P., Romero R. Obstetrical Ultrasound. 1984;McGraw-Hill, New York.
20. Kopyov O. V., Jacques D., Lieberman A., Duma C. M., Rogers R. L. Clinical study of fetal mesencephalic intracerebral transplants for the treatment of Parkinson's disease. Cell Transplant. 5:1996;327-337.
21. Kopyov O. V., Jacques D. S., Lieberman A., Duma C. M., Rogers R. L. Outcome following intrastriatal fetal mesencephalic grafts for Parkinson's patients is directly related to the volume of grafted tissue. Exp. Neurol. 146:1997;536-545.
22. Kopyov, O. V. M. Kurth, D. B. Jacques, L. Philpott, A. M. Lee, M. Patterson, C. Duma, E. Kogosov, A. Lieberman, K. S. Eagle, 1997, Neurotransplantation of fetal lateral ganglionic eminence tissue in three patients with Huntington's disease, Society for Neuroscience 26th Annual Meeting.
23. Kordower J. H., Freeman T. B., Snow B. J., Vingerhoets F. J., Mufson E. J., Sanberg P. R., Hauser R. A., Smith D. A., Nauert G. M., Perl D. P. Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease. N. Engl. J. Med. 332:1995;1118-1124.
24. Kordower J. H., Rosenstein J. M., Collier T. J., Burke M. A., Chen E. Y., Li J. M., Martel L., Levey A. E., Mufson E. J., Freeman T. B., Olanow C. W. Functional fetal nigral grafts in a patient with Parkinson's disease: Chemoanatomic, ultrastructural, and metabolic studies. J. Comp. Neurol. 370:1996;203-230.
25. Kuhl D. E., Phelps M. E., Markham C. H., Metter E. J., Riege W. H., Winter J. Cerebral metabolism and atrophy in Huntington's disease determined by 18FDG and computed tomographic scan. Ann. Neurol. 12:1982;425-434.
26. Lindvall O. Neural transplantation. Cell Transplant. 4:1995;393-400.
27. Lindvall O., Brundin P., Widner H., Rehncrona S., Gustavii B., Frackowiak R., Leenders K. L., Sawle G., Rothwell J. C., Marsden C. D. Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease. Science. 247:1990;574-577.
28. Lindvall O., Rehncrona S., Brundin P., Gustavii B., Astedt B., Widner H., Lindholm T., Bjorklund A., Leenders K. L., Rothwell J. C. Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease: A detailed account of methodology and a 6-month follow-up. Arch. Neurol. 46:1989;615-631.
29. Marsden C. D. Movement disorders and the basal ganglia. Trends. Neurosci. 9:1986;512-515.
30. Naimi S., Jeny R., Hantraye P., Peschanski M., Riche D. Ontogeny of human striatal DARPP-32 neurons in fetuses and following xenografting to the adult rat brain. Exp. Neurol. 137:1996;15-25.
31. Nakao N., Brundin P., Funa K., Lindvall O., Odin P. Platelet-derived growth factor exerts trophic effects on rat striatal DARPP-32-containing neurons in culture. Exp. Brain Res. 101:1994;291-296.
32. O'Rahilly R., Muller F. The Embryonic Human Brain: An Atlas of Developmental Stages. 1994;Wiley- Liss, New York.
33. Oberg R. E., Divac I. Levels of motor planning: Cognition and the control of movement. Trends. Neurosci. 4:1981;122-124.
34. Olanow C. W., Kordower J. H., Freeman T. B. Fetal nigral transplantation as a therapy for Parkinson's disease. Trends. Neurosci. 19:1996;102-109.
35. Pakzaban P., Deacon T. W., Burns L. H., Isacson O. Increased proportion of acetylcholinesterase-rich zones and improved morphological integration in host striatum of fetal grafts derived from the lateral but not the medial ganglionic eminence. Exp. Brain Res. 97:1993;13-22.
36. Peschanski M., Cesaro P., Hantraye P. Rationale for intrastriatal grafting of striatal neuroblasts in patients with Huntington's disease. Neuroscience. 68:1995;273-285.
37. Philpott L. M., Kopyov O. V., Lee A. J., Jacques S., Duma C. M., Caine S., Yang M., Eagle K. S. Neuropsychological functioning following fetal striatal transplantation in Huntington's chorea: Three case presentations. Cell Transplant. 6:1997;203-212.
38. Pundt L. L., Kondoh T., Conrad J. A., Low W. C. Transplantation of human fetal striatum into a rodent model of Huntington's disease ameliorates locomotor deficits. Neurosci. Res. 24:1996;415-420.
39. Pundt L. L., Kondoh T., Conrad J. A., Low W. C. Transplantation of human striatal tissue into a rodent model of Huntington's disease: Phenotypic expression of transplanted neurons and host-to-graft innervation. Brain Res. Bull. 39:1996;23-32.
40. Pundt L. L., Kondoh T., Low W. C. NADPH-diaphorase histochemistry and functional analysis of human fetal striatal brain tissue transplanted into a rodent model of Huntington's disease. Transplant. Proc. 26:1994;3295.
41. Pundt L. L., Narang N., Kondoh T., Low W. C. Localization of dopamine receptors and associated mRNA in transplants of human fetal striatal tissue in rodents with experimental Huntington's disease. Neurosci. Res. 27:1997;305-315.
42. Quinn N., Brown R., Craufurd D., Goldman S., Hodges J., Kieburtz K., Lindvall O., Macmillan J., Roos R. Core Assessment Program for Intracerebral Transplantation in Huntington's Disease (CAPIT-HD). Mov. Disord. 11:1996;143-150.
43. Sanberg P. R., Koutouzis T. K., Freeman T. B., Cahill D. W., Norman A. B. Behavioral effects of fetal neural transplants: Relevance to Huntington's disease. Brain Res. Bull. 32:1993;493-496.
44. Shannon K. M., Kordower J. H. Neural transplantation for Huntington's disease: Experimental rationale and recommendations for clinical trials. Cell Transplant. 5:1996;339-352.
45. Simmons N. E., Helm G. A., Cail W. S., Bennett J. P., Jane J. A. Magnetic resonance imaging of neuronal grafts in the primate. Exp. Neurol. 125:1994;52-57.
46. Sinden J. D., Patel S. N., Hodges H. Neural transplantation: Problems and prospects for therapeutic application. Curr. Opin. Neurol. Neurosurg. 5:1992;902-908.
47. Spencer D. D., Robbins R. J., Naftolin F., Marek K. L., Vollmer T., Leranth C., Roth R. H., Price L. H., Gjedde A., Bunney B. S. Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease. N. Engl. J. Med. 327:1992;1541-1548.
48. Thompson P. D., Bhatia K. P., Brown P., Davis M. B., Pires M., Quinn N. P., Luthert P., Honovar M., O'Brien M. D., Marsden C. D. Cortical myoclonus in Huntington's disease. Mov. Disord. 9:1994;633-641.
49. Vogel C. M., Drury I., Terry L. C., Young A. B. Myoclonus in adult Huntington's disease. Ann. Neurol. 29:1991;213-215.
50. Wenning G. K., Odin P., Morrish B. M., Rehncrona S., Widner H., Brundin P., Rothwell J. C., Brown R., Gustavii B., Hagell P., Jahanshahi M., Sawle G., Bjorklund A., Brooks D. J., Marsden C. D., Quinn N. P., Lindvall O. Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease. Ann. Neurol. 42:1997;95-107.
51. Wictorin K., Isacson O., Fischer W., Nothias F., Peschanski M., Bjorklund A. Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum. I. Subcortical afferents. Neuroscience. 27:1988;547-562.