Histological analysis of fetal dopamine cell suspension grafts in two patients with Parkinson's disease gives promising results

Brain

Volumn 128, Issue 7, 2005, Pages 1478-1479

  Kirik, Deniz ^a   Björklund, Anders ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CALBINDIN; CALCIUM BINDING PROTEIN; DOPA; HLA ANTIGEN CLASS 1; IMMUNOSUPPRESSIVE AGENT; PROTEIN; PROTEIN GIRK2; UNCLASSIFIED DRUG; DOPAMINE;

ADOPTIVE IMMUNOTHERAPY; BRAIN TRANSPLANTATION; CAPILLARY; CELL SUSPENSION; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; DYSKINESIA; FETUS (ANATOMY); GRAFT REJECTION; GRAFT SURVIVAL; HISTOPATHOLOGY; HUMAN; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; MESENCEPHALON; NOTE; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUTAMEN; SUBSTANTIA NIGRA; VENTRAL TEGMENTUM; ALLOTRANSPLANTATION; AUTOPSY; BRAIN; FETAL TISSUE TRANSPLANTATION; IMMUNOLOGY; NERVE CELL; PATHOLOGY; PHYSIOLOGY; PRENATAL DEVELOPMENT; TRANSPLANTATION; TREATMENT OUTCOME;

AUTOPSY; BRAIN; BRAIN TISSUE TRANSPLANTATION; CORPUS STRIATUM; DOPAMINE; FETAL TISSUE TRANSPLANTATION; GRAFT SURVIVAL; HUMANS; MESENCEPHALON; NEURONS; PARKINSON DISEASE; SUBSTANTIA NIGRA; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME;

EID: 21944446706     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/awh570     Document Type: Note

References (4)

1. Freed CR, Greene PE, Breeze RE, Tsai WY, DuMouchel W, Kao R, et al. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med 2001; 344: 710-719.
2. Lindvall O, Bjorklund A. Cell therapy in Parkinson's disease. Neurorx 2004; 1: 382-393.
3. Olanow CW, Goetz CG, Kordower JH, Stoessl AJ, Sossi V, Brin MF, et al. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease. Ann Neurol 2003; 54: 403-414.
4. Winkler C, Kirik D, Bjorklund A. Cell transplantation in Parkinson's disease: how can we make it work? Trends Neurosci 2005; 28: 86-92.