Synergistic combinations of anticonvulsant agents: What is the evidence from animal experiments?

Epilepsia

Volumn 48, Issue 3, 2007, Pages 412-434

  Jonker, Daniël M ^a,b   Voskuyl, Rob A ^a,b   Danhof, Meindert ^a,c  

^a LEIDEN UNIVERSITY   (Netherlands)

^b STICHTING EPILEPSIE INSTELLINGEN NEDERLAND SEIN   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Combination; Epilepsy; Interaction mechanism; Literature analysis; Synergism

Indexed keywords

1 (4 AMINOPHENYL) 4 METHYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; 1 [2 [TRIS(4 METHOXYPHENYL)METHYL]ETHYL] 3 PIPERIDINECARBOXYLIC ACID; 2 AMINO 4 METHYL 5 PHOSPHONO 3 PENTENOIC ACID; 2 AMINO 4 METHYL 5 PHOSPHONO 3 PENTENOIC ACID ETHYL ESTER; 2 AMINO 5 PHOSPHONOVALERIC ACID; 2 AMINOADIPIC ACID; 2 CA; 2 METHYL 6 (2 PHENYLVINYL)PYRIDINE; 3 AMINOPROPYLBUTYLPHOSPHINIC ACID; 4 (2H TETRAZOL 5 YLMETHYL) 2 PIPERIDINECARBOXYLIC ACID; 8 CPX; AMPA RECEPTOR ANTAGONIST; ANTICONVULSIVE AGENT; APOMORPHINE; BACLOFEN; CARBAMAZEPINE; CFM 2; CHLORDIAZEPOXIDE; CLOBAZAM; CLONAZEPAM; CO 2 1068; DECAHYDRO 6 PHOSPHONOMETHYL 3 ISOQUINOLINECARBOXYLIC ACID; DIAZEPAM; DIZOCILPINE; EGLUMETAD; FLUNITRAZEPAM; GABOXADOL; GLUTAMIC ACID DIETHYL ESTER; GLYCINE; LEVODOPA; MUSCIMOL; NICOTINAMIDE; NNC 05 2045; OXAMIC ACID; OXAZEPAM; OXCARBAZEPINE; OXIRACETAM; PHENOBARBITAL; PHENYTOIN; PIRACETAM; PROGABIDE; TOFISOPAM; TRIAZOLAM; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID;

AMYGDALOID NUCLEUS; ANTICONVULSANT THERAPY; BRAIN DEPTH STIMULATION; CONVULSION; DOSE RESPONSE; DRUG ANTAGONISM; DRUG BRAIN LEVEL; DRUG POTENTIATION; ELECTRIC SHOCK; EPILEPTIC STATE; EX VIVO STUDY; EXPERIMENTAL MODEL; IN VIVO STUDY; INTERMETHOD COMPARISON; KINDLING; MEDICAL LITERATURE; NONHUMAN; PRIORITY JOURNAL; PUBLICATION; REVIEW; SEIZURE THRESHOLD;

AMYGDALA; ANIMALS; ANTICONVULSANTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; ELECTROSHOCK; EPILEPSY; HUMANS; ION CHANNELS; KINDLING, NEUROLOGIC; LOGISTIC MODELS; PENTYLENETETRAZOLE; RECEPTORS, NEUROTRANSMITTER; RESEARCH DESIGN;

EID: 33847639380     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2006.00952.x     Document Type: Review

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