Effect of sodium valproate and flunarizine administered alone and in combination on pentylenetetrazole model of absence seizures in rat

Indian Journal of Experimental Biology

Volumn 37, Issue 3, 1999, Pages 228-233

  Shantilal, Prakash ^a   David, Joy ^a   Joseph, Thangam ^a  

^a ST JOHN'S NATIONAL ACADEMY OF HEALTH SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

FLUNARIZINE; PENTETRAZOLE; VALPROIC ACID;

ABSENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; BRAIN DEPTH STIMULATION; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; EPILEPTIC DISCHARGE; NONHUMAN; RAT; SEIZURE THRESHOLD; SPIKE WAVE; STIMULUS RESPONSE;

ANIMALS; ANTICONVULSANTS; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; ELECTROENCEPHALOGRAPHY; EPILEPSY, ABSENCE; FLUNARIZINE; MALE; PENTYLENETETRAZOLE; RATS; RATS, WISTAR; VALPROIC ACID;

ANIMALIA;

EID: 0033058598     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Berkovic S F, in Generalized absence seizures. in : The treatment of epilepsy : Principles and practice, edited by E Wyllie (Lea & Febiger, Philadelphia)1993,401.
2. Marescaux C, Micheletti G, Vergnes M, Depaulis A, Rumbach I & Warter J M, Epilepsia, 25 (1995) 1399.
3. Hosford D A, Wang Y, Liu C C & Snead O C, J Pharmacol Exp Ther, 274 (1995) 1399.
4. Joseph S, David J & Joseph T, Indian J Physiol Pharmacol, 42 (1998) 383.
5. Joseph S, David J & Joseph T, Indian J Exp Biol, 35 (1997) 933.
6. Joseph S, David J & Joseph T, Indian J Physiol Pharmacol, 42 (1998) 39
7. Rodger C & Pleuvry B J, Neuropharmacology, 32 (1993) 257.
8. Holmes B, Brogden R N, Heel R C, Speight T M & Avery G S, Drugs, 27 (1984) 6.
9. Desmedt L K C, Niemegeers C J E & Janssen P A J, Arzneimittel Forsch, 25 (1975) 1408.
10. McQueen J K & Woodbury D M, Epilepsia, 16 (1975) 295
11. Marescaux C & Vergnes M, Animal models of absence seizures and absence epilepsies, in Typical absences and related epileptic syndromes, edited by Duncan J S & Panayotopoulos (CPB, Churchill Livingstone Pvt.Ltd, New Delhi)1996.
12. Kamal J A, Nadig R S, Joseph T & David J, Indian J Exp Biol, 28 (1990) 605.
13. DeSarro G B, Nistico C & Meldrum B S, Neuropharmacology, 25 (1986) 695.
14. Binnie C D, in Antiepileptic drugs,' edited by R Levy, Mattson R, Meldrum B, Penry J K & Dreifuss F E, (Raven Press, New York) 1989, 971
15. Brown T R & Mirsky A F, in Antiepileptic drugs, edited by R Levy, Mattson R, Meldrum B, Penry J K & Dreifuss T E, (Raven Press, New York) 1989.
16. Becker A & Geksch G, Pharmacol Biochem Behav, 52 (1995) 705.
17. Van Luijtelaar E L J M, Ates N & Van der Staay F J, Pharmacol Biochem Behav, 48 (1994) 575.
18. McLean M J, Pol J Pharmacol, 39 (1987) 513
19. Pauwels PJ, Leysen J E & Janssen P A J, Life Sci, 48 (1990) 1881.
20. Nuglisch J, Rishke R & Kriegtestein- Pharmacology, 42 (1991) 333.