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Volumn 322, Issue 2-3, 1997, Pages 179-184

Anticonvulsant effects by combined treatment with a glycine, receptor antagonist and a polyamine site antagonist in amygdala-kindled rats

Author keywords

Complex partial seizure; Electrical kindling; Epilepsy; NMDA receptor

Indexed keywords

7 CHLORO 4 HYDROXY 3 (3 PHENOXYPHENYL) 2 QUINOLONE; GLYCINE RECEPTOR ANTAGONIST; IFENPRODIL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

EID: 0030986117     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)00084-8     Document Type: Article
Times cited : (30)

References (34)
  • 2
    • 0026630259 scopus 로고
    • Glycine antagonists: Regulation of the NMDA receptor-channel complex by strychnine-insensitive glycine site
    • Carter, A.J., 1992. Glycine antagonists: regulation of the NMDA receptor-channel complex by strychnine-insensitive glycine site. Drugs Future 17, 595-613.
    • (1992) Drugs Future , vol.17 , pp. 595-613
    • Carter, A.J.1
  • 3
    • 0028003653 scopus 로고
    • 2+ channels in rat and mouse cultured hippocampal pyramidal neurones: Comparison with N-methyl-D-aspartate receptor antagonist actions
    • 2+ channels in rat and mouse cultured hippocampal pyramidal neurones: comparison with N-methyl-D-aspartate receptor antagonist actions. Br. J. Pharmacol. 113, 499-507.
    • (1994) Br. J. Pharmacol. , vol.113 , pp. 499-507
    • Church, J.1    Fletcher, E.J.2    Baxter, K.3    MacDonald, J.F.4
  • 4
    • 0027817596 scopus 로고
    • Central effects of SL 82.0715, an antagonist of polyamine site of the NMDA receptor complex
    • Deren-Wesolek, A., Maj, J., 1993. Central effects of SL 82.0715, an antagonist of polyamine site of the NMDA receptor complex. Pol. J. Pharmacol. 45, 467-480.
    • (1993) Pol. J. Pharmacol. , vol.45 , pp. 467-480
    • Deren-Wesolek, A.1    Maj, J.2
  • 5
    • 0027390972 scopus 로고
    • Anticonvulsant properties of non-competitive antagonists of the N-methyl-D-aspartate receptor in genetically epilepsy-prone rats: Comparison with CPPene
    • De Sarro, G.B., De Sarro, A., 1992. Anticonvulsant properties of non-competitive antagonists of the N-methyl-D-aspartate receptor in genetically epilepsy-prone rats: comparison with CPPene. Neuropharmacology 32, 51-58.
    • (1992) Neuropharmacology , vol.32 , pp. 51-58
    • De Sarro, G.B.1    De Sarro, A.2
  • 6
    • 0027534142 scopus 로고
    • Antagonists of N-methyl-D-aspartate receptors block seizures induced by putrescine in the deep prepiriform cortex
    • De Sarro, G.B., Bagetta, G., Spagnolo, C., Nistico, G., 1992. Antagonists of N-methyl-D-aspartate receptors block seizures induced by putrescine in the deep prepiriform cortex. Neuropharmacology 32, 43-50.
    • (1992) Neuropharmacology , vol.32 , pp. 43-50
    • De Sarro, G.B.1    Bagetta, G.2    Spagnolo, C.3    Nistico, G.4
  • 7
    • 0029937775 scopus 로고    scopus 로고
    • Investigation of the involvement of the N-methyl-D-aspartate receptor macrocomplex in the development of spermine-induced CNS excitation in vivo
    • Doyle, K.M., Shaw, G.G., 1996. Investigation of the involvement of the N-methyl-D-aspartate receptor macrocomplex in the development of spermine-induced CNS excitation in vivo. Br. J. Pharmacol. 117, 1803-1808.
    • (1996) Br. J. Pharmacol. , vol.117 , pp. 1803-1808
    • Doyle, K.M.1    Shaw, G.G.2
  • 8
    • 0019854869 scopus 로고
    • The effect of interstimulation interval on the assessment and stability of kindled seizure threshold
    • Freeman, F.G., Jarvis, M.F., 1981. The effect of interstimulation interval on the assessment and stability of kindled seizure threshold. Brain Res. Bull. 7, 629-633.
    • (1981) Brain Res. Bull. , vol.7 , pp. 629-633
    • Freeman, F.G.1    Jarvis, M.F.2
  • 9
    • 0030047530 scopus 로고    scopus 로고
    • Modulation of channel function by polyamines
    • Johnson, T.D., 1996. Modulation of channel function by polyamines. Trends Pharmacol. Sci. 17, 22-27.
    • (1996) Trends Pharmacol. Sci. , vol.17 , pp. 22-27
    • Johnson, T.D.1
  • 10
    • 0023091647 scopus 로고
    • Glycine potentiates the NMDA response in cultured mouse brain neurones
    • Johnson, J.W., Ascher, P., 1987. Glycine potentiates the NMDA response in cultured mouse brain neurones. Nature 325, 529-531.
    • (1987) Nature , vol.325 , pp. 529-531
    • Johnson, J.W.1    Ascher, P.2
  • 11
    • 0027469106 scopus 로고
    • The glycine site of the NMDA receptor-five years on
    • Kemp, J.A., Leeson, P.D., 1993. The glycine site of the NMDA receptor-five years on. Trends Pharmacol. Sci. 14, 20-25.
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 20-25
    • Kemp, J.A.1    Leeson, P.D.2
  • 13
    • 0025251568 scopus 로고
    • The effect of interstimulation interval on the assessment of anticonvulsant drug potency in fully kindled rats
    • Löscher, W., Hönack, D., 1990. The effect of interstimulation interval on the assessment of anticonvulsant drug potency in fully kindled rats. Epilepsy Res. 7, 182-196.
    • (1990) Epilepsy Res. , vol.7 , pp. 182-196
    • Löscher, W.1    Hönack, D.2
  • 14
    • 0025963663 scopus 로고
    • Anticonvulsant and behavioural effects of two novel competitive N-methyl-D-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamazepine
    • Löscher, W., Hönack, D., 1991. Anticonvulsant and behavioural effects of two novel competitive N-methyl-D-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamazepine. J. Pharmacol. Exp. Ther. 256, 432-440.
    • (1991) J. Pharmacol. Exp. Ther. , vol.256 , pp. 432-440
    • Löscher, W.1    Hönack, D.2
  • 15
    • 0023897574 scopus 로고
    • Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations
    • Löscher, W., Schmidt, D., 1988. Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy Res. 2, 145-181.
    • (1988) Epilepsy Res. , vol.2 , pp. 145-181
    • Löscher, W.1    Schmidt, D.2
  • 16
    • 0028220347 scopus 로고
    • Strategies in antiepileptic drug development: Is rational drug design superior to random screening and structural variation?
    • Löscher, W., Schmidt, D., 1994. Strategies in antiepileptic drug development: is rational drug design superior to random screening and structural variation? Epilepsy Res. 17, 95-134.
    • (1994) Epilepsy Res. , vol.17 , pp. 95-134
    • Löscher, W.1    Schmidt, D.2
  • 17
    • 0027360461 scopus 로고
    • Low doses of NMDA receptor antagonists synergistically increase the anticonvulsant effect of the AMPA receptor antagonist NBQX in the kindling model of epilepsy
    • Löscher, W., Rundfeldt, C., Hönack, D., 1993. Low doses of NMDA receptor antagonists synergistically increase the anticonvulsant effect of the AMPA receptor antagonist NBQX in the kindling model of epilepsy. Eur. J. Neurosci. 5, 1545-1550.
    • (1993) Eur. J. Neurosci. , vol.5 , pp. 1545-1550
    • Löscher, W.1    Rundfeldt, C.2    Hönack, D.3
  • 18
    • 0028332352 scopus 로고
    • Anticonvulsant effects of the glycine/NMDA receptor ligands D-cycloserine and D-serine but not R-(+)-HA-966 in amygdala-kindled rats
    • Löscher, W., Wlaź, P., Rundfeldt, C., Baran, H., Hönack, D., 1994. Anticonvulsant effects of the glycine/NMDA receptor ligands D-cycloserine and D-serine but not R-(+)-HA-966 in amygdala-kindled rats. Br. J. Pharmacol. 112, 97-106.
    • (1994) Br. J. Pharmacol. , vol.112 , pp. 97-106
    • Löscher, W.1    Wlaź, P.2    Rundfeldt, C.3    Baran, H.4    Hönack, D.5
  • 19
    • 0028169485 scopus 로고
    • 3H]Dizolcipine association kinetics distinguish stimulatory and inhibitory polyamine sites of N-methyl-D-aspartate receptors
    • 3H]Dizolcipine association kinetics distinguish stimulatory and inhibitory polyamine sites of N-methyl-D-aspartate receptors. J. Neurochem. 63, 963-971.
    • (1994) J. Neurochem. , vol.63 , pp. 963-971
    • Marvizón, J.C.1    Baudry, M.2
  • 20
    • 0026593118 scopus 로고
    • N-Methyl-D-aspartate receptor antagonists and channel blockers have different effects upon a spinal seizure model in mice
    • McAllister, K.M., 1992. N-Methyl-D-aspartate receptor antagonists and channel blockers have different effects upon a spinal seizure model in mice. Eur. J. Pharmacol. 211, 105-108.
    • (1992) Eur. J. Pharmacol. , vol.211 , pp. 105-108
    • McAllister, K.M.1
  • 22
    • 0027017163 scopus 로고
    • NMDA receptor complex and kindling mechanisms
    • Engel Jr., J., Wasterlain, C., Cavalheiro, E.A., Heinemann, U., Avanzini, G. (Eds.), Elsevier, Amsterdam
    • Morimoto, K., Sato, M., 1992. NMDA receptor complex and kindling mechanisms. In: Engel Jr., J., Wasterlain, C., Cavalheiro, E.A., Heinemann, U., Avanzini, G. (Eds.), Molecular Neurobiology of Epilepsy. Elsevier, Amsterdam, pp. 297-305.
    • (1992) Molecular Neurobiology of Epilepsy , pp. 297-305
    • Morimoto, K.1    Sato, M.2
  • 24
    • 0015309163 scopus 로고
    • Modification of seizure activity by electrical stimulation. II. Motor seizure
    • Racine, R.J., 1972. Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 32, 281-294.
    • (1972) Electroencephalogr. Clin. Neurophysiol. , vol.32 , pp. 281-294
    • Racine, R.J.1
  • 25
    • 0025778964 scopus 로고
    • Polyamine and ifenprodil interactions with the NMDA receptor's glycine site
    • Ransom, R.W., 1992. Polyamine and ifenprodil interactions with the NMDA receptor's glycine site. Eur. J. Pharmacol. 208, 67-71.
    • (1992) Eur. J. Pharmacol. , vol.208 , pp. 67-71
    • Ransom, R.W.1
  • 26
    • 0023820777 scopus 로고
    • 3H]MK-SOl binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine, and polyamines
    • 3H]MK-SOl binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine, and polyamines. J. Neurochem. 51, 830-836.
    • (1988) J. Neurochem. , vol.51 , pp. 830-836
    • Ransom, R.W.1    Stec, N.L.2
  • 27
    • 0026671333 scopus 로고
    • The NMDA receptor, NMDA antagonists and epilepsy therapy
    • Rogawski, M.A., 1992. The NMDA receptor, NMDA antagonists and epilepsy therapy. Drugs 44, 279-292.
    • (1992) Drugs , vol.44 , pp. 279-292
    • Rogawski, M.A.1
  • 28
    • 0028038018 scopus 로고
    • Anticonvulsant activity of antagonists and partial agonists for the NMDA receptor-associated glycine site in the kindling model of epilepsy
    • Rundfeldt, C., Wlaź, P., Löscher, W., 1994. Anticonvulsant activity of antagonists and partial agonists for the NMDA receptor-associated glycine site in the kindling model of epilepsy. Brain Res. 653, 125-130.
    • (1994) Brain Res. , vol.653 , pp. 125-130
    • Rundfeldt, C.1    Wlaź, P.2    Löscher, W.3
  • 29
    • 0025193697 scopus 로고
    • 3H]ifenprodil, a novel NMDa antagonist, to a polyamine-sensitive site in the rat cerebral cortex
    • 3H]ifenprodil, a novel NMDA antagonist, to a polyamine-sensitive site in the rat cerebral cortex. Eur. J. Pharmacol. 176, 249-250.
    • (1990) Eur. J. Pharmacol. , vol.176 , pp. 249-250
    • Schoemaker, H.1    Allen, J.2    Langer, S.Z.3
  • 31
    • 0028220081 scopus 로고
    • Synergism between the NMDA receptor antagonistic effects of ifenprodil and the glycine antagonist, 7-chlorokynurenate, in vivo
    • Voltz, C., Page, D., Carter, C., 1994. Synergism between the NMDA receptor antagonistic effects of ifenprodil and the glycine antagonist, 7-chlorokynurenate, in vivo. Eur. J. Pharmacol. 255, 197-202.
    • (1994) Eur. J. Pharmacol. , vol.255 , pp. 197-202
    • Voltz, C.1    Page, D.2    Carter, C.3
  • 32
    • 0027525324 scopus 로고
    • Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: Selectivity and mechanisms at recombinant heteromeric receptors
    • Williams, K., 1993. Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors. Mol. Pharmacol. 44, 851-859.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 851-859
    • Williams, K.1
  • 33
    • 0028099671 scopus 로고
    • Low doses of the glycine/NMDA receptor antagonist R-(+)-HA-966 but not D-cycloserine induce paroxysmal activity in limbic brain regions of kindled rats
    • Wlaź, P., Ebert, U., Löscher, W., 1994. Low doses of the glycine/NMDA receptor antagonist R-(+)-HA-966 but not D-cycloserine induce paroxysmal activity in limbic brain regions of kindled rats. Eur. J. Neurosci. 6, 1710-1719.
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 1710-1719
    • Wlaź, P.1    Ebert, U.2    Löscher, W.3
  • 34
    • 0028181144 scopus 로고
    • The NMDA antagonist procyclidine, but not ifenprodil, enhances the protective efficacy of common antiepileptics against maximal electroshock-induced seizures in mice
    • Zarnowski, T., Kleinrok, Z., Turski, W.A., Czuczwar, S.J., 1994. The NMDA antagonist procyclidine, but not ifenprodil, enhances the protective efficacy of common antiepileptics against maximal electroshock-induced seizures in mice. J. Neural Transm. Gen. Sect. 97, 1-12.
    • (1994) J. Neural Transm. Gen. Sect. , vol.97 , pp. 1-12
    • Zarnowski, T.1    Kleinrok, Z.2    Turski, W.A.3    Czuczwar, S.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.