메뉴 건너뛰기




Volumn 232, Issue 3, 2007, Pages 370-384

Parallel signaling pathways in endothelin-1-induced proliferation of U373MG astrocytoma cells

Author keywords

Astrocyte; Cell proliferation; Endothelin 1; Signal transduction

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CALCIUM; CHELERYTHRINE; ENDOTHELIN 1; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; RAS PROTEIN;

EID: 33847407020     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (80)
  • 1
    • 0036278328 scopus 로고    scopus 로고
    • Endothelin: Is it a contributor to glaucoma pathophysiology?
    • Yorio T, Krishnamoorthy R, Prasanna G. Endothelin: is it a contributor to glaucoma pathophysiology? J Glaucoma 11:259-270, 2002.
    • (2002) J Glaucoma , vol.11 , pp. 259-270
    • Yorio, T.1    Krishnamoorthy, R.2    Prasanna, G.3
  • 2
    • 2442480730 scopus 로고    scopus 로고
    • Hypoxia augments TNF-[alpha]-mediated endothelin-1 release and cell proliferation in human optic nerve head astrocytes
    • Desai D, He S, Yorio T, Krishnamoorthy RR, Prasanna G. Hypoxia augments TNF-[alpha]-mediated endothelin-1 release and cell proliferation in human optic nerve head astrocytes. Biochem Biophys Res Commun 318:642-648, 2004.
    • (2004) Biochem Biophys Res Commun , vol.318 , pp. 642-648
    • Desai, D.1    He, S.2    Yorio, T.3    Krishnamoorthy, R.R.4    Prasanna, G.5
  • 3
    • 0035208066 scopus 로고    scopus 로고
    • Cellular distribution of endothelin-1 mRNA in human brain by in situ RT-PCR
    • Naidoo V, Mahabeer R, Raidoo DM. Cellular distribution of endothelin-1 mRNA in human brain by in situ RT-PCR. Metab Brain Dis 16:207-218, 2001.
    • (2001) Metab Brain Dis , vol.16 , pp. 207-218
    • Naidoo, V.1    Mahabeer, R.2    Raidoo, D.M.3
  • 4
    • 0036672425 scopus 로고    scopus 로고
    • Three vasoactive peptides, endothelin-1, adrenomedullin and urotensin-II, in human tumour cell lines of different origin: Expression and effects on proliferation
    • Takahashi K, Totsune K, Kitamuro T, Sone M, Murakami O, Shibahara S. Three vasoactive peptides, endothelin-1, adrenomedullin and urotensin-II, in human tumour cell lines of different origin: expression and effects on proliferation. Clin Sci 103:35S-38S, 2002.
    • (2002) Clin Sci , vol.103
    • Takahashi, K.1    Totsune, K.2    Kitamuro, T.3    Sone, M.4    Murakami, O.5    Shibahara, S.6
  • 8
    • 0034195203 scopus 로고    scopus 로고
    • Cytosolic phospholipase A2 and the distinct transcriptional programs of astrocytoma cells
    • Hernandez M, Nieto ML, Sanchez Crespo M. Cytosolic phospholipase A2 and the distinct transcriptional programs of astrocytoma cells. Trends Neurosci 23:259-264, 2000.
    • (2000) Trends Neurosci , vol.23 , pp. 259-264
    • Hernandez, M.1    Nieto, M.L.2    Sanchez Crespo, M.3
  • 9
    • 0033997806 scopus 로고    scopus 로고
    • The optic nerve head in glaucoma: Role of astrocytes in tissue remodeling
    • Hernandez MR. The optic nerve head in glaucoma: role of astrocytes in tissue remodeling. Prog Retin Eye Res 19:297-321, 2000.
    • (2000) Prog Retin Eye Res , vol.19 , pp. 297-321
    • Hernandez, M.R.1
  • 10
    • 0037467569 scopus 로고    scopus 로고
    • Endothelin-1: A multifunctional molecule in cancer
    • Grant K, Loizidou M, Taylor I. Endothelin-1: a multifunctional molecule in cancer. Br J Cancer 88:163-166, 2003.
    • (2003) Br J Cancer , vol.88 , pp. 163-166
    • Grant, K.1    Loizidou, M.2    Taylor, I.3
  • 11
    • 0037794389 scopus 로고    scopus 로고
    • The brain endothelin system as potential target for brain-related pathologies
    • Schinelli S. The brain endothelin system as potential target for brain-related pathologies. Curr Drug Target CNS Neurol Disord 1:543-553, 2002.
    • (2002) Curr Drug Target CNS Neurol Disord , vol.1 , pp. 543-553
    • Schinelli, S.1
  • 12
    • 0035195281 scopus 로고    scopus 로고
    • ET-1 stimulates pulmonary arterial smooth muscle cell proliferation via induction of reactive oxygen species
    • Wedgwood S, Dettman RW, Black SM. ET-1 stimulates pulmonary arterial smooth muscle cell proliferation via induction of reactive oxygen species. Am J Physiol Lung Cell Mol Physiol 281:L1058-L1067, 2001.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.281
    • Wedgwood, S.1    Dettman, R.W.2    Black, S.M.3
  • 14
    • 0029670629 scopus 로고    scopus 로고
    • Coupling of ETB endothelin receptor to mitogen-activated protein kinase stimulation and DNA synthesis in primary cultures of rat astrocytes
    • Lazarini F, Strosberg AD, Couraud PO, Cazaubon SM. Coupling of ETB endothelin receptor to mitogen-activated protein kinase stimulation and DNA synthesis in primary cultures of rat astrocytes. J Neurochem 66:459-465, 1996.
    • (1996) J Neurochem , vol.66 , pp. 459-465
    • Lazarini, F.1    Strosberg, A.D.2    Couraud, P.O.3    Cazaubon, S.M.4
  • 15
    • 0028028402 scopus 로고
    • Endothelins stimulate mitogen activated protein kinase cascade through either ETA or ETB
    • Wang Y, Rose P, Webb M, Dunn M. Endothelins stimulate mitogen activated protein kinase cascade through either ETA or ETB. Am J Physiol 267:C1130-C1135, 1994.
    • (1994) Am J Physiol , vol.267
    • Wang, Y.1    Rose, P.2    Webb, M.3    Dunn, M.4
  • 17
    • 0033966163 scopus 로고    scopus 로고
    • Stimulation of endothelin B receptor modulates the inflammatory activation of rat astrocytes
    • Morga E, Faber C, Heuschling P. Stimulation of endothelin B receptor modulates the inflammatory activation of rat astrocytes. J Neurochem 74:603-612, 2000.
    • (2000) J Neurochem , vol.74 , pp. 603-612
    • Morga, E.1    Faber, C.2    Heuschling, P.3
  • 18
    • 0037440416 scopus 로고    scopus 로고
    • Endothelin B receptors are expressed by astrocytes and regulate astrocyte hypertrophy in the normal and injured CNS
    • Rogers S, Peters C, Pomonis J, Hagiwara H, Ghilardi J, Mantyh P. Endothelin B receptors are expressed by astrocytes and regulate astrocyte hypertrophy in the normal and injured CNS. Glia 41:180-190, 2003.
    • (2003) Glia , vol.41 , pp. 180-190
    • Rogers, S.1    Peters, C.2    Pomonis, J.3    Hagiwara, H.4    Ghilardi, J.5    Mantyh, P.6
  • 20
    • 0036607064 scopus 로고    scopus 로고
    • Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation
    • Stork PJS, Schmitt JM. Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation. Trends Cell Biol 12:258-266, 2002.
    • (2002) Trends Cell Biol , vol.12 , pp. 258-266
    • Stork, P.J.S.1    Schmitt, J.M.2
  • 21
    • 0037962080 scopus 로고    scopus 로고
    • An overview of endothelin signaling in the cardiac myocyte
    • Sugden P. An overview of endothelin signaling in the cardiac myocyte. J Mol Cell Cardiol 35:871-886, 2003.
    • (2003) J Mol Cell Cardiol , vol.35 , pp. 871-886
    • Sugden, P.1
  • 22
    • 0034667593 scopus 로고    scopus 로고
    • Meaningful relationships: The regulation of the Ras/Raf/MEK/ERK pathway by protein interactions
    • Kolch W. Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. Biochem J 351:289-305, 2000.
    • (2000) Biochem J , vol.351 , pp. 289-305
    • Kolch, W.1
  • 23
    • 0036082913 scopus 로고    scopus 로고
    • ET-1 stimulates ERK signaling pathway through sequential activation of PKC and Src in rat myometrial cells
    • Robin P, Boulven I, Desmyter C, Harbon S, Leiber D. ET-1 stimulates ERK signaling pathway through sequential activation of PKC and Src in rat myometrial cells. Am J Physiol Cell Physiol 283:C251-C260, 2002.
    • (2002) Am J Physiol Cell Physiol , vol.283
    • Robin, P.1    Boulven, I.2    Desmyter, C.3    Harbon, S.4    Leiber, D.5
  • 24
    • 0034935398 scopus 로고    scopus 로고
    • Endothelins: Vasoactive modulators of renal function in health and disease
    • Naicker S, Bhoola KD. Endothelins: vasoactive modulators of renal function in health and disease. Pharmacol Ther 90:61-88, 2001.
    • (2001) Pharmacol Ther , vol.90 , pp. 61-88
    • Naicker, S.1    Bhoola, K.D.2
  • 25
    • 2542485410 scopus 로고    scopus 로고
    • Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/PI3 kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts
    • Shi-Wen X, Chen Y, Denton C, Eastwood M, Renzoni E, Bou-Gharios G, Pearson J, Dashwood M, DuBois R, Black C, Leask A, Abraham D. Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/PI3 kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts. Mol Biol Cell 15:2707-2719, 2004.
    • (2004) Mol Biol Cell , vol.15 , pp. 2707-2719
    • Shi-Wen, X.1    Chen, Y.2    Denton, C.3    Eastwood, M.4    Renzoni, E.5    Bou-Gharios, G.6    Pearson, J.7    Dashwood, M.8    DuBois, R.9    Black, C.10    Leask, A.11    Abraham, D.12
  • 26
    • 0035890485 scopus 로고    scopus 로고
    • Src-family tyrosine kinases, phosphoinositide 3-kinase and Gab1 regulate extracellular signal-regulated kinase 1 activation induced by the type A endothelin-1 G-protein-coupled receptor
    • Bisotto S, Fixman ED. Src-family tyrosine kinases, phosphoinositide 3-kinase and Gab1 regulate extracellular signal-regulated kinase 1 activation induced by the type A endothelin-1 G-protein-coupled receptor. Biochem J 360:77-85, 2001.
    • (2001) Biochem J , vol.360 , pp. 77-85
    • Bisotto, S.1    Fixman, E.D.2
  • 28
    • 0028589299 scopus 로고
    • Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts
    • Clerk A, Bogoyevitch M, Anderson M, Sugden P. Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts. J Biol Chem 269:32848-32857, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 32848-32857
    • Clerk, A.1    Bogoyevitch, M.2    Anderson, M.3    Sugden, P.4
  • 29
    • 2142827895 scopus 로고    scopus 로고
    • Contribution of PKC-dependent and -independent processes in temporal ERK regulation by ET-1, PDGF, and EGF in rat myometrial cells
    • Robin P, Boulven I, Bole-Feysot C, Tanfin Z, Leiber D. Contribution of PKC-dependent and -independent processes in temporal ERK regulation by ET-1, PDGF, and EGF in rat myometrial cells. Am J Physiol Cell Physiol 286:C798-C806, 2004.
    • (2004) Am J Physiol Cell Physiol , vol.286
    • Robin, P.1    Boulven, I.2    Bole-Feysot, C.3    Tanfin, Z.4    Leiber, D.5
  • 31
    • 0036800347 scopus 로고    scopus 로고
    • Role of PKC and MAPK in cytosolic PLA2 phosphorylation and arachadonic acid release in primary murine astrocytes
    • Xu J, Weng Y-I, Simoni A, Krugh BW, Liao Z, Weisman GA, Sun GY. Role of PKC and MAPK in cytosolic PLA2 phosphorylation and arachadonic acid release in primary murine astrocytes. J Neurochem 83:259-270, 2002.
    • (2002) J Neurochem , vol.83 , pp. 259-270
    • Xu, J.1    Weng, Y.-I.2    Simoni, A.3    Krugh, B.W.4    Liao, Z.5    Weisman, G.A.6    Sun, G.Y.7
  • 32
    • 0030847392 scopus 로고    scopus 로고
    • The ATP-depleting reagent iodoacetamide induces the degradation of protein kinase C alpha (PKC alpha) in LLC-PK1 pig kidney cells
    • Dibas A, Wood J, Mia A, Yorio T. The ATP-depleting reagent iodoacetamide induces the degradation of protein kinase C alpha (PKC alpha) in LLC-PK1 pig kidney cells. Life Sci 61:1697-1704, 1997.
    • (1997) Life Sci , vol.61 , pp. 1697-1704
    • Dibas, A.1    Wood, J.2    Mia, A.3    Yorio, T.4
  • 34
    • 0034031457 scopus 로고    scopus 로고
    • Cholinergic and adrenergic modulation of the Ca2+ response to endothelin-1 in human ciliary muscle cells
    • Prasanna G, Dibas AI, Yorio T. Cholinergic and adrenergic modulation of the Ca2+ response to endothelin-1 in human ciliary muscle cells. Invest Ophthalmol Vis Sci 41:1142-1148, 2000.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 1142-1148
    • Prasanna, G.1    Dibas, A.I.2    Yorio, T.3
  • 35
    • 0021895138 scopus 로고
    • A new generation of Ca2+ indicators with greatly improved fluorescence properties
    • Grynkiewicz G, Poenie M, Tsien R. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450, 1985.
    • (1985) J Biol Chem , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.3
  • 36
    • 0029056170 scopus 로고
    • Endothelin receptor in human astrocytoma U373MG cells: Binding, dissociation, receptor internalization
    • Wu-Wong J, Chiou W, Magnuson S, Opgenorth T. Endothelin receptor in human astrocytoma U373MG cells: binding, dissociation, receptor internalization. J Pharmacol Exp Ther 274:499-507, 1995.
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 499-507
    • Wu-Wong, J.1    Chiou, W.2    Magnuson, S.3    Opgenorth, T.4
  • 37
    • 0036789949 scopus 로고    scopus 로고
    • Ras and relatives - job sharing and networking keep an old family together
    • Ehrhardt A, Ehrhardt GRA, Guo X, Schrader JW. Ras and relatives - job sharing and networking keep an old family together. Exp Hematol 30:1089-1106, 2002.
    • (2002) Exp Hematol , vol.30 , pp. 1089-1106
    • Ehrhardt, A.1    Ehrhardt, G.R.A.2    Guo, X.3    Schrader, J.W.4
  • 38
    • 0037400510 scopus 로고    scopus 로고
    • Mechanisms of regulating the Raf kinase family
    • Chong H, Vikis HG, Guan K-L. Mechanisms of regulating the Raf kinase family. Cell Signal 15:463-469, 2003.
    • (2003) Cell Signal , vol.15 , pp. 463-469
    • Chong, H.1    Vikis, H.G.2    Guan, K.-L.3
  • 39
    • 0032508517 scopus 로고    scopus 로고
    • Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase
    • Yan J, Roy S, Apolloni A, Lane A, Hancock JF. Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase. J Biol Chem 273:24052-24056, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 24052-24056
    • Yan, J.1    Roy, S.2    Apolloni, A.3    Lane, A.4    Hancock, J.F.5
  • 40
    • 4544355312 scopus 로고    scopus 로고
    • H-Ras and PI3K cooperate to induce FucT-VII expression in Jurkat T cells
    • Zisoulis DG, Kansas GS. H-Ras and PI3K cooperate to induce FucT-VII expression in Jurkat T cells. J Biol Chem 279:39495-39504, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 39495-39504
    • Zisoulis, D.G.1    Kansas, G.S.2
  • 41
    • 0035890158 scopus 로고    scopus 로고
    • Stimulation of endothelin B receptors in astrocytes induces cAMP response element-binding protein phosphorylation and c-fos expression via multiple mitogen-activated protein kinase signaling pathways
    • Schinelli S, Zanassi P, Paolillo M, Wang H, Feliciello A, Gallo V. Stimulation of endothelin B receptors in astrocytes induces cAMP response element-binding protein phosphorylation and c-fos expression via multiple mitogen-activated protein kinase signaling pathways. J Neurosci 21:8842-8853, 2001.
    • (2001) J Neurosci , vol.21 , pp. 8842-8853
    • Schinelli, S.1    Zanassi, P.2    Paolillo, M.3    Wang, H.4    Feliciello, A.5    Gallo, V.6
  • 42
    • 0028973293 scopus 로고
    • Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes
    • Lerner EC, Qian Y, Blaskovich MA, Fossum RD, Vogt A, Sun J, Cox AD, Der CJ, Hamilton AD, Sebti SM. Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes. J Biol Chem 270:26802-26806, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 26802-26806
    • Lerner, E.C.1    Qian, Y.2    Blaskovich, M.A.3    Fossum, R.D.4    Vogt, A.5    Sun, J.6    Cox, A.D.7    Der, C.J.8    Hamilton, A.D.9    Sebti, S.M.10
  • 44
    • 0042305250 scopus 로고    scopus 로고
    • Focal adhesion kinase is required for endothelin-induced cell cycle progression of cultured astrocytes
    • Koyama Y, Yoshioka Y, Matsuda T, Baba A. Focal adhesion kinase is required for endothelin-induced cell cycle progression of cultured astrocytes. Glia 43:185-189, 2003.
    • (2003) Glia , vol.43 , pp. 185-189
    • Koyama, Y.1    Yoshioka, Y.2    Matsuda, T.3    Baba, A.4
  • 45
    • 0034722049 scopus 로고    scopus 로고
    • Endothelins increase tyrosine phosphorylation of astrocytic focal adhesion kinase and paxillin accompanied by their association with cytoskeletal components
    • Koyama Y, Yoshioka Y, Hashimoto H, Matsuda T, Baba A. Endothelins increase tyrosine phosphorylation of astrocytic focal adhesion kinase and paxillin accompanied by their association with cytoskeletal components. Neuroscience 101:219-227, 2000.
    • (2000) Neuroscience , vol.101 , pp. 219-227
    • Koyama, Y.1    Yoshioka, Y.2    Hashimoto, H.3    Matsuda, T.4    Baba, A.5
  • 46
    • 0037303578 scopus 로고    scopus 로고
    • Endothelin-1 activates mesangial cell ERK1/2 via EGF-receptor transactivation and caveolin-1 interaction
    • Hua H, Munk S, Whiteside CI. Endothelin-1 activates mesangial cell ERK1/2 via EGF-receptor transactivation and caveolin-1 interaction. Am J Physiol Renal Physiol 284:F303-F312, 2003.
    • (2003) Am J Physiol Renal Physiol , vol.284
    • Hua, H.1    Munk, S.2    Whiteside, C.I.3
  • 47
    • 2442716423 scopus 로고    scopus 로고
    • Involvement of epidermal growth factor receptor-protein tyrosine kinase transactivation in endothelin-1-induced vascular contraction
    • Kawanabe Y, Masaki T, Hashimoto N. Involvement of epidermal growth factor receptor-protein tyrosine kinase transactivation in endothelin-1-induced vascular contraction. J Neurosurg 100:1066-1071, 2004.
    • (2004) J Neurosurg , vol.100 , pp. 1066-1071
    • Kawanabe, Y.1    Masaki, T.2    Hashimoto, N.3
  • 48
    • 0141428768 scopus 로고    scopus 로고
    • Involvement of extracellular Ca2+ influx and epidermal growth factor receptor tyrosine kinase transactivation in endothelin-1-induced arachidonic acid release
    • Kawanabe Y, Nozaki K, Hashimoto N, Masaki T. Involvement of extracellular Ca2+ influx and epidermal growth factor receptor tyrosine kinase transactivation in endothelin-1-induced arachidonic acid release. Br J Pharmacol 139:1516-1522, 2003.
    • (2003) Br J Pharmacol , vol.139 , pp. 1516-1522
    • Kawanabe, Y.1    Nozaki, K.2    Hashimoto, N.3    Masaki, T.4
  • 49
    • 0034721611 scopus 로고    scopus 로고
    • Intracellular signaling mechanisms leading to synergistic effects of endothelin-1 and stem cell factor on proliferation of cultured human melanocytes. Cross-talk via trans-activation of the tyrosine kinase c-kit receptor
    • Imokawa G, Kobayasi T, Miyagishi M. Intracellular signaling mechanisms leading to synergistic effects of endothelin-1 and stem cell factor on proliferation of cultured human melanocytes. Cross-talk via trans-activation of the tyrosine kinase c-kit receptor. J Biol Chem 275:33321-33328, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 33321-33328
    • Imokawa, G.1    Kobayasi, T.2    Miyagishi, M.3
  • 50
    • 0034665584 scopus 로고    scopus 로고
    • Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells
    • Vacca F, Bagnato A, Catt KJ, Tecce R. Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells. Cancer Res 60:5310-5317, 2000.
    • (2000) Cancer Res , vol.60 , pp. 5310-5317
    • Vacca, F.1    Bagnato, A.2    Catt, K.J.3    Tecce, R.4
  • 51
    • 0042750799 scopus 로고    scopus 로고
    • Akt and PI 3-kinase signaling in cardiomyocyte hypertrophy and survival
    • Matsui T, Nagoshi T, Rosenzweig A. Akt and PI 3-kinase signaling in cardiomyocyte hypertrophy and survival. Cell Cycle 2:220-223, 2003.
    • (2003) Cell Cycle , vol.2 , pp. 220-223
    • Matsui, T.1    Nagoshi, T.2    Rosenzweig, A.3
  • 52
    • 0037352170 scopus 로고    scopus 로고
    • Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: A target for cancer chemotherapy
    • Chang F, Lee J, Navolanic P, Steelman L, Shelton J, Blalock W, Franklin R, McCubrey J. Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. Leukemia 17:590-603, 2003.
    • (2003) Leukemia , vol.17 , pp. 590-603
    • Chang, F.1    Lee, J.2    Navolanic, P.3    Steelman, L.4    Shelton, J.5    Blalock, W.6    Franklin, R.7    McCubrey, J.8
  • 53
    • 0031037296 scopus 로고    scopus 로고
    • Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma
    • Lopez-Ilasaca M, Crespo P, Pellici PG, Gutkind JS, Wetzker R. Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma. Science 275:394-397, 1997.
    • (1997) Science , vol.275 , pp. 394-397
    • Lopez-Ilasaca, M.1    Crespo, P.2    Pellici, P.G.3    Gutkind, J.S.4    Wetzker, R.5
  • 54
    • 0347379916 scopus 로고    scopus 로고
    • Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein βγ subunit signaling to protein kinase B/Akt
    • Liu S, Premont RT, Kontos CD, Huang J, Rockey DC. Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein βγ subunit signaling to protein kinase B/Akt. J Biol Chem 278:49929-49935, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 49929-49935
    • Liu, S.1    Premont, R.T.2    Kontos, C.D.3    Huang, J.4    Rockey, D.C.5
  • 55
    • 0141953294 scopus 로고    scopus 로고
    • Activation of stimulatory heterotrimeric G proteins increases glutathione and protects neuronal cells against oxidative stress
    • Lewerenz J, Letz J, Methner A. Activation of stimulatory heterotrimeric G proteins increases glutathione and protects neuronal cells against oxidative stress. J Neurochem 87:522-531, 2003.
    • (2003) J Neurochem , vol.87 , pp. 522-531
    • Lewerenz, J.1    Letz, J.2    Methner, A.3
  • 56
    • 0042531667 scopus 로고    scopus 로고
    • Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK
    • Miyamoto Y, Yamauchi J, Itoh H. Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK. J Biol Chem 278:29890-29900, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 29890-29900
    • Miyamoto, Y.1    Yamauchi, J.2    Itoh, H.3
  • 57
    • 0032230175 scopus 로고    scopus 로고
    • Endothelin-1 is a potent survival factor for c-Myc-dependent apoptosis
    • Shichiri M, Sedivy JM, Marumo F, Hirata Y. Endothelin-1 is a potent survival factor for c-Myc-dependent apoptosis. Mol Endocrinol 12:172-180, 1998.
    • (1998) Mol Endocrinol , vol.12 , pp. 172-180
    • Shichiri, M.1    Sedivy, J.M.2    Marumo, F.3    Hirata, Y.4
  • 58
    • 0037302999 scopus 로고    scopus 로고
    • High glucose-induced, endothelin-dependent fibronectin synthesis is mediated via NF-kappa B and AP-1
    • Chen S, Mukherjee S, Chakraborty C, Chakrabarti S. High glucose-induced, endothelin-dependent fibronectin synthesis is mediated via NF-kappa B and AP-1. Am J Physiol Cell Physiol 284:C263-C272, 2003.
    • (2003) Am J Physiol Cell Physiol , vol.284
    • Chen, S.1    Mukherjee, S.2    Chakraborty, C.3    Chakrabarti, S.4
  • 59
    • 1942503372 scopus 로고    scopus 로고
    • Intracellular signaling pathways for norepinephrine- and endothelin-1-mediated regulation of myocardial cell apoptosis
    • Iwai-Kanai E, Hasegawa K. Intracellular signaling pathways for norepinephrine- and endothelin-1-mediated regulation of myocardial cell apoptosis. Mol Cell Biochem 259:163-168, 2004.
    • (2004) Mol Cell Biochem , vol.259 , pp. 163-168
    • Iwai-Kanai, E.1    Hasegawa, K.2
  • 60
    • 6344282286 scopus 로고    scopus 로고
    • Role of protein kinase Cd in endothelin-induced Type I collagen expression in cardiac myofibroblasts isolated from the site of myocardial infarction
    • Chintalgattu V, Katwa LC. Role of protein kinase Cd in endothelin-induced Type I collagen expression in cardiac myofibroblasts isolated from the site of myocardial infarction. J Pharmacol Exp Ther 311:691-699, 2004.
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 691-699
    • Chintalgattu, V.1    Katwa, L.C.2
  • 61
    • 24644495234 scopus 로고    scopus 로고
    • Endothelin signalling in the cardiac myocyte and its pathophysiological relevance
    • Sugden PH, Clerk A. Endothelin signalling in the cardiac myocyte and its pathophysiological relevance. Curr Vasc Pharmacol 3:343-351, 2005.
    • (2005) Curr Vasc Pharmacol , vol.3 , pp. 343-351
    • Sugden, P.H.1    Clerk, A.2
  • 62
    • 0035489474 scopus 로고    scopus 로고
    • High glucose-enhanced mesangial cell extracellular signal-regulated protein kinase activation and α1(IV) collagen expression in response to endothelin-1: Role of specific protein kinase C isozymes
    • Hua H, Goldberg HJ, Fantus IG, Whiteside CI. High glucose-enhanced mesangial cell extracellular signal-regulated protein kinase activation and α1(IV) collagen expression in response to endothelin-1: role of specific protein kinase C isozymes. Diabetes 50:2376-2383, 2001.
    • (2001) Diabetes , vol.50 , pp. 2376-2383
    • Hua, H.1    Goldberg, H.J.2    Fantus, I.G.3    Whiteside, C.I.4
  • 65
    • 0035952644 scopus 로고    scopus 로고
    • G-proteins in growth and apoptosis: Lessons from the heart
    • Adamsa JW, Brown JH. G-proteins in growth and apoptosis: lessons from the heart. Oncegene 20:1626-1634, 2001.
    • (2001) Oncegene , vol.20 , pp. 1626-1634
    • Adamsa, J.W.1    Brown, J.H.2
  • 66
    • 33745948728 scopus 로고    scopus 로고
    • Expression of endothelins and their receptors in glioblastoma cell lines
    • Paolillo M, Barbieri A, Zanassi P, Schinelli S. Expression of endothelins and their receptors in glioblastoma cell lines. J Neurooncol 79:1-7, 2006.
    • (2006) J Neurooncol , vol.79 , pp. 1-7
    • Paolillo, M.1    Barbieri, A.2    Zanassi, P.3    Schinelli, S.4
  • 67
  • 68
    • 0036024236 scopus 로고    scopus 로고
    • Characterization of G proteins involved in activation of nonselective cation channels by endothelin B receptor
    • Kawanabe Y, Hashimoto N, Masaki T. Characterization of G proteins involved in activation of nonselective cation channels by endothelin B receptor. Br J Pharmacol 136:1015-1022, 2002.
    • (2002) Br J Pharmacol , vol.136 , pp. 1015-1022
    • Kawanabe, Y.1    Hashimoto, N.2    Masaki, T.3
  • 69
    • 19344365072 scopus 로고    scopus 로고
    • Involvement of extracellular Ca2+ influx through voltage-independent Ca2+ channels in endothelin-1 function
    • Kawanabe Y, Nauli SM. Involvement of extracellular Ca2+ influx through voltage-independent Ca2+ channels in endothelin-1 function. Cell Signal 17:911-916, 2005.
    • (2005) Cell Signal , vol.17 , pp. 911-916
    • Kawanabe, Y.1    Nauli, S.M.2
  • 71
    • 0035902998 scopus 로고    scopus 로고
    • B103 neuroblastoma cells predominantly express endothelin ETB receptor; effects of extracellular Ca2+ influx on endothelin-1-induced mitogenesis
    • Kawanabe Y, Hashimoto N, Masaki T. B103 neuroblastoma cells predominantly express endothelin ETB receptor; effects of extracellular Ca2+ influx on endothelin-1-induced mitogenesis. Eur J Pharmacol 425:173-179, 2001.
    • (2001) Eur J Pharmacol , vol.425 , pp. 173-179
    • Kawanabe, Y.1    Hashimoto, N.2    Masaki, T.3
  • 72
    • 33645105623 scopus 로고    scopus 로고
    • Differential negative coupling of type 3 metabotropic glutamate receptor to cyclic GMP levels in neurons and astrocytes
    • Wroblewska B, Wegorzewska IN, Bzdega T, Olszewski RT, Neale JH. Differential negative coupling of type 3 metabotropic glutamate receptor to cyclic GMP levels in neurons and astrocytes. J Neurochem 96:1071-1077, 2006.
    • (2006) J Neurochem , vol.96 , pp. 1071-1077
    • Wroblewska, B.1    Wegorzewska, I.N.2    Bzdega, T.3    Olszewski, R.T.4    Neale, J.H.5
  • 73
    • 33747593745 scopus 로고    scopus 로고
    • Regional differences in the coupling of 5-hydroxytryptamine-1A receptors to G proteins in the rat brain
    • la Cour CM, El Mestikawy S, Hanoun N, Hamon M, Lanfumey L. Regional differences in the coupling of 5-hydroxytryptamine-1A receptors to G proteins in the rat brain. Mol Pharmacol 70:1013-1021, 2006.
    • (2006) Mol Pharmacol , vol.70 , pp. 1013-1021
    • la Cour, C.M.1    El Mestikawy, S.2    Hanoun, N.3    Hamon, M.4    Lanfumey, L.5
  • 75
    • 0034668121 scopus 로고    scopus 로고
    • Protein kinase C ζ plays a central role in activation of the p42/44 mitogen-activated protein kinase by endotoxin in alveolar macrophages
    • Monick MM, Carter AB, Flaherty DM, Peterson MW, Hunninghake GW. Protein kinase C ζ plays a central role in activation of the p42/44 mitogen-activated protein kinase by endotoxin in alveolar macrophages. J Immunol 165:4632-4639, 2000.
    • (2000) J Immunol , vol.165 , pp. 4632-4639
    • Monick, M.M.1    Carter, A.B.2    Flaherty, D.M.3    Peterson, M.W.4    Hunninghake, G.W.5
  • 77
    • 0027955166 scopus 로고
    • Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy
    • Bogoyevitch M, Glennon P, Andersson M, Clerk A, Lazou A, Marshall C, Parker P, Sugden P. Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy. J Biol Chem 269:1110-1119, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 1110-1119
    • Bogoyevitch, M.1    Glennon, P.2    Andersson, M.3    Clerk, A.4    Lazou, A.5    Marshall, C.6    Parker, P.7    Sugden, P.8
  • 78
    • 0344010025 scopus 로고    scopus 로고
    • Involvement of ras activation in toxic hair cell damage of the mammalian cochlea
    • Battaglia A, Pak K, Brors D, Bodmer D, Frangos JA, Ryan AF. Involvement of ras activation in toxic hair cell damage of the mammalian cochlea. Neuroscience 122:1025-1035, 2003.
    • (2003) Neuroscience , vol.122 , pp. 1025-1035
    • Battaglia, A.1    Pak, K.2    Brors, D.3    Bodmer, D.4    Frangos, J.A.5    Ryan, A.F.6
  • 79
    • 0037328558 scopus 로고    scopus 로고
    • The farnesyl transferase inhibitor, FTI-277, inhibits growth and induces apoptosis in drug-resistant myeloma tumor cells
    • Bolick S, Landowski T, Boulware D, Oshiro M, Ohkanda J, Hamilton A, Sebti S, Dalton W. The farnesyl transferase inhibitor, FTI-277, inhibits growth and induces apoptosis in drug-resistant myeloma tumor cells. Leukemia 17:451-457, 2003.
    • (2003) Leukemia , vol.17 , pp. 451-457
    • Bolick, S.1    Landowski, T.2    Boulware, D.3    Oshiro, M.4    Ohkanda, J.5    Hamilton, A.6    Sebti, S.7    Dalton, W.8
  • 80
    • 0033835421 scopus 로고    scopus 로고
    • The importance of being K-Ras
    • Ellis CA, Clark G. The importance of being K-Ras. Cell Signal 12:425-434, 2000.
    • (2000) Cell Signal , vol.12 , pp. 425-434
    • Ellis, C.A.1    Clark, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.