Stimulation of endothelin B receptors in astrocytes induces cAMP response element-binding protein phosphorylation and c-fos expression via multiple mitogen-activated protein kinase signaling pathways

Journal of Neuroscience

Volumn 21, Issue 22, 2001, Pages 8842-8853

  Schinelli, Sergio ^a,b   Zanassi, Patrizia ^b   Paolillo, Mayra ^b   Wang, Hang ^a   Feliciello, Antonio ^c   Gallo, Vittorio ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b UNIVERSITY OF PAVIA   (Italy)

^c CNR   (Italy)

Author keywords

Elk 1; Glia; Protein kinase C; Raf kinase; Rap1; Ribosomal S6 kinase

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ENDOTHELIN B RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; RAF PROTEIN; RAP PROTEIN; RAS PROTEIN; RECEPTOR SUBTYPE; S6 KINASE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL CULTURE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

EID: 0035890158     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-22-08842.2001     Document Type: Article

References (52)

1. The mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression
2. Identification of p90RSK as the probable CREB-Ser133 kinase in human melanocytes
3. All in the family? New insight and questions regarding interconnectivity of Ras, Rap 1 and Ral
4. Increasing complexity of Ras signaling
5. Growth factor activity of endothelin-1 in primary astrocytes mediated by adhesion-dependent and -independent pathway
6. Regulation of ras-GTP loading and ras-raf association in neonatal rat ventricular myocites by G protein-coupled receptor agonists and phorbol ester
7. Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy
8. Differential effects of cAMP in neurons and astrocytes
9. Endothelin-1 and smooth muscle cells: Induction of jun amino-terminal kinase through an oxygen radical-sensitive mechanism
10. Biphasic activation of p21ras by endothelin-1 sequentially activates the ERK cascade and phosphatidylinositol 3-kinase
11. 2+-mediated activation of Rap1 in human platelets
12. Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction
13. Developmental and growth factor induced regulation of nestin in oligodendrocyte lineage cells
14. Thrombopoietin-mediated sustained activation of extracellular signalregulated kinase in UT7-Mp1 cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathways
15. Inhibition of cyclin E-cyclin-dependent kinase 2 complex formation and activity is associated with cell cycle arrest and withdrawal in oligodendrocyte progenitor cells
16. 1 cell cycle arrest in oligodendrocyte progenitors
17. The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades
18. Isotype specific functions of Raf kinases
19. Atrial natriuretic peptide inhibits endothelin-1-induced activation of JNK in glomerular mesangial cells
20. AP-1 function and regulation
21. Role of Rho GTPase in the endothelin-1-induced nuclear signaling
22. Physiological role of brain endothelin in the central autonomic control: From neuron to knockout mouse
23. Endothelins stimulate c-fos and nerve growth factor expression in astrocytes and astrocytoma
24. B endothelin receptor to mitogen-activated protein kinase stimulation and DNA synthesis in primary cultures of rat astrocytes
25. Endothelin-1 stimulates c-fos mRNA expression in C6 glioma cells via MAPKinase pathway
26. Physiology and pharmacology of endothelins
27. Activation of the Rap1GTPase by the B cell antigen receptor
28. Induction of astrocyte differentiation by endothelial cells
29. JNK and p38 stress kinasedegenerative effectors of signal-transduction-cascades in the nervous system
30. Activation of MAPK cascades by G-protein-coupled receptors: The case of gonadotropin-releasmg hormone receptor
31. Endothelin peptides in brain diseases
32. Rap1A protein interferes with various MAP kinase activating pathways in skeletal myogenic cells
33. The small GTPase, Rap1, mediates CD31-induced integrin adhesion
34. Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements
35. Endothelins: Molecular biology, biochemistry, pharmacology, physiology, and pathophysiology
36. Mitogen-activated protein kinases: Specific messages from ubiquitous messengers
37. 2-adrenergic receptor activates extracellular signal-regulated kinases (ERKs) via the small G protein Rap1 and the serine/threonine kinase B-Raf
38. Activation of mitogen-activated protein kinase by the A(2A)-adenosine receptor via a Rap1-dependent and via a p21(ras)-dependent pathway
39. CREB: A stimulus-induced transcription factor activated by a diverse array of extracellular signals
40. The neuronglia signal beta neuregulin induces sustained CREB phosphorylation on Ser-133 in cultured rat Schwann cells
41. FGF and stress regulate CREB and ATF-1 via pathway involving p38 MAP kinase and MAPKAP kinase-2
42. The stress-activated protein kinase pathways
43. Say NO to ET
44. Glutamate induces phosphorylation of Elk-1 and CREB, along with c-fos activation, via an extracellular signal-regulated kinase-dependent pathway in brain slices
45. Activation of the c-fos enhancer by the erk MAP kinase pathway through two sequence elements: The c-fos AP-1 and p62TCF sites
46. Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways
47. Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation
48. Stimulation of c-fos and c-jun gene expression and down-regulation of proenkephalin gene expression in C6 glioma cells by endothelin-1
49. Rap1 mediates sustained MAP kinase activation induced by nerve growth factor
50. Reactions of astrocytes and microglial cells around hematogenous metastases of the human brain. Expression of endothelin-like immunoreactivity in reactive astrocytes and activation of microglial cells
51. Hematogenous metastases of the human brain-characteristics of peritumoral brain changes: A review
52. Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling