The anti-apoptotic and growth stimulatory actions of leptin in human colon cancer cells involves activation of JNK mitogen activated protein kinase, JAK2 and PI3 kinase/Akt

International Journal of Colorectal Disease

Volumn 22, Issue 4, 2007, Pages 401-409

  Ogunwobi, Olorunseun O ^b   Beales, Ian L P ^a,b  

^a NORFOLK AND NORWICH UNIVERSITY HOSPITAL   (United Kingdom)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

Activator protein 1; Akt; Apoptosis; c JunNH2 terminal kinase; Celecoxib; Coloncancer; Janus tyrosine kinase 2; Leptin; Proliferation; STAT3 protein

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CELECOXIB; JANUS KINASE 2; LEPTIN; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER INCIDENCE; CELL PROLIFERATION; CELL STRAIN HT29; COLON CANCER; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GENE ACTIVATION; HUMAN; HUMAN CELL; NUCLEOSOME; OBESITY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; CELL DIVISION; CELL LINE, TUMOR; COLONIC NEOPLASMS; ENZYME ACTIVATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JANUS KINASE 2; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LEPTIN; PHOSPHOTRANSFERASES; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 33847369824     PISSN: 01791958     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00384-006-0181-y     Document Type: Article

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