Leptin induces apoptosis via ERK/cPLA2/cytochrome c pathway in human bone marrow stromal cells

Journal of Biological Chemistry

Volumn 278, Issue 24, 2003, Pages 21920-21929

  Kim, Ghi Su ^a   Hong, Jeong Soo ^b,c   Kim, Seung Wook ^b   Koh, Jung Min ^a   An, Chung Sun ^c   Choi, Je Yong ^d   Cheng, Su Li ^e  

^a University of Ulsan College of Medicine   (South Korea)

^b Asan Institute for Life Sciences   (South Korea)

^c Seoul National University   (South Korea)

^d Kyungpook National University   (South Korea)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; ENZYME INHIBITION; ENZYMES; TOXIC MATERIALS;

CYTOCHROMES;

BONE;

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; CYTOCHROME C; GENE PRODUCT; LEPTIN; LEPTIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE);

APOPTOSIS; ARTICLE; BONE MASS; CELL DEATH; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; ENZYME ACTIVATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ALKALINE PHOSPHATASE; APOPTOSIS; ARACHIDONIC ACID; AZO COMPOUNDS; BLOTTING, NORTHERN; BONE MARROW CELLS; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELL SEPARATION; CELLS, CULTURED; COLORING AGENTS; CYTOCHROME C GROUP; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; LEPTIN; MITOGEN-ACTIVATED PROTEIN KINASES; OSTEOCALCIN; POLY(ADP-RIBOSE) POLYMERASES; PRECIPITIN TESTS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; STROMAL CELLS; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 0037821691     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M204598200     Document Type: Article

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