A Wnt-CKIε-Rap1 Pathway Regulates Gastrulation by Modulating SIPA1L1, a Rap GTPase Activating Protein

Developmental Cell

Volumn 12, Issue 3, 2007, Pages 335-347

  Tsai, I Chun ^a   Amack, Jeffrey D ^a   Gao, Zhong Hua ^a   Band, Vimla ^b   Yost, H Joseph ^a   Virshup, David M ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

DEVBIO; SIGNALING

Indexed keywords

BETA CATENIN; CASEIN KINASE IEPSILON; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; RAP1 PROTEIN; SIGNAL INDUCED PROLIFERATION ASSOCIATED PROTEIN 1 LIKE 1; UNCLASSIFIED DRUG; WNT PROTEIN; SIPA1L1 PROTEIN, ZEBRAFISH; WNT8A PROTEIN, XENOPUS; XENOPUS PROTEIN; ZEBRAFISH PROTEIN;

ANIMAL CELL; ANTERIOR POSTERIOR AXIS; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME INHIBITION; GASTRULATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; XENOPUS; ZEBRA FISH; ANIMAL; CELL LINE; CYTOLOGY; EMBRYO DEVELOPMENT; GASTRULA; GENETICS; METABOLISM; MORPHOGENESIS; PHOSPHORYLATION; PHYSIOLOGY;

DANIO RERIO; VERTEBRATA;

ANIMALS; BETA CATENIN; BODY PATTERNING; CASEIN KINASE IEPSILON; CELL LINE; EMBRYONIC DEVELOPMENT; ENZYME ACTIVATION; GASTRULA; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GTPASE-ACTIVATING PROTEINS; HUMANS; PHOSPHORYLATION; RAP1 GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; WNT PROTEINS; XENOPUS; XENOPUS PROTEINS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 33847231810     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2007.02.009     Document Type: Article

References (54)

1. Choi S.C., and Han J.K. Rap2 is required for Wnt/β-catenin signaling pathway in Xenopus early development. EMBO J. 24 (2005) 985-996
2. Christian J.L., and Moon R.T. Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus. Genes Dev. 7 (1993) 13-28
3. Crawford N.P., Ziogas A., Peel D.J., Hess J., Anton-Culver H., and Hunter K.W. Germline polymorphisms in SIPA1 are associated with metastasis and other indicators of poor prognosis in breast cancer. Breast Cancer Res. 8 (2006) R16
4. Eide E.J., Vielhaber E.L., Hinz W.A., and Virshup D.M. The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase Iε. J. Biol. Chem. 277 (2002) 17248-17254
5. Essner J.J., Branford W.W., Zhang J., and Yost H.J. Mesendoderm and left-right brain, heart and gut development are differentially regulated by pitx2 isoforms. Development 127 (2000) 1081-1093
6. Essner J.J., Amack J.D., Nyholm M.K., Harris E.B., and Yost H.J. Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut. Development 132 (2005) 1247-1260
7. Fanto M., Weber U., Strutt D.I., and Mlodzik M. Nuclear signaling by Rac and Rho GTPases is required in the establishment of epithelial planar polarity in the Drosophila eye. Curr. Biol. 10 (2000) 979-988
8. Franke B., van Triest M., de Bruijn K.M., van Willigen G., Nieuwenhuis H.K., Negrier C., Akkerman J.W., and Bos J.L. Sequential regulation of the small GTPase Rap1 in human platelets. Mol. Cell. Biol. 20 (2000) 779-785
9. Gao Q., Srinivasan S., Boyer S.N., Wazer D.E., and Band V. The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation. Mol. Cell. Biol. 19 (1999) 733-744
10. Gao Z.H., Metherall J., and Virshup D.M. Identification of casein kinase I substrates by in vitro expression cloning screening. Biochem. Biophys. Res. Commun. 268 (2000) 562-566
11. Gao Q., Singh L., Kumar A., Srinivasan S., Wazer D.E., and Band V. Human papillomavirus type 16 E6-induced degradation of E6TP1 correlates with its ability to immortalize human mammary epithelial cells. J. Virol. 75 (2001) 4459-4466
12. Gao Z.H., Seeling J.M., Hill V., Yochum A., and Virshup D.M. Casein kinase I phosphorylates and destabilizes the β-catenin degradation complex. Proc. Natl. Acad. Sci. USA 99 (2002) 1182-1187
13. Gietzen K.F., and Virshup D.M. Identification of inhibitory autophosphorylation sites in casein kinase I ε. J. Biol. Chem. 274 (1999) 32063-32070
14. Habas R., Kato Y., and He X. Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1. Cell 107 (2001) 843-854
15. Habas R., Dawid I.B., and He X. Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation. Genes Dev. 17 (2003) 295-309
16. Harland R.M. In situ hybridization: an improved whole-mount method for Xenopus embryos. Methods Cell Biol. 36 (1991) 685-695
17. Heisenberg C.P., and Nusslein-Volhard C. The function of silberblick in the positioning of the eye anlage in the zebrafish embryo. Dev. Biol. 184 (1997) 85-94
18. Heisenberg C.P., Tada M., Rauch G.J., Saude L., Concha M.L., Geisler R., Stemple D.L., Smith J.C., and Wilson S.W. Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. Nature 405 (2000) 76-81
19. Jopling C., and den Hertog J. Fyn/Yes and non-canonical Wnt signalling converge on RhoA in vertebrate gastrulation cell movements. EMBO Rep. 6 (2005) 426-431
20. Keller R. Shaping the vertebrate body plan by polarized embryonic cell movements. Science 298 (2002) 1950-1954
21. Kimura-Yoshida C., Nakano H., Okamura D., Nakao K., Yonemura S., Belo J.A., Aizawa S., Matsui Y., and Matsuo I. Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm. Dev. Cell 9 (2005) 639-650
22. Klein T.J., Jenny A., Djiane A., and Mlodzik M. CKIε/discs overgrown promotes both Wnt-Fz/β-catenin and Fz/PCP signaling in Drosophila. Curr. Biol. 16 (2006) 1337-1343
23. Knippschild U., Gocht A., Wolff S., Huber N., Lohler J., and Stoter M. The casein kinase 1 family: participation in multiple cellular processes in eukaryotes. Cell. Signal. 17 (2005) 675-689
24. 2+ pathway: a new vertebrate Wnt signaling pathway takes shape. Trends Genet. 16 (2000) 279-283
25. Logan C.Y., and Nusse R. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20 (2004) 781-810
26. Marlow F., Topczewski J., Sepich D., and Solnica-Krezel L. Zebrafish Rho kinase 2 acts downstream of Wnt11 to mediate cell polarity and effective convergence and extension movements. Curr. Biol. 12 (2002) 876-884
27. Mashhoon N., Carmel G., Pflugrath J.W., and Kuret J. Structure of the unliganded cAMP-dependent protein kinase catalytic subunit from Saccharomyces cerevisiae. Arch. Biochem. Biophys. 387 (2001) 11-19
28. McKay R.M., Peters J.M., and Graff J.M. The casein kinase I family: roles in morphogenesis. Dev. Biol. 235 (2001) 378-387
29. McLeod S.J., Li A.H., Lee R.L., Burgess A.E., and Gold M.R. The Rap GTPases regulate B cell migration toward the chemokine stromal cell-derived factor-1 (CXCL12): potential role for Rap2 in promoting B cell migration. J. Immunol. 169 (2002) 1365-1371
30. Pak D.T., Yang S., Rudolph-Correia S., Kim E., and Sheng M. Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP. Neuron 31 (2001) 289-303
31. Park Y.G., Zhao X., Lesueur F., Lowy D.R., Lancaster M., Pharoah P., Qian X., and Hunter K.W. Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1. Nat. Genet. 37 (2005) 1055-1062
32. Peters J.M., McKay R.M., McKay J.P., and Graff J.M. Casein kinase I transduces Wnt signals. Nature 401 (1999) 345-350
33. Polakis P. Wnt signaling and cancer. Genes Dev. 14 (2000) 1837-1851
34. Price M.A. CKI, there's more than one: casein kinase I family members in Wnt and Hedgehog signaling. Genes Dev. 20 (2006) 399-410
35. Reya T., and Clevers H. Wnt signalling in stem cells and cancer. Nature 434 (2005) 843-850
36. Sakanaka C., Leong P., Xu L., Harrison S.D., and Williams L.T. Casein kinase Iε in the wnt pathway: regulation of β-catenin function. Proc. Natl. Acad. Sci. USA 96 (1999) 12548-12552
37. Saneyoshi T., Kume S., Amasaki Y., and Mikoshiba K. The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos. Nature 417 (2002) 295-299
38. Sato A., Khadka D.K., Liu W., Bharti R., Runnels L.W., Dawid I.B., and Habas R. Profilin is an effector for Daam1 in non-canonical Wnt signaling and is required for vertebrate gastrulation. Development 133 (2006) 4219-4231
39. Singh L., Gao Q., Kumar A., Gotoh T., Wazer D.E., Band H., Feig L.A., and Band V. The high-risk human papillomavirus type 16 E6 counters the GAP function of E6TP1 toward small Rap G proteins. J. Virol. 77 (2003) 1614-1620
40. Sokol S.Y. Analysis of Dishevelled signalling pathways during Xenopus development. Curr. Biol. 6 (1996) 1456-1467
41. Solnica-Krezel L. Conserved patterns of cell movements during vertebrate gastrulation. Curr. Biol. 15 (2005) R213-R228
42. Strutt D.I., Weber U., and Mlodzik M. The role of RhoA in tissue polarity and Frizzled signalling. Nature 387 (1997) 292-295
43. Strutt H., Price M.A., and Strutt D. Planar polarity is positively regulated by casein kinase Iε in Drosophila. Curr. Biol. 16 (2006) 1329-1336
44. Swiatek W., Tsai I.C., Klimowski L., Pepler A., Barnette J., Yost H.J., and Virshup D.M. Regulation of casein kinase I ε activity by Wnt signaling. J. Biol. Chem. 279 (2004) 13011-13017
45. Tada M., and Smith J.C. Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway. Development 127 (2000) 2227-2238
46. Tahinci E., and Symes K. Distinct functions of Rho and Rac are required for convergent extension during Xenopus gastrulation. Dev. Biol. 259 (2003) 318-335
47. Tamada M., Sheetz M.P., and Sawada Y. Activation of a signaling cascade by cytoskeleton stretch. Dev. Cell 7 (2004) 709-718
48. Tao Q., Yokota C., Puck H., Kofron M., Birsoy B., Yan D., Asashima M., Wylie C.C., Lin X., and Heasman J. Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos. Cell 120 (2005) 857-871
49. Veeman M.T., Axelrod J.D., and Moon R.T. A second canon. Functions and mechanisms of β-catenin-independent Wnt signaling. Dev. Cell 5 (2003) 367-377
50. Vossler M.R., Yao H., York R.D., Pan M.G., Rim C.S., and Stork P.J. cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell 89 (1997) 73-82
51. Wallingford J.B., Vogeli K.M., and Harland R.M. Regulation of convergent extension in Xenopus by Wnt5a and Frizzled-8 is independent of the canonical Wnt pathway. Int. J. Dev. Biol. 45 (2001) 225-227
52. Wallingford J.B., Fraser S.E., and Harland R.M. Convergent extension. The molecular control of polarized cell movement during embryonic development. Dev. Cell 2 (2002) 695-706
53. Westfall T.A., Brimeyer R., Twedt J., Gladon J., Olberding A., Furutani-Seiki M., and Slusarski D.C. Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/β-catenin activity. J. Cell Biol. 162 (2003) 889-898
54. Xu Q., Wang Y., Dabdoub A., Smallwood P.M., Williams J., Woods C., Kelley M.W., Jiang L., Tasman W., Zhang K., and Nathans J. Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell 116 (2004) 883-895