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Volumn 3, Issue 3, 2006, Pages 367-372

Type 1 diabetes: Islet inflammation - the contribution of cytokines and beta cells

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; CELL ADHESION MOLECULE; CHECKPOINT KINASE 1; CYTOKINE; FREE RADICAL; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INTERLEUKIN 1; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

EID: 33847189211     PISSN: 17406765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddmec.2006.09.010     Document Type: Review
Times cited : (13)

References (65)
  • 1
    • 0033978827 scopus 로고    scopus 로고
    • Subsets of macrophages and dendritic cells in nonobese diabetic mouse pancreatic inflammatory infiltrates: correlation with the development of diabetes
    • Rosmalen J.G., et al. Subsets of macrophages and dendritic cells in nonobese diabetic mouse pancreatic inflammatory infiltrates: correlation with the development of diabetes. Lab. Invest. 80 (2000) 23-30
    • (2000) Lab. Invest. , vol.80 , pp. 23-30
    • Rosmalen, J.G.1
  • 2
    • 0036108526 scopus 로고    scopus 로고
    • Abnormalities in dendritic cell and macrophage accumulation in the pancreas of nonobese diabetic (NOD) mice during the early neonatal period
    • Charre S., et al. Abnormalities in dendritic cell and macrophage accumulation in the pancreas of nonobese diabetic (NOD) mice during the early neonatal period. Histol. Histopathol. 17 (2002) 393-401
    • (2002) Histol. Histopathol. , vol.17 , pp. 393-401
    • Charre, S.1
  • 3
    • 0028223127 scopus 로고
    • Immunohistochemical characterization of monocytes-macrophages and dendritic cells involved in the initiation of the insulitis and beta-cell destruction in NOD mice
    • Jansen A., et al. Immunohistochemical characterization of monocytes-macrophages and dendritic cells involved in the initiation of the insulitis and beta-cell destruction in NOD mice. Diabetes 43 (1994) 667-675
    • (1994) Diabetes , vol.43 , pp. 667-675
    • Jansen, A.1
  • 4
    • 0029978038 scopus 로고    scopus 로고
    • Checkpoints in the progression of autoimmune disease: lessons from diabetes models
    • Andre I., et al. Checkpoints in the progression of autoimmune disease: lessons from diabetes models. Proc. Natl. Acad. Sci. U S A 93 (1996) 2260-2263
    • (1996) Proc. Natl. Acad. Sci. U S A , vol.93 , pp. 2260-2263
    • Andre, I.1
  • 5
    • 1942443115 scopus 로고    scopus 로고
    • Oxidative stress in type 1 diabetes
    • Haskins K., et al. Oxidative stress in type 1 diabetes. Ann. N. Y. Acad. Sci. 1005 (2003) 43-54
    • (2003) Ann. N. Y. Acad. Sci. , vol.1005 , pp. 43-54
    • Haskins, K.1
  • 6
    • 23844531972 scopus 로고    scopus 로고
    • Evidence for an enhanced adhesion of DC to fibronectin and a role of CCL19 and CCL21 in the accumulation of DC around the pre-diabetic islets in NOD mice
    • Bouma G., et al. Evidence for an enhanced adhesion of DC to fibronectin and a role of CCL19 and CCL21 in the accumulation of DC around the pre-diabetic islets in NOD mice. Eur. J. Immunol. 35 (2005) 2386-2396
    • (2005) Eur. J. Immunol. , vol.35 , pp. 2386-2396
    • Bouma, G.1
  • 7
    • 21744452118 scopus 로고    scopus 로고
    • CCR7 ligand-enhanced phagocytosis of various antigens in mature dendritic cells-time course and antigen distribution different from phagocytosis in immature dendritic cells
    • Kikuchi K., et al. CCR7 ligand-enhanced phagocytosis of various antigens in mature dendritic cells-time course and antigen distribution different from phagocytosis in immature dendritic cells. Microbiol. Immunol. 49 (2005) 535-544
    • (2005) Microbiol. Immunol. , vol.49 , pp. 535-544
    • Kikuchi, K.1
  • 8
    • 12344312102 scopus 로고    scopus 로고
    • NOD mice have a severely impaired ability to recruit leukocytes into sites of inflammation
    • Bouma G., et al. NOD mice have a severely impaired ability to recruit leukocytes into sites of inflammation. Eur. J. Immunol. 35 (2005) 225-235
    • (2005) Eur. J. Immunol. , vol.35 , pp. 225-235
    • Bouma, G.1
  • 9
    • 0035892872 scopus 로고    scopus 로고
    • A ligand for the chemokine receptor CCR7 can influence the homeostatic proliferation of CD4 T cells and progression of autoimmunity
    • Ploix C., et al. A ligand for the chemokine receptor CCR7 can influence the homeostatic proliferation of CD4 T cells and progression of autoimmunity. J. Immunol. 167 (2001) 6724-6730
    • (2001) J. Immunol. , vol.167 , pp. 6724-6730
    • Ploix, C.1
  • 10
    • 0031952961 scopus 로고    scopus 로고
    • Independent genetic regulation of T-cell and antigen-presenting cell participation in autoimmune islet inflammation
    • Fox C.J., and Danska J.S. Independent genetic regulation of T-cell and antigen-presenting cell participation in autoimmune islet inflammation. Diabetes 47 (1998) 331-338
    • (1998) Diabetes , vol.47 , pp. 331-338
    • Fox, C.J.1    Danska, J.S.2
  • 11
    • 33644843857 scopus 로고    scopus 로고
    • Interleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1
    • Steer S.A., et al. Interleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1. PLoS Med. 3 (2005) e17
    • (2005) PLoS Med. , vol.3
    • Steer, S.A.1
  • 12
    • 0025753951 scopus 로고
    • Activated macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide generation
    • Kröncke K.-D., et al. Activated macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide generation. Biochem. Biophys. Res. Commun. 175 (1991) 752-758
    • (1991) Biochem. Biophys. Res. Commun. , vol.175 , pp. 752-758
    • Kröncke, K.-D.1
  • 13
    • 0029984682 scopus 로고    scopus 로고
    • Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues
    • Lenzen S., et al. Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues. Free Radic. Biol. Med. 20 (1996) 463-466
    • (1996) Free Radic. Biol. Med. , vol.20 , pp. 463-466
    • Lenzen, S.1
  • 14
    • 0030689041 scopus 로고    scopus 로고
    • Relation between antioxidant enzyme gene-expression and antioxidative defense status of insulin-producing cells
    • Tiedge M., et al. Relation between antioxidant enzyme gene-expression and antioxidative defense status of insulin-producing cells. Diabetes 46 (1997) 1733-1742
    • (1997) Diabetes , vol.46 , pp. 1733-1742
    • Tiedge, M.1
  • 15
    • 0035793058 scopus 로고    scopus 로고
    • Unusual resistance of ALR/Lt beta cells to autoimmune destruction: role for beta cell expressed resistance determinants
    • Mathews C.E., et al. Unusual resistance of ALR/Lt beta cells to autoimmune destruction: role for beta cell expressed resistance determinants. Proc. Natl. Acad. Sci. USA 98 (2001) 235-240
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 235-240
    • Mathews, C.E.1
  • 16
    • 23244450300 scopus 로고    scopus 로고
    • Mechanisms underlying resistance of pancreatic islets from ALR/Lt mice to cytokine-induced destruction
    • Mathews C.E., et al. Mechanisms underlying resistance of pancreatic islets from ALR/Lt mice to cytokine-induced destruction. J. Immunol. 175 (2005) 1248-1256
    • (2005) J. Immunol. , vol.175 , pp. 1248-1256
    • Mathews, C.E.1
  • 17
    • 0034949349 scopus 로고    scopus 로고
    • An inhibitor of inducible nitric oxide synthase and scavenger of peroxynitrite prevents diabetes development in NOD mice
    • Suarez-Pinzon W.L., et al. An inhibitor of inducible nitric oxide synthase and scavenger of peroxynitrite prevents diabetes development in NOD mice. J. Autoimmun. 16 (2001) 449-455
    • (2001) J. Autoimmun. , vol.16 , pp. 449-455
    • Suarez-Pinzon, W.L.1
  • 18
    • 0032710718 scopus 로고    scopus 로고
    • Resistance of ALR/Lt Islets to free radical mediated diabetogenic stress is inherited as a dominant trait
    • Mathews C., and Leiter E. Resistance of ALR/Lt Islets to free radical mediated diabetogenic stress is inherited as a dominant trait. Diabetes 48 (1999) 2189-2196
    • (1999) Diabetes , vol.48 , pp. 2189-2196
    • Mathews, C.1    Leiter, E.2
  • 19
    • 2342502747 scopus 로고    scopus 로고
    • Superoxide, nitric oxide, peroxynitrite and cytokine combinations all cause functional impairment and morphological changes in rat islets of Langerhans and insulin secreting cell lines, but dictate cell death by different mechanisms
    • Di Matteo M.A., et al. Superoxide, nitric oxide, peroxynitrite and cytokine combinations all cause functional impairment and morphological changes in rat islets of Langerhans and insulin secreting cell lines, but dictate cell death by different mechanisms. Apoptosis 2 (1997) 164-177
    • (1997) Apoptosis , vol.2 , pp. 164-177
    • Di Matteo, M.A.1
  • 20
    • 0032867196 scopus 로고    scopus 로고
    • Constitutive differences in anti-oxidant defense status distinguish alloxan resistant (ALR/Lt) and alloxan susceptible (ALS/Lt) mice
    • Mathews C., and Leiter E. Constitutive differences in anti-oxidant defense status distinguish alloxan resistant (ALR/Lt) and alloxan susceptible (ALS/Lt) mice. Free Radic. Biol. Med. 27 (1999) 449-455
    • (1999) Free Radic. Biol. Med. , vol.27 , pp. 449-455
    • Mathews, C.1    Leiter, E.2
  • 21
    • 33746918518 scopus 로고    scopus 로고
    • Nitric oxide rather than superoxide or peroxynitrite inhibits insulin secretion and causes DNA damage in HIT-T15 cells
    • Delaney C.A., et al. Nitric oxide rather than superoxide or peroxynitrite inhibits insulin secretion and causes DNA damage in HIT-T15 cells. Adv. Exp. Med. Biol. 426 (1997) 335-339
    • (1997) Adv. Exp. Med. Biol. , vol.426 , pp. 335-339
    • Delaney, C.A.1
  • 22
    • 0035912784 scopus 로고    scopus 로고
    • Nitric oxide partitioning into mitochondrial membranes and the control of respiration at cytochrome c oxidase
    • Shiva S., et al. Nitric oxide partitioning into mitochondrial membranes and the control of respiration at cytochrome c oxidase. Proc. Natl. Acad. Sci. USA 98 (2001) 7212-7217
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 7212-7217
    • Shiva, S.1
  • 23
    • 0141706702 scopus 로고    scopus 로고
    • Protein tyrosine nitration in the mitochondria from diabetic mouse heart. Implications to dysfunctional mitochondria in diabetes
    • Turko I.V., et al. Protein tyrosine nitration in the mitochondria from diabetic mouse heart. Implications to dysfunctional mitochondria in diabetes. J. Biol. Chem. 278 (2003) 33972-33977
    • (2003) J. Biol. Chem. , vol.278 , pp. 33972-33977
    • Turko, I.V.1
  • 24
    • 0030684124 scopus 로고    scopus 로고
    • Irreversible inhibition of metabolic function and islet destruction after a 36-hour exposure to interleukin-1-beta
    • Scarim A.L., et al. Irreversible inhibition of metabolic function and islet destruction after a 36-hour exposure to interleukin-1-beta. Endocrinology 138 (1997) 5301-5307
    • (1997) Endocrinology , vol.138 , pp. 5301-5307
    • Scarim, A.L.1
  • 25
    • 3543008400 scopus 로고    scopus 로고
    • Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite and S-nitrosothiols
    • Brown G.C., and Borutaite V. Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite and S-nitrosothiols. Biochim. Biophys. Acta 1658 (2004) 44-49
    • (2004) Biochim. Biophys. Acta , vol.1658 , pp. 44-49
    • Brown, G.C.1    Borutaite, V.2
  • 26
    • 4444261780 scopus 로고    scopus 로고
    • HMGB1 is an endogenous immune adjuvant released by necrotic cells
    • Rovere-Querini P., et al. HMGB1 is an endogenous immune adjuvant released by necrotic cells. EMBO Rep. 5 (2004) 825-830
    • (2004) EMBO Rep. , vol.5 , pp. 825-830
    • Rovere-Querini, P.1
  • 27
    • 0026510118 scopus 로고
    • Cytotoxic effects of cytokines on rat islets: evidence for involvement of free radicals and lipid peroxidation
    • Rabinovitch A., et al. Cytotoxic effects of cytokines on rat islets: evidence for involvement of free radicals and lipid peroxidation. Diabetologia 35 (1992) 409-413
    • (1992) Diabetologia , vol.35 , pp. 409-413
    • Rabinovitch, A.1
  • 28
    • 0028900805 scopus 로고
    • Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase
    • Corbett J.A., and Mcdaniel M.L. Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase. J. Exp. Med. 181 (1995) 559-568
    • (1995) J. Exp. Med. , vol.181 , pp. 559-568
    • Corbett, J.A.1    Mcdaniel, M.L.2
  • 29
    • 0030997703 scopus 로고    scopus 로고
    • Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1
    • Heitmeier M.R., et al. Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1. J. Biol. Chem. 272 (1997) 13697-13704
    • (1997) J. Biol. Chem. , vol.272 , pp. 13697-13704
    • Heitmeier, M.R.1
  • 30
    • 0027243274 scopus 로고
    • What are the types and cellular sources of free radicals in the pathogenesis of insulin dependent (type 1) diabetes mellitus?
    • Mandrup-Poulsen T., et al. What are the types and cellular sources of free radicals in the pathogenesis of insulin dependent (type 1) diabetes mellitus?. Diabetologia 36 (1993) 470-473
    • (1993) Diabetologia , vol.36 , pp. 470-473
    • Mandrup-Poulsen, T.1
  • 31
    • 0027788115 scopus 로고
    • IL-1 beta induces the coexpression of both nitric oxide synthase and cyclooxygenase by islets of Langerhans - activation of cyclooxygenase by nitric oxide
    • Corbett J.A., et al. IL-1 beta induces the coexpression of both nitric oxide synthase and cyclooxygenase by islets of Langerhans - activation of cyclooxygenase by nitric oxide. Biochemistry 32 (1993) 13767-13770
    • (1993) Biochemistry , vol.32 , pp. 13767-13770
    • Corbett, J.A.1
  • 32
    • 0035208918 scopus 로고    scopus 로고
    • Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells
    • Lakey J.R., et al. Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells. Lab. Invest. 81 (2001) 1683-1692
    • (2001) Lab. Invest. , vol.81 , pp. 1683-1692
    • Lakey, J.R.1
  • 33
    • 20444407654 scopus 로고    scopus 로고
    • Increased expression of NAD(P)H oxidase in islets of animal models of Type 2 diabetes and its improvement by an AT1 receptor antagonist
    • Nakayama M., et al. Increased expression of NAD(P)H oxidase in islets of animal models of Type 2 diabetes and its improvement by an AT1 receptor antagonist. Biochem. Biophys. Res. Commun. 332 (2005) 927-933
    • (2005) Biochem. Biophys. Res. Commun. , vol.332 , pp. 927-933
    • Nakayama, M.1
  • 34
    • 0037645789 scopus 로고    scopus 로고
    • Pancreatic beta-cells express phagocyte-like NAD(P)H oxidase
    • Oliveira H.R., et al. Pancreatic beta-cells express phagocyte-like NAD(P)H oxidase. Diabetes 52 (2003) 1457-1463
    • (2003) Diabetes , vol.52 , pp. 1457-1463
    • Oliveira, H.R.1
  • 35
    • 0029922662 scopus 로고    scopus 로고
    • Strain-dependent differences in sensitivity of rat beta-cells to interleukin 1 beta in vitro and in vivo: association with islet nitric oxide synthesis
    • Reimers J., et al. Strain-dependent differences in sensitivity of rat beta-cells to interleukin 1 beta in vitro and in vivo: association with islet nitric oxide synthesis. Diabetes 45 (1996) 771-778
    • (1996) Diabetes , vol.45 , pp. 771-778
    • Reimers, J.1
  • 36
    • 0031871335 scopus 로고    scopus 로고
    • An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus
    • Rabinovitch A. An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus. Diabetes Metab. Rev. 14 (1998) 129-151
    • (1998) Diabetes Metab. Rev. , vol.14 , pp. 129-151
    • Rabinovitch, A.1
  • 37
    • 0036068246 scopus 로고    scopus 로고
    • Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production
    • Thomas H.E., et al. Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production. Diabetes 51 (2002) 311-316
    • (2002) Diabetes , vol.51 , pp. 311-316
    • Thomas, H.E.1
  • 38
    • 0032523104 scopus 로고    scopus 로고
    • Cytokines and their roles in pancreatic islet beta cell destruction and insulin dependent diabetes mellitus
    • Rabinovitch A., and Suarez-Pinzon W.L. Cytokines and their roles in pancreatic islet beta cell destruction and insulin dependent diabetes mellitus. Biochem. Pharmacol. 55 (1998) 1139-1149
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1139-1149
    • Rabinovitch, A.1    Suarez-Pinzon, W.L.2
  • 39
    • 0034808955 scopus 로고    scopus 로고
    • Cytokine-induced inhibition of insulin release from mouse pancreatic beta-cells deficient in inducible nitric oxide synthase
    • Andersson A.K., et al. Cytokine-induced inhibition of insulin release from mouse pancreatic beta-cells deficient in inducible nitric oxide synthase. Biochem. Biophys. Res. Commun. 281 (2001) 396-403
    • (2001) Biochem. Biophys. Res. Commun. , vol.281 , pp. 396-403
    • Andersson, A.K.1
  • 40
    • 0031757110 scopus 로고    scopus 로고
    • Heat shock inhibits cytokine-induced nitric oxide synthase expression by rat and human islets
    • Scarim A.L., et al. Heat shock inhibits cytokine-induced nitric oxide synthase expression by rat and human islets. Endocrinology 139 (1998) 5050-5057
    • (1998) Endocrinology , vol.139 , pp. 5050-5057
    • Scarim, A.L.1
  • 41
    • 33645092675 scopus 로고    scopus 로고
    • Perturbations in nuclear factor-kappaB or c-Jun N-terminal kinase pathways in pancreatic beta cells confer susceptibility to cytokine-induced cell death
    • Thomas H.E., et al. Perturbations in nuclear factor-kappaB or c-Jun N-terminal kinase pathways in pancreatic beta cells confer susceptibility to cytokine-induced cell death. Immunol. Cell Biol. 84 (2006) 20-27
    • (2006) Immunol. Cell Biol. , vol.84 , pp. 20-27
    • Thomas, H.E.1
  • 42
    • 0035983492 scopus 로고    scopus 로고
    • NFkappaB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes
    • Mabley J.G., et al. NFkappaB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes. J. Endocrinol. 173 (2002) 457-464
    • (2002) J. Endocrinol. , vol.173 , pp. 457-464
    • Mabley, J.G.1
  • 43
    • 0032961837 scopus 로고    scopus 로고
    • Stimulation of hyaluronan synthesis by tumor necrosis factor-alpha is mediated by the p50/p65 NF-kappa B complex in MRC-5 myofibroblasts
    • Ohkawa T., et al. Stimulation of hyaluronan synthesis by tumor necrosis factor-alpha is mediated by the p50/p65 NF-kappa B complex in MRC-5 myofibroblasts. Biochim. Biophys. Acta 1448 (1999) 416-424
    • (1999) Biochim. Biophys. Acta , vol.1448 , pp. 416-424
    • Ohkawa, T.1
  • 44
    • 1342280372 scopus 로고    scopus 로고
    • ICAM-1 expression is highly NF-κB-dependent in A549 cells: no role for ERK or p38 MAPK
    • Holden N.S., et al. ICAM-1 expression is highly NF-κB-dependent in A549 cells: no role for ERK or p38 MAPK. Eur. J. Biochem. 271 (2004) 785-791
    • (2004) Eur. J. Biochem. , vol.271 , pp. 785-791
    • Holden, N.S.1
  • 45
    • 0031738502 scopus 로고    scopus 로고
    • Soluble forms of intercellular adhesion molecule-1 inhibit insulitis and onset of autoimmune diabetes [in process citation]
    • Martin S., et al. Soluble forms of intercellular adhesion molecule-1 inhibit insulitis and onset of autoimmune diabetes [in process citation]. Diabetologia 41 (1998) 1298-1303
    • (1998) Diabetologia , vol.41 , pp. 1298-1303
    • Martin, S.1
  • 46
    • 0035446261 scopus 로고    scopus 로고
    • Dominant role of intercellular adhesion molecule-1 in the pathogenesis of autoimmune diabetes in non-obese diabetic mice
    • Martin S., et al. Dominant role of intercellular adhesion molecule-1 in the pathogenesis of autoimmune diabetes in non-obese diabetic mice. J. Autoimmun. 17 (2001) 109-117
    • (2001) J. Autoimmun. , vol.17 , pp. 109-117
    • Martin, S.1
  • 47
    • 10844268104 scopus 로고    scopus 로고
    • Alpha L-integrin I domain cyclic peptide antagonist selectively inhibits T cell adhesion to pancreatic islet microvascular endothelium
    • Huang M., et al. Alpha L-integrin I domain cyclic peptide antagonist selectively inhibits T cell adhesion to pancreatic islet microvascular endothelium. Am. J. Physiol. Gastrointest Liver Physiol. 288 (2005) G67-G73
    • (2005) Am. J. Physiol. Gastrointest Liver Physiol. , vol.288
    • Huang, M.1
  • 48
    • 12344331229 scopus 로고    scopus 로고
    • Differential stimulation of three forms of hyaluronan synthase by TGF-beta, IL-1beta, and TNF-alpha
    • Oguchi T., and Ishiguro N. Differential stimulation of three forms of hyaluronan synthase by TGF-beta, IL-1beta, and TNF-alpha. Connect. Tissue Res. 45 (2004) 197-205
    • (2004) Connect. Tissue Res. , vol.45 , pp. 197-205
    • Oguchi, T.1    Ishiguro, N.2
  • 49
    • 23044475571 scopus 로고    scopus 로고
    • Inhibition of membrane type-1 matrix metalloproteinase by cancer drugs interferes with the homing of diabetogenic T cells into the pancreas
    • Savinov A.Y., et al. Inhibition of membrane type-1 matrix metalloproteinase by cancer drugs interferes with the homing of diabetogenic T cells into the pancreas. J. Biol. Chem. 280 (2005) 27755-27758
    • (2005) J. Biol. Chem. , vol.280 , pp. 27755-27758
    • Savinov, A.Y.1
  • 50
    • 0030800122 scopus 로고    scopus 로고
    • Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice
    • Itoh N., et al. Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice. J. Exp. Med. 186 (1997) 613-618
    • (1997) J. Exp. Med. , vol.186 , pp. 613-618
    • Itoh, N.1
  • 51
    • 0037457891 scopus 로고    scopus 로고
    • Contribution of Fas to diabetes development
    • Savinov A.Y., et al. Contribution of Fas to diabetes development. Proc. Natl. Acad. Sci. U S A 100 (2003) 628-632
    • (2003) Proc. Natl. Acad. Sci. U S A , vol.100 , pp. 628-632
    • Savinov, A.Y.1
  • 52
    • 0033621893 scopus 로고    scopus 로고
    • IL-1 alpha, IL-1 beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes
    • Amrani A., et al. IL-1 alpha, IL-1 beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes. J. Clin. Invest. 105 (2000) 459-468
    • (2000) J. Clin. Invest. , vol.105 , pp. 459-468
    • Amrani, A.1
  • 53
    • 0345016500 scopus 로고    scopus 로고
    • Aminoguanidine downregulates expression of cytokine-induced Fas and inducible nitric oxide synthase but not cytokine-enhanced surface antigens of rat islet cells
    • Kuttler B., et al. Aminoguanidine downregulates expression of cytokine-induced Fas and inducible nitric oxide synthase but not cytokine-enhanced surface antigens of rat islet cells. Biochem. Pharmacol. 66 (2003) 2437-2448
    • (2003) Biochem. Pharmacol. , vol.66 , pp. 2437-2448
    • Kuttler, B.1
  • 54
    • 0032531099 scopus 로고    scopus 로고
    • IFN-gamma action on pancreatic beta cells causes class I MHC upregulation but not diabetes
    • Thomas H.E., et al. IFN-gamma action on pancreatic beta cells causes class I MHC upregulation but not diabetes. J. Clin. Invest. 102 (1998) 1249-1257
    • (1998) J. Clin. Invest. , vol.102 , pp. 1249-1257
    • Thomas, H.E.1
  • 55
    • 0029948898 scopus 로고    scopus 로고
    • Genetic absence of gamma-interferon delays but does not prevent diabetes in NOD mice
    • Hultgren B., et al. Genetic absence of gamma-interferon delays but does not prevent diabetes in NOD mice. Diabetes 45 (1996) 812-817
    • (1996) Diabetes , vol.45 , pp. 812-817
    • Hultgren, B.1
  • 56
    • 0033669375 scopus 로고    scopus 로고
    • Interferon-gamma receptor signaling is dispensable in the development of autoimmune type 1 diabetes in NOD mice
    • Serreze D.V., et al. Interferon-gamma receptor signaling is dispensable in the development of autoimmune type 1 diabetes in NOD mice. Diabetes 49 (2000) 2007-2011
    • (2000) Diabetes , vol.49 , pp. 2007-2011
    • Serreze, D.V.1
  • 57
    • 0035863721 scopus 로고    scopus 로고
    • Th1 to Th2 cytokine shifts in NOD mice: sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation
    • Serreze D., et al. Th1 to Th2 cytokine shifts in NOD mice: sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation. J. Immunol. 166 (2001) 1352-1359
    • (2001) J. Immunol. , vol.166 , pp. 1352-1359
    • Serreze, D.1
  • 58
    • 0034175965 scopus 로고    scopus 로고
    • Protection of nonobese diabetic mice from diabetes by gene(s) closely linked to IFN-gamma receptor loci
    • Kanagawa O., et al. Protection of nonobese diabetic mice from diabetes by gene(s) closely linked to IFN-gamma receptor loci. J. Immunol. 164 (2000) 3919-3923
    • (2000) J. Immunol. , vol.164 , pp. 3919-3923
    • Kanagawa, O.1
  • 59
    • 0347086154 scopus 로고    scopus 로고
    • Caspase-1 is not required for type 1 diabetes in the NOD mouse
    • Schott W.H., et al. Caspase-1 is not required for type 1 diabetes in the NOD mouse. Diabetes 53 (2004) 99-104
    • (2004) Diabetes , vol.53 , pp. 99-104
    • Schott, W.H.1
  • 60
    • 0347360367 scopus 로고    scopus 로고
    • IL-1 receptor deficiency slows progression to diabetes in the NOD mouse
    • Thomas H.E., et al. IL-1 receptor deficiency slows progression to diabetes in the NOD mouse. Diabetes 53 (2004) 113-121
    • (2004) Diabetes , vol.53 , pp. 113-121
    • Thomas, H.E.1
  • 61
    • 0035576007 scopus 로고    scopus 로고
    • IFN-gamma affects homing of diabetogenic T cells
    • Savinov A.Y., et al. IFN-gamma affects homing of diabetogenic T cells. J. Immunol. 167 (2001) 6637-6643
    • (2001) J. Immunol. , vol.167 , pp. 6637-6643
    • Savinov, A.Y.1
  • 62
    • 0033526068 scopus 로고    scopus 로고
    • In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha
    • Pakala S.V., et al. In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha. J. Exp. Med. 189 (1999) 1053-1062
    • (1999) J. Exp. Med. , vol.189 , pp. 1053-1062
    • Pakala, S.V.1
  • 63
    • 0033981504 scopus 로고    scopus 로고
    • Re-evaluation of the major histocompatibility complex genes of the NOD-progenitor CTS/Shi strain
    • Mathews C.E., et al. Re-evaluation of the major histocompatibility complex genes of the NOD-progenitor CTS/Shi strain. Diabetes 49 (2000) 131-134
    • (2000) Diabetes , vol.49 , pp. 131-134
    • Mathews, C.E.1
  • 64
    • 0036061614 scopus 로고    scopus 로고
    • A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone
    • Piganelli J.D., et al. A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone. Diabetes 51 (2002) 347-355
    • (2002) Diabetes , vol.51 , pp. 347-355
    • Piganelli, J.D.1
  • 65
    • 0030220093 scopus 로고    scopus 로고
    • The use of aminoguanidine, a selective iNOS inhibitor, to evaluate the role of nitric oxide in the development of autoimmune
    • Corbett J.A., and McDaniel M.L. The use of aminoguanidine, a selective iNOS inhibitor, to evaluate the role of nitric oxide in the development of autoimmune. Diabetes Methods 10 (1996) 21-30
    • (1996) Diabetes Methods , vol.10 , pp. 21-30
    • Corbett, J.A.1    McDaniel, M.L.2


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